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Alessandro D Santin
Institution
Yale University School of Medicine
Address
New Haven
Connecticut
United States
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Publication Timeline
COVID-19 publications
All Publications
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To see the data from both graphs as text,
click here
.
Year
Publications
1995
1
1996
7
1997
4
1998
9
1999
5
2000
8
2001
5
2002
6
2003
7
2004
7
2005
11
2006
5
2007
11
2008
6
2009
7
2010
11
2011
19
2012
7
2013
14
2014
14
2015
16
2016
16
2017
7
2018
11
2019
3
2021
2
These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.
To return to the graphs,
click here
.
Publication Field Summary
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text,
click here
.
Publication List
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Santin AD
,
Scheim DE
,
McCullough PA
,
Yagisawa M
,
Borody TJ
. Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19. New Microbes New Infect. 2021 Sep; 43:100924.
PMID:
34466270
.
Citations:
Levi G
,
Rocchetti C
,
Magri R
,
Uccelli S
,
Bottone D
,
Quadri F
,
Novali M
,
Santin AD
,
Bezzi M
. Hyperimmune plasma infusion in an immunocompromised Covid-19 patient previously treated for follicular lymphoma. Monaldi Arch Chest Dis. 2021 Jun 10; 91(4).
PMID:
34121379
.
Citations:
Fields:
Pul
Pulmonary Medicine
Bardia A
,
Mayer IA
, Vahdat LT,
Tolaney SM
,
Isakoff SJ
, Diamond JR,
O'Shaughnessy J
, Moroose RL,
Santin AD
, Abramson VG, Shah NC,
Rugo HS
, Goldenberg DM, Sweidan AM, Iannone R, Washkowitz S, Sharkey RM, Wegener WA,
Kalinsky K
. Sacituzumab Govitecan-hziy in Refractory Metastatic Triple-Negative Breast Cancer. N Engl J Med. 2019 02 21; 380(8):741-751.
PMID:
30786188
.
Citations:
139
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Boettcher AN
, Kiupel M, Adur MK, Cocco E,
Santin AD
, Bellone S, Charley SE, Blanco-Fernandez B, Risinger JI, Ross JW, Tuggle CK, Shapiro EM. Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient (SCID) Pigs. Front Oncol. 2019; 9:9.
PMID:
30723704
.
Citations:
4
Feinberg J, Albright B,
Black J
, Lu L, Passarelli R, Gysler S, Whicker M, Altwerger G, Menderes G,
Hui P
,
Santin AD
, Azodi M, Silasi DA, Ratner ES, Litkouhi B, Schwartz PE. Ten-Year Comparison Study of Type 1 and 2 Endometrial Cancers: Risk Factors and Outcomes. Gynecol Obstet Invest. 2019; 84(3):290-297.
PMID:
30602164
.
Citations:
5
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Lopez S
, Zeybek B,
Santin AD
. Targeting Her2/neu in uterine serous carcinoma: A paradigm shift in management. Oncotarget. 2018 Nov 30; 9(94):36652-36653.
PMID:
30613348
.
Fields:
Neo
Neoplasms
Zeybek B,
Lopez S
,
Santin AD
. BET inhibitors: Betting on improved outcomes in uterine serous carcinoma. Oncotarget. 2018 Oct 26; 9(84):35470-35471.
PMID:
30464799
.
Citations:
2
Fields:
Neo
Neoplasms
Menderes G,
Lopez S
, Han C, Altwerger G, Gysler S, Varughese J, Schwartz PE,
Santin AD
. Mechanisms of resistance to HER2-targeted therapies in HER2-amplified uterine serous carcinoma, and strategies to overcome it. Discov Med. 2018 08; 26(141):39-50.
PMID:
30265854
.
Citations:
7
Fields:
Med
Medicine (General)
Translation:
Humans
Han C, Altwerger G, Menderes G, Haines K, Feinberg J,
Lopez S
, Manzano A, Varughese J,
Santin AD
. Novel targeted therapies in ovarian and uterine carcinosarcomas. Discov Med. 2018 Jun; 25(140):309-319.
PMID:
30021104
.
Citations:
6
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Han C, Bellone S, Zammataro L, Schwartz PE,
Santin AD
. Binimetinib (MEK162) in recurrent low-grade serous ovarian cancer resistant to chemotherapy and hormonal treatment. Gynecol Oncol Rep. 2018 Aug; 25:41-44.
