Rachel Toth

InstitutionUniversity of Dundee
AddressUnited Kingdom
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 3 Covid-19 publications, with a maximum of 1 publications in October 2020 and February 2021 and July 2021
    All Publications
    Bar chart showing 56 publications over 18 distinct years, with a maximum of 6 publications in 2007
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Armstrong LA, Lange SM, Dee Cesare V, Matthews SP, Nirujogi RS, Cole I, Hope A, Cunningham F, Toth R, Mukherjee R, Bojkova D, Gruber F, Gray D, Wyatt PG, Cinatl J, Dikic I, Davies P, Kulathu Y. Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies. PLoS One. 2021; 16(7):e0253364. PMID: 34270554.
      Citations: 4     Fields:    Translation:HumansCells
    2. Rihn SJ, Merits A, Bakshi S, Turnbull ML, Wickenhagen A, Alexander AJT, Baillie C, Brennan B, Brown F, Brunker K, Bryden SR, Burness KA, Carmichael S, Cole SJ, Cowton VM, Davies P, Davis C, De Lorenzo G, Donald CL, Dorward M, Dunlop JI, Elliott M, Fares M, da Silva Filipe A, Freitas JR, Furnon W, Gestuveo RJ, Geyer A, Giesel D, Goldfarb DM, Goodman N, Gunson R, Hastie CJ, Herder V, Hughes J, Johnson C, Johnson N, Kohl A, Kerr K, Leech H, Lello LS, Li K, Lieber G, Liu X, Lingala R, Loney C, Mair D, McElwee MJ, McFarlane S, Nichols J, Nomikou K, Orr A, Orton RJ, Palmarini M, Parr YA, Pinto RM, Raggett S, Reid E, Robertson DL, Royle J, Cameron-Ruiz N, Shepherd JG, Smollett K, et al. A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research. PLoS Biol. 2021 02; 19(2):e3001091. PMID: 33630831.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    3. Gordon DE, Hiatt J, Bouhaddou M, Rezelj VV, Ulferts S, Braberg H, Jureka AS, Obernier K, Guo JZ, Batra J, Kaake RM, Weckstein AR, Owens TW, Gupta M, Pourmal S, Titus EW, Cakir M, Soucheray M, McGregor M, Cakir Z, Jang G, O'Meara MJ, Tummino TA, Zhang Z, Foussard H, Rojc A, Zhou Y, Kuchenov D, Hüttenhain R, Xu J, Eckhardt M, Swaney DL, Fabius JM, Ummadi M, Tutuncuoglu B, Rathore U, Modak M, Haas P, Haas KM, Naing ZZC, Pulido EH, Shi Y, Barrio-Hernandez I, Memon D, Petsalaki E, Dunham A, Marrero MC, Burke D, Koh C, Vallet T, Silvas JA, Azumaya CM, Billesbølle C, Brilot AF, Campbell MG, Diallo A, Dickinson MS, Diwanji D, Herrera N, Hoppe N, Kratochvil HT, Liu Y, et al. Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms. Science. 2020 12 04; 370(6521). PMID: 33060197.
      Citations: 143     Fields:    Translation:HumansCells
    4. Chaugule VK, Arkinson C, Toth R, Walden H. Enzymatic preparation of monoubiquitinated FANCD2 and FANCI proteins. Methods Enzymol. 2019; 618:73-104. PMID: 30850063.
      Citations: 5     Fields:    Translation:HumansCells
    5. Andersen JL, Gesser B, Funder ED, Nielsen CJF, Gotfred-Rasmussen H, Rasmussen MK, Toth R, Gothelf KV, Arthur JSC, Iversen L, Nissen P. Dimethyl fumarate is an allosteric covalent inhibitor of the p90 ribosomal S6 kinases. Nat Commun. 2018 10 19; 9(1):4344. PMID: 30341347.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    6. Jowsey P, Morrice NA, Hastie CJ, MacLauchlan H, Toth R, Rouse J. Corrigendum to "Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR" [DNA Repair 6 (2007) 1536-1544]. DNA Repair (Amst). 2018 05; 65:80. PMID: 29449168.
      Citations:    Fields:    
    7. Munoz IM, Jowsey PA, Toth R, Rouse J. Corrigendum: Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage. Nucleic Acids Res. 2017 12 15; 45(22):13094. PMID: 29136188.
