Lothar Rink

InstitutionRWTH Aachen University
AddressAachen
Germany
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 4 Covid-19 publications, with a maximum of 1 publications in April 2020 and July 2020 and December 2020 and March 2021
    All Publications
    Bar chart showing 109 publications over 19 distinct years, with a maximum of 13 publications in 2010
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wessels I, Rolles B, Slusarenko AJ, Rink L. Zinc deficiency as a possible risk factor for increased susceptibility and severe progression of Corona Virus Disease 19. Br J Nutr. 2022 01 28; 127(2):214-232. PMID: 33641685.
      Citations: 3     Fields:    Translation:Humans
    2. Equils O, Lekaj K, Wu A, Fattani S, Liu G, Rink L. Intra-nasal zinc level relationship to COVID-19 anosmia and type 1 interferon response: A proposal. Laryngoscope Investig Otolaryngol. 2021 Feb; 6(1):21-24. PMID: 33614925.
      Citations: 2     
    3. Wessels I, Rolles B, Rink L. The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis. Front Immunol. 2020; 11:1712. PMID: 32754164.
      Citations: 58     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    4. Skalny AV, Rink L, Ajsuvakova OP, Aschner M, Gritsenko VA, Alekseenko SI, Svistunov AA, Petrakis D, Spandidos DA, Aaseth J, Tsatsakis A, Tinkov AA. Zinc and respiratory tract infections: Perspectives for COVID-19 (Review). Int J Mol Med. 2020 Jul; 46(1):17-26. PMID: 32319538.
      Citations: 129     Fields:    Translation:HumansPHPublic Health
    5. Aster I, Barth LM, Rink L, Wessels I. Alterations in membrane fluidity are involved in inhibition of GM-CSF-induced signaling in myeloid cells by zinc. J Trace Elem Med Biol. 2019 Jul; 54:214-220. PMID: 31109615.
      Citations: 2     Fields:    Translation:HumansCells
    6. Maywald M, Wang F, Rink L. The Intracellular Free Zinc Level Is Vital for Treg Function and a Feasible Tool to Discriminate between Treg and Activated Th Cells. Int J Mol Sci. 2018 Nov 13; 19(11). PMID: 30428511.
      Citations:    Fields:    Translation:HumansCells
    7. Clever K, Schlegel KA, Kniha H, Conrads G, Rink L, Modabber A, Hölzle F, Kniha K. Experimental peri-implant mucositis around titanium and zirconia implants in comparison to a natural tooth: part 1-host-derived immunological parameters. Int J Oral Maxillofac Surg. 2019 Apr; 48(4):554-559. PMID: 30409453.
      Citations:    Fields:    Translation:Humans
    8. Levy W, Schramm KW, Mertes F, Henkelmann B, Maywald M, Uciechowski P, Loa A, Haedrich J, Thiem I, Hollert H, Goerlich R, Bernsmann T, Rink L. Development and validation of a ready to use cryo-EROD assay for the standardized screening of dioxins and dioxin-like compounds in foodstuffs. Food Chem Toxicol. 2018 Dec; 122:206-214. PMID: 30300728.
      Citations:    Fields:    Translation:AnimalsCellsPHPublic Health
    9. Kulik L, Maywald M, Kloubert V, Wessels I, Rink L. Zinc deficiency drives Th17 polarization and promotes loss of Treg cell function. J Nutr Biochem. 2019 01; 63:11-18. PMID: 30316032.
      Citations: 6     Fields:    Translation:HumansCells
    10. Rink L, Wessels I. Editorial GMS special issue. J Trace Elem Med Biol. 2018 12; 50:367. PMID: 30262306.
      Citations:    Fields:    
    11. Lowe N, Rink L. Zn-net special issue. J Trace Elem Med Biol. 2018 09; 49:105. PMID: 29895357.
      Citations:    Fields:    Translation:HumansAnimals
    12. Lienau S, Rink L, Wessels I. The role of zinc in calprotectin expression in human myeloid cells. J Trace Elem Med Biol. 2018 Sep; 49:106-112. PMID: 29895358.
      Citations: 1     Fields:    Translation:HumansCells
    13. Trame S, Wessels I, Haase H, Rink L. A short 18 items food frequency questionnaire biochemically validated to estimate zinc status in humans. J Trace Elem Med Biol. 2018 Sep; 49:285-295. PMID: 29496418.
      Citations: 7     Fields:    Translation:Humans
    14. Maywald M, Wang F, Rink L. Zinc supplementation plays a crucial role in T helper 9 differentiation in allogeneic immune reactions and non-activated T cells. J Trace Elem Med Biol. 2018 Dec; 50:482-488. PMID: 29439842.
      Citations: 6     Fields:    Translation:HumansCells
    15. Kloubert V, Blaabjerg K, Dalgaard TS, Poulsen HD, Rink L, Wessels I. Influence of zinc supplementation on immune parameters in weaned pigs. J Trace Elem Med Biol. 2018 Sep; 49:231-240. PMID: 29402502.
