"Tretinoin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE).
| Descriptor ID |
D014212
|
| MeSH Number(s) |
D02.455.326.271.665.202.495.818.500 D02.455.426.392.368.367.379.249.700.860.500 D02.455.849.131.495.818.800 D23.767.261.700.780
|
| Concept/Terms |
Tretinoin- Tretinoin
- Retinoic Acid
- Acid, Retinoic
- Vitamin A Acid
- Acid, Vitamin A
- all-trans-Retinoic Acid
- Acid, all-trans-Retinoic
- all trans Retinoic Acid
- trans-Retinoic Acid
- Acid, trans-Retinoic
- trans Retinoic Acid
|
Below are MeSH descriptors whose meaning is more general than "Tretinoin".
Below are MeSH descriptors whose meaning is more specific than "Tretinoin".
This graph shows the total number of publications written about "Tretinoin" by people in this website by year, and whether "Tretinoin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 11 | 3 | 14 |
| 2018 | 5 | 9 | 14 |
| 2019 | 3 | 0 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tretinoin" by people in Profiles.
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All-Trans Retinoic Acid Exhibits Antiviral Effect against SARS-CoV-2 by Inhibiting 3CLpro Activity. Viruses. 2021 08 23; 13(8).
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Genomics-guided identification of potential modulators of SARS-CoV-2 entry proteases, TMPRSS2 and Cathepsins B/L. PLoS One. 2021; 16(8):e0256141.
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Immunomodulatory agents as potential therapeutic or preventive strategies for COVID-19. Eur Rev Med Pharmacol Sci. 2021 Jun; 25(11):4174-4184.
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Retinoic acid improves baseline barrier function and attenuates TNF-a-induced barrier leak in human bronchial epithelial cell culture model, 16HBE 14o. PLoS One. 2020; 15(12):e0242536.
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In silico identification of Tretinoin as a SARS-CoV-2 envelope (E) protein ion channel inhibitor. Comput Biol Med. 2020 12; 127:104063.
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COVID-19: Endogenous Retinoic Acid Theory and Retinoic Acid Depletion Syndrome. Med Hypotheses. 2020 Nov; 144:110250.
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[Fever, loss of vision and acute promyelocytic leukemia at the pandemic ward]. Ugeskr Laeger. 2020 07 13; 182(29).
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Acute promyelocytic leukaemia lying under the mask of COVID-19-a diagnostic and therapeutic conundrum. Br J Haematol. 2020 08; 190(4):e248-e250.
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Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages. J Infect Dis. 2020 02 03; 221(4):647-659.
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Eczematous, Pruritic, Brownish Plaque of the Nipple and Areola: A Quiz. Acta Derm Venereol. 2019 Dec 01; 99(13):1317-1318.