      Citations:    Fields:    
    8. Feeney L, Muñoz IM, Lachaud C, Toth R, Appleton PL, Schindler D, Rouse J. RPA-Mediated Recruitment of the E3 Ligase RFWD3 Is Vital for Interstrand Crosslink Repair and Human Health. Mol Cell. 2017 Jun 01; 66(5):610-621.e4. PMID: 28575657.
      Citations: 29     Fields:    Translation:HumansCells
    9. Hunter CJ, Remenyi J, Correa SA, Privitera L, Reyskens KMSE, Martin KJ, Toth R, Frenguelli BG, Arthur JSC. MSK1 regulates transcriptional induction of Arc/Arg3.1 in response to neurotrophins. FEBS Open Bio. 2017 06; 7(6):821-834. PMID: 28593137.
      Citations: 4     Fields:    
    10. Abdul-Sada H, Müller M, Mehta R, Toth R, Arthur JSC, Whitehouse A, Macdonald A. The PP4R1 sub-unit of protein phosphatase PP4 is essential for inhibition of NF-?B by merkel polyomavirus small tumour antigen. Oncotarget. 2017 Apr 11; 8(15):25418-25432. PMID: 28445980.
      Citations: 15     Fields:    Translation:HumansCells
    11. Darling NJ, Toth R, Arthur JS, Clark K. Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophages. Biochem J. 2017 02 15; 474(4):521-537. PMID: 27920213.
      Citations: 22     Fields:    Translation:AnimalsCells
    12. Williams CA, Fernandez-Alonso R, Wang J, Toth R, Gray NS, Findlay GM. Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity. Cell Rep. 2016 08 16; 16(7):1820-8. PMID: 27498864.
      Citations: 18     Fields:    Translation:AnimalsCells
    13. Hoxhaj G, Caddye E, Najafov A, Houde VP, Johnson C, Dissanayake K, Toth R, Campbell DG, Prescott AR, MacKintosh C. The E3 ubiquitin ligase ZNRF2 is a substrate of mTORC1 and regulates its activation by amino acids. Elife. 2016 04 22; 5. PMID: 27244671.
      Citations: 5     Fields:    Translation:Humans
    14. Lachaud C, Slean M, Marchesi F, Lock C, Odell E, Castor D, Toth R, Rouse J. Karyomegalic interstitial nephritis and DNA damage-induced polyploidy in Fan1 nuclease-defective knock-in mice. Genes Dev. 2016 Mar 15; 30(6):639-44. PMID: 26980188.
      Citations: 17     Fields:    Translation:AnimalsCells
    15. Lachaud C, Moreno A, Marchesi F, Toth R, Blow JJ, Rouse J. Ubiquitinated Fancd2 recruits Fan1 to stalled replication forks to prevent genome instability. Science. 2016 Feb 19; 351(6275):846-9. PMID: 26797144.
      Citations: 56     Fields:    Translation:AnimalsCells
    16. Li M, Quan C, Toth R, Campbell DG, MacKintosh C, Wang HY, Chen S. Fasting and Systemic Insulin Signaling Regulate Phosphorylation of Brain Proteins That Modulate Cell Morphology and Link to Neurological Disorders. J Biol Chem. 2015 Dec 11; 290(50):30030-41. PMID: 26499801.
      Citations: 2     Fields:    Translation:HumansCells
    17. Munson MJ, Allen GF, Toth R, Campbell DG, Lucocq JM, Ganley IG. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015 Sep 02; 34(17):2272-90. PMID: 26139536.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    18. Kristariyanto YA, Choi SY, Rehman SA, Ritorto MS, Campbell DG, Morrice NA, Toth R, Kulathu Y. Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations. Biochem J. 2015 Apr 15; 467(2):345-52. PMID: 25723849.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    19. Kristariyanto YA, Abdul Rehman SA, Campbell DG, Morrice NA, Johnson C, Toth R, Kulathu Y. K29-selective ubiquitin binding domain reveals structural basis of specificity and heterotypic nature of k29 polyubiquitin. Mol Cell. 2015 Apr 02; 58(1):83-94. PMID: 25752573.
      Citations: 59     Fields:    Translation:HumansCells
    20. Madeira F, Tinti M, Murugesan G, Berrett E, Stafford M, Toth R, Cole C, MacKintosh C, Barton GJ. 14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides. Bioinformatics. 2015 Jul 15; 31(14):2276-83. PMID: 25735772.
