Frank L van de Veerdonk

InstitutionRadboud university medical center
AddressThe
Netherlands
vCardDownload vCard
    Publication Timeline
    COVID-19 publications
    Bar chart showing 34 Covid-19 publications, with a maximum of 4 publications in May 2020
    All Publications
    Bar chart showing 161 publications over 14 distinct years, with a maximum of 17 publications in 2014 and 2017 and 2020 and 2021
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

    To see the data from both graphs as text, click here.
    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
    Sort By:     Newest   |   Oldest   |   Most Cited   |   Most Discussed
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Brüggemann RJ, van de Veerdonk FL, Verweij PE. The Challenge of Managing COVID-19 Associated Pulmonary Aspergillosis. Clin Infect Dis. 2021 12 06; 73(11):e3615-e3616. PMID: 32810202.
      Citations: 6     Fields:    Translation:Humans
    2. Goligher EC, Bradbury CA, McVerry BJ, Lawler PR, Berger JS, Gong MN, Carrier M, Reynolds HR, Kumar A, Turgeon AF, Kornblith LZ, Kahn SR, Marshall JC, Kim KS, Houston BL, Derde LPG, Cushman M, Tritschler T, Angus DC, Godoy LC, McQuilten Z, Kirwan BA, Farkouh ME, Brooks MM, Lewis RJ, Berry LR, Lorenzi E, Gordon AC, Ahuja T, Al-Beidh F, Annane D, Arabi YM, Aryal D, Baumann Kreuziger L, Beane A, Bhimani Z, Bihari S, Billett HH, Bond L, Bonten M, Brunkhorst F, Buxton M, Buzgau A, Castellucci LA, Chekuri S, Chen JT, Cheng AC, Chkhikvadze T, Coiffard B, Contreras A, Costantini TW, de Brouwer S, Detry MA, Duggal A, Džavík V, Effron MB, Eng HF, Escobedo J, Estcourt LJ, Everett BM, Fergusson DA, Fitzgerald M, et al. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 26; 385(9):777-789. PMID: 34351722.
      Citations: 59     Fields:    Translation:Humans
    3. Lawler PR, Goligher EC, Berger JS, Neal MD, McVerry BJ, Nicolau JC, Gong MN, Carrier M, Rosenson RS, Reynolds HR, Turgeon AF, Escobedo J, Huang DT, Bradbury CA, Houston BL, Kornblith LZ, Kumar A, Kahn SR, Cushman M, McQuilten Z, Slutsky AS, Kim KS, Gordon AC, Kirwan BA, Brooks MM, Higgins AM, Lewis RJ, Lorenzi E, Berry SM, Berry LR, Aday AW, Al-Beidh F, Annane D, Arabi YM, Aryal D, Baumann Kreuziger L, Beane A, Bhimani Z, Bihari S, Billett HH, Bond L, Bonten M, Brunkhorst F, Buxton M, Buzgau A, Castellucci LA, Chekuri S, Chen JT, Cheng AC, Chkhikvadze T, Coiffard B, Costantini TW, de Brouwer S, Derde LPG, Detry MA, Duggal A, Džavík V, Effron MB, Estcourt LJ, Everett BM, Fergusson DA, Fitzgerald M, et al. Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. N Engl J Med. 2021 Aug 26; 385(9):790-802. PMID: 34351721.
      Citations: 60     Fields:    Translation:Humans
    4. de Nooijer AH, Grondman I, Lambden S, Kooistra EJ, Janssen NAF, Kox M, Pickkers P, Joosten LAB, van de Veerdonk FL, Derive M, Gibot S, Netea MG. Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19. Biosci Rep. 2021 07 30; 41(7). PMID: 34195785.
      Citations: 1     Fields:    Translation:Humans
    5. Solanich X, Vargas-Parra G, van der Made CI, Simons A, Schuurs-Hoeijmakers J, Antolí A, Del Valle J, Rocamora-Blanch G, Setién F, Esteller M, van Reijmersdal SV, Riera-Mestre A, Sabater-Riera J, Capellá G, van de Veerdonk FL, van der Hoven B, Corbella X, Hoischen A, Lázaro C. Genetic Screening for TLR7 Variants in Young and Previously Healthy Men With Severe COVID-19. Front Immunol. 2021; 12:719115. PMID: 34367187.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    6. Verweij PE, Brüggemann RJM, Azoulay E, Bassetti M, Blot S, Buil JB, Calandra T, Chiller T, Clancy CJ, Cornely OA, Depuydt P, Koehler P, Lagrou K, de Lange D, Lass-Flörl C, Lewis RE, Lortholary O, Liu PL, Maertens J, Nguyen MH, Patterson TF, Rijnders BJA, Rodriguez A, Rogers TR, Schouten JA, Wauters J, van de Veerdonk FL, Martin-Loeches I. Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis. Intensive Care Med. 2021 08; 47(8):819-834. PMID: 34160631.
      Citations: 10     Fields:    Translation:Humans
    7. Bulut H, Herbers AHE, Hageman IMG, Netten PM, de Jonge HJM, Joustra R, van de Veerdonk FL, de Jager CPC. SARS-CoV-2-Induced Multisystem Inflammatory Syndrome in a Young Adult: Case Report. SN Compr Clin Med. 2021; 3(8):1773-1779. PMID: 34179694.
      Citations:    
    8. Grondman I, de Nooijer AH, Antonakos N, Janssen NAF, Mouktaroudi M, Leventogiannis K, Medici M, Smit JWA, van Herwaarden AE, Joosten LAB, van de Veerdonk FL, Pickkers P, Kox M, Jaeger M, Netea MG, Giamarellos-Bourboulis EJ, Netea-Maier RT. The Association of TSH and Thyroid Hormones With Lymphopenia in Bacterial Sepsis and COVID-19. J Clin Endocrinol Metab. 2021 06 16; 106(7):1994-2009. PMID: 33713408.
      Citations: 1     Fields:    Translation:Humans
    9. van de Veerdonk FL, Brüggemann RJM, Vos S, De Hertogh G, Wauters J, Reijers MHE, Netea MG, Schouten JA, Verweij PE. COVID-19-associated Aspergillus tracheobronchitis: the interplay between viral tropism, host defence, and fungal invasion. Lancet Respir Med. 2021 07; 9(7):795-802. PMID: 34051176.
      Citations: 11     Fields:    Translation:Humans
    10. Dewi IM, Janssen NA, Rosati D, Bruno M, Netea MG, Brüggemann RJ, Verweij PE, van de Veerdonk FL. Invasive pulmonary aspergillosis associated with viral pneumonitis. Curr Opin Microbiol. 2021 08; 62:21-27. PMID: 34034082.
      Citations: 3     Fields:    Translation:Humans
    11. Citations: 9     Fields:    Translation:HumansCells
    12. van de Veerdonk FL, Netea MG. Rare variants increase the risk of severe COVID-19. Elife. 2021 Mar 23; 10. PMID: 33752797.
      Citations: 2     Fields:    Translation:Humans
    13. Westerouen van Meeteren MJ, Van den Heuvel FM, Weijers G, Joosten LA, De Mast Q, Van de Veerdonk FL, Pickkers P, De Nooijer AH, Hoefsloot W, Drenth JP, De Korte CL, Nijveldt R, Netea MG, Tjwa ET. A limited role of cytokine storm and fibrogenesis in COVID-19 related liver injury. J Gastrointestin Liver Dis. 2021 03 13; 30(1):166-168. PMID: 33723544.
      Citations:    Fields:    Translation:Humans
    14. Gordon AC, Mouncey PR, Al-Beidh F, Rowan KM, Nichol AD, Arabi YM, Annane D, Beane A, van Bentum-Puijk W, Berry LR, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Buzgau A, Cheng AC, Detry MA, Duffy EJ, Estcourt LJ, Fitzgerald M, Goossens H, Haniffa R, Higgins AM, Hills TE, Horvat CM, Lamontagne F, Lawler PR, Leavis HL, Linstrum KM, Litton E, Lorenzi E, Marshall JC, Mayr FB, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Montgomery SK, Morpeth SC, Murthy S, Orr K, Parke RL, Parker JC, Patanwala AE, Pettilä V, Rademaker E, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Sligl WI, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Webb SA, Derde LPG. Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19. N Engl J Med. 2021 04 22; 384(16):1491-1502. PMID: 33631065.