      Citations: 12     Fields:    Translation:AnimalsCells
    16. Haas CM, Maywald M, Goetzenich A, Stoppe C, Rink L. Proton-pump inhibitors elevate infection rate in cardiothoracic surgery patients by influencing PMN function in vitro and in vivo. J Leukoc Biol. 2018 04; 103(4):777-788. PMID: 29350834.
      Citations:    Fields:    Translation:HumansCells
    17. Gao H, Zhao L, Wang H, Xie E, Wang X, Wu Q, Yu Y, He X, Ji H, Rink L, Min J, Wang F. Metal transporter Slc39a10 regulates susceptibility to inflammatory stimuli by controlling macrophage survival. Proc Natl Acad Sci U S A. 2017 12 05; 114(49):12940-12945. PMID: 29180421.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    18. Wessels I, Maywald M, Rink L. Zinc as a Gatekeeper of Immune Function. Nutrients. 2017 Nov 25; 9(12). PMID: 29186856.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    19. Frobel J, Božic T, Lenz M, Uciechowski P, Han Y, Herwartz R, Strathmann K, Isfort S, Panse J, Esser A, Birkhofer C, Gerstenmaier U, Kraus T, Rink L, Koschmieder S, Wagner W. Leukocyte Counts Based on DNA Methylation at Individual Cytosines. Clin Chem. 2018 03; 64(3):566-575. PMID: 29118064.
      Citations: 5     Fields:    Translation:HumansCells
    20. Maywald M, Wessels I, Rink L. Zinc Signals and Immunity. Int J Mol Sci. 2017 Oct 24; 18(10). PMID: 29064429.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    21. Dierichs L, Kloubert V, Rink L. Cellular zinc homeostasis modulates polarization of THP-1-derived macrophages. Eur J Nutr. 2018 Sep; 57(6):2161-2169. PMID: 28687933.
      Citations: 11     Fields:    Translation:HumansCells
    22. Gammoh NZ, Rink L. Zinc in Infection and Inflammation. Nutrients. 2017 Jun 17; 9(6). PMID: 28629136.
      Citations: 124     Fields:    Translation:Humans
    23. Reiber C, Brieger A, Engelhardt G, Hebel S, Rink L, Haase H. Zinc chelation decreases IFN-ß-induced STAT1 upregulation and iNOS expression in RAW 264.7 macrophages. J Trace Elem Med Biol. 2017 Dec; 44:76-82. PMID: 28965604.
      Citations: 4     Fields:    Translation:AnimalsCells
    24. Maywald M, Meurer SK, Weiskirchen R, Rink L. Zinc supplementation augments TGF-ß1-dependent regulatory T cell induction. Mol Nutr Food Res. 2017 03; 61(3). PMID: 27794192.
      Citations: 9     Fields:    Translation:HumansCells
    25. Maywald M, Rink L. Zinc supplementation induces CD4+CD25+Foxp3+ antigen-specific regulatory T cells and suppresses IFN-? production by upregulation of Foxp3 and KLF-10 and downregulation of IRF-1. Eur J Nutr. 2017 Aug; 56(5):1859-1869. PMID: 27260002.
      Citations: 11     Fields:    Translation:HumansCells
    26. Ziegler S, Schettgen T, Beier F, Wilop S, Quinete N, Esser A, Masouleh BK, Ferreira MS, Vankann L, Uciechowski P, Rink L, Kraus T, Brümmendorf TH, Ziegler P. Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure. Arch Toxicol. 2017 Jan; 91(1):289-300. PMID: 27146145.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    27. Dörpinghaus M, Brieger A, Panichkina O, Rink L, Haase H. Lead ions abrogate lipopolysaccharide-induced nitric monoxide toxicity by reducing the expression of STAT1 and iNOS. J Trace Elem Med Biol. 2016 Sep; 37:117-124. PMID: 27134082.
      Citations: 3     Fields:    Translation:AnimalsCells
    28. Haase H, Fahlenkamp A, Schettgen T, Esser A, Gube M, Ziegler P, Kraus T, Rink L. Immunotoxicity Monitoring in a Population Exposed to Polychlorinated Biphenyls. Int J Environ Res Public Health. 2016 Mar 08; 13(3). PMID: 27005643.
      Citations: 5     Fields:    Translation:HumansCellsPHPublic Health
    29. Ariaans K, Heussen N, Schiffer H, Wienert AL, Plümäkers B, Rink L, Wolfart S. Use of molecular indicators of inflammation to assess the biocompatibility of all-ceramic restorations. J Clin Periodontol. 2016 Feb; 43(2):173-9. PMID: 26714449.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    30. Kessels JE, Wessels I, Haase H, Rink L, Uciechowski P. Influence of DNA-methylation on zinc homeostasis in myeloid cells: Regulation of zinc transporters and zinc binding proteins. J Trace Elem Med Biol. 2016 Sep; 37:125-133. PMID: 26905204.