      Citations: 52     Fields:    Translation:HumansCells
    21. Munoz IM, Szyniarowski P, Toth R, Rouse J, Lachaud C. Improved genome editing in human cell lines using the CRISPR method. PLoS One. 2014; 9(10):e109752. PMID: 25303670.
      Citations: 24     Fields:    Translation:HumansCells
    22. Chen Q, Quan C, Xie B, Chen L, Zhou S, Toth R, Campbell DG, Lu S, Shirakawa R, Horiuchi H, Li C, Yang Z, MacKintosh C, Wang HY, Chen S. GARNL1, a major RalGAP a subunit in skeletal muscle, regulates insulin-stimulated RalA activation and GLUT4 trafficking via interaction with 14-3-3 proteins. Cell Signal. 2014 Aug; 26(8):1636-48. PMID: 24768767.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    23. Tinti M, Madeira F, Murugesan G, Hoxhaj G, Toth R, Mackintosh C. ANIA: ANnotation and Integrated Analysis of the 14-3-3 interactome. Database (Oxford). 2014; 2014:bat085. PMID: 24501395.
      Citations: 25     Fields:    Translation:HumansCells
    24. Allen GF, Toth R, James J, Ganley IG. Loss of iron triggers PINK1/Parkin-independent mitophagy. EMBO Rep. 2013 Dec; 14(12):1127-35. PMID: 24176932.
      Citations: 173     Fields:    Translation:HumansCells
    25. Castor D, Nair N, Déclais AC, Lachaud C, Toth R, Macartney TJ, Lilley DM, Arthur JS, Rouse J. Cooperative control of holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases. Mol Cell. 2013 Oct 24; 52(2):221-33. PMID: 24076219.
      Citations: 87     Fields:    Translation:HumansAnimalsCells
    26. Wilson JS, Tejera AM, Castor D, Toth R, Blasco MA, Rouse J. Localization-dependent and -independent roles of SLX4 in regulating telomeres. Cell Rep. 2013 Sep 12; 4(5):853-60. PMID: 23994477.
      Citations: 41     Fields:    Translation:HumansCells
    27. Pauls E, Nanda SK, Smith H, Toth R, Arthur JSC, Cohen P. Two phases of inflammatory mediator production defined by the study of IRAK2 and IRAK1 knock-in mice. J Immunol. 2013 Sep 01; 191(5):2717-30. PMID: 23918981.
      Citations: 45     Fields:    Translation:AnimalsCells
    28. Venigalla RK, McGuire VA, Clarke R, Patterson-Kane JC, Najafov A, Toth R, McCarthy PC, Simeons F, Stojanovski L, Arthur JS. PDK1 regulates VDJ recombination, cell-cycle exit and survival during B-cell development. EMBO J. 2013 Apr 03; 32(7):1008-22. PMID: 23463102.
      Citations: 16     Fields:    Translation:AnimalsCells
    29. MacKenzie KF, Clark K, Naqvi S, McGuire VA, Nöehren G, Kristariyanto Y, van den Bosch M, Mudaliar M, McCarthy PC, Pattison MJ, Pedrioli PG, Barton GJ, Toth R, Prescott A, Arthur JS. PGE(2) induces macrophage IL-10 production and a regulatory-like phenotype via a protein kinase A-SIK-CRTC3 pathway. J Immunol. 2013 Jan 15; 190(2):565-77. PMID: 23241891.