      Citations: 262     Fields:    Translation:Humans
    15. de Nooijer AH, Grondman I, Janssen NAF, Netea MG, Willems L, van de Veerdonk FL, Giamarellos-Bourboulis EJ, Toonen EJM, Joosten LAB. Complement Activation in the Disease Course of Coronavirus Disease 2019 and Its Effects on Clinical Outcomes. J Infect Dis. 2021 02 03; 223(2):214-224. PMID: 33038254.
      Citations: 19     Fields:    Translation:Humans
    16. Kooistra EJ, de Nooijer AH, Claassen WJ, Grondman I, Janssen NAF, Netea MG, van de Veerdonk FL, van der Hoeven JG, Kox M, Pickkers P. A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients. Int J Obes (Lond). 2021 03; 45(3):687-694. PMID: 33495522.
      Citations: 6     Fields:    Translation:Humans
    17. Aschenbrenner AC, Mouktaroudi M, Krämer B, Oestreich M, Antonakos N, Nuesch-Germano M, Gkizeli K, Bonaguro L, Reusch N, Baßler K, Saridaki M, Knoll R, Pecht T, Kapellos TS, Doulou S, Kröger C, Herbert M, Holsten L, Horne A, Gemünd ID, Rovina N, Agrawal S, Dahm K, van Uelft M, Drews A, Lenkeit L, Bruse N, Gerretsen J, Gierlich J, Becker M, Händler K, Kraut M, Theis H, Mengiste S, De Domenico E, Schulte-Schrepping J, Seep L, Raabe J, Hoffmeister C, ToVinh M, Keitel V, Rieke G, Talevi V, Skowasch D, Aziz NA, Pickkers P, van de Veerdonk FL, Netea MG, Schultze JL, Kox M, Breteler MMB, Nattermann J, Koutsoukou A, Giamarellos-Bourboulis EJ, Ulas T. Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients. Genome Med. 2021 01 13; 13(1):7. PMID: 33441124.
      Citations: 38     Fields:    Translation:HumansCells
    18. Kooistra EJ, Waalders NJB, Grondman I, Janssen NAF, de Nooijer AH, Netea MG, van de Veerdonk FL, Ewalds E, van der Hoeven JG, Kox M, Pickkers P. Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study. Crit Care. 2020 12 10; 24(1):688. PMID: 33302991.
      Citations: 25     Fields:    Translation:HumansPHPublic Health
    19. Costantini C, van de Veerdonk FL, Romani L. Covid-19-Associated Pulmonary Aspergillosis: The Other Side of the Coin. Vaccines (Basel). 2020 Dec 01; 8(4). PMID: 33271780.
      Citations: 6     
    20. Buijsers B, Yanginlar C, de Nooijer A, Grondman I, Maciej-Hulme ML, Jonkman I, Janssen NAF, Rother N, de Graaf M, Pickkers P, Kox M, Joosten LAB, Nijenhuis T, Netea MG, Hilbrands L, van de Veerdonk FL, Duivenvoorden R, de Mast Q, van der Vlag J. Increased Plasma Heparanase Activity in COVID-19 Patients. Front Immunol. 2020; 11:575047. PMID: 33123154.
      Citations: 28     Fields:    Translation:HumansCellsPHPublic Health
    21. Armstrong-James D, Youngs J, Bicanic T, Abdolrasouli A, Denning DW, Johnson E, Mehra V, Pagliuca T, Patel B, Rhodes J, Schelenz S, Shah A, van de Veerdonk FL, Verweij PE, White PL, Fisher MC. Confronting and mitigating the risk of COVID-19 associated pulmonary aspergillosis. Eur Respir J. 2020 10; 56(4). PMID: 32703771.
      Citations: 30     Fields:    Translation:HumansCellsPHPublic Health
    22. Beer KD, Jackson BR, Chiller T, Verweij PE, Van de Veerdonk FL, Wauters J. Does Pulmonary Aspergillosis Complicate Coronavirus Disease 2019? Crit Care Explor. 2020 Sep; 2(9):e0211. PMID: 32984834.
      Citations: 5     
    23. Citations: 181     Fields:    Translation:HumansCells
    24. Moorlag SJCFM, van Deuren RC, van Werkhoven CH, Jaeger M, Debisarun P, Taks E, Mourits VP, Koeken VACM, de Bree LCJ, Ten Doesschate T, Cleophas MC, Smeekens S, Oosting M, van de Veerdonk FL, Joosten LAB, Ten Oever J, van der Meer JWM, Curtis N, Aaby P, Stabell-Benn C, Giamarellos-Bourboulis EJ, Bonten M, van Crevel R, Netea MG. Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study. Cell Rep Med. 2020 08 25; 1(5):100073. PMID: 32838341.
      Citations: 22     
    25. van de Veerdonk FL, Kouijzer IJE, de Nooijer AH, van der Hoeven HG, Maas C, Netea MG, Brüggemann RJM. Outcomes Associated With Use of a Kinin B2 Receptor Antagonist Among Patients With COVID-19. JAMA Netw Open. 2020 08 03; 3(8):e2017708. PMID: 32789513.
      Citations: 21     Fields:    Translation:HumansCellsPHPublic Health
    26. van de Veerdonk FL, Netea MG. Blocking IL-1 to prevent respiratory failure in COVID-19. Crit Care. 2020 07 18; 24(1):445. PMID: 32682440.
      Citations: 27     Fields:    Translation:HumansPHPublic Health
    27. Arastehfar A, Carvalho A, van de Veerdonk FL, Jenks JD, Koehler P, Krause R, Cornely OA, S Perlin D, Lass-Flörl C, Hoenigl M. COVID-19 Associated Pulmonary Aspergillosis (CAPA)-From Immunology to Treatment. J Fungi (Basel). 2020 Jun 24; 6(2). PMID: 32599813.
      Citations: 71     
    28. Verweij PE, Rijnders BJA, Brüggemann RJM, Azoulay E, Bassetti M, Blot S, Calandra T, Clancy CJ, Cornely OA, Chiller T, Depuydt P, Giacobbe DR, Janssen NAF, Kullberg BJ, Lagrou K, Lass-Flörl C, Lewis RE, Liu PW, Lortholary O, Maertens J, Martin-Loeches I, Nguyen MH, Patterson TF, Rogers TR, Schouten JA, Spriet I, Vanderbeke L, Wauters J, van de Veerdonk FL. Review of influenza-associated pulmonary aspergillosis in ICU patients and proposal for a case definition: an expert opinion. Intensive Care Med. 2020 Aug; 46(8):1524-1535. PMID: 32572532.
      Citations: 77     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    29. de Maat S, de Mast Q, Danser AHJ, van de Veerdonk FL, Maas C. Impaired Breakdown of Bradykinin and Its Metabolites as a Possible Cause for Pulmonary Edema in COVID-19 Infection. Semin Thromb Hemost. 2020 10; 46(7):835-837. PMID: 32526773.
      Citations: 19     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    30. Kox M, Frenzel T, Schouten J, van de Veerdonk FL, Koenen HJPM, Pickkers P. COVID-19 patients exhibit less pronounced immune suppression compared with bacterial septic shock patients. Crit Care. 2020 May 26; 24(1):263. PMID: 32456696.
      Citations: 11     Fields:    Translation:HumansCellsPHPublic Health
    31. Dimopoulos G, de Mast Q, Markou N, Theodorakopoulou M, Komnos A, Mouktaroudi M, Netea MG, Spyridopoulos T, Verheggen RJ, Hoogerwerf J, Lachana A, van de Veerdonk FL, Giamarellos-Bourboulis EJ. Favorable Anakinra Responses in Severe Covid-19 Patients with Secondary Hemophagocytic Lymphohistiocytosis. Cell Host Microbe. 2020 07 08; 28(1):117-123.e1. PMID: 32411313.
      Citations: 92     Fields:    Translation:HumansCellsPHPublic Health
    32. Verweij PE, Gangneux JP, Bassetti M, Brüggemann RJM, Cornely OA, Koehler P, Lass-Flörl C, van de Veerdonk FL, Chakrabarti A, Hoenigl M. Diagnosing COVID-19-associated pulmonary aspergillosis. Lancet Microbe. 2020 Jun; 1(2):e53-e55. PMID: 32835328.
      Citations: 55     
    33. Netea MG, Giamarellos-Bourboulis EJ, Domínguez-Andrés J, Curtis N, van Crevel R, van de Veerdonk FL, Bonten M. Trained Immunity: a Tool for Reducing Susceptibility to and the Severity of SARS-CoV-2 Infection. Cell. 2020 05 28; 181(5):969-977. PMID: 32437659.
