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Donald L Durden
Institution
Levine Cancer Institute
Address
Charlotte
North Carolina
United States
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Publication Timeline
COVID-19 publications
All Publications
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To see the data from both graphs as text,
click here
.
Year
Publications
2001
1
2002
3
2003
2
2004
1
2005
2
2006
3
2007
3
2008
2
2009
4
2010
2
2013
3
2014
7
2015
2
2016
3
2017
3
2018
1
2019
2
2021
1
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To return to the graphs,
click here
.
Publication Field Summary
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
Publication List
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
Show:
All coronarirus related publications
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Covid-19 specific publications
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All publications
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Oldest
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Most Cited
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Most Discussed
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Pathania AS
,
Prathipati P
,
Abdul BA
,
Chava S
,
Katta SS
,
Gupta SC
,
Gangula PR
,
Pandey MK
,
Durden DL
,
Byrareddy SN
,
Challagundla KB
. COVID-19 and Cancer Comorbidity: Therapeutic Opportunities and Challenges. Theranostics. 2021; 11(2):731-753.
PMID:
33391502
.
Citations:
8
Fields:
Dia
Diagnostic Imaging
Mol
Molecular Biology
Nan
Nanotechnology
The
Therapeutics
Translation:
Humans
Cells
PH
Public Health
Joshi S, Singh AR,
Liu KX
, Pham TV, Zulcic M, Skola D, Chun HB, Glass CK, Morales GA, Garlich JR,
Durden DL
. SF2523: Dual PI3K/BRD4 Inhibitor Blocks Tumor Immunosuppression and Promotes Adaptive Immune Responses in Cancer. Mol Cancer Ther. 2019 06; 18(6):1036-1044.
PMID:
31018997
.
Citations:
15
Translation:
Animals
Cells
Joshi S,
Durden DL
. Combinatorial Approach to Improve Cancer Immunotherapy: Rational Drug Design Strategy to Simultaneously Hit Multiple Targets to Kill Tumor Cells and to Activate the Immune System. J Oncol. 2019; 2019:5245034.
PMID:
30853982
.
Citations:
32
Campbell GR
, Bruckman RS, Herns SD, Joshi S,
Durden DL
,
Spector SA
. Induction of autophagy by PI3K/MTOR and PI3K/MTOR/BRD4 inhibitors suppresses HIV-1 replication. J Biol Chem. 2018 04 20; 293(16):5808-5820.
PMID:
29475942
.
Citations:
19
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Joshi S, Singh AR, Wong SS, Zulcic M, Jiang M, Pardo A, Selman M, Hagood JS,
Durden DL
. Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype. PLoS One. 2017; 12(8):e0182851.
PMID:
28817691
.
Citations:
10
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Nguyen HA,
Durden DL
, Lavie A. The differential ability of asparagine and glutamine in promoting the closed/active enzyme conformation rationalizes the Wolinella succinogenes L-asparaginase substrate specificity. Sci Rep. 2017 01 31; 7:41643.
PMID:
28139703
.
Citations:
3
Fields:
Sci
Science
Translation:
Cells
Andrews FH, Singh AR, Joshi S, Smith CA, Morales GA, Garlich JR,
Durden DL
,
Kutateladze TG
. Dual-activity PI3K-BRD4 inhibitor for the orthogonal inhibition of MYC to block tumor growth and metastasis. Proc Natl Acad Sci U S A. 2017 02 14; 114(7):E1072-E1080.
PMID:
28137841
.
Citations:
32
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Erdreich-Epstein A, Singh AR, Joshi S, Vega FM, Guo P, Xu J, Groshen S, Ye W, Millard M, Campan M,
Morales G
, Garlich JR, Laird PW, Seeger RC, Shimada H,
Durden DL
. Association of high microvessel avß3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126. Oncotarget. 2017 Aug 08; 8(32):52193-52210.
PMID:
28881723
.
Citations:
13
Fields:
Neo
Neoplasms
Singh AR, Joshi S, Burgoyne AM, Sicklick JK, Ikeda S,
Kono Y
, Garlich JR, Morales GA,
Durden DL
. Single Agent and Synergistic Activity of the "First-in-Class" Dual PI3K/BRD4 Inhibitor SF1126 with Sorafenib in Hepatocellular Carcinoma. Mol Cancer Ther. 2016 11; 15(11):2553-2562.
PMID:
27496136
.