      Citations: 6     Fields:    Translation:HumansCells
    31. Rosenkranz E, Metz CH, Maywald M, Hilgers RD, Weßels I, Senff T, Haase H, Jäger M, Ott M, Aspinall R, Plümäkers B, Rink L. Zinc supplementation induces regulatory T cells by inhibition of Sirt-1 deacetylase in mixed lymphocyte cultures. Mol Nutr Food Res. 2016 Mar; 60(3):661-71. PMID: 26614004.
      Citations: 28     Fields:    Translation:HumansCells
    32. Giacconi R, Costarelli L, Malavolta M, Cardelli M, Galeazzi R, Piacenza F, Gasparini N, Basso A, Mariani E, Fulop T, Rink L, Dedoussis G, Herbein G, Jajte J, Provinciali M, Busco F, Mocchegiani E. Effect of ZIP2 Gln/Arg/Leu (rs2234632) polymorphism on zinc homeostasis and inflammatory response following zinc supplementation. Biofactors. 2015 Nov-Dec; 41(6):414-23. PMID: 26643924.
      Citations: 2     Fields:    Translation:HumansCells
    33. Rosenkranz E, Maywald M, Hilgers RD, Brieger A, Clarner T, Kipp M, Plümäkers B, Meyer S, Schwerdtle T, Rink L. Induction of regulatory T cells in Th1-/Th17-driven experimental autoimmune encephalomyelitis by zinc administration. J Nutr Biochem. 2016 Mar; 29:116-23. PMID: 26895672.
      Citations: 20     Fields:    Translation:AnimalsCells
    34. Rosenkranz E, Hilgers RD, Uciechowski P, Petersen A, Plümäkers B, Rink L. Zinc enhances the number of regulatory T cells in allergen-stimulated cells from atopic subjects. Eur J Nutr. 2017 Mar; 56(2):557-567. PMID: 26589301.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    35. Kloubert V, Rink L. Zinc as a micronutrient and its preventive role of oxidative damage in cells. Food Funct. 2015 Oct; 6(10):3195-204. PMID: 26286461.
      Citations: 27     Fields:    Translation:HumansCells
    36. Hasan R, Rink L, Haase H. Chelation of Free Zn²? Impairs Chemotaxis, Phagocytosis, Oxidative Burst, Degranulation, and Cytokine Production by Neutrophil Granulocytes. Biol Trace Elem Res. 2016 May; 171(1):79-88. PMID: 26400651.
      Citations: 19     Fields:    Translation:HumansCells
    37. Haase H, Hebel S, Engelhardt G, Rink L. Ethylmercury and Hg2+ induce the formation of neutrophil extracellular traps (NETs) by human neutrophil granulocytes. Arch Toxicol. 2016 Mar; 90(3):543-50. PMID: 25701957.
      Citations: 8     Fields:    Translation:HumansCells
    38. Giacconi R, Simm A, Santos AN, Costarelli L, Malavolta M, Mecocci P, Piacenza F, Basso A, Fulop T, Rink L, Dedoussis G, Kanoni S, Herbein G, Jajte J, Mocchegiani E. Influence of +1245 A/G MT1A polymorphism on advanced glycation end-products (AGEs) in elderly: effect of zinc supplementation. Genes Nutr. 2014 Sep; 9(5):426. PMID: 25149676.
      Citations: 3     
    39. Haase H, Rink L. Multiple impacts of zinc on immune function. Metallomics. 2014 Jul; 6(7):1175-80. PMID: 24531756.
      Citations: 55     Fields:    Translation:HumansCells
    40. Mayer LS, Uciechowski P, Meyer S, Schwerdtle T, Rink L, Haase H. Differential impact of zinc deficiency on phagocytosis, oxidative burst, and production of pro-inflammatory cytokines by human monocytes. Metallomics. 2014 Jul; 6(7):1288-95. PMID: 24823619.
      Citations: 24     Fields:    Translation:HumansCells
    41. Plum LM, Brieger A, Engelhardt G, Hebel S, Nessel A, Arlt M, Kaltenberg J, Schwaneberg U, Huber M, Rink L, Haase H. PTEN-inhibition by zinc ions augments interleukin-2-mediated Akt phosphorylation. Metallomics. 2014 Jul; 6(7):1277-87. PMID: 24759986.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    42. Maywald M, Rink L. Zinc homeostasis and immunosenescence. J Trace Elem Med Biol. 2015 Jan; 29:24-30. PMID: 25022332.
      Citations: 13     Fields:    Translation:Humans
    43. Poplutz MK, Wessels I, Rink L, Uciechowski P. Regulation of the Interleukin-6 gene expression during monocytic differentiation of HL-60 cells by chromatin remodeling and methylation. Immunobiology. 2014 Aug; 219(8):619-26. PMID: 24746556.
      Citations: 11     Fields:    Translation:HumansCells
    44. Schmitt V, Rink L, Uciechowski P. The Th17/Treg balance is disturbed during aging. Exp Gerontol. 2013 Dec; 48(12):1379-86. PMID: 24055797.
      Citations: 60     Fields:    Translation:HumansCells
    45. Brieger A, Rink L, Haase H. Differential regulation of TLR-dependent MyD88 and TRIF signaling pathways by free zinc ions. J Immunol. 2013 Aug 15; 191(4):1808-17. PMID: 23863901.
