"Wnt Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Wnt proteins are a large family of secreted glycoproteins that play essential roles in EMBRYONIC AND FETAL DEVELOPMENT, and tissue maintenance. They bind to FRIZZLED RECEPTORS and act as PARACRINE PROTEIN FACTORS to initiate a variety of SIGNAL TRANSDUCTION PATHWAYS. The canonical Wnt signaling pathway stabilizes the transcriptional coactivator BETA CATENIN.
| Descriptor ID |
D051153
|
| MeSH Number(s) |
D12.776.467.984 D23.529.984
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Wnt Proteins".
Below are MeSH descriptors whose meaning is more specific than "Wnt Proteins".
This graph shows the total number of publications written about "Wnt Proteins" by people in this website by year, and whether "Wnt Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 3 | 9 | 12 |
| 2018 | 3 | 6 | 9 |
| 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Wnt Proteins" by people in Profiles.
-
Wnt5a and Wnt11 as acute respiratory distress syndrome biomarkers for severe acute respiratory syndrome coronavirus 2 patients. Eur Respir J. 2020 11; 56(5).
-
Polymorphisms associated with oral clefts as potential susceptibility markers for oral and breast cancer. Arch Oral Biol. 2019 Mar; 99:9-14.
-
The Role of Wnt Pathway in the Pathogenesis of OA and Its Potential Therapeutic Implications in the Field of Regenerative Medicine. Biomed Res Int. 2018; 2018:7402947.
-
Efficacy of 1,550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/ß-Catenin in Androgenetic Alopecia. Dermatol Surg. 2018 10; 44(10):1295-1303.
-
Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting ß-catenin signaling. Biomed Pharmacother. 2018 Dec; 108:724-733.
-
Wnt signaling in human and mouse breast cancer: Focusing on Wnt ligands, receptors and antagonists. Cancer Sci. 2018 Nov; 109(11):3368-3375.
-
Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis. Proc Natl Acad Sci U S A. 2018 09 25; 115(39):E9135-E9144.
-
Tumor promoter TPA activates Wnt/ß-catenin signaling in a casein kinase 1-dependent manner. Proc Natl Acad Sci U S A. 2018 08 07; 115(32):E7522-E7531.
-
SMYD3 controls a Wnt-responsive epigenetic switch for ASCL2 activation and cancer stem cell maintenance. Cancer Lett. 2018 08 28; 430:11-24.
-
Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder. Transl Psychiatry. 2018 03 06; 8(1):55.