Emiel F M Wouters

InstitutionMaastricht University Medical Center
AddressThe
Netherlands
vCardDownload vCard
    Publication Timeline
    COVID-19 publications
    Bar chart showing 2 Covid-19 publications, with a maximum of 1 publications in May 2021 and December 2021
    All Publications
    Bar chart showing 362 publications over 19 distinct years, with a maximum of 35 publications in 2013 and 2014
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

    To see the data from both graphs as text, click here.
    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
    Sort By:     Newest   |   Oldest   |   Most Cited   |   Most Discussed
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Dofferhoff ASM, Piscaer I, Schurgers LJ, Visser MPJ, van den Ouweland JMW, de Jong PA, Gosens R, Hackeng TM, van Daal H, Lux P, Maassen C, Karssemeijer EGA, Vermeer C, Wouters EFM, Kistemaker LEM, Walk J, Janssen R. Reduced Vitamin K Status as a Potentially Modifiable Risk Factor of Severe Coronavirus Disease 2019. Clin Infect Dis. 2021 12 06; 73(11):e4039-e4046. PMID: 32852539.
      Citations: 25   Article has an altmetric score of 116    Fields:    Translation:Humans
    2. Breyer MK, Breyer-Kohansal R, Hartl S, Kundi M, Weseslindtner L, Stiasny K, Puchhammer-Stöckl E, Schrott A, Födinger M, Binder M, Fiedler M, Wouters EFM, Burghuber OC. Low SARS-CoV-2 seroprevalence in the Austrian capital after an early governmental lockdown. Sci Rep. 2021 05 12; 11(1):10158. PMID: 33980950.
      Citations: 3   Article has an altmetric score of 6    Fields:    Translation:HumansPHPublic HealthCTClinical Trials
    3. Franssen FME, Vanfleteren LEGW, Janssen DJA, Wouters EFM, Spruit MA. Effects of a comprehensive, inpatient pulmonary rehabilitation programme in a cachectic patient with very severe COPD and chronic respiratory failure. Breathe (Sheff). 2019 Sep; 15(3):227-233. PMID: 31508160.
      Citations: Article has an altmetric score of 15    
    4. Piscaer I, van den Ouweland JMW, Vermeersch K, Reynaert NL, Franssen FME, Keene S, Wouters EFM, Janssens W, Vermeer C, Janssen R. Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease. J Clin Med. 2019 Jul 27; 8(8). PMID: 31357639.
      Citations: 7   Article has an altmetric score of 8    
    5. Janssen DJA, Rechberger S, Wouters EFM, Schols JMGA, Johnson MJ, Currow DC, Curtis JR, Spruit MA. Clustering of 27,525,663 Death Records from the United States Based on Health Conditions Associated with Death: An Example of big Health Data Exploration. J Clin Med. 2019 Jun 27; 8(7). PMID: 31252579.
      Citations: 1   Article has an altmetric score of 2    
    6. Vanfleteren LEGW, Boonen LMC, Spruit MA, Janssen DJA, Wouters EFM, Franssen FME. The superexacerbator phenotype in patients with COPD: a descriptive analysis. ERJ Open Res. 2019 Apr; 5(2). PMID: 31192249.
      Citations: Article has an altmetric score of 50    
    7. Triest FJJ, Studnicka M, Franssen FME, Vollmer WM, Lamprecht B, Wouters EFM, Burney PGJ, Vanfleteren LEGW. Airflow Obstruction and Cardio-metabolic Comorbidities. COPD. 2019 04; 16(2):109-117. PMID: 31131642.
      Citations: 2   Article has an altmetric score of 8    Fields:    Translation:Humans
    8. Oshagbemi OA, Franssen FME, van Kraaij S, Braeken DCW, Wouters EFM, Maitland-van der Zee AH, Driessen JHM, de Vries F. Blood Eosinophil Counts, Withdrawal of Inhaled Corticosteroids and Risk of COPD Exacerbations and Mortality in the Clinical Practice Research Datalink (CPRD). COPD. 2019 04; 16(2):152-159. PMID: 31117850.
      Citations: 6   Article has an altmetric score of 7    Fields:    Translation:HumansCells
    9. Wouters EFM. The Medusa faces of dyspnoea in COPD. Eur Respir J. 2019 Apr; 53(4). PMID: 31000669.
      Citations: Article has an altmetric score of 41    Fields:    Translation:Humans
    10. Triest FJJ, Franssen FME, Reynaert N, Gaffron S, Spruit MA, Janssen DJA, Rutten EPA, Wouters EFM, Vanfleteren LEGW. Disease-Specific Comorbidity Clusters in COPD and Accelerated Aging. J Clin Med. 2019 Apr 14; 8(4). PMID: 31013986.
      Citations: 8   Article has an altmetric score of 15    
    11. Houben-Wilke S, Triest FJJ, Franssen FME, Janssen DJA, Wouters EFM, Vanfleteren LEGW. Revealing Methodological Challenges in Chronic Obstructive Pulmonary Disease Studies Assessing Comorbidities: A Narrative Review. Chronic Obstr Pulm Dis. 2019 Apr 09; 6(2):166-177. PMID: 30974051.
      Citations: 5   Article has an altmetric score of 1    
    12. Spruit MA, Rochester CL, Pitta F, Kenn K, Schols AMWJ, Hart N, Wouters EFM, Nava S, Dreher M, Janssen DJA, Johnson MJ, Curtis RJ, Sastry M, Franssen FME. Pulmonary rehabilitation, physical activity, respiratory failure and palliative respiratory care. Thorax. 2019 07; 74(7):693-699. PMID: 30872364.
      Citations: 1   Article has an altmetric score of 54    Fields:    Translation:Humans
    13. Benedikter BJ, Bouwman FG, Heinzmann ACA, Vajen T, Mariman EC, Wouters EFM, Savelkoul PHM, Koenen RR, Rohde GGU, van Oerle R, Spronk HM, Stassen FRM. Proteomic analysis reveals procoagulant properties of cigarette smoke-induced extracellular vesicles. J Extracell Vesicles. 2019; 8(1):1585163. PMID: 30863515.
      Citations: 8   Article has an altmetric score of 16    
    14. Janssen R, Piscaer I, Franssen FME, Wouters EFM. Emphysema: looking beyond alpha-1 antitrypsin deficiency. Expert Rev Respir Med. 2019 04; 13(4):381-397. PMID: 30761929.
      Citations: 6   Article has an altmetric score of 10    Fields:    Translation:HumansAnimals
    15. Wouters EFM, Franssen FM. Chronic Obstructive Pulmonary Disease: Shifting the Paradigm to the Vasculature. Am J Respir Crit Care Med. 2019 02 01; 199(3):258-259. PMID: 30265129.
      Citations: 3   Article has an altmetric score of 4    Fields:    Translation:Humans
    16. Houben CHM, Spruit MA, Luyten H, Pennings HJ, van den Boogaart VEM, Creemers JPHM, Wesseling G, Wouters EFM, Janssen DJA. Cluster-randomised trial of a nurse-led advance care planning session in patients with COPD and their loved ones. Thorax. 2019 04; 74(4):328-336. PMID: 30661022.
      Citations: 11   Article has an altmetric score of 49    Fields:    Translation:Humans
    17. Augustin IML, Wouters EFM, Houben-Wilke S, Gaffron S, Janssen DJA, Franssen FME, Spruit MA. Comprehensive Lung Function Assessment Does not Allow to Infer Response to Pulmonary Rehabilitation in Patients with COPD. J Clin Med. 2018 Dec 27; 8(1). PMID: 30591662.
      Citations: 6   Article has an altmetric score of 7    
    18. Watz H, Tetzlaff K, Magnussen H, Mueller A, Rodriguez-Roisin R, Wouters EFM, Vogelmeier C, Calverley PMA. Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM trial. Respir Res. 2018 Dec 13; 19(1):251. PMID: 30545350.
      Citations: 7   Article has an altmetric score of 29    Fields:    Translation:Humans
    19. Van Herck M, Spruit MA, Burtin C, Djamin R, Antons J, Goërtz YMJ, Ebadi Z, Janssen DJA, Vercoulen JH, Peters JB, Thong MSY, Otker J, Coors A, Sprangers MAG, Muris JWM, Wouters EFM, van 't Hul AJ. Fatigue is Highly Prevalent in Patients with Asthma and Contributes to the Burden of Disease. J Clin Med. 2018 Nov 23; 7(12). PMID: 30477110.
      Citations: 7   Article has an altmetric score of 13    
    20. Houben-Wilke S, Janssen DJA, Franssen FME, Vanfleteren LEGW, Wouters EFM, Spruit MA. Contribution of individual COPD assessment test (CAT) items to CAT total score and effects of pulmonary rehabilitation on CAT scores. Health Qual Life Outcomes. 2018 Oct 30; 16(1):205. PMID: 30376861.
      Citations: 11   Article has an altmetric score of 25    Fields:    Translation:Humans
    21. Oshagbemi OA, Franssen FME, Braeken DCW, Henskens Y, Wouters EFM, Maitland-van der Zee AH, Burden AM, de Vries F. Blood eosinophilia, use of inhaled corticosteroids, and risk of COPD exacerbations and mortality. Pharmacoepidemiol Drug Saf. 2018 11; 27(11):1191-1199. PMID: 30264901.
      Citations: 9   Article has an altmetric score of 1    Fields:    Translation:Humans
    22. Oshagbemi OA, Keene SJ, Driessen JHM, Jordan R, Wouters EFM, de Boer A, de Vries F, Franssen FME. Trends in moderate and severe exacerbations among COPD patients in the UK from 2005 to 2013. Respir Med. 2018 11; 144:1-6. PMID: 30366578.
      Citations: 2   Article has an altmetric score of 16    Fields:    Translation:Humans
    23. Augustin IML, Spruit MA, Houben-Wilke S, Franssen FME, Vanfleteren LEGW, Gaffron S, Janssen DJA, Wouters EFM. The respiratory physiome: Clustering based on a comprehensive lung function assessment in patients with COPD. PLoS One. 2018; 13(9):e0201593. PMID: 30208035.
      Citations: 13   Article has an altmetric score of 4    Fields:    Translation:Humans
    24. Nakken N, Spruit MA, van den Bogaart EHA, Crutzen R, Muris JWM, Wouters EFM, Janssen DJA. Identifying causes of perceptual differences in problematic activities of daily life between patients with COPD and proxies: A qualitative study. Aust Occup Ther J. 2019 02; 66(1):44-51. PMID: 30156291.
      Citations: 1   Article has an altmetric score of 12    Fields:    Translation:Humans
    25. Janssen R, de Brouwer B, von der Thüsen JH, Wouters EFM. Copper as the most likely pathogenic divergence factor between lung fibrosis and emphysema. Med Hypotheses. 2018 Nov; 120:49-54. PMID: 30220340.
      Citations: 5   Article has an altmetric score of 4    Fields:    Translation:HumansAnimalsCells
    26. Franssen FME, Smid DE, Deeg DJH, Huisman M, Poppelaars J, Wouters EFM, Spruit MA. The physical, mental, and social impact of COPD in a population-based sample: results from the Longitudinal Aging Study Amsterdam. NPJ Prim Care Respir Med. 2018 08 10; 28(1):30. PMID: 30097575.
      Citations: 13   Article has an altmetric score of 39    Fields:    Translation:Humans
    27. De Benedetto F, Pastorelli R, Ferrario M, de Blasio F, Marinari S, Brunelli L, Wouters EFM, Polverino F, Celli BR. Supplementation with Qter® and Creatine improves functional performance in COPD patients on long term oxygen therapy. Respir Med. 2018 09; 142:86-93. PMID: 30170808.
      Citations: 9   Article has an altmetric score of 14    Fields:    Translation:Humans
    28. Vaes AW, Spruit MA, Theunis J, Wouters EFM, De Boever P. Peripheral endothelial function is positively associated with maximal aerobic capacity in patients with chronic obstructive pulmonary disease. Respir Med. 2018 09; 142:41-47. PMID: 30170800.
      Citations: 3   Article has an altmetric score of 4    Fields:    Translation:HumansCells
    29. Verberkt CA, van den Beuken-van Everdingen MHJ, Schols JMGA, Datla S, Dirksen CD, Johnson MJ, van Kuijk SMJ, Wouters EFM, Janssen DJA. Adverse respiratory effects of opioids for chronic breathlessness: to what extent can we learn lessons from chronic pain? Eur Respir J. 2018 07; 52(1). PMID: 30026306.
      Citations: Article has an altmetric score of 1    Fields:    Translation:Humans
    30. Schumann DM, Leeming D, Papakonstantinou E, Blasi F, Kostikas K, Boersma W, Louis R, Milenkovic B, Aerts J, Sand JMB, Wouters EFM, Rohde G, Prat C, Torres A, Welte T, Tamm M, Karsdal M, Stolz D. Collagen Degradation and Formation Are Elevated in Exacerbated COPD Compared With Stable Disease. Chest. 2018 10; 154(4):798-807. PMID: 29966667.
      Citations: 7   Article has an altmetric score of 3    Fields:    Translation:Humans
    31. Alter P, Jörres RA, Watz H, Welte T, Gläser S, Schulz H, Bals R, Karch A, Wouters EFM, Vestbo J, Young D, Vogelmeier CF. Left ventricular volume and wall stress are linked to lung function impairment in COPD. Int J Cardiol. 2018 06 15; 261:172-178. PMID: 29657040.
      Citations: 5   Article has an altmetric score of 5    Fields:    Translation:Humans
    32. Houben-Wilke S, Augustin IM, Vercoulen JH, van Ranst D, Bij de Vaate E, Wempe JB, Spruit MA, Wouters EFM, Franssen FME. COPD stands for complex obstructive pulmonary disease. Eur Respir Rev. 2018 06 30; 27(148). PMID: 29875138.
      Citations: 9   Article has an altmetric score of 20    Fields:    Translation:Humans
    33. Stoilkova-Hartmann A, Franssen FME, Augustin IML, Wouters EFM, Barnard KD. COPD patient education and support - Achieving patient-centredness. Patient Educ Couns. 2018 11; 101(11):2031-2036. PMID: 29884533.
      Citations: 3   Article has an altmetric score of 4    Fields:    Translation:Humans
    34. Vaes AW, Spruit MA, Theunis J, Goswami N, Vanfleteren LE, Franssen FME, Wouters EFM, De Boever P. Looking into the eye of patients with chronic obstructive pulmonary disease: an opportunity for better microvascular profiling of these complex patients. Acta Ophthalmol. 2018 Sep; 96(6):539-549. PMID: 29770573.
      Citations: 6   Article has an altmetric score of 8    Fields:    Translation:Humans
    35. Benedikter BJ, Wouters EFM, Savelkoul PHM, Rohde GGU, Stassen FRM. Extracellular vesicles released in response to respiratory exposures: implications for chronic disease. J Toxicol Environ Health B Crit Rev. 2018; 21(3):142-160. PMID: 29714636.
      Citations: 16   Fields:    Translation:HumansCellsPHPublic Health
    36. Perkins TN, Peeters PM, Albrecht C, Schins RPF, Dentener MA, Mossman BT, Wouters EFM, Reynaert NL. Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells. Toxicol Appl Pharmacol. 2018 06 01; 348:43-53. PMID: 29673857.
      Citations: 2   Fields:    Translation:HumansAnimalsCells
    37. Goërtz YMJ, Looijmans M, Prins JB, Janssen DJA, Thong MSY, Peters JB, Burtin C, Meertens-Kerris Y, Coors A, Muris JWM, Sprangers MAG, Wouters EFM, Vercoulen JH, Spruit MA. Fatigue in patients with chronic obstructive pulmonary disease: protocol of the Dutch multicentre, longitudinal, observational FAntasTIGUE study. BMJ Open. 2018 04 10; 8(4):e021745. PMID: 29643168.
      Citations: 7   Article has an altmetric score of 7    Fields:    Translation:Humans
    38. McNamara RJ, Houben-Wilke S, Franssen FME, Smid DE, Vanfleteren LEGW, Groenen MTJ, Uszko-Lencer NHMK, Wouters EFM, Alison JA, Spruit MA. Determinants of functional, peak and endurance exercise capacity in people with chronic obstructive pulmonary disease. Respir Med. 2018 05; 138:81-87. PMID: 29724398.
      Citations: 5   Article has an altmetric score of 15    Fields:    Translation:Humans
    39. Wouters EFM, Wouters BBREF, Augustin IML, Houben-Wilke S, Vanfleteren LEGW, Franssen FME. Personalised pulmonary rehabilitation in COPD. Eur Respir Rev. 2018 Mar 31; 27(147). PMID: 29592864.
      Citations: 13   Article has an altmetric score of 58    Fields:    Translation:Humans
    40. Benedikter BJ, Weseler AR, Wouters EFM, Savelkoul PHM, Rohde GGU, Stassen FRM. Redox-dependent thiol modifications: implications for the release of extracellular vesicles. Cell Mol Life Sci. 2018 Jul; 75(13):2321-2337. PMID: 29594387.
      Citations: 13   Article has an altmetric score of 12    Fields:    Translation:HumansCells
    41. Celli BR, Locantore N, Tal-Singer R, Riley J, Miller B, Vestbo J, Yates JC, Silverman EK, Owen CA, Divo M, Pinto-Plata V, Wouters EFM, Faner R, Agusti A. Emphysema and extrapulmonary tissue loss in COPD: a multi-organ loss of tissue phenotype. Eur Respir J. 2018 02; 51(2). PMID: 29437944.
      Citations: 16   Article has an altmetric score of 21    Fields:    Translation:Humans
    42. Donner CF, Amaducci S, Bacci E, Baldacci S, Bartoli ML, Beghi GM, Benfante A, Brighindi S, Casali L, Castiglia D, Cazzola M, Celi A, Cianchetti S, Colombo G, Crimi C, Dente FL, Di Maria G, Di Maria A, Latorre M, Lavorini F, Maio S, Mannini C, Messina R, Paggiaro PL, Pignatti P, Price D, Scichilone N, Simoni M, Spanevello A, Stagno d'Alcontres M, Tan S, Torchio R, Viegi G, Visca D, Wouters EFM, Yu Hui Xin S. Inhalation therapy in the next decade: Determinants of adherence to treatment in asthma and COPD. Monaldi Arch Chest Dis. 2018 02 02; 88(1):886. PMID: 29557582.
      Citations: 2   Fields:    Translation:Humans
    43. Sprooten RTM, Lenaerts K, Braeken DCW, Grimbergen I, Rutten EP, Wouters EFM, Rohde GGU. Increased Small Intestinal Permeability during Severe Acute Exacerbations of COPD. Respiration. 2018; 95(5):334-342. PMID: 29393240.
