"Gene Deletion" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic rearrangement through loss of segments of DNA or RNA, bringing sequences which are normally separated into close proximity. This deletion may be detected using cytogenetic techniques and can also be inferred from the phenotype, indicating a deletion at one specific locus.
| Descriptor ID |
D017353
|
| MeSH Number(s) |
G05.365.590.762.320 G05.558.800.320
|
| Concept/Terms |
Gene Deletion- Gene Deletion
- Deletion, Gene
- Deletions, Gene
- Gene Deletions
|
Below are MeSH descriptors whose meaning is more general than "Gene Deletion".
Below are MeSH descriptors whose meaning is more specific than "Gene Deletion".
This graph shows the total number of publications written about "Gene Deletion" by people in this website by year, and whether "Gene Deletion" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 4 | 5 |
| 2006 | 0 | 3 | 3 |
| 2007 | 0 | 5 | 5 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 2 | 2 |
| 2013 | 0 | 3 | 3 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 4 | 4 |
| 2017 | 8 | 28 | 36 |
| 2018 | 10 | 31 | 41 |
| 2019 | 3 | 16 | 19 |
| 2020 | 2 | 2 | 4 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Gene Deletion" by people in Profiles.
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Whole-genome sequencing of SARS-CoV-2 reveals the detection of G614 variant in Pakistan. PLoS One. 2021; 16(3):e0248371.
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A tissue- and gender-specific regulation of the SARS-CoV-2 receptor ACE2 by p53 in pigs. Biochem Biophys Res Commun. 2021 05 14; 553:25-29.
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SARS-CoV-2 variants combining spike mutations and the absence of ORF8 may be more transmissible and require close monitoring. Biochem Biophys Res Commun. 2021 04 23; 550:8-14.
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Case Report: Severe Complement-Mediated Thrombotic Microangiopathy in IgG4-Related Disease Secondary to Anti-Factor H IgG4 Autoantibodies. Front Immunol. 2020; 11:604759.
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Genomic monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response. Cell Host Microbe. 2021 03 10; 29(3):489-502.e8.
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Naturally occurring SARS-CoV-2 gene deletions close to the spike S1/S2 cleavage site in the viral quasispecies of COVID19 patients. Emerg Microbes Infect. 2020 Dec; 9(1):1900-1911.
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Loss of orf3b in the circulating SARS-CoV-2 strains. Emerg Microbes Infect. 2020 Dec; 9(1):2685-2696.
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Deletion in the C-terminal region of the envelope glycoprotein in some of the Indian SARS-CoV-2 genome. Virus Res. 2021 01 02; 291:198222.
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Neutralizing monoclonal antibody fails to recognize porcine epidemic diarrhea virus with two regions deleted in spike protein. Vet Microbiol. 2020 Dec; 251:108917.
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Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study. Lancet. 2020 08 29; 396(10251):603-611.