      Citations: 32     Fields:    Translation:AnimalsCells
    46. Haase H, Rink L. Zinc signals and immune function. Biofactors. 2014 Jan-Feb; 40(1):27-40. PMID: 23804522.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    47. Uciechowski P, Oellig EM, Mariani E, Malavolta M, Mocchegiani E, Rink L. Effects of human Toll-like receptor 1 polymorphisms on ageing. Immun Ageing. 2013 Feb 07; 10(1):4. PMID: 23391127.
      Citations: 2     
    48. Haase H, Hebel S, Engelhardt G, Rink L. Application of Zinpyr-1 for the investigation of zinc signals in Escherichia coli. Biometals. 2013 Feb; 26(1):167-77. PMID: 23324851.
      Citations: 5     Fields:    Translation:HumansCells
    49. Wessels I, Rosenkranz E, Ventura Ferreira M, Neuss S, Zenke M, Rink L, Uciechowski P. Activation of IL-1ß and TNFa genes is mediated by the establishment of permissive chromatin structures during monopoiesis. Immunobiology. 2013 Jun; 218(6):860-8. PMID: 23195574.
      Citations: 1     Fields:    Translation:HumansCells
    50. Hasan R, Rink L, Haase H. Zinc signals in neutrophil granulocytes are required for the formation of neutrophil extracellular traps. Innate Immun. 2013 Jun; 19(3):253-64. PMID: 23008348.
      Citations: 26     Fields:    Translation:HumansCells
    51. Daaboul D, Rosenkranz E, Uciechowski P, Rink L. Repletion of zinc in zinc-deficient cells strongly up-regulates IL-1ß-induced IL-2 production in T-cells. Metallomics. 2012 Oct; 4(10):1088-97. PMID: 22983538.
      Citations: 10     Fields:    Translation:AnimalsCells
    52. Jorissen A, Plum LM, Rink L, Haase H. Impact of lead and mercuric ions on the interleukin-2-dependent proliferation and survival of T cells. Arch Toxicol. 2013 Feb; 87(2):249-58. PMID: 22910795.
      Citations: 4     Fields:    Translation:HumansCells
    53. Wessels I, Haase H, Engelhardt G, Rink L, Uciechowski P. Zinc deficiency induces production of the proinflammatory cytokines IL-1ß and TNFa in promyeloid cells via epigenetic and redox-dependent mechanisms. J Nutr Biochem. 2013 Jan; 24(1):289-97. PMID: 22902331.
      Citations: 27     Fields:    Translation:HumansCells
    54. Jansen J, Rosenkranz E, Overbeck S, Warmuth S, Mocchegiani E, Giacconi R, Weiskirchen R, Karges W, Rink L. Disturbed zinc homeostasis in diabetic patients by in vitro and in vivo analysis of insulinomimetic activity of zinc. J Nutr Biochem. 2012 Nov; 23(11):1458-66. PMID: 22402369.
      Citations: 37     Fields:    Translation:HumansCells
    55. Kraus T, Gube M, Lang J, Esser A, Sturm W, Fimm B, Willmes K, Neulen J, Baron JM, Merk H, Schettgen T, Konrad K, Deisz S, Rink L, Hagmann M, Fillies B, Zschiesche W, Wittsiepe J, Wilhelm M. Surveillance program for former PCB-exposed workers of a transformer and capacitor recycling company, family members, employees of surrounding companies, and area residents--executive summary. J Toxicol Environ Health A. 2012; 75(19-20):1241-7. PMID: 22994578.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    56. Uciechowski P, Imhoff H, Lange C, Meyer CG, Browne EN, Kirsten DK, Schröder AK, Schaaf B, Al-Lahham A, Reinert RR, Reiling N, Haase H, Hatzmann A, Fleischer D, Heussen N, Kleines M, Rink L. Susceptibility to tuberculosis is associated with TLR1 polymorphisms resulting in a lack of TLR1 cell surface expression. J Leukoc Biol. 2011 Aug; 90(2):377-88. PMID: 21642391.
      Citations: 32     Fields:    Translation:HumansCells
    57. Hönscheid A, Dubben S, Rink L, Haase H. Zinc differentially regulates mitogen-activated protein kinases in human T cells. J Nutr Biochem. 2012 Jan; 23(1):18-26. PMID: 21333516.
      Citations: 12     Fields:    Translation:HumansCells
    58. Ober-Blöbaum JL, Engelhardt G, Hebel S, Rink L, Haase H. Cadmium ions promote monocytic differentiation of human leukemia HL-60 cells treated with 1a,25-dihydroxyvitamin D3. Biol Chem. 2010 Nov; 391(11):1295-303. PMID: 20868229.
      Citations: 2     Fields:    Translation:HumansCells
    59. Haase H, Engelhardt G, Hebel S, Rink L. Mercuric ions inhibit mitogen-activated protein kinase dephosphorylation by inducing reactive oxygen species. Toxicol Appl Pharmacol. 2011 Jan 01; 250(1):78-86. PMID: 20951154.