      Citations: 10   Article has an altmetric score of 5    Fields:    Translation:Humans
    44. Liu WY, Spruit MA, Delbressine JM, Willems PJ, Franssen FME, Wouters EFM, Meijer K. Spatiotemporal gait characteristics in patients with COPD during the Gait Real-time Analysis Interactive Lab-based 6-minute walk test. PLoS One. 2017; 12(12):e0190099. PMID: 29284059.
      Citations: 4   Article has an altmetric score of 3    Fields:    Translation:Humans
    45. Buekers J, De Boever P, Vaes AW, Aerts JM, Wouters EFM, Spruit MA, Theunis J. Oxygen saturation measurements in telemonitoring of patients with COPD: a systematic review. Expert Rev Respir Med. 2018 02; 12(2):113-123. PMID: 29241369.
      Citations: 7   Article has an altmetric score of 12    Fields:    Translation:Humans
    46. McDonald MN, Diaz AA, Rutten E, Lutz SM, Harmouche R, San Jose Estepar R, Kinney G, Hokanson JE, Gower BA, Wouters EFM, Rennard SI, Hersh CP, Casaburi R, Dransfield MT, Silverman EK, Washko GR. Chest computed tomography-derived low fat-free mass index and mortality in COPD. Eur Respir J. 2017 Dec; 50(6). PMID: 29242259.
      Citations: 13   Article has an altmetric score of 15    Fields:    Translation:Humans
    47. Smid DE, Franssen FME, Gonik M, Miravitlles M, Casanova C, Cosio BG, de Lucas-Ramos P, Marin JM, Martinez C, Mir I, Soriano JB, de Torres JP, Agusti A, Atalay NB, Billington J, Boutou AK, Brighenti-Zogg S, Chaplin E, Coster S, Dodd JW, Dürr S, Fernandez-Villar A, Groenen MTJ, Guimarães M, Hejduk K, Higgins V, Hopkinson NS, Horita N, Houben-Wilke S, Janssen DJA, Jehn M, Joerres R, Karch A, Kelly JL, Kim YI, Kimura H, Koblizek V, Kocks JH, Kon SSC, Kwon N, Ladeira I, Lee SD, Leuppi JD, Locantore N, Lopez-Campos JL, D-C Man W, Maricic L, Mendoza L, Miedinger D, Mihaltan F, Minami S, van der Molen T, Murrells TJ, Nakken N, Nishijima Y, Norman IJ, Novotna B, O'Donnell DE, Ogata Y, Pereira ED, Piercy J, Price D, Pothirat C, Raghavan N, Ringbaek T, Sajkov D, Sigari N, Singh S, Small M, da Silva GF, Tanner RJ, Tsiligianni IG, Tulek B, Tzanakis N, Vanfleteren LEGW, Watz H, Webb KA, Wouters EFM, Xie GG, Yoshikawa M, Spruit MA. Redefining Cut-Points for High Symptom Burden of the Global Initiative for Chronic Obstructive Lung Disease Classification in 18,577 Patients With Chronic Obstructive Pulmonary Disease. J Am Med Dir Assoc. 2017 Dec 01; 18(12):1097.e11-1097.e24. PMID: 29169740.
      Citations: 14   Article has an altmetric score of 25    Fields:    Translation:Humans
    48. Piscaer I, Wouters EFM, Vermeer C, Janssens W, Franssen FME, Janssen R. Vitamin K deficiency: the linking pin between COPD and cardiovascular diseases? Respir Res. 2017 11 13; 18(1):189. PMID: 29132356.
      Citations: 3   Article has an altmetric score of 14    Fields:    Translation:HumansAnimals
    49. Benedikter BJ, Bouwman FG, Vajen T, Heinzmann ACA, Grauls G, Mariman EC, Wouters EFM, Savelkoul PH, Lopez-Iglesias C, Koenen RR, Rohde GGU, Stassen FRM. Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Sci Rep. 2017 11 10; 7(1):15297. PMID: 29127410.
      Citations: 59   Article has an altmetric score of 8    Fields:    Translation:HumansCells
    50. Qian X, Aboushousha R, van de Wetering C, Chia SB, Amiel E, Schneider RW, van der Velden JLJ, Lahue KG, Hoagland DA, Casey DT, Daphtary N, Ather JL, Randall MJ, Aliyeva M, Black KE, Chapman DG, Lundblad LKA, McMillan DH, Dixon AE, Anathy V, Irvin CG, Poynter ME, Wouters EFM, Vacek PM, Henket M, Schleich F, Louis R, van der Vliet A, Janssen-Heininger YMW. IL-1/inhibitory ?B kinase e-induced glycolysis augment epithelial effector function and promote allergic airways disease. J Allergy Clin Immunol. 2018 08; 142(2):435-450.e10. PMID: 29108965.
      Citations: 10   Article has an altmetric score of 4    Fields:    Translation:HumansAnimalsCells
    51. Wouters EFM. Obesity and Metabolic Abnormalities in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2017 Nov; 14(Supplement_5):S389-S394. PMID: 29161076.
      Citations: 9   Article has an altmetric score of 7    Fields:    Translation:Humans
    52. Calverley PMA, Tetzlaff K, Vogelmeier C, Fabbri LM, Magnussen H, Wouters EFM, Mezzanotte W, Disse B, Finnigan H, Asijee G, Hallmann C, Watz H. Eosinophilia, Frequent Exacerbations, and Steroid Response in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 11 01; 196(9):1219-1221. PMID: 28306321.
      Citations: 32   Article has an altmetric score of 6    Fields:    Translation:Humans
    53. Nakken N, Janssen DJA, van den Bogaart EHA, Muris JWM, Vercoulen JH, Custers FL, Bootsma GP, Gronenschild MHM, Wouters EFM, Spruit MA. Knowledge gaps in patients with COPD and their proxies. BMC Pulm Med. 2017 Oct 30; 17(1):136. PMID: 29084521.
      Citations: 8   Article has an altmetric score of 13    Fields:    Translation:Humans
    54. Vaes AW, Spruit MA, Theunis J, Goswami N, Vanfleteren LE, Franssen FME, Wouters EFM, De Boever P. Endothelial function in patients with chronic obstructive pulmonary disease: a systematic review of studies using flow mediated dilatation. Expert Rev Respir Med. 2017 12; 11(12):1021-1031. PMID: 28978239.
      Citations: 10   Article has an altmetric score of 9    Fields:    Translation:Humans
    55. Amaral AFS, Patel J, Kato BS, Obaseki DO, Lawin H, Tan WC, Juvekar SK, Harrabi I, Studnicka M, Wouters EFM, Loh LC, Bateman ED, Mortimer K, Buist AS, Burney PGJ. Airflow Obstruction and Use of Solid Fuels for Cooking or Heating: BOLD Results. Am J Respir Crit Care Med. 2018 03 01; 197(5):595-610. PMID: 28895752.
      Citations: 21   Article has an altmetric score of 30    Fields:    
    56. Koopman M, Vanfleteren LEGW, Steijns S, Wouters EFM, Sprooten R. Increased exercise tolerance using daytime mouthpiece ventilation for patients with diaphragm paralysis. Breathe (Sheff). 2017 Sep; 13(3):225-229. PMID: 28894483.
      Citations: 2   Article has an altmetric score of 13    
    57. Cleutjens FAHM, Spruit MA, Ponds RWHM, Vanfleteren LEGW, Franssen FME, Gijsen C, Dijkstra JB, Wouters EFM, Janssen DJA. Cognitive impairment and clinical characteristics in patients with chronic obstructive pulmonary disease. Chron Respir Dis. 2018 05; 15(2):91-102. PMID: 28553720.
      Citations: 7   Article has an altmetric score of 5    Fields:    Translation:Humans
    58. Donner CF, Carrozzi L, Maio S, Baldacci S, Pistelli F, Viegi G, Purro A, Torchio R, Clini E, Amaducci S, ZuWallack RL, Goldstein R, Morgan M, Bourbeau J, Vagheggini G, Wouters EFM. Integrating the care of the complex COPD patient. Monaldi Arch Chest Dis. 2017 05 18; 87(1):786. PMID: 28635207.
      Fields:    Translation:Humans
    59. Oshagbemi OA, Burden AM, Braeken DCW, Henskens Y, Wouters EFM, Driessen JHM, Maitland-van der Zee AH, de Vries F, Franssen FME. Stability of Blood Eosinophils in Patients with Chronic Obstructive Pulmonary Disease and in Control Subjects, and the Impact of Sex, Age, Smoking, and Baseline Counts. Am J Respir Crit Care Med. 2017 05 15; 195(10):1402-1404. PMID: 28165763.
      Citations: 34   Article has an altmetric score of 21    Fields:    Translation:HumansCells
    60. Spruit MA, Vercoulen JH, Sprangers MAG, Wouters EFM. Fatigue in COPD: an important yet ignored symptom. Lancet Respir Med. 2017 07; 5(7):542-544. PMID: 28438501.
      Citations: 13   Article has an altmetric score of 15    Fields:    Translation:Humans
    61. Mesquita R, Meijer K, Pitta F, Azcuna H, Goërtz YMJ, Essers JMN, Wouters EFM, Spruit MA. Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD. Respir Med. 2017 05; 126:122-129. PMID: 28427543.
      Citations: 14   Article has an altmetric score of 17    Fields:    Translation:Humans
    62. Cleutjens FAHM, Ponds RWHM, Spruit MA, Burgmans S, Jacobs HIL, Gronenschild EHBM, Staals J, Franssen FME, Dijkstra JB, Vanfleteren LEGW, Hofman PA, Wouters EFM, Janssen DJA. The Relationship between Cerebral Small Vessel Disease, Hippocampal Volume and Cognitive Functioning in Patients with COPD: An MRI Study. Front Aging Neurosci. 2017; 9:88. PMID: 28424613.
      Citations: 10   Article has an altmetric score of 9    
    63. Burtin C, Franssen FME, Vanfleteren LEGW, Groenen MTJ, Wouters EFM, Spruit MA. Lower-limb muscle function is a determinant of exercise tolerance after lung resection surgery in patients with lung cancer. Respirology. 2017 08; 22(6):1185-1189. PMID: 28370836.
      Citations: 8   Article has an altmetric score of 19    Fields:    Translation:Humans
    64. Benedikter BJ, Volgers C, van Eijck PH, Wouters EFM, Savelkoul PHM, Reynaert NL, Haenen GRMM, Rohde GGU, Weseler AR, Stassen FRM. Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants. Free Radic Biol Med. 2017 07; 108:334-344. PMID: 28359953.
      Citations: 21   Article has an altmetric score of 1    Fields:    Translation:HumansCells
    65. Eurlings IM, Reynaert NL, van de Wetering C, Aesif SW, Mercken EM, de Cabo R, van der Velden JL, Janssen-Heininger YM, Wouters EF, Dentener MA. Involvement of c-Jun N-Terminal Kinase in TNF-a-Driven Remodeling. Am J Respir Cell Mol Biol. 2017 03; 56(3):393-401. PMID: 27875656.
      Citations: 5   Article has an altmetric score of 2    Fields:    Translation:HumansAnimalsCells
    66. Uszko-Lencer NHMK, Mesquita R, Janssen E, Werter C, Brunner-La Rocca HP, Pitta F, Wouters EFM, Spruit MA. Reliability, construct validity and determinants of 6-minute walk test performance in patients with chronic heart failure. Int J Cardiol. 2017 Aug 01; 240:285-290. PMID: 28377186.
      Citations: 17   Article has an altmetric score of 10    Fields:    Translation:Humans
    67. Beijers RJHCG, van de Bool C, van den Borst B, Franssen FME, Wouters EFM, Schols AMWJ. Normal Weight but Low Muscle Mass and Abdominally Obese: Implications for the Cardiometabolic Risk Profile in Chronic Obstructive Pulmonary Disease. J Am Med Dir Assoc. 2017 Jun 01; 18(6):533-538. PMID: 28236608.
      Citations: 4   Article has an altmetric score of 4    Fields:    Translation:Humans
    68. Braeken DCW, Spruit MA, Houben-Wilke S, Smid DE, Rohde GGU, Wouters EFM, Franssen FME. Impact of exacerbations on adherence and outcomes of pulmonary rehabilitation in patients with COPD. Respirology. 2017 07; 22(5):942-949. PMID: 28139873.
      Citations: 2   Article has an altmetric score of 11    Fields:    Translation:Humans
    69. Cleutjens FAHM, Spruit MA, Ponds RWHM, Vanfleteren LEGW, Franssen FME, Dijkstra JB, Gijsen C, Wouters EFM, Janssen DJA. The Impact of Cognitive Impairment on Efficacy of Pulmonary Rehabilitation in Patients With COPD. J Am Med Dir Assoc. 2017 May 01; 18(5):420-426. PMID: 28108209.
      Citations: 9   Article has an altmetric score of 12    Fields:    Translation:Humans
    70. Houben-Wilke S, Jörres RA, Bals R, Franssen FM, Gläser S, Holle R, Karch A, Koch A, Magnussen H, Obst A, Schulz H, Spruit MA, Wacker ME, Welte T, Wouters EF, Vogelmeier C, Watz H. Peripheral Artery Disease and Its Clinical Relevance in Patients with Chronic Obstructive Pulmonary Disease in the COPD and Systemic Consequences-Comorbidities Network Study. Am J Respir Crit Care Med. 2017 01 15; 195(2):189-197. PMID: 27532739.
      Citations: 19   Article has an altmetric score of 40    Fields:    Translation:Humans
    71. Kahnert K, Lucke T, Biertz F, Lechner A, Watz H, Alter P, Bals R, Behr J, Holle R, Huber RM, Karrasch S, Stubbe B, Wacker M, Söhler S, Wouters EF, Vogelmeier C, Jörres RA. Transfer factor for carbon monoxide in patients with COPD and diabetes: results from the German COSYCONET cohort. Respir Res. 2017 01 13; 18(1):14. PMID: 28086884.
      Citations: 4   Article has an altmetric score of 1    Fields:    Translation:Humans
    72. Spina G, Spruit MA, Alison J, Benzo RP, Calverley PMA, Clarenbach CF, Costello RW, Donaire-Gonzalez D, Dürr S, Garcia-Aymerich J, van Gestel AJR, Gramm M, Hernandes NA, Hill K, Hopkinson NS, Jarreta D, Kohler M, Kirsten AM, Leuppi JD, Magnussen H, Maltais F, Man WD, McKeough ZJ, Mesquita R, Miedinger D, Pitta F, Singh SJ, Smeenk FWJM, Tal-Singer R, Vagaggini B, Waschki B, Watz H, Wouters EFM, Zogg S, den Brinker AC. Analysis of nocturnal actigraphic sleep measures in patients with COPD and their association with daytime physical activity. Thorax. 2017 08; 72(8):694-701. PMID: 28082529.
      Citations: 9   Article has an altmetric score of 48    Fields:    Translation:Humans
    73. Mesquita R, Nakken N, Janssen DJA, van den Bogaart EHA, Delbressine JML, Essers JMN, Meijer K, van Vliet M, de Vries GJ, Muris JWM, Pitta F, Wouters EFM, Spruit MA. Activity Levels and Exercise Motivation in Patients With COPD and Their Resident Loved Ones. Chest. 2017 05; 151(5):1028-1038. PMID: 28087303.
      Citations: 10   Article has an altmetric score of 28    Fields:    Translation:Humans
    74. Houben-Wilke S, Spruit MA, Uszko-Lencer NHMK, Otkinska G, Vanfleteren LEGW, Jones PW, Wouters EFM, Franssen FME. Echocardiographic abnormalities and their impact on health status in patients with COPD referred for pulmonary rehabilitation. Respirology. 2017 07; 22(5):928-934. PMID: 28001000.
      Citations: 8   Article has an altmetric score of 22    Fields:    Translation:Humans
    75. Houben CHM, Spruit MA, Schols JMGA, Wouters EFM, Janssen DJA. Instability of Willingness to Accept Life-Sustaining Treatments in Patients With Advanced Chronic Organ Failure During 1 Year. Chest. 2017 05; 151(5):1081-1087. PMID: 28007621.
      Citations: 3   Article has an altmetric score of 8    Fields:    Translation:Humans
    76. Bellinghausen C, Rohde GGU, Savelkoul PHM, Wouters EFM, Stassen FRM. Viral-bacterial interactions in the respiratory tract. J Gen Virol. 2016 Dec; 97(12):3089-3102. PMID: 27902340.
      Citations: 15   Article has an altmetric score of 14    Fields:    Translation:HumansAnimalsCells
    77. Nakken N, Janssen DJ, van den Bogaart EH, van Vliet M, de Vries GJ, Bootsma GP, Gronenschild MH, Delbressine JM, Muris JW, Wouters EF, Spruit MA. Patient versus proxy-reported problematic activities of daily life in patients with COPD. Respirology. 2017 02; 22(2):307-314. PMID: 27731530.
      Citations: 9   Article has an altmetric score of 5    Fields:    Translation:Humans
    78. Mesquita R, Franssen FM, Houben-Wilke S, Uszko-Lencer NH, Vanfleteren LE, Goërtz YM, Pitta F, Wouters EF, Spruit MA. What is the impact of impaired left ventricular ejection fraction in COPD after adjusting for confounders? Int J Cardiol. 2016 Dec 15; 225:365-370. PMID: 27760413.
      Citations: 3   Article has an altmetric score of 7    Fields:    Translation:Humans
    79. Cleutjens FA, Pedone C, Janssen DJ, Wouters EF, Incalzi RA. Sleep quality disturbances and cognitive functioning in elderly patients with COPD. ERJ Open Res. 2016 Jul; 2(3). PMID: 27957482.
      Citations: 1   Article has an altmetric score of 12    
    80. Smid DE, Franssen FM, Houben-Wilke S, Vanfleteren LE, Janssen DJ, Wouters EF, Spruit MA. Responsiveness and MCID Estimates for CAT, CCQ, and HADS in Patients With COPD Undergoing Pulmonary Rehabilitation: A Prospective Analysis. J Am Med Dir Assoc. 2017 01; 18(1):53-58. PMID: 27624705.
      Citations: 36   Article has an altmetric score of 19    Fields:    Translation:Humans
    81. Liu WY, Meijer K, Delbressine JM, Willems PJ, Franssen FM, Wouters EF, Spruit MA. Reproducibility and Validity of the 6-Minute Walk Test Using the Gait Real-Time Analysis Interactive Lab in Patients with COPD and Healthy Elderly. PLoS One. 2016; 11(9):e0162444. PMID: 27607426.
