S100 Calcium-Binding Protein A4
"S100 Calcium-Binding Protein A4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS.
| Descriptor ID |
D000071999
|
| MeSH Number(s) |
D12.776.157.125.750.813
|
| Concept/Terms |
S100 Calcium-Binding Protein A4- S100 Calcium-Binding Protein A4
- S100 Calcium Binding Protein A4
- Metastasin Protein
- Placental Calcium-Binding Protein
- Calcium-Binding Protein, Placental
- Placental Calcium Binding Protein
- Calvasculin Protein
- Fibroblast-Specific Protein 1
- Fibroblast Specific Protein 1
- S100A4 Protein
|
Below are MeSH descriptors whose meaning is more general than "S100 Calcium-Binding Protein A4".
Below are MeSH descriptors whose meaning is more specific than "S100 Calcium-Binding Protein A4".
This graph shows the total number of publications written about "S100 Calcium-Binding Protein A4" by people in this website by year, and whether "S100 Calcium-Binding Protein A4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 2 | 3 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "S100 Calcium-Binding Protein A4" by people in Profiles.
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Quantification of mRNA Expression Using Single-Molecule Nanopore Sensing. ACS Nano. 2020 10 27; 14(10):13964-13974.
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Oligomeric S100A4 Is Associated With Monocyte Innate Immune Memory and Bypass of Tolerance to Subsequent Stimulation With Lipopolysaccharides. Front Immunol. 2019; 10:791.
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S100A4+ Macrophages Are Necessary for Pulmonary Fibrosis by Activating Lung Fibroblasts. Front Immunol. 2018; 9:1776.
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Effects of selexipag and its active metabolite in contrasting the profibrotic myofibroblast activity in cultured scleroderma skin fibroblasts. Arthritis Res Ther. 2018 05 02; 20(1):77.
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miR-296 inhibits the metastasis and epithelial-mesenchymal transition of colorectal cancer by targeting S100A4. BMC Cancer. 2017 02 16; 17(1):140.
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Epithelial mesenchymal transition (EMT) and non-small cell lung cancer (NSCLC): a mutual association with airway disease. Med Oncol. 2017 Mar; 34(3):45.
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Endothelial-to-mesenchymal transition contributes to endothelial dysfunction and dermal fibrosis in systemic sclerosis. Ann Rheum Dis. 2017 May; 76(5):924-934.