      Citations: 115     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    34. van de Veerdonk FL, Netea MG, van Deuren M, van der Meer JW, de Mast Q, Brüggemann RJ, van der Hoeven H. Kallikrein-kinin blockade in patients with COVID-19 to prevent acute respiratory distress syndrome. Elife. 2020 04 27; 9. PMID: 32338605.
      Citations: 113     Fields:    Translation:HumansCellsPHPublic Health
    35. Wijmenga C, Netea MG, Kumar V, Jaeger M, Matzaraki V, Aguirre-Gamboa R, Gresnigt MS, Chu X, Johnson MD, Oosting M, Smeekens SP, Withoff S, Jonkers I, Perfect JR, van de Veerdonk FL, Kullberg BJ, Joosten LAB, Li Y. A Genome-Wide Functional Genomics Approach Identifies Susceptibility Pathways to Fungal Bloodstream Infection in Humans. J Infect Dis. 2019 07 31; 220(5):862-872. PMID: 31241743.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    36. Campos CF, van de Veerdonk FL, Gonçalves SM, Cunha C, Netea MG, Carvalho A. Host Genetic Signatures of Susceptibility to Fungal Disease. Curr Top Microbiol Immunol. 2019; 422:237-263. PMID: 30043341.
      Citations: 6     Fields:    Translation:HumansAnimals
    37. Niehues H, Rösler B, van der Krieken DA, van Vlijmen-Willems IMJJ, Rodijk-Olthuis D, Peppelman M, Schalkwijk J, van den Bogaard EHJ, Zeeuwen PLJM, van de Veerdonk FL. STAT1 gain-of-function compromises skin host defense in the context of IFN-? signaling. J Allergy Clin Immunol. 2019 04; 143(4):1626-1629.e5. PMID: 30576757.
      Citations: 3     Fields:    Translation:HumansCells
    38. Schauwvlieghe AFAD, Rijnders BJA, Philips N, Verwijs R, Vanderbeke L, Van Tienen C, Lagrou K, Verweij PE, Van de Veerdonk FL, Gommers D, Spronk P, Bergmans DCJJ, Hoedemaekers A, Andrinopoulou ER, van den Berg CHSB, Juffermans NP, Hodiamont CJ, Vonk AG, Depuydt P, Boelens J, Wauters J. Invasive aspergillosis in patients admitted to the intensive care unit with severe influenza: a retrospective cohort study. Lancet Respir Med. 2018 10; 6(10):782-792. PMID: 30076119.
      Citations: 201     Fields:    Translation:HumansAnimalsCells
    39. Gresnigt MS, Cunha C, Jaeger M, Gonçalves SM, Malireddi RKS, Ammerdorffer A, Lubbers R, Oosting M, Rasid O, Jouvion G, Fitting C, Jong DJ, Lacerda JF, Campos A, Melchers WJG, Lagrou K, Maertens J, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL. Genetic deficiency of NOD2 confers resistance to invasive aspergillosis. Nat Commun. 2018 07 06; 9(1):2636. PMID: 29980664.
      Citations: 18     Fields:    Translation:HumansAnimals
    40. Vreugdenhil B, van der Velden WJFM, Feuth T, Kox M, Pickkers P, van de Veerdonk FL, Blijlevens NMA, Brüggemann RJM. Moderate correlation between systemic IL-6 responses and CRP with trough concentrations of voriconazole. Br J Clin Pharmacol. 2018 09; 84(9):1980-1988. PMID: 29744898.
      Citations: 9     Fields:    Translation:Humans
    41. Kumar V, van de Veerdonk FL, Netea MG. Antifungal immune responses: emerging host-pathogen interactions and translational implications. Genome Med. 2018 05 25; 10(1):39. PMID: 29801518.
      Citations: 3     Fields:    Translation:HumansAnimals
    42. Workum JD, de Jong SW, Gresnigt MS, Becker KL, Pickkers P, van de Veerdonk FL, Heijdra YF, Kolwijck E. Microbiological and immunological characteristics of a lethal pulmonary Aspergillus niger infection in a non-neutropenic patient. Med Mycol Case Rep. 2018 Sep; 21:4-7. PMID: 29984147.
      Citations: 2     
    43. Bekkering S, Arts RJW, Novakovic B, Kourtzelis I, van der Heijden CDCC, Li Y, Popa CD, Ter Horst R, van Tuijl J, Netea-Maier RT, van de Veerdonk FL, Chavakis T, Joosten LAB, van der Meer JWM, Stunnenberg H, Riksen NP, Netea MG. Metabolic Induction of Trained Immunity through the Mevalonate Pathway. Cell. 2018 01 11; 172(1-2):135-146.e9. PMID: 29328908.
      Citations: 156     Fields:    Translation:HumansAnimalsCells
    44. van de Veerdonk FL, de Graaf DM, Joosten LA, Dinarello CA. Biology of IL-38 and its role in disease. Immunol Rev. 2018 01; 281(1):191-196. PMID: 29247986.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    45. van der Poll T, van de Veerdonk FL, Scicluna BP, Netea MG. Are histones real pathogenic agents in sepsis? Nat Rev Immunol. 2018 02; 18(2):148. PMID: 29279614.
      Citations: 1     Fields:    Translation:Humans
    46. Gresnigt MS, Jaeger M, Subbarao Malireddi RK, Rasid O, Jouvion G, Fitting C, Melchers WJG, Kanneganti TD, Carvalho A, Ibrahim-Granet O, van de Veerdonk FL. The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression. Front Immunol. 2017; 8:1777. PMID: 29326692.
      Citations: 5     Fields:    
    47. Koch RM, Kox M, Thijs EJM, Rahamat-Langendoen JC, van de Veerdonk FL, Gerretsen J, Schloesser J, Diavatopoulos D, Rimmelzwaan GF, Netea MG, van der Hoeven JG, de Jonge MI, Pickkers P. Development of Endotoxin Tolerance Does Not Influence the Response to a Challenge with the Mucosal Live-Attenuated Influenza Vaccine in Humans In Vivo. Front Immunol. 2017; 8:1600. PMID: 29312282.
      Citations: 7     Fields:    
    48. Desai JV, van de Veerdonk FL, Lionakis MS. Understanding the role of host immune responses in invasive candidiasis. Intensive Care Med. 2018 08; 44(8):1310-1314. PMID: 29167916.
      Citations: 6     Fields:    Translation:Humans
    49. Brüggemann RJ, van de Veerdonk FL, Verweij PE. Itraconazole or Amphotericin B for Talaromycosis. N Engl J Med. 2017 10 05; 377(14):1402-1403. PMID: 28976857.
      Citations:    Fields:    
    50. Dewi IMW, van de Veerdonk FL, Gresnigt MS. The Multifaceted Role of T-Helper Responses in Host Defense against Aspergillus fumigatus. J Fungi (Basel). 2017 Oct 04; 3(4). PMID: 29371571.
      Citations: 17     
    51. Aleva FE, van de Veerdonk FL, Li Y, Tunjungputri RN, Simons S, De Groot PG, Netea MM, Heijdra YF, de Mast Q, van der Ven AJAM. The effects of signal transducer and activator of transcription three mutations on human platelets. Platelets. 2018 Sep; 29(6):602-609. PMID: 28960117.
      Citations: 1     Fields:    Translation:HumansCells
    52. Zimmerman O, Rösler B, Zerbe CS, Rosen LB, Hsu AP, Uzel G, Freeman AF, Sampaio EP, Rosenzweig SD, Kuehn HS, Kim T, Brooks KM, Kumar P, Wang X, Netea MG, van de Veerdonk FL, Holland SM. Risks of Ruxolitinib in STAT1 Gain-of-Function-Associated Severe Fungal Disease. Open Forum Infect Dis. 2017; 4(4):ofx202. PMID: 29226168.
      Citations: 13     
    53. Domínguez-Andrés J, Arts RJW, Ter Horst R, Gresnigt MS, Smeekens SP, Ratter JM, Lachmandas E, Boutens L, van de Veerdonk FL, Joosten LAB, Notebaart RA, Ardavín C, Netea MG. Rewiring monocyte glucose metabolism via C-type lectin signaling protects against disseminated candidiasis. PLoS Pathog. 2017 Sep; 13(9):e1006632. PMID: 28922415.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    54. Raijmakers RPH, Sprenkeler EGG, Aleva FE, Jacobs CWM, Kanneganti TD, Joosten LAB, van de Veerdonk FL, Gresnigt MS. Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics. Sci Rep. 2017 09 13; 7(1):11500. PMID: 28904353.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    55. Matzaraki V, Gresnigt MS, Jaeger M, Ricaño-Ponce I, Johnson MD, Oosting M, Franke L, Withoff S, Perfect JR, Joosten LAB, Kullberg BJ, van de Veerdonk FL, Jonkers I, Li Y, Wijmenga C, Netea MG, Kumar V. An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility. PLoS One. 2017; 12(7):e0180824. PMID: 28727728.