      Citations: 10   Article has an altmetric score of 13    Fields:    Translation:Humans
    82. Hoffman SM, Qian X, Nolin JD, Chapman DG, Chia SB, Lahue KG, Schneider R, Ather JL, Randall MJ, McMillan DH, Jones JT, Taatjes DJ, Aliyeva M, Daphtary N, Abdalla S, Lundblad LK, Ho YS, Anathy V, Irvin CG, Wouters EF, Reynaert NL, Dixon AE, van der Vliet A, Poynter ME, Janssen-Heininger YM. Ablation of Glutaredoxin-1 Modulates House Dust Mite-Induced Allergic Airways Disease in Mice. Am J Respir Cell Mol Biol. 2016 09; 55(3):377-86. PMID: 27035878.
      Citations: 12   Article has an altmetric score of 2    Fields:    Translation:AnimalsCells
    83. Franssen FM, Wouters EF, Vanfleteren LE. Indacaterol-Glycopyrronium for COPD. N Engl J Med. 2016 09 01; 375(9):898-9. PMID: 27579650.
      Fields:    Translation:Humans
    84. Stolz D, Leeming DJ, Kristensen JHE, Karsdal MA, Boersma W, Louis R, Milenkovic B, Kostikas K, Blasi F, Aerts J, Sand JMB, Wouters EFM, Rohde G, Prat C, Torres A, Welte T, Roth M, Papakonstantinou E, Tamm M. Systemic Biomarkers of Collagen and Elastin Turnover Are Associated With Clinically Relevant Outcomes in COPD. Chest. 2017 Jan; 151(1):47-59. PMID: 27575358.
      Citations: 17   Article has an altmetric score of 10    Fields:    Translation:HumansCells
    85. Andrianopoulos V, Celli BR, Franssen FM, Pinto-Plata VM, Calverley PM, Vanfleteren LE, Vogiatzis I, Vestbo J, Agusti A, Bakke PS, Rennard SI, MacNee W, Tal-Singer R, Yates JC, Wouters EF, Spruit MA. Determinants of exercise-induced oxygen desaturation including pulmonary emphysema in COPD: Results from the ECLIPSE study. Respir Med. 2016 10; 119:87-95. PMID: 27692154.
      Citations: 11   Article has an altmetric score of 14    Fields:    Translation:HumansCTClinical Trials
    86. Andrianopoulos V, Vanfleteren LE, Jarosch I, Gloeckl R, Schneeberger T, Wouters EF, Spruit MA, Kenn K. Transcutaneous carbon-dioxide partial pressure trends during six-minute walk test in patients with very severe COPD. Respir Physiol Neurobiol. 2016 11; 233:52-59. PMID: 27524634.
      Citations: 1   Article has an altmetric score of 2    Fields:    Translation:Humans
    87. Ubags ND, Burg E, Antkowiak M, Wallace AM, Dilli E, Bement J, Wargo MJ, Poynter ME, Wouters EF, Suratt BT. A Comparative Study of Lung Host Defense in Murine Obesity Models. Insights into Neutrophil Function. Am J Respir Cell Mol Biol. 2016 08; 55(2):188-200. PMID: 27128821.
      Citations: 18   Article has an altmetric score of 3    Fields:    Translation:AnimalsCells
    88. Smid DE, Spruit MA, Houben-Wilke S, Muris JWM, Rohde GGU, Wouters EFM, Franssen FME. Burden of COPD in patients treated in different care settings in the Netherlands. Respir Med. 2016 09; 118:76-83. PMID: 27578474.
      Citations: 9   Article has an altmetric score of 12    Fields:    Translation:Humans
    89. Reynaert NL, Gopal P, Rutten EPA, Wouters EFM, Schalkwijk CG. Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease. Int J Biochem Cell Biol. 2016 12; 81(Pt B):403-418. PMID: 27373680.
      Citations: 23   Article has an altmetric score of 3    Fields:    
    90. Ubags ND, Stapleton RD, Vernooy JH, Burg E, Bement J, Hayes CM, Ventrone S, Zabeau L, Tavernier J, Poynter ME, Parsons PE, Dixon AE, Wargo MJ, Littenberg B, Wouters EF, Suratt BT. Hyperleptinemia is associated with impaired pulmonary host defense. JCI Insight. 2016 Jun 02; 1(8). PMID: 27347561.
      Citations: 23   Article has an altmetric score of 7    Fields:    
    91. Vanfleteren LEGW, Spruit MA, Wouters EFM, Franssen FME. Management of chronic obstructive pulmonary disease beyond the lungs. Lancet Respir Med. 2016 11; 4(11):911-924. PMID: 27264777.
      Citations: 36   Article has an altmetric score of 45    Fields:    Translation:Humans
    92. Wouters EF, Augustin IM. COPD health-care delivery: a holistic and dynamic approach is needed. Lancet Respir Med. 2016 06; 4(6):e30-1. PMID: 27304801.
      Citations: 2   Article has an altmetric score of 7    Fields:    Translation:Humans
    93. Spruit MA, Burtin C, De Boever P, Langer D, Vogiatzis I, Wouters EF, Franssen FM. COPD and exercise: does it make a difference? Breathe (Sheff). 2016 Jun; 12(2):e38-49. PMID: 27408645.
      Citations: 8   Article has an altmetric score of 56    
    94. Joppa P, Tkacova R, Franssen FM, Hanson C, Rennard SI, Silverman EK, McDonald ML, Calverley PM, Tal-Singer R, Spruit MA, Kenn K, Wouters EF, Rutten EP. Sarcopenic Obesity, Functional Outcomes, and Systemic Inflammation in Patients With Chronic Obstructive Pulmonary Disease. J Am Med Dir Assoc. 2016 08 01; 17(8):712-8. PMID: 27161848.
      Citations: 15   Article has an altmetric score of 2    Fields:    Translation:Humans
    95. Perkins TN, Dentener MA, Stassen FR, Rohde GG, Mossman BT, Wouters EF, Reynaert NL. Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells. Toxicol Appl Pharmacol. 2016 06 15; 301:61-70. PMID: 27095093.
      Citations: 6   Fields:    Translation:HumansCells
    96. Watz H, Tetzlaff K, Wouters EF, Kirsten A, Magnussen H, Rodriguez-Roisin R, Vogelmeier C, Fabbri LM, Chanez P, Dahl R, Disse B, Finnigan H, Calverley PM. Blood eosinophil count and exacerbations in severe chronic obstructive pulmonary disease after withdrawal of inhaled corticosteroids: a post-hoc analysis of the WISDOM trial. Lancet Respir Med. 2016 05; 4(5):390-8. PMID: 27066739.
      Citations: 113   Article has an altmetric score of 112    Fields:    Translation:HumansCells
    97. Spruit MA, Franssen FM, Rutten EP, Wopereis S, Wouters EF, Vanfleteren LE. A new perspective on COPD exacerbations: monitoring impact by measuring physical, psychological and social resilience. Eur Respir J. 2016 Apr; 47(4):1024-7. PMID: 27037307.
      Citations: 5   Article has an altmetric score of 14    Fields:    Translation:Humans
    98. Karch A, Vogelmeier C, Welte T, Bals R, Kauczor HU, Biederer J, Heinrich J, Schulz H, Gläser S, Holle R, Watz H, Korn S, Adaskina N, Biertz F, Vogel C, Vestbo J, Wouters EF, Rabe KF, Söhler S, Koch A, Jörres RA. The German COPD cohort COSYCONET: Aims, methods and descriptive analysis of the study population at baseline. Respir Med. 2016 05; 114:27-37. PMID: 27109808.
      Citations: 37   Article has an altmetric score of 18    Fields:    Translation:Humans
    99. Hoffman SM, Nolin JD, Jones JT, Lahue KG, Chapman DG, Aliyeva M, Daphtary N, Lundblad LK, Abdalla S, Ather JL, Ho YS, Irvin CG, Anathy V, Wouters EF, Poynter ME, Janssen-Heininger YM. Ablation of the Thiol Transferase Glutaredoxin-1 Augments Protein S-Glutathionylation and Modulates Type 2 Inflammatory Responses and IL-17 in a House Dust Mite Model of Allergic Airway Disease in Mice. Ann Am Thorac Soc. 2016 Mar; 13 Suppl 1:S97. PMID: 27027965.
      Citations: 6   Article has an altmetric score of 2    Fields:    
    100. Jones PW, Watz H, Wouters EF, Cazzola M. COPD: the patient perspective. Int J Chron Obstruct Pulmon Dis. 2016; 11 Spec Iss:13-20. PMID: 26937186.
      Citations: 9   Article has an altmetric score of 4    Fields:    Translation:Humans
    101. Schleich FN, Dallinga JW, Henket M, Wouters EF, Louis R, Van Schooten FJ. Volatile organic compounds discriminate between eosinophilic and neutrophilic inflammation in vitro. J Breath Res. 2016 Feb 01; 10(1):016006. PMID: 26828318.
      Citations: 5   Article has an altmetric score of 8    Fields:    Translation:HumansCells
    102. Nakken N, Spruit MA, van den Bogaart EH, van Vliet M, de Vries GJ, Custers FL, Vercoulen JH, Asijee GM, Muris JW, Vanfleteren LE, Franssen FM, Wouters EF, Janssen DJ. Health Status and Morbidities in Resident Relatives of Patients With COPD. J Am Med Dir Assoc. 2016 Mar 01; 17(3):276.e1-8. PMID: 26805754.
      Citations: 4   Article has an altmetric score of 5    Fields:    Translation:Humans
    103. Rutten EP, Gopal P, Wouters EF, Franssen FM, Hageman GJ, Vanfleteren LE, Spruit MA, Reynaert NL. Various Mechanistic Pathways Representing the Aging Process Are Altered in COPD. Chest. 2016 Jan; 149(1):53-61. PMID: 26066545.
      Citations: 19   Article has an altmetric score of 16    Fields:    Translation:HumansCells
    104. Maatman RC, Spruit MA, van Melick PP, Peeters JP, Rutten EP, Vanfleteren LE, Wouters EF, Franssen FM. Effects of obesity on weight-bearing versus weight-supported exercise testing in patients with COPD. Respirology. 2016 Apr; 21(3):483-8. PMID: 26647921.
      Citations: 2   Article has an altmetric score of 14    Fields:    Translation:Humans
    105. Barnes PJ, Burney PG, Silverman EK, Celli BR, Vestbo J, Wedzicha JA, Wouters EF. Chronic obstructive pulmonary disease. Nat Rev Dis Primers. 2015 12 03; 1:15076. PMID: 27189863.
      Citations: 116   Article has an altmetric score of 121    Fields:    Translation:Humans
    106. Magnussen H, Tetzlaff K, Bateman ED, Watz H, Kirsten AM, Wouters EF, Disse B, Finnigan H, Rodriguez-Roisin R, Calverley PM. Lung function changes over time following withdrawal of inhaled corticosteroids in patients with severe COPD. Eur Respir J. 2016 Feb; 47(2):651-4. PMID: 26585433.
      Citations: 6   Article has an altmetric score of 7    Fields:    Translation:Humans
    107. Vanhove W, Peeters PM, Staelens D, Schraenen A, Van der Goten J, Cleynen I, De Schepper S, Van Lommel L, Reynaert NL, Schuit F, Van Assche G, Ferrante M, De Hertogh G, Wouters EF, Rutgeerts P, Vermeire S, Nys K, Arijs I. Strong Upregulation of AIM2 and IFI16 Inflammasomes in the Mucosa of Patients with Active Inflammatory Bowel Disease. Inflamm Bowel Dis. 2015 Nov; 21(11):2673-82. PMID: 26313692.
      Citations: 36   Article has an altmetric score of 9    Fields:    Translation:HumansCells
    108. Stoilkova-Hartmann A, Janssen DJ, Franssen FM, Wouters EF. Differences in change in coping styles between good responders, moderate responders and non-responders to pulmonary rehabilitation. Respir Med. 2015 Dec; 109(12):1540-5. PMID: 26603339.
      Citations: 1   Article has an altmetric score of 6    Fields:    Translation:Humans
    109. Spruit MA, Augustin IM, Vanfleteren LE, Janssen DJ, Gaffron S, Pennings HJ, Smeenk F, Pieters W, van den Bergh JJ, Michels AJ, Groenen MT, Rutten EP, Wouters EF, Franssen FM. Differential response to pulmonary rehabilitation in COPD: multidimensional profiling. Eur Respir J. 2015 Dec; 46(6):1625-35. PMID: 26453626.
      Citations: 39   Article has an altmetric score of 31    Fields:    Translation:Humans
    110. Rutten EP, Spruit MA, McDonald ML, Rennard S, Agusti A, Celli B, Miller BE, Crim C, Calverley PM, Hanson C, MacNee W, Franssen FM, Vanfleteren L, Wouters EF. Continuous fat-free mass decline in COPD: fact or fiction? Eur Respir J. 2015 Nov; 46(5):1496-8. PMID: 26381518.
      Citations: 6   Article has an altmetric score of 5    Fields:    Translation:Humans
    111. Triest FJ, Franssen FM, Spruit MA, Groenen MT, Wouters EF, Vanfleteren LE. Poor agreement between chart-based and objectively identified comorbidities of COPD. Eur Respir J. 2015 Nov; 46(5):1492-5. PMID: 26341984.
      Citations: 7   Article has an altmetric score of 6    Fields:    Translation:Humans
    112. Nakken N, Janssen DJ, van den Bogaart EH, Wouters EF, Franssen FM, Vercoulen JH, Spruit MA. Informal caregivers of patients with COPD: Home Sweet Home? Eur Respir Rev. 2015 Sep; 24(137):498-504. PMID: 26324811.
      Citations: 20   Article has an altmetric score of 16    Fields:    Translation:Humans
    113. Janssen DJ, Wouters EF, Spruit MA. Psychosocial consequences of living with breathlessness due to advanced disease. Curr Opin Support Palliat Care. 2015 Sep; 9(3):232-7. PMID: 26125305.
      Citations: 9   Article has an altmetric score of 9    Fields:    Translation:Humans
    114. Smid DE, Wilke S, Jones PW, Muris JW, Wouters EF, Franssen FM, Spruit MA. Impact of cardiovascular comorbidities on COPD Assessment Test (CAT) and its responsiveness to pulmonary rehabilitation in patients with moderate to very severe COPD: protocol of the Chance study. BMJ Open. 2015 Jul 21; 5(7):e007536. PMID: 26198426.
      Citations: 10   Fields:    Translation:Humans
    115. Vaes AW, Meijer K, Delbressine JM, Wiechert J, Willems P, Wouters EF, Franssen FM, Spruit MA. Efficacy of walking aids on self-paced outdoor walking in individuals with COPD: A randomized cross-over trial. Respirology. 2015 Aug; 20(6):932-9. PMID: 26150231.
      Citations: 2   Article has an altmetric score of 20    Fields:    Translation:Humans
    116. Vanfleteren LE, Franssen FM, Wouters EF, Spruit MA. COPD management: need for more consensus. Lancet Respir Med. 2015 Jul; 3(7):e21-2. PMID: 26170079.
      Citations: Article has an altmetric score of 1    Fields:    Translation:Humans
    117. Andrianopoulos V, Wouters EF, Pinto-Plata VM, Vanfleteren LE, Bakke PS, Franssen FM, Agusti A, MacNee W, Rennard SI, Tal-Singer R, Vogiatzis I, Vestbo J, Celli BR, Spruit MA. Prognostic value of variables derived from the six-minute walk test in patients with COPD: Results from the ECLIPSE study. Respir Med. 2015 Sep; 109(9):1138-46. PMID: 26143282.
      Citations: 28   Article has an altmetric score of 11    Fields:    Translation:Humans
    118. Mesquita R, Vanfleteren LE, Franssen FM, Sarv J, Taib Z, Groenen MT, Gaffron S, Bruijnzeel PL, Pitta F, Wouters EF, Spruit MA. Objectively identified comorbidities in COPD: impact on pulmonary rehabilitation outcomes. Eur Respir J. 2015 Aug; 46(2):545-8. PMID: 26113670.
      Citations: 9   Article has an altmetric score of 14    Fields:    Translation:Humans
    119. Sharma AS, Weerwind PW, Strauch U, van Belle A, Maessen JG, Wouters EF. Applying a low-flow CO2 removal device in severe acute hypercapnic respiratory failure. Perfusion. 2016 Mar; 31(2):149-55. PMID: 26040584.
      Citations: 2   Fields:    Translation:Humans
    120. Stoilkova-Hartmann A, Janssen DJ, Franssen FM, Spruit MA, Wouters EF. Attitudes of healthcare professionals providing pulmonary rehabilitation toward partnership in care. Heart Lung. 2015 Jul-Aug; 44(4):347-52. PMID: 26025762.
      Citations: 3   Article has an altmetric score of 3    Fields:    Translation:Humans
    121. Spina G, Casale P, Albert PS, Alison J, Garcia-Aymerich J, Costello RW, Hernandes NA, van Gestel AJ, Leuppi JD, Mesquita R, Singh SJ, Smeenk FW, Tal-Singer R, Wouters EF, Spruit MA, den Brinker AC. Identifying Physical Activity Profiles in COPD Patients Using Topic Models. IEEE J Biomed Health Inform. 2015 Sep; 19(5):1567-76. PMID: 25974957.
      Citations: 1   Article has an altmetric score of 3    Fields:    Translation:Humans
    122. Cleutjens F, Triest F, Wilke S, Vanfleteren LE, Franssen FM, Janssen DJ, Rutten EP, Spruit MA, Wouters EF. New insights in chronic obstructive pulmonary disease and comorbidity. Am J Respir Crit Care Med. 2015 05 01; 191(9):1081-2. PMID: 25932764.
      Fields:    
    123. van de Bool C, Rutten EP, Franssen FM, Wouters EF, Schols AM. Antagonistic implications of sarcopenia and abdominal obesity on physical performance in COPD. Eur Respir J. 2015 Aug; 46(2):336-45. PMID: 25882802.
      Citations: 13   Article has an altmetric score of 4    Fields:    Translation:Humans
    124. Wilke S, Jones PW, Müllerova H, Vestbo J, Tal-Singer R, Franssen FM, Agusti A, Bakke P, Calverley PM, Coxson HO, Crim C, Edwards LD, Lomas DA, MacNee W, Rennard SI, Yates JC, Wouters EF, Spruit MA. One-year change in health status and subsequent outcomes in COPD. Thorax. 2015 May; 70(5):420-5. PMID: 25782757.