Citations:
20
Translation:
Humans
Animals
Cells
Singh AR, Joshi S, Zulcic M, Alcaraz M, Garlich JR, Morales GA, Cho YJ, Bao L, Levy ML, Newbury R,
Malicki D
,
Messer K
, Crawford J,
Durden DL
. PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma. PLoS One. 2016; 11(3):e0150836.
PMID:
26938241
.
Citations:
13
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Bhat V, Olmer M, Joshi S,
Durden DL
, Cramer TJ, Barnes RF, Ball ST, Hughes TH, Silva M, Luck JV, Moore RE, Mosnier LO, von Drygalski A. Vascular remodeling underlies rebleeding in hemophilic arthropathy. Am J Hematol. 2015 Nov; 90(11):1027-35.
PMID:
26257191
.
Citations:
24
Fields:
Hem
Hematology
Translation:
Humans
Animals
Joshi S, Singh AR,
Durden DL
. Pan-PI-3 kinase inhibitor SF1126 shows antitumor and antiangiogenic activity in renal cell carcinoma. Cancer Chemother Pharmacol. 2015 Mar; 75(3):595-608.
PMID:
25578041
.
Citations:
12
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Singh AR, Joshi S, George E,
Durden DL
. Anti-tumor effect of a novel PI3-kinase inhibitor, SF1126, in (12)?V-Ha-Ras transgenic mouse glioma model. Cancer Cell Int. 2014; 14(1):105.
PMID:
25425962
.
Citations:
9
Joshi S, Singh AR, Zulcic M,
Durden DL
. A macrophage-dominant PI3K isoform controls hypoxia-induced HIF1a and HIF2a stability and tumor growth, angiogenesis, and metastasis. Mol Cancer Res. 2014 Oct; 12(10):1520-31.
PMID:
25103499
.
Citations:
48
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Animals
Cells
Hartman LL, Crawford JR, Makale MT, Milburn M, Joshi S,
Salazar AM
, Hasenauer B, VandenBerg SR, MacDonald TJ,
Durden DL
. Pediatric phase II trials of poly-ICLC in the management of newly diagnosed and recurrent brain tumors. J Pediatr Hematol Oncol. 2014 Aug; 36(6):451-7.
PMID:
24309609
.
Citations:
17
Fields:
Hem
Hematology
Neo
Neoplasms
Ped
Pediatrics
Translation:
Humans
CT
Clinical Trials
Joshi S, Singh AR,
Durden DL
. MDM2 regulates hypoxic hypoxia-inducible factor 1a stability in an E3 ligase, proteasome, and PTEN-phosphatidylinositol 3-kinase-AKT-dependent manner. J Biol Chem. 2014 Aug 15; 289(33):22785-22797.
PMID:
24982421
.
Citations:
34
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Singh AR, Peirce SK, Joshi S,
Durden DL
. PTEN and PI-3 kinase inhibitors control LPS signaling and the lymphoproliferative response in the CD19+ B cell compartment. Exp Cell Res. 2014 Sep 10; 327(1):78-90.
PMID:
24881819
.
Citations:
9
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Joshi S, Singh AR, Zulcic M,
Durden DL
. A PKC-SHP1 signaling axis desensitizes Fc? receptor signaling by reducing the tyrosine phosphorylation of CBL and regulates Fc?R mediated phagocytosis. BMC Immunol. 2014 May 07; 15:18.
PMID:
24886428
.
Citations:
3
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Joshi S, Singh AR, Zulcic M, Bao L,
Messer K
,
Ideker T
, Dutkowski J,
Durden DL
. Rac2 controls tumor growth, metastasis and M1-M2 macrophage differentiation in vivo. PLoS One. 2014; 9(4):e95893.
PMID:
24770346
.
Citations:
44
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Animals
Cells
Muh CR
, Joshi S, Singh AR,
Kesari S
,
Durden DL
, Makale MT. PTEN status mediates 2ME2 anti-tumor efficacy in preclinical glioblastoma models: role of HIF1a suppression. J Neurooncol. 2014 Jan; 116(1):89-97.
PMID:
24162827
.
Citations:
8
Fields:
Neo
Neoplasms
Neu
Neurology
Translation:
Humans
Animals
Cells
Morales GA, Garlich JR, Su J, Peng X, Newblom J, Weber K,
Durden DL
. Synthesis and cancer stem cell-based activity of substituted 5-morpholino-7H-thieno[3,2-b]pyran-7-ones designed as next generation PI3K inhibitors. J Med Chem. 2013 Mar 14; 56(5):1922-39.
PMID:
23410005
.