      Citations: 12     Fields:    Translation:HumansCells
    56. Crisan TO, Cleophas MCP, Novakovic B, Erler K, van de Veerdonk FL, Stunnenberg HG, Netea MG, Dinarello CA, Joosten LAB. Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway. Proc Natl Acad Sci U S A. 2017 05 23; 114(21):5485-5490. PMID: 28484006.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    57. van de Veerdonk FL, Gresnigt MS, Verweij PE, Netea MG. Personalized medicine in influenza: a bridge too far or the near future? Curr Opin Pulm Med. 2017 05; 23(3):237-240. PMID: 28257314.
      Citations: 2     Fields:    Translation:Humans
    58. van der Poll T, van de Veerdonk FL, Scicluna BP, Netea MG. The immunopathology of sepsis and potential therapeutic targets. Nat Rev Immunol. 2017 Jul; 17(7):407-420. PMID: 28436424.
      Citations: 325     Fields:    Translation:HumansAnimalsCells
    59. van de Veerdonk FL, Kolwijck E, Lestrade PP, Hodiamont CJ, Rijnders BJ, van Paassen J, Haas PJ, Oliveira Dos Santos C, Kampinga GA, Bergmans DC, van Dijk K, de Haan AF, van Dissel J, van der Hoeven HG, Verweij PE. Influenza-Associated Aspergillosis in Critically Ill Patients. Am J Respir Crit Care Med. 2017 08 15; 196(4):524-527. PMID: 28387526.
      Citations: 58     Fields:    
    60. Leentjens J, Gresnigt MS, van de Veerdonk FL, Kox M, Kullberg BJ, Pickkers P, Brouwer AE, Netea MG. Adjuvant interferon-gamma immunotherapy in a patient with progressive cerebral Nocardia abscesses. Int J Infect Dis. 2017 Jun; 59:25-28. PMID: 28342802.
      Citations: 3     Fields:    Translation:HumansCells
    61. Becker KL, Arts P, Jaeger M, Plantinga TS, Gilissen C, van Laarhoven A, van Ingen J, Veltman JA, Joosten LA, Hoischen A, Netea MG, Iseman MD, Chan ED, van de Veerdonk FL. MST1R mutation as a genetic cause of Lady Windermere syndrome. Eur Respir J. 2017 01; 49(1). PMID: 28100548.
      Citations: 5     Fields:    Translation:HumansCells
    62. Slaats J, Ten Oever J, van de Veerdonk FL, Netea MG. IL-1ß/IL-6/CRP and IL-18/ferritin: Distinct Inflammatory Programs in Infections. PLoS Pathog. 2016 Dec; 12(12):e1005973. PMID: 27977798.
      Citations: 70     Fields:    Translation:HumansAnimals
    63. Donker AE, Schaap CC, Novotny VM, Smeets R, Peters TM, van den Heuvel BL, Raphael MF, Rijneveld AW, Appel IM, Vlot AJ, Versluijs AB, van Gelder M, Granzen B, Janssen MC, Rennings AJ, van de Veerdonk FL, Brons PP, Bakkeren DL, Nijziel MR, Vlasveld LT, Swinkels DW. Iron refractory iron deficiency anemia: a heterogeneous disease that is not always iron refractory. Am J Hematol. 2016 12; 91(12):E482-E490. PMID: 27643674.
      Citations: 3     Fields:    Translation:Humans
    64. Arts RJ, Novakovic B, Ter Horst R, Carvalho A, Bekkering S, Lachmandas E, Rodrigues F, Silvestre R, Cheng SC, Wang SY, Habibi E, Gonçalves LG, Mesquita I, Cunha C, van Laarhoven A, van de Veerdonk FL, Williams DL, van der Meer JW, Logie C, O'Neill LA, Dinarello CA, Riksen NP, van Crevel R, Clish C, Notebaart RA, Joosten LA, Stunnenberg HG, Xavier RJ, Netea MG. Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity. Cell Metab. 2016 12 13; 24(6):807-819. PMID: 27866838.
      Citations: 199     Fields:    Translation:HumansCells
    65. Wang X, Zhang R, Wu W, Wang A, Wan Z, van de Veerdonk FL, Li R. New and recurrent STAT1 mutations in seven Chinese patients with chronic mucocutaneous candidiasis. Int J Dermatol. 2017 Feb; 56(2):e30-e33. PMID: 27808400.
      Citations: 3     Fields:    Translation:Humans
    66. Verweij PE, Zhang J, Debets AJM, Meis JF, van de Veerdonk FL, Schoustra SE, Zwaan BJ, Melchers WJG. In-host adaptation and acquired triazole resistance in Aspergillus fumigatus: a dilemma for clinical management. Lancet Infect Dis. 2016 Nov; 16(11):e251-e260. PMID: 27638360.
      Citations: 48     Fields:    Translation:HumansAnimals
    67. van de Veerdonk FL, Netea MG. CBLB ubiquitin ligase: a major regulator of antifungal immunity. Nat Med. 2016 08 04; 22(8):834-5. PMID: 27490434.
      Citations: 1     Fields:    Translation:Humans
    68. Sprenkeler EG, Gresnigt MS, van de Veerdonk FL. LC3-associated phagocytosis: a crucial mechanism for antifungal host defence against Aspergillus fumigatus. Cell Microbiol. 2016 09; 18(9):1208-16. PMID: 27185357.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    69. Gresnigt MS, Rekiki A, Rasid O, Savers A, Jouvion G, Dannaoui E, Parlato M, Fitting C, Brock M, Cavaillon JM, van de Veerdonk FL, Ibrahim-Granet O. Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor. Sci Rep. 2016 05 24; 6:26490. PMID: 27215684.
      Citations: 17     Fields:    Translation:Animals
    70. van de Veerdonk FL, Netea MG. Treatment options for chronic mucocutaneous candidiasis. J Infect. 2016 07 05; 72 Suppl:S56-60. PMID: 27161991.
      Citations: 9     Fields:    Translation:HumansCells
    71. Arts P, van de Veerdonk FL, van der Lee R, Langereis MA, Gilissen C, van Zelst-Stams WAG, Huynen MA, van der Meer JWM, van Kuppeveld FJ, Veltman JA, Kullberg BJ, Hoischen A, Netea MG. Immunologic defects in severe mucocutaneous HSV-2 infections: Response to IFN-? therapy. J Allergy Clin Immunol. 2016 09; 138(3):895-898. PMID: 27132219.
      Citations: 2     Fields:    Translation:HumansCells
    72. Iannitti RG, Napolioni V, Oikonomou V, De Luca A, Galosi C, Pariano M, Massi-Benedetti C, Borghi M, Puccetti M, Lucidi V, Colombo C, Fiscarelli E, Lass-Flörl C, Majo F, Cariani L, Russo M, Porcaro L, Ricciotti G, Ellemunter H, Ratclif L, De Benedictis FM, Talesa VN, Dinarello CA, van de Veerdonk FL, Romani L. IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis. Nat Commun. 2016 Mar 14; 7:10791. PMID: 26972847.
      Citations: 88     Fields:    Translation:HumansAnimalsCells
    73. Cheng SC, Scicluna BP, Arts RJ, Gresnigt MS, Lachmandas E, Giamarellos-Bourboulis EJ, Kox M, Manjeri GR, Wagenaars JA, Cremer OL, Leentjens J, van der Meer AJ, van de Veerdonk FL, Bonten MJ, Schultz MJ, Willems PH, Pickkers P, Joosten LA, van der Poll T, Netea MG. Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis. Nat Immunol. 2016 Apr; 17(4):406-13. PMID: 26950237.
      Citations: 151     Fields:    Translation:HumansAnimalsCells
    74. Wang X, van de Veerdonk FL, Netea MG. Basic Genetics and Immunology of Candida Infections. Infect Dis Clin North Am. 2016 Mar; 30(1):85-102. PMID: 26897063.
      Citations: 13     Fields:    Translation:HumansAnimals
    75. Wang X, van de Veerdonk FL. When the Fight against Fungi Goes Wrong. PLoS Pathog. 2016 Feb; 12(2):e1005400. PMID: 26845151.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    76. van der Kolk NM, Arts P, van Uden IW, Hoischen A, van de Veerdonk FL, Netea MG, de Jong BA. Progressive multifocal leukoencephalopathy in an immunocompetent patient. Ann Clin Transl Neurol. 2016 03; 3(3):226-32. PMID: 27042682.