      Citations: 22   Article has an altmetric score of 9    Fields:    Translation:Humans
    125. Andrianopoulos V, Holland AE, Singh SJ, Franssen FM, Pennings HJ, Michels AJ, Smeenk FW, Vogiatzis I, Wouters EF, Spruit MA. Six-minute walk distance in patients with chronic obstructive pulmonary disease: Which reference equations should we use? Chron Respir Dis. 2015 May; 12(2):111-9. PMID: 25754856.
      Citations: 6   Article has an altmetric score of 3    Fields:    Translation:Humans
    126. Romme EA, Geusens P, Lems WF, Rutten EP, Smeenk FW, van den Bergh JP, van Hal PT, Wouters EF. Fracture prevention in COPD patients; a clinical 5-step approach. Respir Res. 2015 Mar 07; 16:32. PMID: 25848824.
      Citations: 10   Fields:    Translation:Humans
    127. Rennard SI, Locantore N, Delafont B, Tal-Singer R, Silverman EK, Vestbo J, Miller BE, Bakke P, Celli B, Calverley PM, Coxson H, Crim C, Edwards LD, Lomas DA, MacNee W, Wouters EF, Yates JC, Coca I, Agustí A. Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Ann Am Thorac Soc. 2015 Mar; 12(3):303-12. PMID: 25642832.
      Citations: 43   Article has an altmetric score of 12    Fields:    Translation:Humans
    128. Nakken N, Spruit MA, Wouters EF, Schols JM, Janssen DJ. Family caregiving during 1-year follow-up in individuals with advanced chronic organ failure. Scand J Caring Sci. 2015 Dec; 29(4):734-44. PMID: 25648714.
      Citations: Article has an altmetric score of 1    Fields:    Translation:Humans
    129. Houben CH, Spruit MA, Schols JM, Wouters EF, Janssen DJ. Patient-Clinician Communication About End-of-Life Care in Patients With Advanced Chronic Organ Failure During One Year. J Pain Symptom Manage. 2015 Jun; 49(6):1109-15. PMID: 25623920.
      Citations: 6   Article has an altmetric score of 21    Fields:    Translation:Humans
    130. Engel M, Nowacki RM, Boden P, Reiss LK, Uhlig S, Reynaert NL, Gopal P, Wouters EF, Willems CH, Kloosterboer N, Wolfs TG, Zimmermann LJ, Vos GD, Kramer BW. The effects of dexamethasone and oxygen in ventilated adult sheep with early phase acute respiratory distress syndrome. Lung. 2015 Feb; 193(1):97-103. PMID: 25503749.
      Citations: 4   Article has an altmetric score of 1    Fields:    Translation:Animals
    131. Nakken N, Janssen DJ, van den Bogaart EH, Vercoulen JH, Wouters EF, Spruit MA. An observational, longitudinal study on the home environment of people with chronic obstructive pulmonary disease: the research protocol of the Home Sweet Home study. BMJ Open. 2014 Nov 10; 4(11):e006098. PMID: 25384686.
      Citations: 5   Fields:    Translation:Humans
    132. McDonald ML, Cho MH, Sørheim IC, Lutz SM, Castaldi PJ, Lomas DA, Coxson HO, Edwards LD, MacNee W, Vestbo J, Yates JC, Agusti A, Calverley PM, Celli B, Crim C, Rennard SI, Wouters EF, Bakke P, Tal-Singer R, Miller BE, Gulsvik A, Casaburi R, Wells JM, Regan EA, Make BJ, Hokanson JE, Lange C, Crapo JD, Beaty TH, Silverman EK, Hersh CP. Common genetic variants associated with resting oxygenation in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol. 2014 Nov; 51(5):678-87. PMID: 24825563.
      Citations: 12   Article has an altmetric score of 2    Fields:    Translation:HumansCellsCTClinical Trials
    133. Watz H, Pitta F, Rochester CL, Garcia-Aymerich J, ZuWallack R, Troosters T, Vaes AW, Puhan MA, Jehn M, Polkey MI, Vogiatzis I, Clini EM, Toth M, Gimeno-Santos E, Waschki B, Esteban C, Hayot M, Casaburi R, Porszasz J, McAuley E, Singh SJ, Langer D, Wouters EF, Magnussen H, Spruit MA. An official European Respiratory Society statement on physical activity in COPD. Eur Respir J. 2014 Dec; 44(6):1521-37. PMID: 25359358.
      Citations: 124   Article has an altmetric score of 27    Fields:    Translation:Humans
    134. Perkins TN, Peeters PM, Shukla A, Arijs I, Dragon J, Wouters EF, Reynaert NL, Mossman BT. Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells. Hum Mol Genet. 2015 Mar 01; 24(5):1374-89. PMID: 25351596.
      Citations: 4   Fields:    Translation:HumansCells
    135. Eurlings IM, Reynaert NL, van den Beucken T, Gosker HR, de Theije CC, Verhamme FM, Bracke KR, Wouters EF, Dentener MA. Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1a in mesenchymal transition. PLoS One. 2014; 9(10):e107757. PMID: 25329389.
      Citations: 19   Article has an altmetric score of 1    Fields:    Translation:HumansAnimalsCells
    136. Wilke S, Smid DE, Spruit MA, Janssen DJA, Muris JWM, van der Molen T, van den Akker M, Jones PW, Wouters EFM, Franssen FME. The 2014 Updated GOLD Strategy: A Comparison of the Various Scenarios. Chronic Obstr Pulm Dis. 2014 Sep 25; 1(2):212-220. PMID: 28848823.
      Citations: 1   
    137. Magnussen H, Disse B, Rodriguez-Roisin R, Kirsten A, Watz H, Tetzlaff K, Towse L, Finnigan H, Dahl R, Decramer M, Chanez P, Wouters EF, Calverley PM. Withdrawal of inhaled glucocorticoids and exacerbations of COPD. N Engl J Med. 2014 Oct 02; 371(14):1285-94. PMID: 25196117.
      Citations: 159   Article has an altmetric score of 176    Fields:    Translation:Humans
    138. Sillen MJ, Franssen FM, Vaes AW, Delbressine JM, Wouters EF, Spruit MA. Metabolic load during strength training or NMES in individuals with COPD: results from the DICES trial. BMC Pulm Med. 2014 Sep 02; 14:146. PMID: 25182377.
      Citations: 8   Article has an altmetric score of 2    Fields:    Translation:Humans
    139. Eurlings IM, Dentener MA, Mercken EM, de Cabo R, Bracke KR, Vernooy JH, Wouters EF, Reynaert NL. A comparative study of matrix remodeling in chronic models for COPD; mechanistic insights into the role of TNF-a. Am J Physiol Lung Cell Mol Physiol. 2014 Oct 01; 307(7):L557-65. PMID: 25106431.
      Citations: 13   Article has an altmetric score of 1    Fields:    Translation:AnimalsCells
    140. Janssen DJ, Müllerova H, Agusti A, Yates JC, Tal-Singer R, Rennard SI, Vestbo J, Wouters EF. Persistent systemic inflammation and symptoms of depression among patients with COPD in the ECLIPSE cohort. Respir Med. 2014 Nov; 108(11):1647-54. PMID: 25135745.
      Citations: 8   Fields:    Translation:Humans
    141. Hanson C, Rutten EP, Wouters EF, Rennard S. Influence of diet and obesity on COPD development and outcomes. Int J Chron Obstruct Pulmon Dis. 2014; 9:723-33. PMID: 25125974.
      Citations: 35   Article has an altmetric score of 2    Fields:    Translation:HumansAnimals
    142. Diaz AA, Zhou L, Young TP, McDonald ML, Harmouche R, Ross JC, San Jose Estepar R, Wouters EF, Coxson HO, MacNee W, Rennard S, Maltais F, Kinney GL, Hokanson JE, Washko GR. Chest CT measures of muscle and adipose tissue in COPD: gender-based differences in content and in relationships with blood biomarkers. Acad Radiol. 2014 Oct; 21(10):1255-61. PMID: 25088837.
      Citations: 17   Article has an altmetric score of 3    Fields:    Translation:Humans
    143. Vaes AW, Garcia-Aymerich J, Marott JL, Benet M, Groenen MT, Schnohr P, Franssen FM, Vestbo J, Wouters EF, Lange P, Spruit MA. Changes in physical activity and all-cause mortality in COPD. Eur Respir J. 2014 Nov; 44(5):1199-209. PMID: 25063247.
      Citations: 44   Article has an altmetric score of 30    Fields:    Translation:Humans
    144. Vanfleteren LE, Spruit MA, Wouters EF, Franssen FM. From the authors. Eur Respir J. 2014 Jul; 44(1):264-5. PMID: 24982056.
      Citations: Article has an altmetric score of 1    Fields:    Translation:Humans
    145. Breyer MK, Spruit MA, Hanson CK, Franssen FM, Vanfleteren LE, Groenen MT, Bruijnzeel PL, Wouters EF, Rutten EP. Prevalence of metabolic syndrome in COPD patients and its consequences. PLoS One. 2014; 9(6):e98013. PMID: 24950070.
      Citations: 25   Article has an altmetric score of 2    Fields:    Translation:Humans
    146. Sillen MJ, Franssen FM, Delbressine JM, Vaes AW, Wouters EF, Spruit MA. Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: response from the authors. Thorax. 2014 Oct; 69(10):953-4. PMID: 24928811.
      Citations: 3   Fields:    Translation:Humans
    147. Rutten EP, Spruit MA, Franssen FM, Buurman WA, Wouters EF, Lenaerts K. GI symptoms in patients with COPD. Chest. 2014 Jun; 145(6):1437-8. PMID: 24889455.
      Citations: 1   Fields:    Translation:Humans
    148. Andrianopoulos V, Wagers SS, Groenen MT, Vanfleteren LE, Franssen FM, Smeenk FW, Vogiatzis I, Wouters EF, Spruit MA. Characteristics and determinants of endurance cycle ergometry and six-minute walk distance in patients with COPD. BMC Pulm Med. 2014 May 31; 14:97. PMID: 24885117.
      Citations: 8   Article has an altmetric score of 7    Fields:    Translation:Humans
    149. Eurlings IM, Dentener MA, Cleutjens JP, Peutz CJ, Rohde GG, Wouters EF, Reynaert NL. Similar matrix alterations in alveolar and small airway walls of COPD patients. BMC Pulm Med. 2014 May 26; 14:90. PMID: 24886452.
      Citations: 24   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    150. Vestbo J, Agusti A, Wouters EF, Bakke P, Calverley PM, Celli B, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, MacNee W, Miller B, Rennard SI, Silverman EK, Yates JC, Tal-Singer R. Should we view chronic obstructive pulmonary disease differently after ECLIPSE? A clinical perspective from the study team. Am J Respir Crit Care Med. 2014 May 01; 189(9):1022-30. PMID: 24552242.
      Citations: 61   Article has an altmetric score of 3    Fields:    Translation:HumansCTClinical Trials
    151. Franssen FM, Rutten EP, Groenen MT, Vanfleteren LE, Wouters EF, Spruit MA. New reference values for body composition by bioelectrical impedance analysis in the general population: results from the UK Biobank. J Am Med Dir Assoc. 2014 Jun; 15(6):448.e1-6. PMID: 24755478.
      Citations: 38   Article has an altmetric score of 3    Fields:    Translation:Humans
    152. Vanfleteren LE, van Meerendonk AM, Franssen FM, Wouters EF, Mottaghy FM, van Kroonenburgh MJ, Bucerius J. A possible link between increased metabolic activity of fat tissue and aortic wall inflammation in subjects with COPD. A retrospective 18F-FDG-PET/CT pilot study. Respir Med. 2014 Jun; 108(6):883-90. PMID: 24785152.
      Citations: 9   Article has an altmetric score of 2    Fields:    Translation:Humans
    153. Wilke S, Spruit MA, Wouters EF, Schols JM, Franssen FM, Janssen DJ. Determinants of 1-year changes in disease-specific health status in patients with advanced chronic obstructive pulmonary disease: A 1-year observational study. Int J Nurs Pract. 2015 Jun; 21(3):239-48. PMID: 24666609.
      Citations: 6   Article has an altmetric score of 1    Fields:    Translation:Humans
    154. Cleutjens FA, Janssen DJ, Ponds RW, Dijkstra JB, Wouters EF. COgnitive-pulmonary disease. Biomed Res Int. 2014; 2014:697825. PMID: 24738069.
      Citations: 19   Article has an altmetric score of 2    Fields:    Translation:Humans
    155. Cleutjens FA, Wouters EF, Dijkstra JB, Spruit MA, Franssen FM, Vanfleteren LE, Ponds RW, Janssen DJ. The COgnitive-Pulmonary Disease (COgnitive-PD) study: protocol of a longitudinal observational comparative study on neuropsychological functioning of patients with COPD. BMJ Open. 2014 Mar 03; 4(3):e004495. PMID: 24589828.
      Citations: 7   Article has an altmetric score of 2    Fields:    Translation:Humans
    156. Houben CHM, Spruit MA, Groenen MTJ, Wouters EFM, Janssen DJA. Efficacy of advance care planning: a systematic review and meta-analysis. J Am Med Dir Assoc. 2014 Jul; 15(7):477-489. PMID: 24598477.
      Citations: 145   Article has an altmetric score of 39    Fields:    Translation:Humans
    157. Cleutjens FAHM, Spruit MA, Ponds RWHM, Dijkstra JB, Franssen FME, Wouters EFM, Janssen DJA. Cognitive functioning in obstructive lung disease: results from the United Kingdom biobank. J Am Med Dir Assoc. 2014 Mar; 15(3):214-219. PMID: 24513227.
      Citations: 9   Article has an altmetric score of 4    Fields:    Translation:Humans
    158. Gopal P, Reynaert NL, Scheijen JL, Schalkwijk CG, Franssen FM, Wouters EF, Rutten EP. Association of plasma sRAGE, but not esRAGE with lung function impairment in COPD. Respir Res. 2014 Feb 25; 15:24. PMID: 24564838.
      Citations: 19   Article has an altmetric score of 4    Fields:    Translation:Humans
    159. Ubags ND, Vernooy JH, Burg E, Hayes C, Bement J, Dilli E, Zabeau L, Abraham E, Poch KR, Nick JA, Dienz O, Zuñiga J, Wargo MJ, Mizgerd JP, Tavernier J, Rincón M, Poynter ME, Wouters EF, Suratt BT. The role of leptin in the development of pulmonary neutrophilia in infection and acute lung injury. Crit Care Med. 2014 Feb; 42(2):e143-51. PMID: 24231757.
      Citations: 21   Article has an altmetric score of 3    Fields:    Translation:HumansAnimalsCells
    160. Rutten EPA, Lenaerts K, Buurman WA, Wouters EFM. Disturbed intestinal integrity in patients with COPD: effects of activities of daily living. Chest. 2014 Feb; 145(2):245-252. PMID: 23928850.
      Citations: 36   Article has an altmetric score of 2    Fields:    Translation:HumansCells
    161. Op den Kamp CM, De Ruysscher DK, van den Heuvel M, Elferink M, Houben RM, Oberije CJ, Bootsma GP, Geraedts WH, Pitz CC, Langen RC, Wouters EF, Schols AM, Dingemans AM. Early body weight loss during concurrent chemo-radiotherapy for non-small cell lung cancer. J Cachexia Sarcopenia Muscle. 2014 Jun; 5(2):127-37. PMID: 24452446.
      Citations: 8   Fields:    
    162. Sillen MJ, Franssen FM, Delbressine JM, Vaes AW, Wouters EF, Spruit MA. Efficacy of lower-limb muscle training modalities in severely dyspnoeic individuals with COPD and quadriceps muscle weakness: results from the DICES trial. Thorax. 2014 Jun; 69(6):525-31. PMID: 24399630.
      Citations: 21   Article has an altmetric score of 19    Fields:    Translation:Humans
    163. Houben CH, Spruit MA, Wouters EF, Janssen DJ. A randomised controlled trial on the efficacy of advance care planning on the quality of end-of-life care and communication in patients with COPD: the research protocol. BMJ Open. 2014 Jan 02; 4(1):e004465. PMID: 24384905.
      Citations: 9   Article has an altmetric score of 8    Fields:    Translation:Humans
    164. Cesario A, Auffray C, Agusti A, Apolone G, Balling R, Barbanti P, Bellia A, Boccia S, Bousquet J, Cardaci V, Cazzola M, Dall'Armi V, Daraselia N, Ros LD, Bufalo AD, Ducci G, Ferri L, Fini M, Fossati C, Gensini G, Granone PM, Kinross J, Lauro D, Cascio GL, Lococo F, Lococo A, Maier D, Marcus F, Margaritora S, Marra C, Minati G, Neri M, Pasqua F, Pison C, Pristipino C, Roca J, Rosano G, Rossini PM, Russo P, Salinaro G, Shenhar S, Soreq H, Sterk PJ, Stocchi F, Torti M, Volterrani M, Wouters EF, Frustaci A, Bonassi S. A systems medicine clinical platform for understanding and managing non- communicable diseases. Curr Pharm Des. 2014; 20(38):5945-56. PMID: 24641232.
      Citations: 7   Fields:    Translation:Humans
    165. Agustí A, Barberà JA, Wouters EF, Peinado VI, Jeffery PK. Lungs, bone marrow, and adipose tissue. A network approach to the pathobiology of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013 Dec 15; 188(12):1396-406. PMID: 24175885.
      Citations: 8   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    166. Spruit MA, Pitta F, Garvey C, ZuWallack RL, Roberts CM, Collins EG, Goldstein R, McNamara R, Surpas P, Atsuyoshi K, López-Campos JL, Vogiatzis I, Williams JE, Lareau S, Brooks D, Troosters T, Singh SJ, Hartl S, Clini EM, Wouters EF. Differences in content and organisational aspects of pulmonary rehabilitation programmes. Eur Respir J. 2014 May; 43(5):1326-37. PMID: 24337043.
      Citations: 47   Article has an altmetric score of 14    Fields:    Translation:Humans
    167. Vanfleteren LE, Spruit MA, Groenen MT, Bruijnzeel PL, Taib Z, Rutten EP, Op 't Roodt J, Akkermans MA, Wouters EF, Franssen FM. Arterial stiffness in patients with COPD: the role of systemic inflammation and the effects of pulmonary rehabilitation. Eur Respir J. 2014 May; 43(5):1306-15. PMID: 24311762.