PMID:
29946554
.
Citations:
5
Han C, Bellone S, Schwartz PE, Govindan SV, Sharkey RM, Goldenberg DM,
Santin AD
. Sacituzumab Govitecan (IMMU-132) in treatment-resistant uterine serous carcinoma: A case report. Gynecol Oncol Rep. 2018 Aug; 25:37-40.
PMID:
29977989
.
Citations:
5
Fader AN
, Roque DM, Siegel E, Buza N,
Hui P
,
Abdelghany O
, Chambers SK,
Secord AA
, Havrilesky L,
O'Malley DM
, Backes F, Nevadunsky N, Edraki B, Pikaart D, Lowery W, ElSahwi KS, Celano P, Bellone S, Azodi M, Litkouhi B,
Ratner E
, Silasi DA, Schwartz PE,
Santin AD
. Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That Overexpress Human Epidermal Growth Factor Receptor 2/neu. J Clin Oncol. 2018 07 10; 36(20):2044-2051.
PMID:
29584549
.
Citations:
78
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Han C, Bellone S, Siegel ER, Altwerger G, Menderes G, Bonazzoli E, Egawa-Takata T, Pettinella F,
Bianchi A
, Riccio F, Zammataro L, Yadav G, Marto JA, Penet MF, Levine DA, Drapkin R, Patel A, Litkouhi B,
Ratner E
, Silasi DA, Huang GS, Azodi M, Schwartz PE,
Santin AD
. A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma. Gynecol Oncol. 2018 06; 149(3):585-591.
PMID:
29572027
.
Citations:
16
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Hui P
, Gysler SM, Uduman M, Togun TA, Prado DE, Brambs CE, Nallur S, Schwartz PE, Rutherford TJ,
Santin AD
, Weidhaas JB, Ratner ES. MicroRNA signatures discriminate between uterine and ovarian serous carcinomas. Hum Pathol. 2018 06; 76:133-140.
PMID:
29518404
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Cells
Altwerger G, Bonazzoli E, Bellone S, Egawa-Takata T, Menderes G, Pettinella F,
Bianchi A
, Riccio F, Feinberg J, Zammataro L, Han C, Yadav G, Dugan K, Morneault A, Ponte JF, Buza N,
Hui P
, Wong S, Litkouhi B,
Ratner E
, Silasi DA, Huang GS, Azodi M, Schwartz PE,
Santin AD
. In Vitro and In Vivo Activity of IMGN853, an Antibody-Drug Conjugate Targeting Folate Receptor Alpha Linked to DM4, in Biologically Aggressive Endometrial Cancers. Mol Cancer Ther. 2018 05; 17(5):1003-1011.
PMID:
29440294
.
Citations:
8
Translation:
Humans
Animals
Cells
Albright BB, Black JD, Passarelli R, Gysler S, Whicker M, Altwerger G, Menderes G, Buza N,
Hui P
,
Santin AD
, Azodi M, Silasi DA, Ratner ES, Litkouhi B, Schwartz PE. Associated characteristics and impact on recurrence and survival of free-floating tumor fragments in the lumen of fallopian tubes in Type I and Type II endometrial cancer. Gynecol Oncol Rep. 2018 Feb; 23:28-33.
PMID:
29387776
.
Citations:
1
Menderes G, Bonazzoli E, Bellone S, Altwerger G, Black JD, Dugan K, Pettinella F, Masserdotti A, Riccio F,
Bianchi A
, Zammataro L, de Haydu C, Buza N,
Hui P
, Wong S, Huang GS, Litkouhi B,
Ratner E
, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. Superior in vitro and in vivo activity of trastuzumab-emtansine (T-DM1) in comparison to trastuzumab, pertuzumab and their combination in epithelial ovarian carcinoma with high HER2/neu expression. Gynecol Oncol. 2017 10; 147(1):145-152.
PMID:
28705408
.
Citations:
7
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Menderes G, Bonazzoli E, Bellone S,
Black J
, Predolini F, Pettinella F, Masserdotti A, Zammataro L, Altwerger G, Buza N,
Hui P
, Wong S, Litkouhi B,
Ratner E
, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine and Ovarian Carcinosarcoma with HER2/Neu Expression. Clin Cancer Res. 2017 Oct 01; 23(19):5836-5845.
