"Immunoconjugates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Combinations of diagnostic or therapeutic substances linked with specific immune substances such as IMMUNOGLOBULINS; MONOCLONAL ANTIBODIES; or ANTIGENS. Often the diagnostic or therapeutic substance is a radionuclide. These conjugates are useful tools for specific targeting of DRUGS and RADIOISOTOPES in the CHEMOTHERAPY and RADIOIMMUNOTHERAPY of certain cancers.
| Descriptor ID |
D018796
|
| MeSH Number(s) |
D12.776.124.790.651.114.580 D12.776.377.715.548.114.580
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Immunoconjugates".
Below are MeSH descriptors whose meaning is more specific than "Immunoconjugates".
This graph shows the total number of publications written about "Immunoconjugates" by people in this website by year, and whether "Immunoconjugates" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 1 | 2 |
| 2017 | 6 | 1 | 7 |
| 2018 | 11 | 2 | 13 |
| 2019 | 6 | 1 | 7 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Immunoconjugates" by people in Profiles.
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A plug-and-play platform of ratiometric bioluminescent sensors for homogeneous immunoassays. Nat Commun. 2021 07 28; 12(1):4586.
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Potential Use of Radiolabeled Antibodies for Imaging and Treatment of COVID-19. J Nucl Med. 2021 07 01; 62(7):1020.
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Revamping the ever-changing landscape of drug development processes in the midst of COVID-19 pandemic. Drug Discov Today. 2021 06; 26(6):1337-1339.
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Reply: Potential Use of Radiolabeled Antibodies for Imaging and Treatment of COVID-19. J Nucl Med. 2021 07 01; 62(7):1020-1021.
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Refreshing the biologic pipeline 2020. Nat Biotechnol. 2021 02; 39(2):135-143.
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A novel rapid detection for SARS-CoV-2 spike 1 antigens using human angiotensin converting enzyme 2 (ACE2). Biosens Bioelectron. 2021 Jan 01; 171:112715.
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Linear epitopes of SARS-CoV-2 spike protein elicit neutralizing antibodies in COVID-19 patients. Cell Mol Immunol. 2020 10; 17(10):1095-1097.
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Therapeutic Targeting of Golgi Phosphoprotein 2 (GOLPH2) with Armed Antibodies: A Preclinical Study of Anti-GOLPH2 Antibody Drug Conjugates in Lung and Colorectal Cancer Models of Patient Derived Xenografts (PDX). Target Oncol. 2019 10; 14(5):577-590.
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Tissue Factor and Cancer: Regulation, Tumor Growth, and Metastasis. Semin Thromb Hemost. 2019 Jun; 45(4):385-395.
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Antibody-Drug Conjugates: Future Directions in Clinical and Translational Strategies to Improve the Therapeutic Index. Clin Cancer Res. 2019 09 15; 25(18):5441-5448.