      Citations: 22   Article has an altmetric score of 8    Fields:    Translation:Humans
    168. Faner R, Tal-Singer R, Riley JH, Celli B, Vestbo J, MacNee W, Bakke P, Calverley PM, Coxson H, Crim C, Edwards LD, Locantore N, Lomas DA, Miller BE, Rennard SI, Wouters EF, Yates JC, Silverman EK, Agusti A. Lessons from ECLIPSE: a review of COPD biomarkers. Thorax. 2014 Jul; 69(7):666-72. PMID: 24310110.
      Citations: 52   Article has an altmetric score of 13    Fields:    Translation:Humans
    169. Janssen DJ, Schols JM, Wouters EF, Spruit MA. One-year stability of care dependency in patients with advanced chronic organ failure. J Am Med Dir Assoc. 2014 Feb; 15(2):127-32. PMID: 24314701.
      Citations: 3   Article has an altmetric score of 2    Fields:    Translation:Humans
    170. Romme EA, McAllister DA, Murchison JT, Van Beek EJ, Petrides GS, Price CO, Rutten EP, Smeenk FW, Wouters EF, MacNee W. Associations between COPD related manifestations: a cross-sectional study. Respir Res. 2013 Nov 19; 14:129. PMID: 24251912.
      Citations: 4   Article has an altmetric score of 8    Fields:    Translation:Humans
    171. Meis JJ, Bosma CB, Spruit MA, Franssen FM, Janssen DJ, Teixeira PJ, Augustin IM, Wouters EF, de Vries NK, Schols AM, Kremers SP. A qualitative assessment of COPD patients' experiences of pulmonary rehabilitation and guidance by healthcare professionals. Respir Med. 2014 Mar; 108(3):500-10. PMID: 24280544.
      Citations: 12   Article has an altmetric score of 13    Fields:    Translation:Humans
    172. Rutten EP, Calverley PM, Casaburi R, Agusti A, Bakke P, Celli B, Coxson HO, Crim C, Lomas DA, Macnee W, Miller BE, Rennard SI, Scanlon PD, Silverman EK, Tal-Singer R, Vestbo J, Watkins ML, Wouters EF. Changes in body composition in patients with chronic obstructive pulmonary disease: do they influence patient-related outcomes? Ann Nutr Metab. 2013; 63(3):239-47. PMID: 24216978.
      Citations: 19   Article has an altmetric score of 9    Fields:    Translation:Humans
    173. Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, Hill K, Holland AE, Lareau SC, Man WD, Pitta F, Sewell L, Raskin J, Bourbeau J, Crouch R, Franssen FM, Casaburi R, Vercoulen JH, Vogiatzis I, Gosselink R, Clini EM, Effing TW, Maltais F, van der Palen J, Troosters T, Janssen DJ, Collins E, Garcia-Aymerich J, Brooks D, Fahy BF, Puhan MA, Hoogendoorn M, Garrod R, Schols AM, Carlin B, Benzo R, Meek P, Morgan M, Rutten-van Mölken MP, Ries AL, Make B, Goldstein RS, Dowson CA, Brozek JL, Donner CF, Wouters EF. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):e13-64. PMID: 24127811.
      Citations: 661   Article has an altmetric score of 245    Fields:    Translation:Humans
    174. Cheng DT, Kim DK, Cockayne DA, Belousov A, Bitter H, Cho MH, Duvoix A, Edwards LD, Lomas DA, Miller BE, Reynaert N, Tal-Singer R, Wouters EF, Agustí A, Fabbri LM, Rames A, Visvanathan S, Rennard SI, Jones P, Parmar H, MacNee W, Wolff G, Silverman EK, Mayer RJ, Pillai SG. Systemic soluble receptor for advanced glycation endproducts is a biomarker of emphysema and associated with AGER genetic variants in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013 Oct 15; 188(8):948-57. PMID: 23947473.
      Citations: 68   Article has an altmetric score of 1    Fields:    Translation:Humans
    175. Hilmarsen CW, Wilke S, Engan H, Spruit MA, Rodenburg J, Janssen DJ, Steinshamn S, Jones PW, Wouters EF, Oldervoll L, Franssen FM. Impact of symptoms of anxiety and depression on COPD Assessment Test scores. Eur Respir J. 2014 Mar; 43(3):898-900. PMID: 24114965.
      Citations: 12   Article has an altmetric score of 3    Fields:    Translation:Humans
    176. Andrianopoulos V, Franssen FM, Peeters JP, Ubachs TJ, Bukari H, Groenen M, Burtin C, Vogiatzis I, Wouters EF, Spruit MA. Exercise-induced oxygen desaturation in COPD patients without resting hypoxemia. Respir Physiol Neurobiol. 2014 Jan 01; 190:40-6. PMID: 24121092.
      Citations: 19   Article has an altmetric score of 2    Fields:    Translation:Humans
    177. Romme EA, Rutten EP, Geusens P, de Jong JJ, van Rietbergen B, Smeenk FW, Wouters EF, van den Bergh JP. Bone stiffness and failure load are related with clinical parameters in men with chronic obstructive pulmonary disease. J Bone Miner Res. 2013 Oct; 28(10):2186-93. PMID: 23553944.
      Citations: 10   Article has an altmetric score of 1    Fields:    Translation:HumansCells
    178. Stoilkova A, Janssen DJ, Wouters EF. Educational programmes in COPD management interventions: a systematic review. Respir Med. 2013 Nov; 107(11):1637-50. PMID: 24012387.
      Citations: 14   Article has an altmetric score of 3    Fields:    Translation:Humans
    179. Sillen MJ, Franssen FM, Gosker HR, Wouters EF, Spruit MA. Metabolic and structural changes in lower-limb skeletal muscle following neuromuscular electrical stimulation: a systematic review. PLoS One. 2013; 8(9):e69391. PMID: 24019860.
      Citations: 16   Article has an altmetric score of 19    Fields:    Translation:Humans
    180. Lamprecht B, Vanfleteren LE, Studnicka M, Allison M, McBurnie MA, Vollmer WM, Tan WC, Nielsen R, Nastalek P, Gnatiuc L, Kaiser B, Janson C, Wouters EF, Burney P, Buist AS. Sex-related differences in respiratory symptoms: results from the BOLD Study. Eur Respir J. 2013 Sep; 42(3):858-60. PMID: 24000253.
      Citations: 12   Article has an altmetric score of 1    Fields:    Translation:Humans
    181. Wouters EF. Adiponectin: a novel link between adipose tissue and chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013 Sep 01; 188(5):522-3. PMID: 23992584.
      Citations: 2   Fields:    Translation:Humans
    182. Spruit MA, Sillen MJ, Groenen MT, Wouters EF, Franssen FM. New normative values for handgrip strength: results from the UK Biobank. J Am Med Dir Assoc. 2013 Oct; 14(10):775.e5-11. PMID: 23958225.
      Citations: 34   Article has an altmetric score of 5    Fields:    Translation:Humans
    183. Romme EA, Smeenk FW, Rutten EP, Wouters EF. Osteoporosis in chronic obstructive pulmonary disease. Expert Rev Respir Med. 2013 Aug; 7(4):397-410. PMID: 23952337.
      Citations: 20   Fields:    Translation:HumansAnimals
    184. Vaes AW, Cheung A, Atakhorrami M, Groenen MT, Amft O, Franssen FM, Wouters EF, Spruit MA. Effect of 'activity monitor-based' counseling on physical activity and health-related outcomes in patients with chronic diseases: A systematic review and meta-analysis. Ann Med. 2013 Sep; 45(5-6):397-412. PMID: 23952917.
      Citations: 35   Article has an altmetric score of 3    Fields:    Translation:Humans
    185. Berg I, Hanson C, Sayles H, Romberger D, Nelson A, Meza J, Miller B, Wouters EF, Macnee W, Rutten EP, Romme EA, Vestbo J, Edwards L, Rennard S. Vitamin D, vitamin D binding protein, lung function and structure in COPD. Respir Med. 2013 Oct; 107(10):1578-88. PMID: 23809536.
      Citations: 14   Article has an altmetric score of 18    Fields:    Translation:Humans
    186. Vanfleteren LE, Kocks JW, Stone IS, Breyer-Kohansal R, Greulich T, Lacedonia D, Buhl R, Fabbri LM, Pavord ID, Barnes N, Wouters EF, Agusti A. Moving from the Oslerian paradigm to the post-genomic era: are asthma and COPD outdated terms? Thorax. 2014 Jan; 69(1):72-9. PMID: 23794191.
      Citations: 13   Article has an altmetric score of 13    Fields:    Translation:Humans
    187. Stoilkova A, Wouters EF, Spruit MA, Franssen FM, Janssen DJ. The relationship between coping styles and clinical outcomes in patients with COPD entering pulmonary rehabilitation. COPD. 2013 Jun; 10(3):316-23. PMID: 23713594.
      Citations: 4   Article has an altmetric score of 2    Fields:    Translation:Humans
    188. Romme EA, Murchison JT, Edwards LD, van Beek E, Murchison DM, Rutten EP, Smeenk FW, Williams MC, Wouters EF, MacNee W. CT-measured bone attenuation in patients with chronic obstructive pulmonary disease: relation to clinical features and outcomes. J Bone Miner Res. 2013 Jun; 28(6):1369-77. PMID: 23361992.
      Citations: 22   Fields:    Translation:HumansCTClinical Trials
    189. Sillen MJ, Franssen FM, Delbressine JM, Uszko-Lencer NH, Vanfleteren LE, Rutten EP, Wouters EF, Spruit MA. Heterogeneity in clinical characteristics and co-morbidities in dyspneic individuals with COPD GOLD D: findings of the DICES trial. Respir Med. 2013 Aug; 107(8):1186-94. PMID: 23706780.
      Citations: 5   Fields:    Translation:HumansCTClinical Trials
    190. Hanson C, Rutten EP, Wouters EF, Rennard S. Diet and vitamin D as risk factors for lung impairment and COPD. Transl Res. 2013 Oct; 162(4):219-36. PMID: 23685188.
      Citations: 16   Article has an altmetric score of 16    Fields:    Translation:Humans
    191. Gopal P, Reynaert NL, Scheijen JL, Engelen L, Schalkwijk CG, Franssen FM, Wouters EF, Rutten EP. Plasma advanced glycation end-products and skin autofluorescence are increased in COPD. Eur Respir J. 2014 Feb; 43(2):430-8. PMID: 23645408.
      Citations: 23   Article has an altmetric score of 3    Fields:    Translation:Humans
    192. Mesquita R, Janssen DJ, Wouters EF, Schols JM, Pitta F, Spruit MA. Within-day test-retest reliability of the Timed Up & Go test in patients with advanced chronic organ failure. Arch Phys Med Rehabil. 2013 Nov; 94(11):2131-8. PMID: 23583345.
      Citations: 18   Article has an altmetric score of 4    Fields:    Translation:Humans
    193. Janssen DJ, Spruit MA, Schols JM, Wouters EF. Dynamic preferences for site of death among patients with advanced chronic obstructive pulmonary disease, chronic heart failure, or chronic renal failure. J Pain Symptom Manage. 2013 Dec; 46(6):826-36. PMID: 23571204.
      Citations: 7   Article has an altmetric score of 56    Fields:    Translation:Humans
    194. Cheung A, Janssen A, Amft O, Wouters EF, Spruit MA. Usability of digital media in patients with COPD: a pilot study. Int J Technol Assess Health Care. 2013 Apr; 29(2):162-5. PMID: 23552183.
      Citations: 2   Fields:    Translation:Humans
    195. Vanfleteren LE, Spruit MA, Groenen M, Gaffron S, van Empel VP, Bruijnzeel PL, Rutten EP, Op 't Roodt J, Wouters EF, Franssen FM. Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013 Apr 01; 187(7):728-35. PMID: 23392440.
      Citations: 211   Article has an altmetric score of 21    Fields:    Translation:Humans
    196. Stoilkova A, Janssen DJ, Franssen FM, Spruit MA, Wouters EF. Coping styles in patients with COPD before and after pulmonary rehabilitation. Respir Med. 2013 Jun; 107(6):825-33. PMID: 23541485.
      Citations: 6   Fields:    Translation:Humans
    197. Vernooy JH, Ubags ND, Brusselle GG, Tavernier J, Suratt BT, Joos GF, Wouters EF, Bracke KR. Leptin as regulator of pulmonary immune responses: involvement in respiratory diseases. Pulm Pharmacol Ther. 2013 Aug; 26(4):464-72. PMID: 23542720.
      Citations: 19   Article has an altmetric score of 4    Fields:    Translation:HumansAnimals
    198. Peeters PM, Perkins TN, Wouters EF, Mossman BT, Reynaert NL. Silica induces NLRP3 inflammasome activation in human lung epithelial cells. Part Fibre Toxicol. 2013 Feb 12; 10:3. PMID: 23402370.
      Citations: 48   Article has an altmetric score of 10    Fields:    Translation:HumansCells
    199. Kuipers I, Louis R, Manise M, Dentener MA, Irvin CG, Janssen-Heininger YM, Brightling CE, Wouters EF, Reynaert NL. Increased glutaredoxin-1 and decreased protein S-glutathionylation in sputum of asthmatics. Eur Respir J. 2013 Feb; 41(2):469-72. PMID: 23370801.
      Citations: 15   Article has an altmetric score of 1    Fields:    Translation:HumansCells
    200. Rutten EP, Franssen FM, Spruit MA, Wouters EF. Anemia is associated with bone mineral density in chronic obstructive pulmonary disease. COPD. 2013 Jun; 10(3):286-92. PMID: 23272661.
      Citations: 10   Fields:    Translation:Humans
    201. Sillen MJ, Vercoulen JH, van 't Hul AJ, Klijn PH, Wouters EF, van Ranst D, Peters JB, van Keimpema AR, Franssen FM, Otten HJ, Molema J, Jansen JJ, Spruit MA. The use of regression equations to estimate peak work rate in people with COPD -reply from the authors. COPD. 2013 Feb; 10(1):120-1. PMID: 23272669.
      Fields:    Translation:Humans
    202. Polkey MI, Spruit MA, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agustí A, Bakke PS, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, Miller BE, Crim C, Yates J, Wouters EF, Celli B. Six-minute-walk test in chronic obstructive pulmonary disease: minimal clinically important difference for death or hospitalization. Am J Respir Crit Care Med. 2013 Feb 15; 187(4):382-6. PMID: 23262518.
      Citations: 87   Article has an altmetric score of 24    Fields:    Translation:Humans
    203. Janssen DJ, Wouters EF, Schols JM, Spruit MA. Care dependency independently predicts two-year survival in outpatients with advanced chronic organ failure. J Am Med Dir Assoc. 2013 Mar; 14(3):194-8. PMID: 23141207.
      Citations: 6   Fields:    Translation:Humans
    204. Romme EA, Murchison JT, Phang KF, Jansen FH, Rutten EP, Wouters EF, Smeenk FW, Van Beek EJ, Macnee W. Bone attenuation on routine chest CT correlates with bone mineral density on DXA in patients with COPD. J Bone Miner Res. 2012 Nov; 27(11):2338-43. PMID: 22692725.
      Citations: 29   Article has an altmetric score of 1    Fields:    Translation:Humans
    205. Wouters EFM. Exploring the adipose tissue-lung interaction in COPD. Chest. 2012 Oct; 142(4):820-821. PMID: 23032446.
      Fields:    Translation:HumansAnimals
    206. Al-shair K, Muellerova H, Yorke J, Rennard SI, Wouters EF, Hanania NA, Sharafkhaneh A, Vestbo J. Examining fatigue in COPD: development, validity and reliability of a modified version of FACIT-F scale. Health Qual Life Outcomes. 2012 Aug 23; 10:100. PMID: 22913289.
      Citations: 8   Article has an altmetric score of 3    Fields:    Translation:Humans
    207. Wilke S, Janssen DJ, Wouters EF, Schols JM, Franssen FM, Spruit MA. Correlations between disease-specific and generic health status questionnaires in patients with advanced COPD: a one-year observational study. Health Qual Life Outcomes. 2012 Aug 21; 10:98. PMID: 22909154.
      Citations: 18   Article has an altmetric score of 1    Fields:    Translation:Humans
    208. Janssen DJ, Spruit MA, Schols JM, van der Sande FM, Frenken LA, Wouters EF. Insight into advance care planning for patients on dialysis. J Pain Symptom Manage. 2013 Jan; 45(1):104-13. PMID: 22841410.
      Citations: 13   Article has an altmetric score of 21    Fields:    Translation:HumansCells
    209. Vaes AW, Franssen FM, Meijer K, Cuijpers MW, Wouters EF, Rutten EP, Spruit MA. Effects of body mass index on task-related oxygen uptake and dyspnea during activities of daily life in COPD. PLoS One. 2012; 7(7):e41078. PMID: 22815922.
      Citations: 1   Article has an altmetric score of 1    Fields:    Translation:Humans
    210. Kuipers I, Bracke KR, Brusselle GG, Aesif SW, Krijgsman R, Arts IC, Wouters EF, Reynaert NL. Altered cigarette smoke-induced lung inflammation due to ablation of Grx1. PLoS One. 2012; 7(6):e38984. PMID: 22723915.
      Citations: 10   Fields:    Translation:AnimalsCells
    211. Breyer MK, Rutten EP, Locantore NW, Watkins ML, Miller BE, Wouters EF. Dysregulated adipokine metabolism in chronic obstructive pulmonary disease. Eur J Clin Invest. 2012 Sep; 42(9):983-91. PMID: 22703238.
      Citations: 17   Fields:    Translation:Humans
    212. van den Berge M, Hop WC, van der Molen T, van Noord JA, Creemers JP, Schreurs AJ, Wouters EF, Postma DS. Prediction and course of symptoms and lung function around an exacerbation in chronic obstructive pulmonary disease. Respir Res. 2012 Jun 06; 13:44. PMID: 22672621.
      Citations: 11   Article has an altmetric score of 5    Fields:    Translation:HumansCTClinical Trials
    213. Annegarn J, Spruit MA, Savelberg HH, Willems PJ, van de Bool C, Schols AM, Wouters EF, Meijer K. Differences in walking pattern during 6-min walk test between patients with COPD and healthy subjects. PLoS One. 2012; 7(5):e37329. PMID: 22624017.
      Citations: 25   Fields:    Translation:Humans
    214. Langen RC, Haegens A, Vernooy JH, Wouters EF, de Winther MP, Carlsen H, Steele C, Shoelson SE, Schols AM. NF-?B activation is required for the transition of pulmonary inflammation to muscle atrophy. Am J Respir Cell Mol Biol. 2012 Sep; 47(3):288-97. PMID: 22538866.