PMID:
28679774
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Huang GS,
Santin AD
. Genetic landscape of clear cell endometrial cancer and the era of precision medicine. Cancer. 2017 09 01; 123(17):3216-3218.
PMID:
28485840
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Tassi RA, Todeschini P, Siegel ER,
Calza S
, Cappella P, Ardighieri L, Cadei M,
Bugatti M
, Romani C, Bandiera E, Zanotti L, Tassone L, Guarino D,
Santonocito C
,
Capoluongo ED
, Beltrame L, Erba E, Marchini S, D'Incalci M, Donzelli C,
Santin AD
,
Pecorelli S
,
Sartori E
, Bignotti E, Odicino F, Ravaggi A. FOXM1 expression is significantly associated with chemotherapy resistance and adverse prognosis in non-serous epithelial ovarian cancer patients. J Exp Clin Cancer Res. 2017 05 08; 36(1):63.
PMID:
28482906
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Menderes G, Bonazzoli E, Bellone S,
Black J
, Altwerger G, Masserdotti A, Pettinella F, Zammataro L, Buza N,
Hui P
, Wong S, Litkouhi B,
Ratner E
, Silasi DA, Huang GS, Azodi M, Schwartz PE,
Santin AD
. SYD985, a novel duocarmycin-based HER2-targeting antibody-drug conjugate, shows promising antitumor activity in epithelial ovarian carcinoma with HER2/Neu expression. Gynecol Oncol. 2017 07; 146(1):179-186.
PMID:
28473206
.
Citations:
13
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Menderes G, Bonazzoli E, Bellone S, Black JD,
Lopez S
, Pettinella F, Masserdotti A, Zammataro L, Litkouhi B,
Ratner E
, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. Efficacy of neratinib in the treatment of HER2/neu-amplified epithelial ovarian carcinoma in vitro and in vivo. Med Oncol. 2017 May; 34(5):91.
PMID:
28397106
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Carvajal-Hausdorf DE, Schalper KA, Bai Y,
Black J
,
Santin AD
, Rimm DL. Objective, domain-specific HER2 measurement in uterine and ovarian serous carcinomas and its clinical significance. Gynecol Oncol. 2017 04; 145(1):154-158.
PMID:
28196634
.
Citations:
5
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Buza N, Schwartz PE. Regression of metastatic, radiation/chemotherapy-resistant uterine serous carcinoma overexpressing HER2/neu with trastuzumab emtansine (TDM-1). Gynecol Oncol Rep. 2017 Feb; 19:10-12.
PMID:
28018954
.
Citations:
4
Roque DM,
Santin AD
. Uterine cancer, mutational phenotype, and the era of immune checkpoint blockade. Expert Rev Clin Immunol. 2017 03; 13(3):175-180.
PMID:
27905822
.
Citations:
1
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cocco E, Deng Y, Shapiro EM, Bortolomai I,
Lopez S
,
Lin K
, Bellone S, Cui J, Menderes G, Black JD, Schwab CL, Bonazzoli E, Yang F, Predolini F, Zammataro L, Altwerger G, de Haydu C, Clark M, Alvarenga J,
Ratner E
, Azodi M, Silasi DA, Schwartz PE, Litkouhi B, Saltzman WM,
Santin AD
. Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells. Mol Cancer Ther. 2017 02; 16(2):323-333.
PMID:
27956521
.
Citations:
11
Translation:
Humans
Animals
Cells
Bellone S, Bignotti E, Lonardi S,
Ferrari F
, Centritto F, Masserdotti A, Pettinella F,
Black J
, Menderes G, Altwerger G,
Hui P
,
Lopez S
, de Haydu C, Bonazzoli E, Predolini F, Zammataro L, Cocco E, Ferrari F, Ravaggi A, Romani C,
Facchetti F
,
Sartori E
, Odicino FE, Silasi DA, Litkouhi B,
Ratner E
, Azodi M, Schwartz PE,
Santin AD
. Polymerase e (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro. Gynecol Oncol. 2017 Jan; 144(1):146-152.
PMID:
27894751
.
Citations:
18
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Yin M
, Li X, Tan S, Zhou HJ,
Ji W
, Bellone S, Xu X, Zhang H,
Santin AD
, Lou G, Min W. Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer. J Clin Invest. 2016 11 01; 126(11):4157-4173.