      Citations: 99     Fields:    Translation:AnimalsCells
    30. Neukamm SS, Toth R, Morrice N, Campbell DG, Mackintosh C, Lehmann R, Haering HU, Schleicher ED, Weigert C. Identification of the amino acids 300-600 of IRS-2 as 14-3-3 binding region with the importance of IGF-1/insulin-regulated phosphorylation of Ser-573. PLoS One. 2012; 7(8):e43296. PMID: 22912850.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    31. Tinti M, Johnson C, Toth R, Ferrier DE, Mackintosh C. Evolution of signal multiplexing by 14-3-3-binding 2R-ohnologue protein families in the vertebrates. Open Biol. 2012 Jul; 2(7):120103. PMID: 22870394.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    32. Lee DW, Peggie M, Deak M, Toth R, Gage ZO, Wood N, Schilde C, Kurz T, Knebel A. The Dac-tag, an affinity tag based on penicillin-binding protein 5. Anal Biochem. 2012 Sep 01; 428(1):64-72. PMID: 22705378.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    33. Goh ET, Arthur JS, Cheung PC, Akira S, Toth R, Cohen P. Identification of the protein kinases that activate the E3 ubiquitin ligase Pellino 1 in the innate immune system. Biochem J. 2012 Jan 01; 441(1):339-46. PMID: 22007846.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    34. Johnson C, Tinti M, Wood NT, Campbell DG, Toth R, Dubois F, Geraghty KM, Wong BH, Brown LJ, Tyler J, Gernez A, Chen S, Synowsky S, MacKintosh C. Visualization and biochemical analyses of the emerging mammalian 14-3-3-phosphoproteome. Mol Cell Proteomics. 2011 Oct; 10(10):M110.005751. PMID: 21725060.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    35. Nanda SK, Venigalla RK, Ordureau A, Patterson-Kane JC, Powell DW, Toth R, Arthur JS, Cohen P. Polyubiquitin binding to ABIN1 is required to prevent autoimmunity. J Exp Med. 2011 Jun 06; 208(6):1215-28. PMID: 21606507.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    36. Filippi BM, de los Heros P, Mehellou Y, Navratilova I, Gourlay R, Deak M, Plater L, Toth R, Zeqiraj E, Alessi DR. MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases. EMBO J. 2011 May 04; 30(9):1730-41. PMID: 21423148.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    37. Dissanayake K, Toth R, Blakey J, Olsson O, Campbell DG, Prescott AR, MacKintosh C. ERK/p90(RSK)/14-3-3 signalling has an impact on expression of PEA3 Ets transcription factors via the transcriptional repressor capicúa. Biochem J. 2011 Feb 01; 433(3):515-25. PMID: 21087211.
      Citations: 55     Fields:    Translation:HumansCells
    38. Duro E, Lundin C, Ask K, Sanchez-Pulido L, MacArtney TJ, Toth R, Ponting CP, Groth A, Helleday T, Rouse J. Identification of the MMS22L-TONSL complex that promotes homologous recombination. Mol Cell. 2010 Nov 24; 40(4):632-44. PMID: 21055984.
      Citations: 50     Fields:    Translation:HumansCells
    39. Toh GW, Sugawara N, Dong J, Toth R, Lee SE, Haber JE, Rouse J. Mec1/Tel1-dependent phosphorylation of Slx4 stimulates Rad1-Rad10-dependent cleavage of non-homologous DNA tails. DNA Repair (Amst). 2010 Jun 04; 9(6):718-26. PMID: 20382573.
      Citations: 36     Fields:    Translation:AnimalsCells
    40. Johnson C, Crowther S, Stafford MJ, Campbell DG, Toth R, MacKintosh C. Bioinformatic and experimental survey of 14-3-3-binding sites. Biochem J. 2010 Mar 15; 427(1):69-78. PMID: 20141511.
      Citations: 129     Fields:    Translation:HumansCells
    41. MacKay C, Toth R, Rouse J. Biochemical characterisation of the SWI/SNF family member HLTF. Biochem Biophys Res Commun. 2009 Dec 11; 390(2):187-91. PMID: 19723507.
      Citations: 21     Fields:    Translation:HumansCells
    42. Dubois F, Vandermoere F, Gernez A, Murphy J, Toth R, Chen S, Geraghty KM, Morrice NA, MacKintosh C. Differential 14-3-3 affinity capture reveals new downstream targets of phosphatidylinositol 3-kinase signaling. Mol Cell Proteomics. 2009 Nov; 8(11):2487-99. PMID: 19648646.
      Citations: 41     Fields:    Translation:HumansCells
    43. Muñoz IM, Hain K, Déclais AC, Gardiner M, Toh GW, Sanchez-Pulido L, Heuckmann JM, Toth R, Macartney T, Eppink B, Kanaar R, Ponting CP, Lilley DM, Rouse J. Coordination of structure-specific nucleases by human SLX4/BTBD12 is required for DNA repair. Mol Cell. 2009 Jul 10; 35(1):116-27. PMID: 19595721.
      Citations: 180     Fields:    Translation:HumansCells
    44. Gardiner M, Toth R, Vandermoere F, Morrice NA, Rouse J. Identification and characterization of FUS/TLS as a new target of ATM. Biochem J. 2008 Oct 15; 415(2):297-307. PMID: 18620545.