      Citations: 4     Fields:    Translation:HumansCells
    60. Lintges M, van der Linden M, Hilgers RD, Arlt S, Al-Lahham A, Reinert RR, Plücken S, Rink L. Superantigen genes are more important than the emm type for the invasiveness of group A Streptococcus infection. J Infect Dis. 2010 Jul 01; 202(1):20-8. PMID: 20497047.
      Citations: 16     Fields:    Translation:HumansCells
    61. Haase H, Ober-Blöbaum JL, Engelhardt G, Hebel S, Rink L. Cadmium ions induce monocytic production of tumor necrosis factor-alpha by inhibiting mitogen activated protein kinase dephosphorylation. Toxicol Lett. 2010 Oct 05; 198(2):152-8. PMID: 20600713.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    62. Kaltenberg J, Plum LM, Ober-Blöbaum JL, Hönscheid A, Rink L, Haase H. Zinc signals promote IL-2-dependent proliferation of T cells. Eur J Immunol. 2010 May; 40(5):1496-503. PMID: 20201035.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    63. Himmerich H, Milenovic S, Fulda S, Plümäkers B, Sheldrick AJ, Michel TM, Kircher T, Rink L. Regulatory T cells increased while IL-1ß decreased during antidepressant therapy. J Psychiatr Res. 2010 Nov; 44(15):1052-7. PMID: 20413130.
      Citations: 42     Fields:    Translation:HumansCells
    64. Bomble M, Tacke F, Rink L, Kovalenko E, Weiskirchen R. Analysis of antigen-presenting functionality of cultured rat hepatic stellate cells and transdifferentiated myofibroblasts. Biochem Biophys Res Commun. 2010 May 28; 396(2):342-7. PMID: 20403338.
      Citations: 12     Fields:    Translation:AnimalsCells
    65. Plum LM, Rink L, Haase H. The essential toxin: impact of zinc on human health. Int J Environ Res Public Health. 2010 04; 7(4):1342-65. PMID: 20617034.
      Citations: 177     Fields:    Translation:HumansPHPublic Health
    66. Sanderson P, Elsom RL, Kirkpatrick V, Calder PC, Woodside JV, Williams EA, Rink L, Fairweather-Tait S, Ivory K, Cantorna M, Watzl B, Stone EM. UK food standards agency workshop report: diet and immune function. Br J Nutr. 2010 Jun; 103(11):1684-7. PMID: 20211037.
      Citations: 3     Fields:    Translation:HumansAnimals
    67. Wessels I, Fleischer D, Rink L, Uciechowski P. Changes in chromatin structure and methylation of the human interleukin-1beta gene during monopoiesis. Immunology. 2010 Jul; 130(3):410-7. PMID: 20141541.
      Citations: 8     Fields:    Translation:HumansCells
    68. Wessels I, Jansen J, Rink L, Uciechowski P. Immunosenescence of polymorphonuclear neutrophils. ScientificWorldJournal. 2010 Jan 21; 10:145-60. PMID: 20098958.
      Citations: 20     Fields:    Translation:HumansCells
    69. Dubben S, Hönscheid A, Winkler K, Rink L, Haase H. Cellular zinc homeostasis is a regulator in monocyte differentiation of HL-60 cells by 1 alpha,25-dihydroxyvitamin D3. J Leukoc Biol. 2010 May; 87(5):833-44. PMID: 20089671.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    70. Himmerich H, Fulda S, Sheldrick AJ, Plümäkers B, Rink L. IFN-gamma reduction by tricyclic antidepressants. Int J Psychiatry Med. 2010; 40(4):413-24. PMID: 21391412.
      Citations: 10     Fields:    Translation:Humans
    71. Haylett RS, Koch N, Rink L. MHC class II molecules activate NFAT and the ERK group of MAPK through distinct signaling pathways in B cells. Eur J Immunol. 2009 Jul; 39(7):1947-55. PMID: 19544309.
      Citations: 11     Fields:    Translation:HumansCells
    72. Haase H, Rink L. The immune system and the impact of zinc during aging. Immun Ageing. 2009 Jun 12; 6:9. PMID: 19523191.
      Citations: 70     
    73. Jansen J, Karges W, Rink L. Zinc and diabetes--clinical links and molecular mechanisms. J Nutr Biochem. 2009 Jun; 20(6):399-417. PMID: 19442898.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    74. Hönscheid A, Rink L, Haase H. T-lymphocytes: a target for stimulatory and inhibitory effects of zinc ions. Endocr Metab Immune Disord Drug Targets. 2009 Jun; 9(2):132-44. PMID: 19519463.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    75. Kanoni S, Dedoussis GV, Herbein G, Fulop T, Varin A, Jajte J, Rink L, Monti D, Mariani E, Malavolta M, Giacconi R, Marcellini F, Mocchegiani E. Assessment of gene-nutrient interactions on inflammatory status of the elderly with the use of a zinc diet score--ZINCAGE study. J Nutr Biochem. 2010 Jun; 21(6):526-31. PMID: 19447023.