      Citations: 30   Fields:    Translation:AnimalsCells
    215. Engelen MP, Rutten EP, De Castro CL, Wouters EF, Schols AM, Deutz NE. Casein protein results in higher prandial and exercise induced whole body protein anabolism than whey protein in chronic obstructive pulmonary disease. Metabolism. 2012 Sep; 61(9):1289-300. PMID: 22512824.
      Citations: 9   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    216. Janssen DJ, Spruit MA, Wouters EF, Schols JM. Symptom distress in advanced chronic organ failure: disagreement among patients and family caregivers. J Palliat Med. 2012 Apr; 15(4):447-56. PMID: 22475192.
      Citations: 8   Fields:    Translation:Humans
    217. Romme EA, Rutten EP, Smeenk FW, Spruit MA, Menheere PP, Wouters EF. Vitamin D status is associated with bone mineral density and functional exercise capacity in patients with chronic obstructive pulmonary disease. Ann Med. 2013 Feb; 45(1):91-6. PMID: 22462562.
      Citations: 26   Article has an altmetric score of 4    Fields:    Translation:Humans
    218. Graat-Verboom L, Smeenk FW, van den Borne BE, Spruit MA, Donkers-van Rossum AB, Aarts RP, Wouters EF. Risk factors for osteoporosis in Caucasian patients with moderate chronic obstructive pulmonary disease: a case control study. Bone. 2012 Jun; 50(6):1234-9. PMID: 22426499.
      Citations: 19   Article has an altmetric score of 3    Fields:    Translation:Humans
    219. Spruit MA, Franssen FM, Rutten EP, Wagers SS, Wouters EF. Age-graded reductions in quadriceps muscle strength and peak aerobic capacity in COPD. Rev Bras Fisioter. 2012 Apr; 16(2):148-56. PMID: 22378475.
      Citations: 7   Article has an altmetric score of 4    Fields:    Translation:Humans
    220. Akkermans MA, Sillen MJ, Wouters EF, Spruit MA. Validation of the oxycon mobile metabolic system in healthy subjects. J Sports Sci Med. 2012; 11(1):182-3. PMID: 24137070.
      Citations: 5   Article has an altmetric score of 3    Fields:    
    221. Graat-Verboom L, Smeenk FW, van den Borne BE, Spruit MA, Jansen FH, van Enschot JW, Wouters EF. Progression of osteoporosis in patients with COPD: a 3-year follow up study. Respir Med. 2012 Jun; 106(6):861-70. PMID: 22369986.
      Citations: 26   Article has an altmetric score of 1    Fields:    Translation:Humans
    222. Sillen MJ, Vercoulen JH, van 't Hul AJ, Klijn PH, Wouters EF, van Ranst D, Peters JB, van Keimpema AR, Franssen FM, Otten HJ, Molema J, Jansen JJ, Spruit MA. Inaccuracy of estimating peak work rate from six-minute walk distance in patients with COPD. COPD. 2012 Jun; 9(3):281-8. PMID: 22360382.
      Citations: 1   Article has an altmetric score of 4    Fields:    Translation:Humans
    223. Vanfleteren LE, Franssen FM, Wesseling G, Wouters EF. The prevalence of chronic obstructive pulmonary disease in Maastricht, the Netherlands. Respir Med. 2012 Jun; 106(6):871-4. PMID: 22349067.
      Citations: 14   Article has an altmetric score of 3    Fields:    Translation:Humans
    224. Perkins TN, Shukla A, Peeters PM, Steinbacher JL, Landry CC, Lathrop SA, Steele C, Reynaert NL, Wouters EF, Mossman BT. Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells. Part Fibre Toxicol. 2012 Feb 02; 9(1):6. PMID: 22300531.
      Citations: 21   Fields:    Translation:HumansCells
    225. Gopal P, Rutten EP, Dentener MA, Wouters EF, Reynaert NL. Decreased plasma sRAGE levels in COPD: influence of oxygen therapy. Eur J Clin Invest. 2012 Aug; 42(8):807-14. PMID: 22288943.
      Citations: 11   Article has an altmetric score of 1    Fields:    Translation:Humans
    226. Kuipers I, Bracke KR, Brusselle GG, Wouters EF, Reynaert NL. Smoke decreases reversible oxidations S-glutathionylation and S-nitrosylation in mice. Free Radic Res. 2012 Feb; 46(2):164-73. PMID: 22145974.
      Citations: 7   Article has an altmetric score of 1    Fields:    Translation:AnimalsCells
    227. Vanfleteren LE, Franssen FM, Uszko-Lencer NH, Spruit MA, Celis M, Gorgels AP, Wouters EF. Frequency and relevance of ischemic electrocardiographic findings in patients with chronic obstructive pulmonary disease. Am J Cardiol. 2011 Dec 01; 108(11):1669-74. PMID: 22077976.
      Citations: 8   Article has an altmetric score of 7    Fields:    Translation:Humans
    228. Waschki B, Spruit MA, Watz H, Albert PS, Shrikrishna D, Groenen M, Smith C, Man WD, Tal-Singer R, Edwards LD, Calverley PM, Magnussen H, Polkey MI, Wouters EF. Physical activity monitoring in COPD: compliance and associations with clinical characteristics in a multicenter study. Respir Med. 2012 Apr; 106(4):522-30. PMID: 22118987.
      Citations: 44   Article has an altmetric score of 3    Fields:    Translation:Humans
    229. Vaes AW, Annegarn J, Meijer K, Cuijpers MWJ, Franssen FME, Wiechert J, Wouters EFM, Spruit MA. The effects of a "new" walking aid on exercise performance in patients with COPD: a randomized crossover trial. Chest. 2012 May; 141(5):1224-1232. PMID: 22116797.
      Citations: 5   Article has an altmetric score of 13    Fields:    Translation:Humans
    230. Annegarn J, Spruit MA, Uszko-Lencer NH, Vanbelle S, Savelberg HH, Schols AM, Wouters EF, Meijer K. Objective physical activity assessment in patients with chronic organ failure: a validation study of a new single-unit activity monitor. Arch Phys Med Rehabil. 2011 Nov; 92(11):1852-1857.e1. PMID: 22032218.
      Citations: 18   Article has an altmetric score of 3    Fields:    Translation:Humans
    231. Janssen DJA, Spruit MA, Schols JMGA, Cox B, Nawrot TS, Curtis JR, Wouters EFM. Predicting changes in preferences for life-sustaining treatment among patients with advanced chronic organ failure. Chest. 2012 May; 141(5):1251-1259. PMID: 22016488.
      Citations: 22   Article has an altmetric score of 14    Fields:    Translation:Humans
    232. Franssen FM, Spruit MA, Wouters EF. Determinants of polypharmacy and compliance with GOLD guidelines in patients with chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2011; 6:493-501. PMID: 22069360.
      Citations: 29   Article has an altmetric score of 10    Fields:    Translation:Humans
    233. Vogelmeier CF, Wouters EF. Treating the systemic effects of chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2011 Aug; 8(4):376-9. PMID: 21816995.
      Citations: 3   Fields:    Translation:Humans
    234. Wouters EFM, Franssen FME, Spruit MA. Survival and physical activity in COPD: a giant leap forward! Chest. 2011 Aug; 140(2):279-281. PMID: 21813522.
      Citations: Article has an altmetric score of 3    Fields:    Translation:Humans
    235. Spruit MA, Polkey MI, Celli B, Edwards LD, Watkins ML, Pinto-Plata V, Vestbo J, Calverley PM, Tal-Singer R, Agusti A, Coxson HO, Lomas DA, MacNee W, Rennard S, Silverman EK, Crim CC, Yates J, Wouters EF. Predicting outcomes from 6-minute walk distance in chronic obstructive pulmonary disease. J Am Med Dir Assoc. 2012 Mar; 13(3):291-7. PMID: 21778120.
      Citations: 67   Article has an altmetric score of 6    Fields:    Translation:Humans
    236. Aesif SW, Kuipers I, van der Velden J, Tully JE, Guala AS, Anathy V, Sheely JI, Reynaert NL, Wouters EF, van der Vliet A, Janssen-Heininger YM. Activation of the glutaredoxin-1 gene by nuclear factor ?B enhances signaling. Free Radic Biol Med. 2011 Sep 15; 51(6):1249-57. PMID: 21762778.
      Citations: 26   Fields:    Translation:AnimalsCellsPHPublic Health
    237. Janssen DJ, Spruit MA, Wouters EF, Schols JM. Family caregiving in advanced chronic organ failure. J Am Med Dir Assoc. 2012 May; 13(4):394-9. PMID: 21621478.
      Citations: 9   Article has an altmetric score of 1    Fields:    Translation:Humans
    238. Janssen DJ, Spruit MA, Uszko-Lencer NH, Schols JM, Wouters EF. Symptoms, comorbidities, and health care in advanced chronic obstructive pulmonary disease or chronic heart failure. J Palliat Med. 2011 Jun; 14(6):735-43. PMID: 21510771.
      Citations: 47   Article has an altmetric score of 6    Fields:    Translation:Humans
    239. Kuipers I, Guala AS, Aesif SW, Konings G, Bouwman FG, Mariman EC, Wouters EF, Janssen-Heininger YM, Reynaert NL. Cigarette smoke targets glutaredoxin 1, increasing s-glutathionylation and epithelial cell death. Am J Respir Cell Mol Biol. 2011 Nov; 45(5):931-7. PMID: 21454804.
      Citations: 10   Fields:    Translation:HumansAnimalsCells
    240. Janssen DJ, Franssen FM, Wouters EF, Schols JM, Spruit MA. Impaired health status and care dependency in patients with advanced COPD or chronic heart failure. Qual Life Res. 2011 Dec; 20(10):1679-88. PMID: 21442430.
      Citations: 15   Article has an altmetric score of 3    Fields:    Translation:Humans
    241. Vaes AW, Wouters EFM, Franssen FME, Uszko-Lencer NHMK, Stakenborg KHP, Westra M, Meijer K, Schols AMWJ, Janssen PP, Spruit MA. Task-related oxygen uptake during domestic activities of daily life in patients with COPD and healthy elderly subjects. Chest. 2011 Oct; 140(4):970-979. PMID: 21415128.
      Citations: 18   Article has an altmetric score of 3    Fields:    Translation:Humans
    242. Breyer MK, Rutten EP, Vernooy JH, Spruit MA, Dentener MA, van der Kallen C, vanGreevenbroek MM, Wouters EF. Gender differences in the adipose secretome system in chronic obstructive pulmonary disease (COPD): a pivotal role of leptin. Respir Med. 2011 Jul; 105(7):1046-53. PMID: 21367591.
      Citations: 21   Fields:    Translation:Humans
    243. Graat-Verboom L, van den Borne BE, Smeenk FW, Spruit MA, Wouters EF. Osteoporosis in COPD outpatients based on bone mineral density and vertebral fractures. J Bone Miner Res. 2011 Mar; 26(3):561-8. PMID: 20878771.
      Citations: 34   Article has an altmetric score of 3    Fields:    Translation:Humans
    244. Annegarn J, Meijer K, Passos VL, Stute K, Wiechert J, Savelberg HH, Schols AM, Wouters EF, Spruit MA. Problematic activities of daily life are weakly associated with clinical characteristics in COPD. J Am Med Dir Assoc. 2012 Mar; 13(3):284-90. PMID: 21450242.
      Citations: 26   Article has an altmetric score of 3    Fields:    Translation:Humans
    245. Janssen DJ, Engelberg RA, Wouters EF, Curtis JR. Advance care planning for patients with COPD: past, present and future. Patient Educ Couns. 2012 Jan; 86(1):19-24. PMID: 21316899.
      Citations: 16   Article has an altmetric score of 6    Fields:    Translation:Humans
    246. Rutten EP, Grydeland TB, Pillai SG, Wagers S, Dirksen A, Coxson HO, Gulsvik A, Wouters EF, Bakke PS. Quantitative CT: Associations between Emphysema, Airway Wall Thickness and Body Composition in COPD. Pulm Med. 2011; 2011:419328. PMID: 21647214.
      Citations: 16   Fields:    
    247. Spruit MA, Wouters EF, Eterman RM, Meijer K, Wagers SS, Stakenborg KH, Uszko-Lencer NH. Task-related oxygen uptake and symptoms during activities of daily life in CHF patients and healthy subjects. Eur J Appl Physiol. 2011 Aug; 111(8):1679-86. PMID: 21210281.
      Citations: 7   Fields:    Translation:Humans
    248. Sillen MJ, Wouters EF, Franssen FM, Meijer K, Stakenborg KH, Spruit MA. Oxygen uptake, ventilation, and symptoms during low-frequency versus high-frequency NMES in COPD: a pilot study. Lung. 2011 Feb; 189(1):21-6. PMID: 21080183.
      Citations: 11   Article has an altmetric score of 4    Fields:    Translation:Humans
    249. Franssen FM, Sauerwein HP, Ackermans MT, Rutten EP, Wouters EF, Schols AM. Increased postabsorptive and exercise-induced whole-body glucose production in patients with chronic obstructive pulmonary disease. Metabolism. 2011 Jul; 60(7):957-64. PMID: 21056887.
      Citations: 7   Fields:    Translation:HumansCells
    250. Hanania NA, Müllerova H, Locantore NW, Vestbo J, Watkins ML, Wouters EF, Rennard SI, Sharafkhaneh A. Determinants of depression in the ECLIPSE chronic obstructive pulmonary disease cohort. Am J Respir Crit Care Med. 2011 Mar 01; 183(5):604-11. PMID: 20889909.
      Citations: 81   Article has an altmetric score of 17    Fields:    Translation:Humans
    251. Hurst JR, Vestbo J, Anzueto A, Locantore N, Müllerova H, Tal-Singer R, Miller B, Lomas DA, Agusti A, Macnee W, Calverley P, Rennard S, Wouters EF, Wedzicha JA. Susceptibility to exacerbation in chronic obstructive pulmonary disease. N Engl J Med. 2010 Sep 16; 363(12):1128-38. PMID: 20843247.
      Citations: 842   Article has an altmetric score of 76    Fields:    Translation:Humans
    252. Janssen DJA, Spruit MA, Schols JMGA, Wouters EFM. A call for high-quality advance care planning in outpatients with severe COPD or chronic heart failure. Chest. 2011 May; 139(5):1081-1088. PMID: 20829337.
      Citations: 30   Article has an altmetric score of 48    Fields:    Translation:Humans
    253. Breyer MK, Breyer-Kohansal R, Funk GC, Dornhofer N, Spruit MA, Wouters EF, Burghuber OC, Hartl S. Nordic walking improves daily physical activities in COPD: a randomised controlled trial. Respir Res. 2010 Aug 22; 11:112. PMID: 20727209.
      Citations: 28   Article has an altmetric score of 21    Fields:    Translation:Humans
    254. Janssen DJ, Spruit MA, Leue C, Gijsen C, Hameleers H, Schols JM, Wouters EF. Symptoms of anxiety and depression in COPD patients entering pulmonary rehabilitation. Chron Respir Dis. 2010 Aug; 7(3):147-57. PMID: 20688892.
      Citations: 34   Article has an altmetric score of 3    Fields:    Translation:Humans
    255. Sørheim IC, Bakke P, Gulsvik A, Pillai SG, Johannessen A, Gaarder PI, Campbell EJ, Agustí A, Calverley PM, Donner CF, Make BJ, Rennard SI, Vestbo J, Wouters EF, Paré PD, Levy RD, Coxson HO, Lomas DA, Hersh CP, Silverman EK. a1-Antitrypsin protease inhibitor MZ heterozygosity is associated with airflow obstruction in two large cohorts. Chest. 2010 Nov; 138(5):1125-32. PMID: 20595457.
      Citations: 27   Article has an altmetric score of 9    Fields:    Translation:Humans
    256. Han MK, Agusti A, Calverley PM, Celli BR, Criner G, Curtis JL, Fabbri LM, Goldin JG, Jones PW, Macnee W, Make BJ, Rabe KF, Rennard SI, Sciurba FC, Silverman EK, Vestbo J, Washko GR, Wouters EF, Martinez FJ. Chronic obstructive pulmonary disease phenotypes: the future of COPD. Am J Respir Crit Care Med. 2010 Sep 01; 182(5):598-604. PMID: 20522794.
      Citations: 300   Article has an altmetric score of 23    Fields:    Translation:Humans
    257. Rutten EP, Breyer MK, Spruit MA, Hofstra T, van Melick PP, Schols AM, Wouters EF. Abdominal fat mass contributes to the systemic inflammation in chronic obstructive pulmonary disease. Clin Nutr. 2010 Dec; 29(6):756-60. PMID: 20566396.
      Citations: 12   Article has an altmetric score of 3    Fields:    Translation:Humans
    258. Vernooy JH, Bracke KR, Drummen NE, Pauwels NS, Zabeau L, van Suylen RJ, Tavernier J, Joos GF, Wouters EF, Brusselle GG. Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice. J Immunol. 2010 Jun 15; 184(12):7169-77. PMID: 20488786.
      Citations: 22   Article has an altmetric score of 4    Fields:    Translation:AnimalsPHPublic Health
    259. Spruit MA, Watkins ML, Edwards LD, Vestbo J, Calverley PM, Pinto-Plata V, Celli BR, Tal-Singer R, Wouters EF. Determinants of poor 6-min walking distance in patients with COPD: the ECLIPSE cohort. Respir Med. 2010 Jun; 104(6):849-57. PMID: 20471236.
      Citations: 60   Article has an altmetric score of 3    Fields:    Translation:Humans
    260. Hersh CP, Pillai SG, Zhu G, Lomas DA, Bakke P, Gulsvik A, DeMeo DL, Klanderman BJ, Lazarus R, Litonjua AA, Sparrow D, Reilly JJ, Agusti A, Calverley PM, Donner CF, Levy RD, Make BJ, Paré PD, Rennard SI, Vestbo J, Wouters EF, Scholand MB, Coon H, Hoidal J, Silverman EK. Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene. Am J Respir Crit Care Med. 2010 Sep 01; 182(5):605-13. PMID: 20463177.
      Citations: 15   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    261. Janssen DJ, Spruit MA, Alsemgeest TP, Does JD, Schols JM, Wouters EF. A patient-centred interdisciplinary palliative care programme for end-stage chronic respiratory diseases. Int J Palliat Nurs. 2010 Apr; 16(4):189-94. PMID: 20559181.
