"Serial Passage" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Inoculation of a series of animals or in vitro tissue with an infectious bacterium or virus, as in VIRULENCE studies and the development of vaccines.
| Descriptor ID |
D012692
|
| MeSH Number(s) |
E01.370.225.875.837 E05.200.875.837
|
| Concept/Terms |
Serial Passage- Serial Passage
- Passage, Serial
- Passages, Serial
- Serial Passages
|
Below are MeSH descriptors whose meaning is more general than "Serial Passage".
Below are MeSH descriptors whose meaning is more specific than "Serial Passage".
This graph shows the total number of publications written about "Serial Passage" by people in this website by year, and whether "Serial Passage" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 7 | 8 |
| 2018 | 0 | 4 | 4 |
| 2020 | 0 | 3 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Serial Passage" by people in Profiles.
-
Natural and Recombinant SARS-CoV-2 Isolates Rapidly Evolve In Vitro to Higher Infectivity through More Efficient Binding to Heparan Sulfate and Reduced S1/S2 Cleavage. J Virol. 2021 10 13; 95(21):e0135721.
-
Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice. EBioMedicine. 2021 May; 67:103381.
-
SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells. PLoS Pathog. 2021 01; 17(1):e1009233.
-
Might SARS-CoV-2 Have Arisen via Serial Passage through an Animal Host or Cell Culture?: A potential explanation for much of the novel coronavirus' distinctive genome. Bioessays. 2020 10; 42(10):e2000091.
-
Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein. Genome Med. 2020 07 28; 12(1):68.
-
Studying Evolutionary Adaptation of MERS-CoV. Methods Mol Biol. 2020; 2099:3-8.
-
Development of a Mouse-Adapted MERS Coronavirus. Methods Mol Biol. 2020; 2099:161-171.
-
Attenuation of a virulent swine acute diarrhea syndrome coronavirus strain via cell culture passage. Virology. 2019 12; 538:61-70.
-
PI4KIII inhibitor enviroxime impedes the replication of the hepatitis C virus by inhibiting PI3 kinases. J Antimicrob Chemother. 2018 12 01; 73(12):3375-3384.
-
Pathobiological and Genomic Characterization of a Cold-Adapted Infectious Bronchitis Virus (BP-caKII). Viruses. 2018 11 19; 10(11).