      Citations: 12     Fields:    Translation:Humans
    76. Haase H, Rink L. Functional significance of zinc-related signaling pathways in immune cells. Annu Rev Nutr. 2009; 29:133-52. PMID: 19400701.
      Citations: 92     Fields:    Translation:HumansCells
    77. Dlaske H, Karaüzüm H, Monzon-Casanova E, Rudolf R, Starick L, Müller I, Wildner G, Diedrichs-Möhring M, Koch N, Miyoshi-Akiyama T, Uchiyama T, Wonigeit K, Fleischer B, Overbeck S, Rink L, Herrmann T. Superantigen-presentation by rat major histocompatibility complex class II molecules RT1.Bl and RT1.Dl. Immunology. 2009 Sep; 128(1 Suppl):e572-81. PMID: 19740318.
      Citations:    Fields:    Translation:AnimalsCells
    78. Haase H, Ober-Blöbaum JL, Engelhardt G, Hebel S, Heit A, Heine H, Rink L. Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes. J Immunol. 2008 Nov 01; 181(9):6491-502. PMID: 18941240.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    79. Haase H, Hebel S, Engelhardt G, Rink L. Zinc ions cause the thimerosal-induced signal of fluorescent calcium probes in lymphocytes. Cell Calcium. 2009 Feb; 45(2):185-91. PMID: 18977527.
      Citations: 2     Fields:    Translation:HumansCells
    80. Mazzatti DJ, Uciechowski P, Hebel S, Engelhardt G, White AJ, Powell JR, Rink L, Haase H. Effects of long-term zinc supplementation and deprivation on gene expression in human THP-1 mononuclear cells. J Trace Elem Med Biol. 2008; 22(4):325-36. PMID: 19013360.
      Citations: 5     Fields:    Translation:HumansCells
    81. Malavolta M, Cipriano C, Costarelli L, Giacconi R, Tesei S, Muti E, Piacenza F, Pierpaoli S, Larbi A, Pawelec G, Dedoussis G, Herbein G, Monti D, Jajte J, Rink L, Mocchegiani E. Metallothionein downregulation in very old age: a phenomenon associated with cellular senescence? Rejuvenation Res. 2008 Apr; 11(2):455-9. PMID: 18393657.
      Citations: 5     Fields:    Translation:HumansCells
    82. Kahmann L, Uciechowski P, Warmuth S, Plümäkers B, Gressner AM, Malavolta M, Mocchegiani E, Rink L. Zinc supplementation in the elderly reduces spontaneous inflammatory cytokine release and restores T cell functions. Rejuvenation Res. 2008 Feb; 11(1):227-37. PMID: 18279033.
      Citations: 33     Fields:    Translation:HumansCells
    83. Mocchegiani E, Giacconi R, Costarelli L, Muti E, Cipriano C, Tesei S, Pierpaoli S, Giuli C, Papa R, Marcellini F, Gasparini N, Pierandrei R, Piacenza F, Mariani E, Monti D, Dedoussis G, Kanoni S, Herbein G, Fulop T, Rink L, Jajte J, Malavolta M. Zinc deficiency and IL-6 -174G/C polymorphism in old people from different European countries: effect of zinc supplementation. ZINCAGE study. Exp Gerontol. 2008 May; 43(5):433-44. PMID: 18267353.
      Citations: 19     Fields:    Translation:HumansCells
    84. Dedoussis GV, Kanoni S, Mariani E, Cattini L, Herbein G, Fulop T, Varin A, Rink L, Jajte J, Monti D, Marcellini F, Malavolta M, Mocchegiani E. Mediterranean diet and plasma concentration of inflammatory markers in old and very old subjects in the ZINCAGE population study. Clin Chem Lab Med. 2008; 46(7):990-6. PMID: 18605965.
      Citations: 14     Fields:    Translation:Humans
    85. Varin A, Larbi A, Dedoussis GV, Kanoni S, Jajte J, Rink L, Monti D, Malavolta M, Marcellini F, Mocchegiani E, Herbein G, Fulop T. In vitro and in vivo effects of zinc on cytokine signalling in human T cells. Exp Gerontol. 2008 May; 43(5):472-82. PMID: 18249079.
      Citations: 8     Fields:    Translation:HumansCells
    86. Mariani E, Neri S, Cattini L, Mocchegiani E, Malavolta M, Dedoussis GV, Kanoni S, Rink L, Jajte J, Facchini A. Effect of zinc supplementation on plasma IL-6 and MCP-1 production and NK cell function in healthy elderly: interactive influence of +647 MT1a and -174 IL-6 polymorphic alleles. Exp Gerontol. 2008 May; 43(5):462-71. PMID: 18215484.
      Citations: 30     Fields:    Translation:HumansCells
    87. Haase H, Overbeck S, Rink L. Zinc supplementation for the treatment or prevention of disease: current status and future perspectives. Exp Gerontol. 2008 May; 43(5):394-408. PMID: 18221847.