      Citations: 2   Article has an altmetric score of 3    Fields:    Translation:Humans
    262. Graat-Verboom L, Spruit MA, van den Borne BE, Smeenk FW, Wouters EF. Whole-Body versus Local DXA-Scan for the Diagnosis of Osteoporosis in COPD Patients. J Osteoporos. 2010 Feb 07; 2010:640878. PMID: 20976078.
      Citations: 10   
    263. Geraets L, Haegens A, Weseler AR, Brauers K, Vernooy JH, Wouters EF, Bast A, Hageman GJ. Inhibition of acute pulmonary and systemic inflammation by 1,7-dimethylxanthine. Eur J Pharmacol. 2010 Mar 10; 629(1-3):132-9. PMID: 19962977.
      Citations: 4   Fields:    Translation:HumansAnimalsCells
    264. Van Schayck CP, Kaper J, Wagena EJ, Wouters EF, Severens JL. The cost-effectiveness of antidepressants for smoking cessation in chronic obstructive pulmonary disease (COPD) patients. Addiction. 2009 Dec; 104(12):2110-7. PMID: 19922576.
      Citations: 6   Fields:    Translation:Humans
    265. Wouters EF, Reynaert NL, Dentener MA, Vernooy JH. Systemic and local inflammation in asthma and chronic obstructive pulmonary disease: is there a connection? Proc Am Thorac Soc. 2009 Dec; 6(8):638-47. PMID: 20008867.
      Citations: 38   Fields:    Translation:Humans
    266. Chavannes NH, Schermer TR, Wouters EF, Akkermans RP, Dekhuijzen RP, Muris JW, van Weel C, van Schayck OC. Predictive value and utility of oral steroid testing for treatment of COPD in primary care: the COOPT study. Int J Chron Obstruct Pulmon Dis. 2009; 4:431-6. PMID: 20037682.
      Citations: 3   Fields:    Translation:Humans
    267. Wouters EF, Vanderhoven IM. Pulmonary rehabilitation and integrated care. Semin Respir Crit Care Med. 2009 Dec; 30(6):713-20. PMID: 19941229.
      Fields:    Translation:Humans
    268. Güngör N, Haegens A, Knaapen AM, Godschalk RW, Chiu RK, Wouters EF, van Schooten FJ. Lung inflammation is associated with reduced pulmonary nucleotide excision repair in vivo. Mutagenesis. 2010 Jan; 25(1):77-82. PMID: 19917589.
      Citations: 17   Fields:    Translation:AnimalsCells
    269. Effing TW, Kerstjens HAM, Monninkhof EM, van der Valk PDLPM, Wouters EFM, Postma DS, Zielhuis GA, van der Palen J. Definitions of exacerbations: does it really matter in clinical trials on COPD? Chest. 2009 Sep; 136(3):918-923. PMID: 19736196.
      Citations: 21   Fields:    Translation:Humans
    270. Bracke KR, Dentener MA, Papakonstantinou E, Vernooy JH, Demoor T, Pauwels NS, Cleutjens J, van Suylen RJ, Joos GF, Brusselle GG, Wouters EF. Enhanced deposition of low-molecular-weight hyaluronan in lungs of cigarette smoke-exposed mice. Am J Respir Cell Mol Biol. 2010 Jun; 42(6):753-61. PMID: 19675307.
      Citations: 30   Article has an altmetric score of 6    Fields:    Translation:AnimalsCells
    271. Yanbaeva DG, Wouters EF, Dentener MA, Spruit MA, Reynaert NL. Association of glutathione-S-transferase omega haplotypes with susceptibility to chronic obstructive pulmonary disease. Free Radic Res. 2009 Aug; 43(8):738-43. PMID: 19513904.
      Citations: 9   Fields:    Translation:Humans
    272. Graat-Verboom L, Spruit MA, van den Borne BE, Smeenk FW, Martens EJ, Lunde R, Wouters EF. Correlates of osteoporosis in chronic obstructive pulmonary disease: An underestimated systemic component. Respir Med. 2009 Aug; 103(8):1143-51. PMID: 19304474.
      Citations: 33   Article has an altmetric score of 3    Fields:    Translation:Humans
    273. Spruit MA, Janssen DJ, Franssen FM, Wouters EF. Rehabilitation and palliative care in lung fibrosis. Respirology. 2009 Aug; 14(6):781-7. PMID: 19703060.
      Citations: 5   Article has an altmetric score of 5    Fields:    Translation:Humans
    274. Rutten EP, Spruit MA, Wouters EF. Critical view on diagnosing muscle wasting by single-frequency bio-electrical impedance in COPD. Respir Med. 2010 Jan; 104(1):91-8. PMID: 19646856.
      Citations: 16   Fields:    Translation:Humans
    275. Willems DC, Joore MA, Nieman FH, Severens JL, Wouters EF, Hendriks JJ. Using EQ-5D in children with asthma, rheumatic disorders, diabetes, and speech/language and/or hearing disorders. Int J Technol Assess Health Care. 2009 Jul; 25(3):391-9. PMID: 19619359.
      Citations: 13   Article has an altmetric score of 3    Fields:    Translation:Humans
    276. Breyer MK, Spruit MA, Celis AP, Rutten EP, Janssen PP, Wouters EF. Highly elevated C-reactive protein levels in obese patients with COPD: a fat chance? Clin Nutr. 2009 Dec; 28(6):642-7. PMID: 19540024.
      Citations: 10   Fields:    Translation:Humans
    277. Haegens A, Heeringa P, van Suylen RJ, Steele C, Aratani Y, O'Donoghue RJ, Mutsaers SE, Mossman BT, Wouters EF, Vernooy JH. Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production. J Immunol. 2009 Jun 15; 182(12):7990-6. PMID: 19494324.
      Citations: 38   Article has an altmetric score of 3    Fields:    Translation:AnimalsCells
    278. Sillen MJH, Speksnijder CM, Eterman RA, Janssen PP, Wagers SS, Wouters EFM, Uszko-Lencer NHMK, Spruit MA. Effects of neuromuscular electrical stimulation of muscles of ambulation in patients with chronic heart failure or COPD: a systematic review of the English-language literature. Chest. 2009 Jul; 136(1):44-61. PMID: 19363213.
      Citations: 37   Article has an altmetric score of 19    Fields:    Translation:Humans
    279. Weseler AR, Geraets L, Moonen HJ, Manders RJ, van Loon LJ, Pennings HJ, Wouters EF, Bast A, Hageman GJ. Poly (ADP-ribose) polymerase-1-inhibiting flavonoids attenuate cytokine release in blood from male patients with chronic obstructive pulmonary disease or type 2 diabetes. J Nutr. 2009 May; 139(5):952-7. PMID: 19321592.
      Citations: 15   Fields:    Translation:Humans
    280. Geraets L, Haegens A, Brauers K, Haydock JA, Vernooy JH, Wouters EF, Bast A, Hageman GJ. Inhibition of LPS-induced pulmonary inflammation by specific flavonoids. Biochem Biophys Res Commun. 2009 May 08; 382(3):598-603. PMID: 19292976.
      Citations: 26   Article has an altmetric score of 6    Fields:    Translation:Animals
    281. Yanbaeva DG, Dentener MA, Spruit MA, Houwing-Duistermaat JJ, Kotz D, Passos VL, Wouters EF. IL6 and CRP haplotypes are associated with COPD risk and systemic inflammation: a case-control study. BMC Med Genet. 2009 Mar 09; 10:23. PMID: 19272152.
      Citations: 32   Fields:    Translation:Humans
    282. Janssen DJ, Alsemgeest TP, Widdershoven GA, Wouters EF, Schols JM, Spruit MA. The last wish of a patient with end stage chronic obstructive pulmonary disease. BMJ. 2008 Dec 08; 337:a2701. PMID: 19064602.
      Citations: 1   Fields:    Translation:Humans
    283. Janssen DJ, Spruit MA, Schols JM, Wouters EF. A dosage of opioids should never exceed what is necessary to relieve symptoms. Am J Respir Crit Care Med. 2008 Dec 01; 178(11):1186; author reply 1186. PMID: 19023037.
      Fields:    Translation:Humans
    284. Pitta F, Breyer MK, Hernandes NA, Teixeira D, Sant'Anna TJ, Fontana AD, Probst VS, Brunetto AF, Spruit MA, Wouters EF, Burghuber OC, Hartl S. Comparison of daily physical activity between COPD patients from Central Europe and South America. Respir Med. 2009 Mar; 103(3):421-6. PMID: 19006659.
      Citations: 21   Article has an altmetric score of 3    Fields:    Translation:Humans
    285. Gosker HR, Langen RC, Bracke KR, Joos GF, Brusselle GG, Steele C, Ward KA, Wouters EF, Schols AM. Extrapulmonary manifestations of chronic obstructive pulmonary disease in a mouse model of chronic cigarette smoke exposure. Am J Respir Cell Mol Biol. 2009 Jun; 40(6):710-6. PMID: 18988919.
      Citations: 28   Article has an altmetric score of 1    Fields:    Translation:Animals
    286. Willems DC, Joore MA, Hendriks JJ, Nieman FH, Severens JL, Wouters EF. The effectiveness of nurse-led telemonitoring of asthma: results of a randomized controlled trial. J Eval Clin Pract. 2008 Aug; 14(4):600-9. PMID: 19126178.
      Citations: 12   Article has an altmetric score of 3    Fields:    Translation:Humans
    287. Patel BD, Coxson HO, Pillai SG, Agustí AG, Calverley PM, Donner CF, Make BJ, Müller NL, Rennard SI, Vestbo J, Wouters EF, Hiorns MP, Nakano Y, Camp PG, Nasute Fauerbach PV, Screaton NJ, Campbell EJ, Anderson WH, Paré PD, Levy RD, Lake SL, Silverman EK, Lomas DA. Airway wall thickening and emphysema show independent familial aggregation in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2008 Sep 01; 178(5):500-5. PMID: 18565956.
      Citations: 119   Fields:    Translation:Humans
    288. Janssen DJ, Wouters EF, Schols JM, Spruit MA. Self-perceived symptoms and care needs of patients with severe to very severe chronic obstructive pulmonary disease, congestive heart failure or chronic renal failure and its consequences for their closest relatives: the research protocol. BMC Palliat Care. 2008 May 06; 7:5. PMID: 18460203.
      Citations: 6   Fields:    
    289. Rutten EP, Engelen MP, Gosker H, Bast A, Cosemans K, Vissers YL, Wouters EF, Deutz NE, Schols AM. Metabolic and functional effects of glutamate intake in patients with chronic obstructive pulmonary disease (COPD). Clin Nutr. 2008 Jun; 27(3):408-15. PMID: 18433945.
      Citations: 3   Fields:    Translation:Humans
    290. Sillen MJ, Janssen PP, Akkermans MA, Wouters EF, Spruit MA. The metabolic response during resistance training and neuromuscular electrical stimulation (NMES) in patients with COPD, a pilot study. Respir Med. 2008 May; 102(5):786-9. PMID: 18294832.
      Citations: 16   Article has an altmetric score of 3    Fields:    Translation:Humans
    291. Dentener MA, Creutzberg EC, Pennings HJ, Rijkers GT, Mercken E, Wouters EF. Effect of infliximab on local and systemic inflammation in chronic obstructive pulmonary disease: a pilot study. Respiration. 2008; 76(3):275-82. PMID: 18277064.
      Citations: 27   Fields:    Translation:Humans
    292. Groenewegen KH, Postma DS, Hop WC, Wielders PL, Schlösser NJ, Wouters EF. Increased systemic inflammation is a risk factor for COPD exacerbations. Chest. 2008 Feb; 133(2):350-7. PMID: 18198263.
      Citations: 37   Article has an altmetric score of 3    Fields:    Translation:Humans
    293. Spruit MA, Vanderhoven-Augustin I, Janssen PP, Wouters EF. Integration of pulmonary rehabilitation in COPD. Lancet. 2008 Jan 05; 371(9606):12-3. PMID: 18177760.
      Citations: 25   Article has an altmetric score of 3    Fields:    Translation:Humans
    294. Wouters EF, Groenewegen KH, Dentener MA, Vernooy JH. Systemic inflammation in chronic obstructive pulmonary disease: the role of exacerbations. Proc Am Thorac Soc. 2007 Dec; 4(8):626-34. PMID: 18073394.
      Citations: 31   Article has an altmetric score of 3    Fields:    Translation:Humans
    295. Pauwels R, Joos GF, Fogarty C, Faiferman I, Hirschberg S, Vessey R, Wouters EF. Bronchodilating effect of combined therapy with ipratropium bromide and ondansetron in patients with COPD. Pulm Pharmacol Ther. 2008; 21(2):385-92. PMID: 18023600.
      Fields:    Translation:HumansCTClinical Trials
    296. Geraets L, Moonen HJ, Brauers K, Wouters EF, Bast A, Hageman GJ. Dietary flavones and flavonoles are inhibitors of poly(ADP-ribose)polymerase-1 in pulmonary epithelial cells. J Nutr. 2007 Oct; 137(10):2190-5. PMID: 17884996.
      Citations: 43   Fields:    Translation:HumansCells
    297. Scharloo M, Kaptein AA, Schlösser M, Pouwels H, Bel EH, Rabe KF, Wouters EF. Illness perceptions and quality of life in patients with chronic obstructive pulmonary disease. J Asthma. 2007 Sep; 44(7):575-81. PMID: 17885862.
      Citations: 13   Fields:    Translation:Humans
    298. Spruit MA, Pennings HJ, Janssen PP, Does JD, Scroyen S, Akkermans MA, Mostert R, Wouters EF. Extra-pulmonary features in COPD patients entering rehabilitation after stratification for MRC dyspnea grade. Respir Med. 2007 Dec; 101(12):2454-63. PMID: 17765532.
      Citations: 21   Article has an altmetric score of 3    Fields:    Translation:Humans
    299. Willems DC, Joore MA, Hendriks JJ, Wouters EF, Severens JL. Cost-effectiveness of a nurse-led telemonitoring intervention based on peak expiratory flow measurements in asthmatics: results of a randomised controlled trial. Cost Eff Resour Alloc. 2007 Jul 27; 5:10. PMID: 17662113.
      Citations: 14   Article has an altmetric score of 3    
    300. Groenewegen KH, Dentener MA, Wouters EF. Longitudinal follow-up of systemic inflammation after acute exacerbations of COPD. Respir Med. 2007 Nov; 101(11):2409-15. PMID: 17644367.
      Citations: 13   Article has an altmetric score of 3    Fields:    Translation:Humans
    301. Geraets L, Moonen HJ, Brauers K, Gottschalk RW, Wouters EF, Bast A, Hageman GJ. Flavone as PARP-1 inhibitor: its effect on lipopolysaccharide induced gene-expression. Eur J Pharmacol. 2007 Nov 14; 573(1-3):241-8. PMID: 17643414.
      Citations: 6   Fields:    Translation:HumansCells
    302. Wouters EF. Decision making in chronic hypercapnic respiratory failure: a real challenge! Chest. 2007 Jun; 131(6):1622-4. PMID: 17565012.
      Fields:    Translation:Humans
    303. Gosker HR, Zeegers MP, Wouters EF, Schols AM. Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis. Thorax. 2007 Nov; 62(11):944-9. PMID: 17526675.
      Citations: 60   Article has an altmetric score of 5    Fields:    Translation:HumansCells
    304. Yanbaeva DG, Dentener MA, Creutzberg EC, Wesseling G, Wouters EF. Systemic effects of smoking. Chest. 2007 May; 131(5):1557-66. PMID: 17494805.
      Citations: 256   Article has an altmetric score of 42    Fields:    Translation:Humans
    305. Reynaert NL, Aesif SW, McGovern T, Brown A, Wouters EF, Irvin CG, Janssen-Heininger YM. Catalase overexpression fails to attenuate allergic airways disease in the mouse. J Immunol. 2007 Mar 15; 178(6):3814-21. PMID: 17339480.
      Citations: 5   Fields:    Translation:Animals
    306. Engelen MP, Rutten EP, De Castro CL, Wouters EF, Schols AM, Deutz NE. Supplementation of soy protein with branched-chain amino acids alters protein metabolism in healthy elderly and even more in patients with chronic obstructive pulmonary disease. Am J Clin Nutr. 2007 Feb; 85(2):431-9. PMID: 17284740.
      Citations: 31   Article has an altmetric score of 20    Fields:    Translation:HumansCTClinical Trials
    307. Spruit MA, Wouters EF. New modalities of pulmonary rehabilitation in patients with chronic obstructive pulmonary disease. Sports Med. 2007; 37(6):501-18. PMID: 17503876.
      Citations: 3   Article has an altmetric score of 3    Fields:    Translation:Humans
    308. Willems DC, Joore MA, Hendriks JJ, van Duurling RA, Wouters EF, Severens JL. Process evaluation of a nurse-led telemonitoring programme for patients with asthma. J Telemed Telecare. 2007; 13(6):310-7. PMID: 17785028.
      Citations: 6   Article has an altmetric score of 9    Fields:    Translation:Humans
    309. van der Velden JL, Langen RC, Kelders MC, Willems J, Wouters EF, Janssen-Heininger YM, Schols AM. Myogenic differentiation during regrowth of atrophied skeletal muscle is associated with inactivation of GSK-3beta. Am J Physiol Cell Physiol. 2007 May; 292(5):C1636-44. PMID: 17166938.
      Citations: 19   Translation:AnimalsCells
    310. Vernooy JH, Möller GM, van Suylen RJ, van Spijk MP, Cloots RH, Hoet PH, Pennings HJ, Wouters EF. Increased granzyme A expression in type II pneumocytes of patients with severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2007 Mar 01; 175(5):464-72. PMID: 17138956.
      Citations: 23   Article has an altmetric score of 6    Fields:    Translation:Humans
    311. Dentener MA, Wouters EF. Tumor necrosis factor inhibitors for rheumatoid arthritis. N Engl J Med. 2006 Nov 09; 355(19):2047-8; author reply 2048. PMID: 17099951.
      Citations: 1   Fields:    Translation:Humans
    312. Reynaert NL, Wouters EF, Janssen-Heininger YM. Modulation of glutaredoxin-1 expression in a mouse model of allergic airway disease. Am J Respir Cell Mol Biol. 2007 Feb; 36(2):147-51. PMID: 16980552.
      Citations: 39   Fields:    Translation:AnimalsCells
    313. Bolton CE, Broekhuizen R, Ionescu AA, Nixon LS, Wouters EF, Shale DJ, Schols AM. Cellular protein breakdown and systemic inflammation are unaffected by pulmonary rehabilitation in COPD. Thorax. 2007 Feb; 62(2):109-14. PMID: 16928709.