      Citations: 7     Fields:    
    77. Becker KL, van Ingen J, Ten Oever J, Merkus PJ, Ferwerda G, Netea MG, Magis-Escurra C, Reijers MH, van de Veerdonk FL. Deficient interleukin-17 production in response to Mycobacterium abscessus in cystic fibrosis. Eur Respir J. 2016 Mar; 47(3):990-3. PMID: 26743483.
      Citations: 6     Fields:    Translation:HumansCells
    78. Akoumianaki T, Kyrmizi I, Valsecchi I, Gresnigt MS, Samonis G, Drakos E, Boumpas D, Muszkieta L, Prevost MC, Kontoyiannis DP, Chavakis T, Netea MG, van de Veerdonk FL, Brakhage AA, El-Benna J, Beauvais A, Latge JP, Chamilos G. Aspergillus Cell Wall Melanin Blocks LC3-Associated Phagocytosis to Promote Pathogenicity. Cell Host Microbe. 2016 Jan 13; 19(1):79-90. PMID: 26749442.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    79. Gazendam RP, van Hamme JL, Tool AT, Hoogenboezem M, van den Berg JM, Prins JM, Vitkov L, van de Veerdonk FL, van den Berg TK, Roos D, Kuijpers TW. Human Neutrophils Use Different Mechanisms To Kill Aspergillus fumigatus Conidia and Hyphae: Evidence from Phagocyte Defects. J Immunol. 2016 Feb 01; 196(3):1272-83. PMID: 26718340.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    80. Netea MG, Joosten LA, van der Meer JW, Kullberg BJ, van de Veerdonk FL. Immune defence against Candida fungal infections. Nat Rev Immunol. 2015 Oct; 15(10):630-42. PMID: 26388329.
      Citations: 147     Fields:    Translation:HumansAnimals
    81. Zheng J, van de Veerdonk FL, Crossland KL, Smeekens SP, Chan CM, Al Shehri T, Abinun M, Gennery AR, Mann J, Lendrem DW, Netea MG, Rowan AD, Lilic D. Gain-of-function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC). Eur J Immunol. 2015 Oct; 45(10):2834-46. PMID: 26255980.
      Citations: 44     Fields:    Translation:HumansCellsCTClinical Trials
    82. Oosting M, Buffen K, Cheng SC, Verschueren IC, Koentgen F, van de Veerdonk FL, Netea MG, Joosten LAB. Borrelia-induced cytokine production is mediated by spleen tyrosine kinase (Syk) but is Dectin-1 and Dectin-2 independent. Cytokine. 2015 Dec; 76(2):465-472. PMID: 26297607.
      Citations: 8     Fields:    Translation:AnimalsCells
    83. Borghi M, De Luca A, Puccetti M, Jaeger M, Mencacci A, Oikonomou V, Pariano M, Garlanda C, Moretti S, Bartoli A, Sobel J, van de Veerdonk FL, Dinarello CA, Netea MG, Romani L. Pathogenic NLRP3 Inflammasome Activity during Candida Infection Is Negatively Regulated by IL-22 via Activation of NLRC4 and IL-1Ra. Cell Host Microbe. 2015 Aug 12; 18(2):198-209. PMID: 26269955.
      Citations: 40     Translation:HumansAnimals
    84. Netea-Maier RT, Plantinga TS, van de Veerdonk FL, Smit JW, Netea MG. Modulation of inflammation by autophagy: Consequences for human disease. Autophagy. 2016; 12(2):245-60. PMID: 26222012.
      Citations: 104     Fields:    Translation:HumansAnimals
    85. Joosten LA, Crisan TO, Azam T, Cleophas MC, Koenders MI, van de Veerdonk FL, Netea MG, Kim S, Dinarello CA. Alpha-1-anti-trypsin-Fc fusion protein ameliorates gouty arthritis by reducing release and extracellular processing of IL-1ß and by the induction of endogenous IL-1Ra. Ann Rheum Dis. 2016 06; 75(6):1219-27. PMID: 26174021.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    86. Kanni T, Tzanetakou V, Savva A, Kersten B, Pistiki A, van de Veerdonk FL, Netea MG, van der Meer JW, Giamarellos-Bourboulis EJ. Compartmentalized Cytokine Responses in Hidradenitis Suppurativa. PLoS One. 2015; 10(6):e0130522. PMID: 26091259.
      Citations: 14     Fields:    Translation:HumansCells
    87. van de Veerdonk FL, Koenen HJ, van der Velden WJ, van der Meer JW, Netea MG. Immunotherapy with G-CSF in patients with chronic mucocutaneous candidiasis. Immunol Lett. 2015 Sep; 167(1):54-6. PMID: 25999307.
      Citations: 5     Fields:    Translation:Humans
    88. Netea MG, van de Veerdonk FL. TREML4 adds fuel to the TLR7 fire. Nat Immunol. 2015 May; 16(5):445-6. PMID: 25898191.
      Citations:    Fields:    Translation:HumansAnimalsCells
    89. van de Veerdonk FL, Joosten LA, Netea MG. The interplay between inflammasome activation and antifungal host defense. Immunol Rev. 2015 May; 265(1):172-80. PMID: 25879292.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    90. van de Veerdonk FL, Netea MG, van der Meer JW. Case 39-2014: A girl with Crohn's disease and pulmonary nodules. N Engl J Med. 2015 03 26; 372(13):1272-3. PMID: 25806933.
      Citations:    Fields:    Translation:Humans
    91. Tunjungputri RN, van der Ven AJ, Riksen N, Rongen G, Tacke S, van den Berg TN, Fijnheer R, Gomes ME, Dinarello CA, van de Veerdonk FL, Gasem MH, Netea MG, Joosten LA, de Groot PG, de Mast Q. Differential effects of platelets and platelet inhibition by ticagrelor on TLR2- and TLR4-mediated inflammatory responses. Thromb Haemost. 2015 May; 113(5):1035-45. PMID: 25716539.
      Citations: 15     Fields:    Translation:HumansCells
    92. Jaeger M, van der Lee R, Cheng SC, Johnson MD, Kumar V, Ng A, Plantinga TS, Smeekens SP, Oosting M, Wang X, Barchet W, Fitzgerald K, Joosten LAB, Perfect JR, Wijmenga C, van de Veerdonk FL, Huynen MA, Xavier RJ, Kullberg BJ, Netea MG. The RIG-I-like helicase receptor MDA5 (IFIH1) is involved in the host defense against Candida infections. Eur J Clin Microbiol Infect Dis. 2015 May; 34(5):963-974. PMID: 25579795.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    93. van de Veerdonk FL, Gresnigt MS, Oosting M, van der Meer JW, Joosten LA, Netea MG, Dinarello CA. Protective host defense against disseminated candidiasis is impaired in mice expressing human interleukin-37. Front Microbiol. 2014; 5:762. PMID: 25620965.
      Citations: 11     
    94. Becker KL, Ifrim DC, Quintin J, Netea MG, van de Veerdonk FL. Antifungal innate immunity: recognition and inflammatory networks. Semin Immunopathol. 2015 Mar; 37(2):107-16. PMID: 25527294.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    95. Netea MG, van de Veerdonk FL, van der Meer JW, Dinarello CA, Joosten LA. Inflammasome-independent regulation of IL-1-family cytokines. Annu Rev Immunol. 2015; 33:49-77. PMID: 25493334.
      Citations: 117     Fields:    Translation:HumansAnimals
    96. Smeekens SP, Gresnigt MS, Becker KL, Cheng SC, Netea SA, Jacobs L, Jansen T, van de Veerdonk FL, Williams DL, Joosten LA, Dinarello CA, Netea MG. An anti-inflammatory property of Candida albicans ß-glucan: Induction of high levels of interleukin-1 receptor antagonist via a Dectin-1/CR3 independent mechanism. Cytokine. 2015 Feb; 71(2):215-22. PMID: 25461401.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    97. Ten Oever J, Kox M, van de Veerdonk FL, Mothapo KM, Slavcovici A, Jansen TL, Tweehuysen L, Giamarellos-Bourboulis EJ, Schneeberger PM, Wever PC, Stoffels M, Simon A, van der Meer JW, Johnson MD, Kullberg BJ, Pickkers P, Pachot A, Joosten LA, Netea MG. The discriminative capacity of soluble Toll-like receptor (sTLR)2 and sTLR4 in inflammatory diseases. BMC Immunol. 2014 Nov 19; 15:55. PMID: 25406630.