      Citations: 39     Fields:    Translation:HumansPHPublic Health
    88. Uciechowski P, Kahmann L, Plümäkers B, Malavolta M, Mocchegiani E, Dedoussis G, Herbein G, Jajte J, Fulop T, Rink L. TH1 and TH2 cell polarization increases with aging and is modulated by zinc supplementation. Exp Gerontol. 2008 May; 43(5):493-8. PMID: 18166287.
      Citations: 21     Fields:    Translation:HumansCells
    89. Bode U, Lörchner M, Ahrendt M, Blessenohl M, Kalies K, Claus A, Overbeck S, Rink L, Pabst R. Dendritic cell subsets in lymph nodes are characterized by the specific draining area and influence the phenotype and fate of primed T cells. Immunology. 2008 Apr; 123(4):480-90. PMID: 18028375.
      Citations: 6     Fields:    Translation:AnimalsCells
    90. Mocchegiani E, Giacconi R, Cipriano C, Costarelli L, Muti E, Tesei S, Giuli C, Papa R, Marcellini F, Mariani E, Rink L, Herbein G, Varin A, Fulop T, Monti D, Jajte J, Dedoussis G, Gonos ES, Trougakos IP, Malavolta M. Zinc, metallothioneins, and longevity--effect of zinc supplementation: zincage study. Ann N Y Acad Sci. 2007 Nov; 1119:129-46. PMID: 18056962.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    91. Overbeck S, Uciechowski P, Ackland ML, Ford D, Rink L. Intracellular zinc homeostasis in leukocyte subsets is regulated by different expression of zinc exporters ZnT-1 to ZnT-9. J Leukoc Biol. 2008 Feb; 83(2):368-80. PMID: 17971500.
      Citations: 27     Fields:    Translation:HumansCells
    92. von Bülow V, Dubben S, Engelhardt G, Hebel S, Plümäkers B, Heine H, Rink L, Haase H. Zinc-dependent suppression of TNF-alpha production is mediated by protein kinase A-induced inhibition of Raf-1, I kappa B kinase beta, and NF-kappa B. J Immunol. 2007 Sep 15; 179(6):4180-6. PMID: 17785857.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    93. Haase H, Mazzatti DJ, White A, Ibs KH, Engelhardt G, Hebel S, Powell JR, Rink L. Differential gene expression after zinc supplementation and deprivation in human leukocyte subsets. Mol Med. 2007 Jul-Aug; 13(7-8):362-70. PMID: 17622302.
      Citations: 10     Fields:    Translation:HumansCells
    94. Lintges M, Arlt S, Uciechowski P, Plümäkers B, Reinert RR, Al-Lahham A, Lütticken R, Rink L. A new closed-tube multiplex real-time PCR to detect eleven superantigens of Streptococcus pyogenes identifies a strain without superantigen activity. Int J Med Microbiol. 2007 Oct; 297(6):471-8. PMID: 17481952.
      Citations: 13     Fields:    Translation:HumansCells
    95. Haase H, Rink L. Signal transduction in monocytes: the role of zinc ions. Biometals. 2007 Jun; 20(3-4):579-85. PMID: 17453150.
      Citations: 34     Fields:    Translation:HumansCells
    96. Diedershagen M, Overbeck S, Arlt S, Plümäkers B, Lintges M, Rink L. Mycoplasma arthritidis-derived superantigen (MAM) displays DNase activity. FEMS Immunol Med Microbiol. 2007 Mar; 49(2):266-71. PMID: 17328760.
      Citations: 6     Fields:    Translation:Cells
    97. Metz CH, Schröder AK, Overbeck S, Kahmann L, Plümäkers B, Rink L. T-helper type 1 cytokine release is enhanced by in vitro zinc supplementation due to increased natural killer cells. Nutrition. 2007 Feb; 23(2):157-63. PMID: 17150331.
      Citations: 6     Fields:    Translation:HumansCells
    98. Rink L, Haase H. Zinc homeostasis and immunity. Trends Immunol. 2007 Jan; 28(1):1-4. PMID: 17126599.
      Citations: 71     Fields:    Translation:HumansAnimals
    99. Bode U, Lörchner M, Pabst R, Wonigeit K, Overbeck S, Rink L, Hundrieser J. The superantigen-induced polarization of T cells in rat peripheral lymph nodes is influenced by genetic polymorphisms in the IL-4 and IL-6 gene clusters. Int Immunol. 2007 Jan; 19(1):81-92. PMID: 17130183.
      Citations: 1     Fields:    Translation:AnimalsCells
    100. Schröder AK, von der Ohe M, Kolling U, Altstaedt J, Uciechowski P, Fleischer D, Dalhoff K, Ju X, Zenke M, Heussen N, Rink L. Polymorphonuclear leucocytes selectively produce anti-inflammatory interleukin-1 receptor antagonist and chemokines, but fail to produce pro-inflammatory mediators. Immunology. 2006 Nov; 119(3):317-27. PMID: 17067311.