PMID:
27721235
.
Citations:
104
Fields:
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Zhao S, Bellone S,
Lopez S
, Thakral D, Schwab C, English DP,
Black J
, Cocco E,
Choi J
, Zammataro L, Predolini F, Bonazzoli E, Bi M, Buza N,
Hui P
, Wong S, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Odicino F,
Pecorelli S
, Donzelli C, Ardighieri L,
Facchetti F
, Falchetti M, Silasi DA,
Ratner E
, Azodi M, Schwartz PE,
Mane S
,
Angioli R
, Terranova C, Quick CM, Edraki B, Bilgüvar K, Lee M, Choi M, Stiegler AL, Boggon TJ, Schlessinger J,
Lifton RP
,
Santin AD
. Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):12238-12243.
PMID:
27791010
.
Citations:
69
Fields:
Sci
Science
Translation:
Humans
Deng Y, Yang F, Cocco E,
Song E
, Zhang J, Cui J, Mohideen M, Bellone S,
Santin AD
, Saltzman WM. Improved i.p. drug delivery with bioadhesive nanoparticles. Proc Natl Acad Sci U S A. 2016 10 11; 113(41):11453-11458.
PMID:
27663731
.
Citations:
19
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Hoque SM, Huang Y, Cocco E, Maritim S,
Santin AD
, Shapiro EM, Coman D, Hyder F. Improved specific loss power on cancer cells by hyperthermia and MRI contrast of hydrophilic Fex Co1-x Fe2 O4 nanoensembles. Contrast Media Mol Imaging. 2016 11; 11(6):514-526.
PMID:
27659164
.
Citations:
4
Fields:
Dia
Diagnostic Imaging
Translation:
Humans
Animals
Cells
Santin AD
, Bellone S, Buza N,
Choi J
, Schwartz PE, Schlessinger J,
Lifton RP
. Regression of Chemotherapy-Resistant Polymerase e (POLE) Ultra-Mutated and MSH6 Hyper-Mutated Endometrial Tumors with Nivolumab. Clin Cancer Res. 2016 Dec 01; 22(23):5682-5687.
PMID:
27486176
.
Citations:
48
Fields:
Neo
Neoplasms
Translation:
Humans
Cocco E,
Lopez S
,
Black J
, Bellone S, Bonazzoli E, Predolini F,
Ferrari F
, Schwab CL, Menderes G, Zammataro L, Buza N,
Hui P
, Wong S, Zhao S, Bai Y, Rimm DL,
Ratner E
, Litkouhi B, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo. Br J Cancer. 2016 07 26; 115(3):303-11.
PMID:
27351214
.
Citations:
8
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Black J
, Menderes G, Bellone S, Schwab CL, Bonazzoli E,
Ferrari F
, Predolini F, De Haydu C, Cocco E, Buza N,
Hui P
, Wong S,
Lopez S
,
Ratner E
, Silasi DA, Azodi M, Litkouhi B, Schwartz PE, Goedings P, Beusker PH, van der Lee MM, Timmers CM, Dokter WH,
Santin AD
. SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression. Mol Cancer Ther. 2016 08; 15(8):1900-9.
PMID:
27256376
.
Citations:
15
Translation:
Humans
Animals
Cells
English DP, Menderes G,
Black J
, Schwab CL,
Santin AD
. Molecular diagnosis and molecular profiling to detect treatment-resistant ovarian cancer. Expert Rev Mol Diagn. 2016 07; 16(7):769-82.
PMID:
27169329
.
Citations:
4
Fields:
Mol
Molecular Biology
Translation:
Humans
Roque DM,
Santin AD
. Oncofertility in gynecologic oncology: an oxymoron? Future Oncol. 2016 Jul; 12(14):1683-6.
PMID:
27173792
.
Fields:
Neo
Neoplasms
Translation:
Humans
Menderes G,
Hicks C
, Black JD, Schwab CL,
Santin AD
. Immune checkpoint inhibitors in gynecologic cancers with lessons learned from non-gynecologic cancers. Expert Opin Biol Ther. 2016 08; 16(8):989-1004.
PMID:
27070175
.