      Citations: 11   Fields:    Translation:Humans
    314. Reynaert NL, van der Vliet A, Guala AS, McGovern T, Hristova M, Pantano C, Heintz NH, Heim J, Ho YS, Matthews DE, Wouters EF, Janssen-Heininger YM. Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta. Proc Natl Acad Sci U S A. 2006 Aug 29; 103(35):13086-91. PMID: 16916935.
      Citations: 164   Article has an altmetric score of 3    Fields:    Translation:AnimalsCells
    315. Geraets L, Moonen HJ, Wouters EF, Bast A, Hageman GJ. Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations. Biochem Pharmacol. 2006 Sep 28; 72(7):902-10. PMID: 16870158.
      Citations: 30   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    316. Langen RC, Schols AM, Kelders MC, van der Velden JL, Wouters EF, Janssen-Heininger YM. Muscle wasting and impaired muscle regeneration in a murine model of chronic pulmonary inflammation. Am J Respir Cell Mol Biol. 2006 Dec; 35(6):689-96. PMID: 16794259.
      Citations: 39   Fields:    Translation:AnimalsCells
    317. Chavannes NH, Vernooy JH, Schermer TR, Jacobs JA, Dentener MA, van Weel C, van Schayck OC, Wouters EF. Patterns of inflammation and the use of reversibility testing in smokers with airway complaints. BMC Pulm Med. 2006 Jun 01; 6:11. PMID: 16740168.
      Citations: 2   Fields:    Translation:HumansCTClinical Trials
    318. Wouters EF. Approaches to improving health status in chronic obstructive pulmonary disease: one or several? Proc Am Thorac Soc. 2006 May; 3(3):262-9. PMID: 16636096.
      Fields:    Translation:Humans
    319. Rutten EP, Franssen FM, Engelen MP, Wouters EF, Deutz NE, Schols AM. Greater whole-body myofibrillar protein breakdown in cachectic patients with chronic obstructive pulmonary disease. Am J Clin Nutr. 2006 Apr; 83(4):829-34. PMID: 16600935.
      Citations: 13   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    320. Rutten EP, Engelen MP, Wouters EF, Deutz NE, Schols AM. Effect of glutamate ingestion on whole-body glutamate turnover in healthy elderly and patients with chronic obstructive pulmonary disease. Nutrition. 2006 May; 22(5):496-503. PMID: 16531008.
      Citations: 2   Fields:    Translation:Humans
    321. Spruit MA, Janssen PP, Willemsen SC, Hochstenbag MM, Wouters EF. Exercise capacity before and after an 8-week multidisciplinary inpatient rehabilitation program in lung cancer patients: a pilot study. Lung Cancer. 2006 May; 52(2):257-60. PMID: 16529844.
      Citations: 37   Article has an altmetric score of 10    Fields:    Translation:HumansCTClinical Trials
    322. Yanbaeva DG, Dentener MA, Creutzberg EC, Wouters EF. Systemic inflammation in COPD: is genetic susceptibility a key factor? COPD. 2006 Mar; 3(1):51-61. PMID: 17175665.
      Citations: 11   Article has an altmetric score of 1    Fields:    Translation:Humans
    323. Reynaert NL, Ckless K, Guala AS, Wouters EF, van der Vliet A, Janssen-Heininger YM. In situ detection of S-glutathionylated proteins following glutaredoxin-1 catalyzed cysteine derivatization. Biochim Biophys Acta. 2006 Mar; 1760(3):380-7. PMID: 16515838.
      Citations: 38   Article has an altmetric score of 3    Fields:    Translation:AnimalsCells
    324. Wouters EF. Cachexia and chronic respiratory failure: lessons from ventilatory support. Respir Care. 2006 Feb; 51(2):121-2. PMID: 16441954.
      Fields:    Translation:Humans
    325. Willems DC, Joore MA, Hendriks JJ, Wouters EF, Severens JL. Cost-effectiveness of self-management in asthma: a systematic review of peak flow monitoring interventions. Int J Technol Assess Health Care. 2006; 22(4):436-42. PMID: 16984676.
      Citations: 6   Article has an altmetric score of 3    Fields:    Translation:Humans
    326. Rutten EP, Engelen MP, Wouters EF, Schols AM, Deutz NE. Metabolic effects of glutamine and glutamate ingestion in healthy subjects and in persons with chronic obstructive pulmonary disease. Am J Clin Nutr. 2006 Jan; 83(1):115-23. PMID: 16400059.
      Citations: 8   Fields:    Translation:Humans
    327. Wouters EF. Muscle wasting in chronic obstructive pulmonary disease: to bother and to measure! Am J Respir Crit Care Med. 2006 Jan 01; 173(1):4-5. PMID: 16368791.
      Citations: 6   Article has an altmetric score of 3    Fields:    Translation:Humans
    328. Gosker HR, Schrauwen P, Broekhuizen R, Hesselink MK, Moonen-Kornips E, Ward KA, Franssen FM, Wouters EF, Schols AM. Exercise training restores uncoupling protein-3 content in limb muscles of patients with chronic obstructive pulmonary disease. Am J Physiol Endocrinol Metab. 2006 May; 290(5):E976-81. PMID: 16352674.
      Citations: 11   Fields:    Translation:HumansCellsCTClinical Trials
    329. Celli BR, Calverley PM, Rennard SI, Wouters EF, Agusti A, Anthonisen N, Macnee W, Jones P, Pride N, Rodriguez-Roisin R, Rossi A, Wanner A. Proposal for a multidimensional staging system for chronic obstructive pulmonary disease. Respir Med. 2005 Dec; 99(12):1546-54. PMID: 16291077.
      Citations: 7   Fields:    Translation:Humans
    330. Moonen HJ, Geraets L, Vaarhorst A, Bast A, Wouters EF, Hageman GJ. Theophylline prevents NAD+ depletion via PARP-1 inhibition in human pulmonary epithelial cells. Biochem Biophys Res Commun. 2005 Dec 30; 338(4):1805-10. PMID: 16289039.
      Citations: 15   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    331. van der Velden JL, Langen RC, Kelders MC, Wouters EF, Janssen-Heininger YM, Schols AM. Inhibition of glycogen synthase kinase-3beta activity is sufficient to stimulate myogenic differentiation. Am J Physiol Cell Physiol. 2006 Feb; 290(2):C453-62. PMID: 16162663.
      Citations: 37   Translation:AnimalsCells
    332. Rutten EP, Engelen MP, Castro CL, Wouters EF, Schols AM, Deutz NE. Decreased whole-body and splanchnic glutamate metabolism in healthy elderly men and patients with chronic obstructive pulmonary disease in the postabsorptive state and in response to feeding. J Nutr. 2005 Sep; 135(9):2166-70. PMID: 16140893.
      Citations: 3   Fields:    Translation:Humans
    333. Engelen MP, Rutten EP, De Castro CL, Wouters EF, Schols AM, Deutz NE. Altered interorgan response to feeding in patients with chronic obstructive pulmonary disease. Am J Clin Nutr. 2005 Aug; 82(2):366-72. PMID: 16087980.
      Citations: 11   Fields:    Translation:Humans
    334. Mercken EM, Hageman GJ, Schols AM, Akkermans MA, Bast A, Wouters EF. Rehabilitation decreases exercise-induced oxidative stress in chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2005 Oct 15; 172(8):994-1001. PMID: 16040783.
      Citations: 39   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    335. Wagena EJ, van Amelsvoort LG, Kant I, Wouters EF. Chronic bronchitis, cigarette smoking, and the subsequent onset of depression and anxiety: results from a prospective population-based cohort study. Psychosom Med. 2005 Jul-Aug; 67(4):656-60. PMID: 16046384.
      Citations: 13   Fields:    Translation:Humans
    336. Broekhuizen R, Creutzberg EC, Weling-Scheepers CA, Wouters EF, Schols AM. Optimizing oral nutritional drink supplementation in patients with chronic obstructive pulmonary disease. Br J Nutr. 2005 Jun; 93(6):965-71. PMID: 16022768.
      Citations: 5   Article has an altmetric score of 9    Fields:    Translation:Humans
    337. Reynaert NL, Ckless K, Wouters EF, van der Vliet A, Janssen-Heininger YM. Nitric oxide and redox signaling in allergic airway inflammation. Antioxid Redox Signal. 2005 Jan-Feb; 7(1-2):129-43. PMID: 15650402.
      Citations: 13   Article has an altmetric score of 6    Fields:    Translation:HumansCells
    338. Franssen FM, Broekhuizen R, Janssen PP, Wouters EF, Schols AM. Limb muscle dysfunction in COPD: effects of muscle wasting and exercise training. Med Sci Sports Exerc. 2005 Jan; 37(1):2-9. PMID: 15632660.
      Citations: 31   Fields:    Translation:HumansCTClinical Trials
    339. Gosker HR, Bast A, Haenen GR, Fischer MA, van der Vusse GJ, Wouters EF, Schols AM. Altered antioxidant status in peripheral skeletal muscle of patients with COPD. Respir Med. 2005 Jan; 99(1):118-25. PMID: 15672860.
      Citations: 16   Fields:    Translation:HumansCells
    340. Wouters EF. Local and systemic inflammation in chronic obstructive pulmonary disease. Proc Am Thorac Soc. 2005; 2(1):26-33. PMID: 16113466.
      Citations: 67   Fields:    Translation:Humans
    341. Vernooy JH, Lindeman JH, Jacobs JA, Hanemaaijer R, Wouters EF. Increased activity of matrix metalloproteinase-8 and matrix metalloproteinase-9 in induced sputum from patients with COPD. Chest. 2004 Dec; 126(6):1802-10. PMID: 15596677.
      Citations: 58   Fields:    Translation:HumansCells
    342. de Blaauw I, Schols AM, Koerts-deLang E, Wouters EF, Deutz NE. De novo glutamine synthesis induced by corticosteroids in vivo in rats is secondary to weight loss. Clin Nutr. 2004 Oct; 23(5):1035-42. PMID: 15380893.
      Citations: 1   Fields:    Translation:Animals
    343. Wagena EJ, Kant I, van Amelsvoort LG, Wouters EF, van Schayck CP, Swaen GM. Risk of depression and anxiety in employees with chronic bronchitis: the modifying effect of cigarette smoking. Psychosom Med. 2004 Sep-Oct; 66(5):729-34. PMID: 15385698.
      Citations: 10   Fields:    Translation:Humans
    344. Reynaert NL, Ckless K, Korn SH, Vos N, Guala AS, Wouters EF, van der Vliet A, Janssen-Heininger YM. Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation. Proc Natl Acad Sci U S A. 2004 Jun 15; 101(24):8945-50. PMID: 15184672.
      Citations: 122   Article has an altmetric score of 3    Fields:    Translation:HumansAnimalsCells
    345. Franssen FM, Broekhuizen R, Janssen PP, Wouters EF, Schols AM. Effects of whole-body exercise training on body composition and functional capacity in normal-weight patients with COPD. Chest. 2004 Jun; 125(6):2021-8. PMID: 15189917.
      Citations: 23   Article has an altmetric score of 10    Fields:    Translation:Humans
    346. Verbraecken J, Hoitsma E, van der Grinten CP, Cobben NA, Wouters EF, Drent M. Sleep disturbances associated with periodic leg movements in chronic sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2004 Jun; 21(2):137-46. PMID: 15281435.
      Citations: 6   Fields:    Translation:Humans
    347. Langen RC, Van Der Velden JL, Schols AM, Kelders MC, Wouters EF, Janssen-Heininger YM. Tumor necrosis factor-alpha inhibits myogenic differentiation through MyoD protein destabilization. FASEB J. 2004 Feb; 18(2):227-37. PMID: 14769817.
      Citations: 99   Fields:    Translation:AnimalsCells
    348. Wagena EJ, Kant I, Huibers MJ, van Amelsvoort LG, Swaen GM, Wouters EF, van Schayck CP. Psychological distress and depressed mood in employees with asthma, chronic bronchitis or emphysema: a population-based observational study on prevalence and the relationship with smoking cigarettes. Eur J Epidemiol. 2004; 19(2):147-53. PMID: 15080082.
      Citations: 8   Article has an altmetric score of 3    Fields:    Translation:Humans
    349. Creutzberg EC, Wouters EF, Mostert R, Pluymers RJ, Schols AM. A role for anabolic steroids in the rehabilitation of patients with COPD? A double-blind, placebo-controlled, randomized trial. Chest. 2003 Nov; 124(5):1733-42. PMID: 14605042.
      Citations: 36   Article has an altmetric score of 12    Fields:    Translation:HumansCTClinical Trials
    350. Groenewegen KH, Schols AM, Wouters EF. Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD. Chest. 2003 Aug; 124(2):459-67. PMID: 12907529.
      Citations: 178   Article has an altmetric score of 23    Fields:    Translation:Humans
    351. Hageman GJ, Larik I, Pennings HJ, Haenen GR, Wouters EF, Bast A. Systemic poly(ADP-ribose) polymerase-1 activation, chronic inflammation, and oxidative stress in COPD patients. Free Radic Biol Med. 2003 Jul 15; 35(2):140-8. PMID: 12853070.
      Citations: 23   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    352. Groenewegen KH, Wouters EF. Bacterial infections in patients requiring admission for an acute exacerbation of COPD; a 1-year prospective study. Respir Med. 2003 Jul; 97(7):770-7. PMID: 12854626.
      Citations: 25   Article has an altmetric score of 3    Fields:    Translation:Humans
    353. Goris AH, Vermeeren MA, Wouters EF, Schols AM, Westerterp KR. Energy balance in depleted ambulatory patients with chronic obstructive pulmonary disease: the effect of physical activity and oral nutritional supplementation. Br J Nutr. 2003 May; 89(5):725-31. PMID: 12720592.
      Citations: 14   Article has an altmetric score of 12    Fields:    Translation:Humans
    354. Gosker HR, Lencer NH, Franssen FM, van der Vusse GJ, Wouters EF, Schols AM. Striking similarities in systemic factors contributing to decreased exercise capacity in patients with severe chronic heart failure or COPD. Chest. 2003 May; 123(5):1416-24. PMID: 12740256.
      Citations: 39   Article has an altmetric score of 11    Fields:    Translation:Humans
    355. Engelen MP, Deutz NE, Mostert R, Wouters EF, Schols AM. Response of whole-body protein and urea turnover to exercise differs between patients with chronic obstructive pulmonary disease with and without emphysema. Am J Clin Nutr. 2003 Apr; 77(4):868-74. PMID: 12663285.
      Citations: 6   Fields:    Translation:Humans
    356. Langen RC, Schols AM, Kelders MC, Wouters EF, Janssen-Heininger YM. Enhanced myogenic differentiation by extracellular matrix is regulated at the early stages of myogenesis. In Vitro Cell Dev Biol Anim. 2003 Mar-Apr; 39(3-4):163-9. PMID: 14505430.
      Citations: 19   Article has an altmetric score of 6    Fields:    Translation:AnimalsCells
    357. Creutzberg EC, Wouters EF, Mostert R, Weling-Scheepers CA, Schols AM. Efficacy of nutritional supplementation therapy in depleted patients with chronic obstructive pulmonary disease. Nutrition. 2003 Feb; 19(2):120-7. PMID: 12591542.
      Citations: 24   Article has an altmetric score of 9    Fields:    Translation:Humans
    358. Wagena EJ, Zeegers MP, van Schayck CP, Wouters EF. Benefits and risks of pharmacological smoking cessation therapies in chronic obstructive pulmonary disease. Drug Saf. 2003; 26(6):381-403. PMID: 12688831.
      Citations: 10   Article has an altmetric score of 3    Fields:    Translation:Humans
    359. Küçükaycan M, Van Krugten M, Pennings HJ, Huizinga TW, Buurman WA, Dentener MA, Wouters EF. Tumor necrosis factor-alpha +489G/A gene polymorphism is associated with chronic obstructive pulmonary disease. Respir Res. 2002; 3:29. PMID: 12537602.
      Citations: 11   Article has an altmetric score of 3    Fields:    Translation:Humans
    360. Franssen FM, Wouters EF, Baarends EM, Akkermans MA, Schols AM. Arm mechanical efficiency and arm exercise capacity are relatively preserved in chronic obstructive pulmonary disease. Med Sci Sports Exerc. 2002 Oct; 34(10):1570-6. PMID: 12370557.
      Citations: 11   Article has an altmetric score of 3    Fields:    Translation:Humans
    361. Langen RC, Schols AM, Kelders MC, Van Der Velden JL, Wouters EF, Janssen-Heininger YM. Tumor necrosis factor-alpha inhibits myogenesis through redox-dependent and -independent pathways. Am J Physiol Cell Physiol. 2002 Sep; 283(3):C714-21. PMID: 12176728.
      Citations: 34   Translation:AnimalsCells
    362. Godschalk RW, Feldker DE, Borm PJ, Wouters EF, van Schooten FJ. Body mass index modulates aromatic DNA adduct levels and their persistence in smokers. Cancer Epidemiol Biomarkers Prev. 2002 Aug; 11(8):790-3. PMID: 12163336.
      Citations: 26   Fields:    Translation:HumansCells
    363. Langendijk JA, Aaronson NK, de Jong JM, ten Velde GP, Muller MJ, Slotman BJ, Wouters EF. Quality of life after curative radiotherapy in Stage I non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2002 Jul 15; 53(4):847-53. PMID: 12095549.
      Citations: 9   Article has an altmetric score of 3    Fields:    Translation:Humans
    364. Gosker HR, Engelen MP, van Mameren H, van Dijk PJ, van der Vusse GJ, Wouters EF, Schols AM. Muscle fiber type IIX atrophy is involved in the loss of fat-free mass in chronic obstructive pulmonary disease. Am J Clin Nutr. 2002 Jul; 76(1):113-9. PMID: 12081824.
      Citations: 35   Article has an altmetric score of 4    Fields:    Translation:HumansCells
    365. Rothkrantz-Kos S, Drent M, Vuil H, De Boer M, Bast A, Wouters EF, Roos D, van Dieijen-Visser MP. Decreased redox state in red blood cells from patients with sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2002 Jun; 19(2):114-20. PMID: 12102606.
      Citations: 1   Fields:    Translation:HumansCells
    366. Vernooy JH, Dentener MA, van Suylen RJ, Buurman WA, Wouters EF. Long-term intratracheal lipopolysaccharide exposure in mice results in chronic lung inflammation and persistent pathology. Am J Respir Cell Mol Biol. 2002 Jan; 26(1):152-9. PMID: 11751215.
      Citations: 75   Article has an altmetric score of 3    Fields:    Translation:AnimalsCells