      Citations: 16     Fields:    Translation:HumansCells
    101. Marcellini F, Giuli C, Papa R, Gagliardi C, Dedoussis G, Herbein G, Fulop T, Monti D, Rink L, Jajte J, Mocchegiani E. Zinc status, psychological and nutritional assessment in old people recruited in five European countries: Zincage study. Biogerontology. 2006 Oct-Dec; 7(5-6):339-45. PMID: 16969711.
      Citations: 26     Fields:    Translation:Humans
    102. Kahmann L, Uciechowski P, Warmuth S, Malavolta M, Mocchegiani E, Rink L. Effect of improved zinc status on T helper cell activation and TH1/TH2 ratio in healthy elderly individuals. Biogerontology. 2006 Oct-Dec; 7(5-6):429-35. PMID: 16967204.
      Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
    103. Mocchegiani E, Rink L, Blasco M. Zinc and ageing (ZINCAGE Project). Biogerontology. 2006 Oct-Dec; 7(5-6):305-6. PMID: 16953334.
      Citations: 2     Fields:    Translation:Humans
    104. Haase H, Mocchegiani E, Rink L. Correlation between zinc status and immune function in the elderly. Biogerontology. 2006 Oct-Dec; 7(5-6):421-8. PMID: 16953331.
      Citations: 33     Fields:    Translation:HumansCells
    105. Gross U, Schroder AK, Haylett RS, Arlt S, Rink L. The superantigen staphylococcal enterotoxin A (SEA) and monoclonal antibody L243 share a common epitope but differ in their ability to induce apoptosis via MHC-II. Immunobiology. 2006; 211(10):807-14. PMID: 17113918.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    106. Schröder AK, Uciechowski P, Fleischer D, Rink L. Crosslinking of CD66B on peripheral blood neutrophils mediates the release of interleukin-8 from intracellular storage. Hum Immunol. 2006 Sep; 67(9):676-82. PMID: 17002897.
      Citations: 14     Fields:    Translation:HumansCells
    107. Luhm J, Langenkamp U, Hensel J, Frohn C, Brand JM, Hennig H, Rink L, Koritke P, Wittkopf N, Williams DL, Mueller A. Beta-(1-->3)-D-glucan modulates DNA binding of nuclear factors kappaB, AT and IL-6 leading to an anti-inflammatory shift of the IL-1beta/IL-1 receptor antagonist ratio. BMC Immunol. 2006 Mar 22; 7:5. PMID: 16553947.
      Citations: 7     Fields:    Translation:HumansCells
    108. Haase H, Hebel S, Engelhardt G, Rink L. Flow cytometric measurement of labile zinc in peripheral blood mononuclear cells. Anal Biochem. 2006 May 15; 352(2):222-30. PMID: 16545333.
      Citations: 41     Fields:    Translation:HumansCells
    109. Mocchegiani E, Costarelli L, Giacconi R, Cipriano C, Muti E, Rink L, Malavolta M. Zinc homeostasis in aging: two elusive faces of the same "metal". Rejuvenation Res. 2006; 9(2):351-4. PMID: 16706668.
      Citations: 5     Fields:    Translation:HumansCells
    110. Schröder AK, von der Ohe M, Fleischer D, Rink L, Uciechowski P. Differential synthesis of two interleukin-1 receptor antagonist variants and interleukin-8 by peripheral blood neutrophils. Cytokine. 2005 Dec 07; 32(5):246-53. PMID: 16343927.
      Citations: 3     Fields:    Translation:HumansCells
    111. von Bülow V, Rink L, Haase H. Zinc-mediated inhibition of cyclic nucleotide phosphodiesterase activity and expression suppresses TNF-alpha and IL-1 beta production in monocytes by elevation of guanosine 3',5'-cyclic monophosphate. J Immunol. 2005 Oct 01; 175(7):4697-705. PMID: 16177117.
      Citations: 37     Fields:    Translation:HumansCells
    112. Kreiss M, Asmuss A, Krejci K, Lindemann D, Miyoshi-Akiyama T, Uchiyama T, Rink L, Broeren CP, Herrmann T. Contrasting contributions of complementarity-determining region 2 and hypervariable region 4 of rat BV8S2+ (Vbeta8.2) TCR to the recognition of myelin basic protein and different types of bacterial superantigens. Int Immunol. 2004 May; 16(5):655-63. PMID: 15096488.
      Citations: 10     Fields:    Translation:AnimalsCells
    113. Ibs KH, Rink L. Zinc-altered immune function. J Nutr. 2003 05; 133(5 Suppl 1):1452S-6S. PMID: 12730441.
      Citations: 126     Fields:    Translation:HumansCells
    114. Schröder AK, Rink L. Neutrophil immunity of the elderly. Mech Ageing Dev. 2003 Apr; 124(4):419-25. PMID: 12714248.
      Citations: 23     Fields:    Translation:HumansCells
    115. Gabriel P, Cakman I, Rink L. Overproduction of monokines by leukocytes after stimulation with lipopolysaccharide in the elderly. Exp Gerontol. 2002 Jan-Mar; 37(2-3):235-47. PMID: 11772509.
      Citations: 16     Fields:    Translation:HumansCells