      Citations: 21     Fields:    Translation:HumansCells
    98. Wójtowicz A, Gresnigt MS, Lecompte T, Bibert S, Manuel O, Joosten LA, Rüeger S, Berger C, Boggian K, Cusini A, Garzoni C, Hirsch HH, Weisser M, Mueller NJ, Meylan PR, Steiger J, Kutalik Z, Pascual M, van Delden C, van de Veerdonk FL, Bochud PY. IL1B and DEFB1 Polymorphisms Increase Susceptibility to Invasive Mold Infection After Solid-Organ Transplantation. J Infect Dis. 2015 May 15; 211(10):1646-57. PMID: 25398456.
      Citations: 18     Fields:    Translation:HumansAnimals
    99. Moretti S, Bozza S, Oikonomou V, Renga G, Casagrande A, Iannitti RG, Puccetti M, Garlanda C, Kim S, Li S, van de Veerdonk FL, Dinarello CA, Romani L. IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis. PLoS Pathog. 2014 Nov; 10(11):e1004462. PMID: 25375146.
      Citations: 65     Fields:    Translation:Animals
    100. Buffen K, Oosting M, Quintin J, Ng A, Kleinnijenhuis J, Kumar V, van de Vosse E, Wijmenga C, van Crevel R, Oosterwijk E, Grotenhuis AJ, Vermeulen SH, Kiemeney LA, van de Veerdonk FL, Chamilos G, Xavier RJ, van der Meer JW, Netea MG, Joosten LA. Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer. PLoS Pathog. 2014 Oct; 10(10):e1004485. PMID: 25356988.
      Citations: 60     Fields:    Translation:HumansCellsPHPublic Health
    101. Kolwijck E, van de Veerdonk FL. The potential impact of the pulmonary microbiome on immunopathogenesis of Aspergillus-related lung disease. Eur J Immunol. 2014 Nov; 44(11):3156-65. PMID: 25256637.
      Citations: 19     Fields:    Translation:HumansAnimals
    102. Cheng SC, Quintin J, Cramer RA, Shepardson KM, Saeed S, Kumar V, Giamarellos-Bourboulis EJ, Martens JH, Rao NA, Aghajanirefah A, Manjeri GR, Li Y, Ifrim DC, Arts RJ, van der Veer BM, van der Meer BM, Deen PM, Logie C, O'Neill LA, Willems P, van de Veerdonk FL, van der Meer JW, Ng A, Joosten LA, Wijmenga C, Stunnenberg HG, Xavier RJ, Netea MG. mTOR- and HIF-1a-mediated aerobic glycolysis as metabolic basis for trained immunity. Science. 2014 Sep 26; 345(6204):1250684. PMID: 25258083.
      Citations: 554     Fields:    Translation:HumansAnimalsCells
    103. Kumar V, Cheng SC, Johnson MD, Smeekens SP, Wojtowicz A, Giamarellos-Bourboulis E, Karjalainen J, Franke L, Withoff S, Plantinga TS, van de Veerdonk FL, van der Meer JWM, Joosten LAB, Bochud PY, Marchetti O, Perfect JR, Xavier R, Kullberg BJ, Wijmenga C, Netea MG. Immunochip SNP array identifies novel genetic variants conferring susceptibility to candidaemia. Nat Commun. 2014 Sep 08; 5:4675. PMID: 25197941.
      Citations: 37     Fields:    Translation:Humans
    104. Gresnigt MS, van de Veerdonk FL. The role of interleukin-1 family members in the host defence against Aspergillus fumigatus. Mycopathologia. 2014 Dec; 178(5-6):395-401. PMID: 25048411.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    105. Gazendam RP, van Hamme JL, Tool AT, van Houdt M, Verkuijlen PJ, Herbst M, Liese JG, van de Veerdonk FL, Roos D, van den Berg TK, Kuijpers TW. Two independent killing mechanisms of Candida albicans by human neutrophils: evidence from innate immunity defects. Blood. 2014 Jul 24; 124(4):590-7. PMID: 24948657.
      Citations: 66     Fields:    Translation:HumansAnimalsCells
    106. van de Veerdonk FL, Dinarello CA. Deficient autophagy unravels the ROS paradox in chronic granulomatous disease. Autophagy. 2014 Jun; 10(6):1141-2. PMID: 24879159.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    107. Ten Oever J, van de Veerdonk FL, Joosten LA, Simon A, van Crevel R, Kullberg BJ, Gyssens IC, van der Meer JW, van Deuren M, Netea MG. Cytokine production assays reveal discriminatory immune defects in adults with recurrent infections and noninfectious inflammation. Clin Vaccine Immunol. 2014 Aug; 21(8):1061-9. PMID: 24872512.
      Citations: 2     Fields:    Translation:HumansCells
    108. Delsing CE, Gresnigt MS, Leentjens J, Preijers F, Frager FA, Kox M, Monneret G, Venet F, Bleeker-Rovers CP, van de Veerdonk FL, Pickkers P, Pachot A, Kullberg BJ, Netea MG. Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series. BMC Infect Dis. 2014 Mar 26; 14:166. PMID: 24669841.
      Citations: 63     Fields:    Translation:HumansCTClinical Trials
    109. Gresnigt MS, Bozza S, Becker KL, Joosten LA, Abdollahi-Roodsaz S, van der Berg WB, Dinarello CA, Netea MG, Fontaine T, De Luca A, Moretti S, Romani L, Latge JP, van de Veerdonk FL. A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist. PLoS Pathog. 2014 Mar; 10(3):e1003936. PMID: 24603878.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    110. de Luca A, Smeekens SP, Casagrande A, Iannitti R, Conway KL, Gresnigt MS, Begun J, Plantinga TS, Joosten LA, van der Meer JW, Chamilos G, Netea MG, Xavier RJ, Dinarello CA, Romani L, van de Veerdonk FL. IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans. Proc Natl Acad Sci U S A. 2014 Mar 04; 111(9):3526-31. PMID: 24550444.
      Citations: 142     Fields:    Translation:HumansAnimalsCells
    111. Gresnigt MS, van de Veerdonk FL. Biology of IL-36 cytokines and their role in disease. Semin Immunol. 2013 Dec 15; 25(6):458-65. PMID: 24355486.
      Citations: 61     Fields:    Translation:HumansCells
    112. van de Veerdonk FL, Netea MG. New Insights in the Immunobiology of IL-1 Family Members. Front Immunol. 2013; 4:167. PMID: 23847614.
      Citations: 63     Fields:    
    113. Kyrmizi I, Gresnigt MS, Akoumianaki T, Samonis G, Sidiropoulos P, Boumpas D, Netea MG, van de Veerdonk FL, Kontoyiannis DP, Chamilos G. Corticosteroids block autophagy protein recruitment in Aspergillus fumigatus phagosomes via targeting dectin-1/Syk kinase signaling. J Immunol. 2013 Aug 01; 191(3):1287-99. PMID: 23817424.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    114. Smeekens SP, van den Hoogen MW, Kamburova EG, van de Veerdonk FL, Joosten I, Koenen HJ, Netea MG, Hilbrands LB, Joosten LA. The effects of in vivo B-cell depleting therapy on ex-vivo cytokine production. Transpl Immunol. 2013 Jun; 28(4):183-8. PMID: 23651756.
      Citations: 3     Fields:    Translation:HumansCells
    115. Gresnigt MS, Becker KL, Smeekens SP, Jacobs CW, Joosten LA, van der Meer JW, Netea MG, van de Veerdonk FL. Aspergillus fumigatus-induced IL-22 is not restricted to a specific Th cell subset and is dependent on complement receptor 3. J Immunol. 2013 Jun 01; 190(11):5629-39. PMID: 23645883.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    116. Smeekens SP, van de Veerdonk FL, Kullberg BJ, Netea MG. Genetic susceptibility to Candida infections. EMBO Mol Med. 2013 Jun; 5(6):805-13. PMID: 23629947.
      Citations: 49     Fields:    Translation:HumansAnimals
    117. Buffen K, Oosting M, Mennens S, Anand PK, Plantinga TS, Sturm P, van de Veerdonk FL, van der Meer JWM, Xavier RJ, Kanneganti TD, Netea MG, Joosten LAB. Autophagy modulates Borrelia burgdorferi-induced production of interleukin-1ß (IL-1ß). J Biol Chem. 2013 Mar 22; 288(12):8658-8666. PMID: 23386602.