Citations:
12
Fields:
Che
Chemistry
Translation:
Humans
Cells
De P
, Dey N, Terakedis B, Bergsagel PL, Li ZH, Mahadevan D, Garlich JR, Trudel S, Makale MT,
Durden DL
. An integrin-targeted, pan-isoform, phosphoinositide-3 kinase inhibitor, SF1126, has activity against multiple myeloma in vivo. Cancer Chemother Pharmacol. 2013 Apr; 71(4):867-81.
PMID:
23355037
.
Citations:
10
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Animals
Cells
CT
Clinical Trials
Peirce SK, Findley HW, Prince C, Dasgupta A, Cooper T,
Durden DL
. The PI-3 kinase-Akt-MDM2-survivin signaling axis in high-risk neuroblastoma: a target for PI-3 kinase inhibitor intervention. Cancer Chemother Pharmacol. 2011 Aug; 68(2):325-35.
PMID:
20972874
.
Citations:
12
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Castellino RC, Barwick BG, Schniederjan M, Buss MC, Becher O, Hambardzumyan D, Macdonald TJ, Brat DJ,
Durden DL
. Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma. PLoS One. 2010 May 26; 5(5):e10849.
PMID:
20520772
.
Citations:
25
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Animals
Cells
Crosswell HE, Dasgupta A, Alvarado CS, Watt T, Christensen JG,
De P
,
Durden DL
, Findley HW. PHA665752, a small-molecule inhibitor of c-Met, inhibits hepatocyte growth factor-stimulated migration and proliferation of c-Met-positive neuroblastoma cells. BMC Cancer. 2009 Nov 25; 9:411.
PMID:
19939254
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ozbay T,
Durden DL
, Liu T,
O'Regan RM
, Nahta R. In vitro evaluation of pan-PI3-kinase inhibitor SF1126 in trastuzumab-sensitive and trastuzumab-resistant HER2-over-expressing breast cancer cells. Cancer Chemother Pharmacol. 2010 Mar; 65(4):697-706.
PMID:
19636556
.
Citations:
16
Fields:
Ant
Antineoplastic Agents
Neo
Neoplasms
Translation:
Humans
Cells
Gu L, Zhu N, Zhang H,
Durden DL
, Feng Y, Zhou M. Regulation of XIAP translation and induction by MDM2 following irradiation. Cancer Cell. 2009 May 05; 15(5):363-75.
PMID:
19411066
.
Citations:
77
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Rong Y
, Belozerov VE, Tucker-Burden C,
Chen G
,
Durden DL
, Olson JJ, Van Meir EG,
Mackman N
, Brat DJ. Epidermal growth factor receptor and PTEN modulate tissue factor expression in glioblastoma through JunD/activator protein-1 transcriptional activity. Cancer Res. 2009 Mar 15; 69(6):2540-9.
PMID:
19276385
.
Citations:
54
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Dey N, Crosswell HE,
De P
, Parsons R, Peng Q, Su JD,
Durden DL
. The protein phosphatase activity of PTEN regulates SRC family kinases and controls glioma migration. Cancer Res. 2008 Mar 15; 68(6):1862-71.
PMID:
18339867
.
Citations:
83
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Garlich JR,
De P
, Dey N, Su JD, Peng X, Miller A, Murali R,
Lu Y
, Mills GB, Kundra V, Shu HK, Peng Q,
Durden DL
. A vascular targeted pan phosphoinositide 3-kinase inhibitor prodrug, SF1126, with antitumor and antiangiogenic activity. Cancer Res. 2008 Jan 01; 68(1):206-15.
PMID:
18172313
.
Citations:
102
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Li Y, Yan J,
De P
, Chang HC, Yamauchi A, Christopherson KW, Paranavitana NC, Peng X, Kim C, Munugalavadla V, Munugulavadla V,
Kapur R
, Chen H, Shou W, Stone JC,
Kaplan MH
, Dinauer MC,
Durden DL
, Quilliam LA. Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins. J Immunol. 2007 Dec 15; 179(12):8322-31.
PMID:
18056377
.
Citations:
71
Fields:
All
Allergy and Immunology
Translation:
Animals
Cells
Castellino RC,
Durden DL
. Mechanisms of disease: the PI3K-Akt-PTEN signaling node--an intercept point for the control of angiogenesis in brain tumors. Nat Clin Pract Neurol. 2007 Dec; 3(12):682-93.
PMID:
18046441
.
Citations:
47
Fields:
Neu
Neurology
Translation:
Humans
Animals
Cells
Dey N, De PK,
Wang M
, Zhang H, Dobrota EA, Robertson KA,
Durden DL
. CSK controls retinoic acid receptor (RAR) signaling: a RAR-c-SRC signaling axis is required for neuritogenic differentiation. Mol Cell Biol. 2007 Jun; 27(11):4179-97.