      Citations: 45     Fields:    Translation:HumansCells
    45. Ananieva O, Darragh J, Johansen C, Carr JM, McIlrath J, Park JM, Wingate A, Monk CE, Toth R, Santos SG, Iversen L, Arthur JS. The kinases MSK1 and MSK2 act as negative regulators of Toll-like receptor signaling. Nat Immunol. 2008 Sep; 9(9):1028-36. PMID: 18690222.
      Citations: 147     Fields:    Translation:AnimalsCells
    46. Chen S, Murphy J, Toth R, Campbell DG, Morrice NA, Mackintosh C. Complementary regulation of TBC1D1 and AS160 by growth factors, insulin and AMPK activators. Biochem J. 2008 Jan 15; 409(2):449-59. PMID: 17995453.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    47. Geraghty KM, Chen S, Harthill JE, Ibrahim AF, Toth R, Morrice NA, Vandermoere F, Moorhead GB, Hardie DG, MacKintosh C. Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR. Biochem J. 2007 Oct 15; 407(2):231-41. PMID: 17617058.
      Citations: 67     Fields:    Translation:HumansCells
    48. Munoz IM, Jowsey PA, Toth R, Rouse J. Phospho-epitope binding by the BRCT domains of hPTIP controls multiple aspects of the cellular response to DNA damage. Nucleic Acids Res. 2007; 35(16):5312-22. PMID: 17690115.
      Citations: 54     Fields:    Translation:HumansCells
    49. Flott S, Alabert C, Toh GW, Toth R, Sugawara N, Campbell DG, Haber JE, Pasero P, Rouse J. Phosphorylation of Slx4 by Mec1 and Tel1 regulates the single-strand annealing mode of DNA repair in budding yeast. Mol Cell Biol. 2007 Sep; 27(18):6433-45. PMID: 17636031.
      Citations: 60     Fields:    Translation:AnimalsCells
    50. Jowsey P, Morrice NA, Hastie CJ, McLauchlan H, Toth R, Rouse J. Characterisation of the sites of DNA damage-induced 53BP1 phosphorylation catalysed by ATM and ATR. DNA Repair (Amst). 2007 Oct 01; 6(10):1536-44. PMID: 17553757.
      Citations: 33     Fields:    Translation:HumansCells
    51. McCoy CE, macdonald A, Morrice NA, Campbell DG, Deak M, Toth R, McIlrath J, Arthur JS. Identification of novel phosphorylation sites in MSK1 by precursor ion scanning MS. Biochem J. 2007 Mar 15; 402(3):491-501. PMID: 17117922.
      Citations: 26     Fields:    Translation:HumansCells
    52. Ross SH, Lindsay Y, Safrany ST, Lorenzo O, Villa F, Toth R, Clague MJ, Downes CP, Leslie NR. Differential redox regulation within the PTP superfamily. Cell Signal. 2007 Jul; 19(7):1521-30. PMID: 17346927.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    53. Jaleel M, Villa F, Deak M, Toth R, Prescott AR, Van Aalten DM, Alessi DR. The ubiquitin-associated domain of AMPK-related kinases regulates conformation and LKB1-mediated phosphorylation and activation. Biochem J. 2006 Mar 15; 394(Pt 3):545-55. PMID: 16396636.
      Citations: 36     Fields:    Translation:HumansCells
    54. Macdonald A, Campbell DG, Toth R, McLauchlan H, Hastie CJ, Arthur JS. Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL. BMC Cell Biol. 2006 Jan 10; 7:1. PMID: 16403219.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    55. Lizcano JM, Göransson O, Toth R, Deak M, Morrice NA, Boudeau J, Hawley SA, Udd L, Mäkelä TP, Hardie DG, Alessi DR. LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1. EMBO J. 2004 Feb 25; 23(4):833-43. PMID: 14976552.
      Citations: 545     Fields:    Translation:HumansCells
    56. Gillespie T, Boevink P, Haupt S, Roberts AG, Toth R, Valentine T, Chapman S, Oparka KJ. Functional analysis of a DNA-shuffled movement protein reveals that microtubules are dispensable for the cell-to-cell movement of tobacco mosaic virus. Plant Cell. 2002 Jun; 14(6):1207-22. PMID: 12084822.
      Citations: 60     Fields:    Translation:AnimalsCells