      Citations: 10     Fields:    Translation:HumansCells
    118. Gresnigt MS, Rösler B, Jacobs CW, Becker KL, Joosten LA, van der Meer JW, Netea MG, Dinarello CA, van de Veerdonk FL. The IL-36 receptor pathway regulates Aspergillus fumigatus-induced Th1 and Th17 responses. Eur J Immunol. 2013 Feb; 43(2):416-26. PMID: 23147407.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    119. Gresnigt MS, Netea MG, van de Veerdonk FL. Pattern recognition receptors and their role in invasive aspergillosis. Ann N Y Acad Sci. 2012 Dec; 1273:60-7. PMID: 23230838.
      Citations: 14     Fields:    Translation:HumansAnimals
    120. Oosting M, Buffen K, Malireddi SR, Sturm P, Verschueren I, Koenders MI, van de Veerdonk FL, van der Meer JW, Netea MG, Kanneganti TD, Joosten LA. Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3. Arthritis Res Ther. 2012 Nov 13; 14(6):R247. PMID: 23148704.
      Citations: 9     Fields:    Translation:AnimalsCells
    121. Gresnigt MS, Joosten LA, Verschueren I, van der Meer JW, Netea MG, Dinarello CA, van de Veerdonk FL. Neutrophil-mediated inhibition of proinflammatory cytokine responses. J Immunol. 2012 Nov 15; 189(10):4806-15. PMID: 23053514.
      Citations: 29     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    122. van de Veerdonk FL, Mouktaroudi M, Ramakers BP, Pistiki A, Pickkers P, van der Meer JW, Netea MG, Giamarellos-Bourboulis EJ. Deficient Candida-specific T-helper 17 response during sepsis. J Infect Dis. 2012 Dec 01; 206(11):1798-802. PMID: 22984119.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    123. ten Oever J, Tromp M, Bleeker-Rovers CP, Joosten LA, Netea MG, Pickkers P, van de Veerdonk FL. Combination of biomarkers for the discrimination between bacterial and viral lower respiratory tract infections. J Infect. 2012 Dec; 65(6):490-5. PMID: 22898387.
      Citations: 14     Fields:    Translation:Humans
    124. Marijnissen RJ, Koenders MI, van de Veerdonk FL, Dulos J, Netea MG, Boots AM, Joosten LA, van den Berg WB. Exposure to Candida albicans polarizes a T-cell driven arthritis model towards Th17 responses, resulting in a more destructive arthritis. PLoS One. 2012; 7(6):e38889. PMID: 22719976.
      Citations: 6     Fields:    Translation:AnimalsCells
    125. van de Veerdonk FL, Wever PC, Hermans MH, Fijnheer R, Joosten LA, van der Meer JW, Netea MG, Schneeberger PM. IL-18 serum concentration is markedly elevated in acute EBV infection and can serve as a marker for disease severity. J Infect Dis. 2012 Jul 15; 206(2):197-201. PMID: 22689912.
      Citations: 12     Fields:    Translation:HumansCells
    126. van de Veerdonk FL, Stoeckman AK, Wu G, Boeckermann AN, Azam T, Netea MG, Joosten LA, van der Meer JW, Hao R, Kalabokis V, Dinarello CA. IL-38 binds to the IL-36 receptor and has biological effects on immune cells similar to IL-36 receptor antagonist. Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8):3001-5. PMID: 22315422.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    127. Smeekens SP, Henriet SS, Gresnigt MS, Joosten LA, Hermans PW, Netea MG, Warris A, van de Veerdonk FL. Low interleukin-17A production in response to fungal pathogens in patients with chronic granulomatous disease. J Interferon Cytokine Res. 2012 Apr; 32(4):159-68. PMID: 22191467.
      Citations: 7     Fields:    Translation:HumansAnimals
    128. Smeekens SP, Plantinga TS, van de Veerdonk FL, Heinhuis B, Hoischen A, Joosten LA, Arkwright PD, Gennery A, Kullberg BJ, Veltman JA, Lilic D, van der Meer JW, Netea MG. STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis. PLoS One. 2011; 6(12):e29248. PMID: 22195034.
      Citations: 48     Fields:    Translation:HumansCells
    129. Gow NA, van de Veerdonk FL, Brown AJ, Netea MG. Candida albicans morphogenesis and host defence: discriminating invasion from colonization. Nat Rev Microbiol. 2011 Dec 12; 10(2):112-22. PMID: 22158429.
      Citations: 271     Fields:    Translation:HumansAnimalsCells
    130. Oosting M, ter Hofstede H, van de Veerdonk FL, Sturm P, Kullberg BJ, van der Meer JW, Netea MG, Joosten LA. Role of interleukin-23 (IL-23) receptor signaling for IL-17 responses in human Lyme disease. Infect Immun. 2011 Nov; 79(11):4681-7. PMID: 21896776.
      Citations: 14     Fields:    Translation:HumansCells
    131. Smeekens SP, van de Veerdonk FL, Joosten LA, Jacobs L, Jansen T, Williams DL, van der Meer JW, Kullberg BJ, Netea MG. The classical CD14?? CD16? monocytes, but not the patrolling CD14? CD16? monocytes, promote Th17 responses to Candida albicans. Eur J Immunol. 2011 Oct; 41(10):2915-24. PMID: 21695694.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    132. Stienstra R, van Diepen JA, Tack CJ, Zaki MH, van de Veerdonk FL, Perera D, Neale GA, Hooiveld GJ, Hijmans A, Vroegrijk I, van den Berg S, Romijn J, Rensen PC, Joosten LA, Netea MG, Kanneganti TD. Inflammasome is a central player in the induction of obesity and insulin resistance. Proc Natl Acad Sci U S A. 2011 Sep 13; 108(37):15324-9. PMID: 21876127.
      Citations: 253     Fields:    Translation:HumansAnimalsCells
    133. van de Veerdonk FL, Joosten LA, Shaw PJ, Smeekens SP, Malireddi RK, van der Meer JW, Kullberg BJ, Netea MG, Kanneganti TD. The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis. Eur J Immunol. 2011 Aug; 41(8):2260-8. PMID: 21681738.
      Citations: 66     Fields:    Translation:AnimalsCells
    134. van de Veerdonk FL, Plantinga TS, Hoischen A, Smeekens SP, Joosten LA, Gilissen C, Arts P, Rosentul DC, Carmichael AJ, Smits-van der Graaf CA, Kullberg BJ, van der Meer JW, Lilic D, Veltman JA, Netea MG. STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis. N Engl J Med. 2011 Jul 07; 365(1):54-61. PMID: 21714643.
      Citations: 239     Fields:    Translation:HumansCells
    135. van de Veerdonk FL, Lauwerys B, Marijnissen RJ, Timmermans K, Di Padova F, Koenders MI, Gutierrez-Roelens I, Durez P, Netea MG, van der Meer JW, van den Berg WB, Joosten LA. The anti-CD20 antibody rituximab reduces the Th17 cell response. Arthritis Rheum. 2011 Jun; 63(6):1507-16. PMID: 21400475.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    136. Cheng SC, van de Veerdonk FL, Lenardon M, Stoffels M, Plantinga T, Smeekens S, Rizzetto L, Mukaremera L, Preechasuth K, Cavalieri D, Kanneganti TD, van der Meer JW, Kullberg BJ, Joosten LA, Gow NA, Netea MG. The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans. J Leukoc Biol. 2011 Aug; 90(2):357-66. PMID: 21531876.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    137. Netea MG, van de Veerdonk FL, van Deuren M, van der Meer JW. Defects of pattern recognition: primary immunodeficiencies of the innate immune system. Curr Opin Pharmacol. 2011 Aug; 11(4):412-22. PMID: 21498117.
      Citations: 3     Fields:    Translation:Humans
    138. Crisan TO, Plantinga TS, van de Veerdonk FL, Farcas MF, Stoffels M, Kullberg BJ, van der Meer JW, Joosten LA, Netea MG. Inflammasome-independent modulation of cytokine response by autophagy in human cells. PLoS One. 2011 Apr 07; 6(4):e18666. PMID: 21490934.
      Citations: 78     Fields:    Translation:HumansCells
    139. Plantinga TS, Crisan TO, Oosting M, van de Veerdonk FL, de Jong DJ, Philpott DJ, van der Meer JW, Girardin SE, Joosten LA, Netea MG. Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2. Gut. 2011 Sep; 60(9):1229-35. PMID: 21406388.
      Citations: 84     Fields:    Translation:HumansCells
    140. van de Veerdonk FL, Netea MG, Dinarello CA, Joosten LA. Inflammasome activation and IL-1ß and IL-18 processing during infection. Trends Immunol. 2011 Mar; 32(3):110-6. PMID: 21333600.