PMID:
17325034
.
Citations:
23
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Reinert RB, Oberle LM, Wek SA, Bunpo P, Wang XP, Mileva I, Goodwin LO, Aldrich CJ,
Durden DL
, McNurlan MA, Wek RC, Anthony TG. Role of glutamine depletion in directing tissue-specific nutrient stress responses to L-asparaginase. J Biol Chem. 2006 Oct 20; 281(42):31222-33.
PMID:
16931516
.
Citations:
41
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Rong Y
, Hu F, Huang R,
Mackman N
, Horowitz JM,
Jensen RL
,
Durden DL
, Van Meir EG, Brat DJ. Early growth response gene-1 regulates hypoxia-induced expression of tissue factor in glioblastoma multiforme through hypoxia-inducible factor-1-independent mechanisms. Cancer Res. 2006 Jul 15; 66(14):7067-74.
PMID:
16849552
.
Citations:
34
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Rong Y
,
Durden DL
, Van Meir EG, Brat DJ. 'Pseudopalisading' necrosis in glioblastoma: a familiar morphologic feature that links vascular pathology, hypoxia, and angiogenesis. J Neuropathol Exp Neurol. 2006 Jun; 65(6):529-39.
PMID:
16783163
.
Citations:
202
Fields:
Neu
Neurology
Pat
Pathology
Translation:
Humans
Animals
Dey N, Howell BW, De PK,
Durden DL
. CSK negatively regulates nerve growth factor induced neural differentiation and augments AKT kinase activity. Exp Cell Res. 2005 Jul 01; 307(1):1-14.
PMID:
15890337
.
Citations:
12
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Rong Y
, Post DE, Pieper RO,
Durden DL
, Van Meir EG, Brat DJ. PTEN and hypoxia regulate tissue factor expression and plasma coagulation by glioblastoma. Cancer Res. 2005 Feb 15; 65(4):1406-13.
PMID:
15735028
.
Citations:
64
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Moon KD, Post CB,
Durden DL
, Zhou Q,
De P
, Harrison ML, Geahlen RL. Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase. J Biol Chem. 2005 Jan 14; 280(2):1543-51.
PMID:
15536084
.
Citations:
33
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Pradip D, Peng X,
Durden DL
. Rac2 specificity in macrophage integrin signaling: potential role for Syk kinase. J Biol Chem. 2003 Oct 24; 278(43):41661-9.
PMID:
12917394
.
Citations:
20
Fields:
Bio
Biochemistry
Translation:
Animals
Cells
Su JD, Mayo LD, Donner DB,
Durden DL
. PTEN and phosphatidylinositol 3'-kinase inhibitors up-regulate p53 and block tumor-induced angiogenesis: evidence for an effect on the tumor and endothelial compartment. Cancer Res. 2003 Jul 01; 63(13):3585-92.
PMID:
12839945
.
Citations:
35
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Erdreich-Epstein A, Tran LB, Bowman NN, Wang H, Cabot MC,
Durden DL
, Vlckova J, Reynolds CP, Stins MF, Groshen S, Millard M. Ceramide signaling in fenretinide-induced endothelial cell apoptosis. J Biol Chem. 2002 Dec 20; 277(51):49531-7.
PMID:
12388538
.
Citations:
26
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
Kant AM,
De P
, Peng X, Yi T,
Rawlings DJ
, Kim JS,
Durden DL
. SHP-1 regulates Fcgamma receptor-mediated phagocytosis and the activation of RAC. Blood. 2002 Sep 01; 100(5):1852-9.
PMID:
12176909
.
Citations:
30
Fields:
Hem
Hematology
Translation:
Animals
Cells
Kim JS, Peng X, De PK, Geahlen RL,
Durden DL
. PTEN controls immunoreceptor (immunoreceptor tyrosine-based activation motif) signaling and the activation of Rac. Blood. 2002 Jan 15; 99(2):694-7.
PMID:
11781256
.
Citations:
12
Fields:
Hem
Hematology
Translation:
Animals
Cells
Mayo LD, Dixon JE,
Durden DL
, Tonks NK, Donner DB. PTEN protects p53 from Mdm2 and sensitizes cancer cells to chemotherapy. J Biol Chem. 2002 Feb 15; 277(7):5484-9.
PMID:
11729185
.
Citations:
97
Fields:
Bio
Biochemistry
Translation:
Humans
Cells
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