      Citations: 237     Fields:    Translation:HumansAnimalsCells
    141. Giamarellos-Bourboulis EJ, van de Veerdonk FL, Mouktaroudi M, Raftogiannis M, Antonopoulou A, Joosten LA, Pickkers P, Savva A, Georgitsi M, van der Meer JW, Netea MG. Inhibition of caspase-1 activation in Gram-negative sepsis and experimental endotoxemia. Crit Care. 2011; 15(1):R27. PMID: 21244670.
      Citations: 22     Fields:    Translation:HumansCells
    142. Oosting M, van de Veerdonk FL, Kanneganti TD, Sturm P, Verschueren I, Berende A, van der Meer JW, Kullberg BJ, Netea MG, Joosten LA. Borrelia species induce inflammasome activation and IL-17 production through a caspase-1-dependent mechanism. Eur J Immunol. 2011 Jan; 41(1):172-81. PMID: 21182088.
      Citations: 22     Fields:    Translation:AnimalsCells
    143. van der Meer JW, van de Veerdonk FL, Joosten LA, Kullberg BJ, Netea MG. Severe Candida spp. infections: new insights into natural immunity. Int J Antimicrob Agents. 2010 Dec; 36 Suppl 2:S58-62. PMID: 21129931.
      Citations: 16     Fields:    Translation:HumansAnimals
    144. Smeekens SP, van de Veerdonk FL, van der Meer JW, Kullberg BJ, Joosten LA, Netea MG. The Candida Th17 response is dependent on mannan- and beta-glucan-induced prostaglandin E2. Int Immunol. 2010 Nov; 22(11):889-95. PMID: 21059767.
      Citations: 34     Fields:    Translation:AnimalsCells
    145. van de Veerdonk FL, Netea MG, Joosten LA, van der Meer JW, Kullberg BJ. Novel strategies for the prevention and treatment of Candida infections: the potential of immunotherapy. FEMS Microbiol Rev. 2010 Nov; 34(6):1063-75. PMID: 20528948.
      Citations: 14     Fields:    Translation:HumansAnimals
    146. Joosten LA, Netea MG, Mylona E, Koenders MI, Malireddi RK, Oosting M, Stienstra R, van de Veerdonk FL, Stalenhoef AF, Giamarellos-Bourboulis EJ, Kanneganti TD, van der Meer JW. Engagement of fatty acids with Toll-like receptor 2 drives interleukin-1ß production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis. Arthritis Rheum. 2010 Nov; 62(11):3237-48. PMID: 20662061.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    147. Joosten LA, Van De Veerdonk FL, Vonk AG, Boerman OC, Keuter M, Fantuzzi G, Verschueren I, Van Der Poll T, Dinarello CA, Kullberg BJ, Van Der Meer JW, Netea MG. Differential susceptibility to lethal endotoxaemia in mice deficient in IL-1a, IL-1ß or IL-1 receptor type I. APMIS. 2010 Dec; 118(12):1000-7. PMID: 21091783.
      Citations: 11     Fields:    Translation:AnimalsCells
    148. van de Veerdonk FL, Kullberg BJ, Netea MG. Pathogenesis of invasive candidiasis. Curr Opin Crit Care. 2010 Oct; 16(5):453-9. PMID: 20711079.
      Citations: 29     Fields:    Translation:HumansAnimals
    149. van de Veerdonk FL, Netea MG. T-cell Subsets and Antifungal Host Defenses. Curr Fungal Infect Rep. 2010 Dec; 4(4):238-243. PMID: 20976286.
      Citations: 25     
    150. van de Veerdonk FL, Netea MG. Diversity: a hallmark of monocyte society. Immunity. 2010 Sep 24; 33(3):289-91. PMID: 20870168.
      Citations: 19     Fields:    
    151. van de Veerdonk FL, Teirlinck AC, Kleinnijenhuis J, Kullberg BJ, van Crevel R, van der Meer JW, Joosten LA, Netea MG. Mycobacterium tuberculosis induces IL-17A responses through TLR4 and dectin-1 and is critically dependent on endogenous IL-1. J Leukoc Biol. 2010 Aug; 88(2):227-32. PMID: 20299682.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    152. Ippagunta SK, Brand DD, Luo J, Boyd KL, Calabrese C, Stienstra R, Van de Veerdonk FL, Netea MG, Joosten LA, Lamkanfi M, Kanneganti TD. Inflammasome-independent role of apoptosis-associated speck-like protein containing a CARD (ASC) in T cell priming is critical for collagen-induced arthritis. J Biol Chem. 2010 Apr 16; 285(16):12454-62. PMID: 20177071.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    153. van de Veerdonk FL, Smeekens SP, Joosten LA, Kullberg BJ, Dinarello CA, van der Meer JW, Netea MG. Reactive oxygen species-independent activation of the IL-1beta inflammasome in cells from patients with chronic granulomatous disease. Proc Natl Acad Sci U S A. 2010 Feb 16; 107(7):3030-3. PMID: 20133696.
      Citations: 107     Fields:    Translation:HumansCells
    154. van de Veerdonk FL, Gresnigt MS, Kullberg BJ, van der Meer JW, Joosten LA, Netea MG. Th17 responses and host defense against microorganisms: an overview. BMB Rep. 2009 Dec 31; 42(12):776-87. PMID: 20044948.
      Citations: 38     Fields:    Translation:AnimalsCells
    155. Matera G, Muto V, Vinci M, Zicca E, Abdollahi-Roodsaz S, van de Veerdonk FL, Kullberg BJ, Liberto MC, van der Meer JW, Focà A, Netea MG, Joosten LA. Receptor recognition of and immune intracellular pathways for Veillonella parvula lipopolysaccharide. Clin Vaccine Immunol. 2009 Dec; 16(12):1804-9. PMID: 19828771.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    156. Kleinnijenhuis J, Joosten LA, van de Veerdonk FL, Savage N, van Crevel R, Kullberg BJ, van der Ven A, Ottenhoff TH, Dinarello CA, van der Meer JW, Netea MG. Transcriptional and inflammasome-mediated pathways for the induction of IL-1beta production by Mycobacterium tuberculosis. Eur J Immunol. 2009 Jul; 39(7):1914-22. PMID: 19544485.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    157. van de Veerdonk FL, Marijnissen RJ, Kullberg BJ, Koenen HJ, Cheng SC, Joosten I, van den Berg WB, Williams DL, van der Meer JW, Joosten LA, Netea MG. The macrophage mannose receptor induces IL-17 in response to Candida albicans. Cell Host Microbe. 2009 Apr 23; 5(4):329-40. PMID: 19380112.
      Citations: 144     Translation:HumansAnimalsCells
    158. van de Veerdonk FL, Joosten LA, Devesa I, Mora-Montes HM, Kanneganti TD, Dinarello CA, van der Meer JW, Gow NA, Kullberg BJ, Netea MG. Bypassing pathogen-induced inflammasome activation for the regulation of interleukin-1beta production by the fungal pathogen Candida albicans. J Infect Dis. 2009 Apr 01; 199(7):1087-96. PMID: 19222370.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    159. Netea MG, Nold-Petry CA, Nold MF, Joosten LA, Opitz B, van der Meer JH, van de Veerdonk FL, Ferwerda G, Heinhuis B, Devesa I, Funk CJ, Mason RJ, Kullberg BJ, Rubartelli A, van der Meer JW, Dinarello CA. Differential requirement for the activation of the inflammasome for processing and release of IL-1beta in monocytes and macrophages. Blood. 2009 Mar 05; 113(10):2324-35. PMID: 19104081.
      Citations: 314     Fields:    Translation:HumansAnimalsCells
    160. Netea MG, van de Veerdonk FL, Kullberg BJ, Van der Meer JW, Joosten LA. The role of NLRs and TLRs in the activation of the inflammasome. Expert Opin Biol Ther. 2008 Dec; 8(12):1867-72. PMID: 18990074.
      Citations: 23     Fields:    Translation:HumansAnimals
    161. van de Veerdonk FL, Kullberg BJ, van der Meer JW, Gow NA, Netea MG. Host-microbe interactions: innate pattern recognition of fungal pathogens. Curr Opin Microbiol. 2008 Aug; 11(4):305-12. PMID: 18602019.
      Citations: 60     Fields:    Translation:HumansAnimals
    van de Veerdonk's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (294)
    Explore
    _
    Co-Authors (459)
    Explore
    _
    Similar People (60)
    Explore
    _