Citations:
3
Fields:
Bio
Biology
The
Therapeutics
Translation:
Humans
Menderes G, Clark M,
Santin AD
. Novel targeted therapies in uterine serous carcinoma, an aggressive variant of endometrial cancer. Discov Med. 2016 04; 21(116):293-303.
PMID:
27232515
.
Citations:
5
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Menderes G, Schwab CL,
Black J
,
Santin AD
. The Role of the Immune System in Ovarian Cancer and Implications on Therapy. Expert Rev Clin Immunol. 2016 Jun; 12(6):681-95.
PMID:
26821930
.
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
de Haydu C, Black JD, Schwab CL, English DP,
Santin AD
. An update on the current pharmacotherapy for endometrial cancer. Expert Opin Pharmacother. 2016; 17(4):489-99.
PMID:
26629895
.
Citations:
7
Fields:
Pha
Pharmacology
Translation:
Humans
Menderes G,
Black J
, Schwab CL,
Santin AD
. Immunotherapy and targeted therapy for cervical cancer: an update. Expert Rev Anticancer Ther. 2016; 16(1):83-98.
PMID:
26568261
.
Citations:
32
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Black JD,
Lopez S
, Cocco E, Bellone S, Altwerger G, Schwab CL, English DP, Bonazzoli E, Predolini F,
Ferrari F
,
Ratner E
, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas. Br J Cancer. 2015 Dec 01; 113(11):1641.
PMID:
26625219
.
Citations:
8
Fields:
Neo
Neoplasms
Ferrari F
, Bellone S,
Black J
, Schwab CL,
Lopez S
, Cocco E, Bonazzoli E, Predolini F, Menderes G, Litkouhi B,
Ratner E
, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE®), is highly active against primary uterine and ovarian carcinosarcoma cell lines in vitro. J Exp Clin Cancer Res. 2015 Oct 17; 34:123.
PMID:
26474755
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Lopez S
, Cocco E,
Black J
, Bellone S, Bonazzoli E, Predolini F,
Ferrari F
, Schwab CL, English DP,
Ratner E
, Silasi DA, Azodi M, Schwartz PE, Terranova C,
Angioli R
,
Santin AD
. Dual HER2/PIK3CA Targeting Overcomes Single-Agent Acquired Resistance in HER2-Amplified Uterine Serous Carcinoma Cell Lines In Vitro and In Vivo. Mol Cancer Ther. 2015 Nov; 14(11):2519-26.
PMID:
26333383
.
Citations:
15
Translation:
Humans
Animals
Cells
Black JD,
Lopez S
, Cocco E, Bellone S, Altwerger G, Schwab CL, English DP, Bonazzoli E, Predolini F,
Ferrari F
,
Ratner E
, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas. Br J Cancer. 2015 Sep 29; 113(7):1020-6.
PMID:
26325104
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cocco E, Shapiro EM, Gasparrini S,
Lopez S
, Schwab CL, Bellone S, Bortolomai I, Sumi NJ, Bonazzoli E, Nicoletti R, Deng Y, Saltzman WM,
Zeiss CJ
, Centritto F, Black JD, Silasi DA,
Ratner E
, Azodi M, Rutherford TJ, Schwartz PE,
Pecorelli S
,
Santin AD
. Clostridium perfringens enterotoxin C-terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy-resistant ovarian cancer. Int J Cancer. 2015 Dec 01; 137(11):2618-29.
PMID:
26060989
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Santin AD
, Roque DM. Reply: To PMID 25577672. Am J Obstet Gynecol. 2015 Dec; 213(6):881.
PMID:
26292047
.
Citations:
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Bellone S,
Black J
, English DP, Schwab CL,
Lopez S
, Cocco E, Bonazzoli E, Predolini F,
Ferrari F
,
Ratner E
, Silasi DA, Azodi M, Schwartz PE,
Santin AD
. Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE), is highly active against primary uterine serous papillary carcinoma cell lines in vitro. Am J Obstet Gynecol. 2016 Jan; 214(1):99.e1-8.
PMID:
26272866
.
Citations:
6
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Schwab CL, English DP,
Black J
, Bellone S,
Lopez S
, Cocco E, Bonazzoli E, Bussi B, Predolini F,
Ferrari F
,
Ratner E
, Silasi DA, Azodi M, Rutherford T, Schwartz PE,
Santin AD
. Neratinib shows efficacy in the treatment of HER2 amplified carcinosarcoma in vitro and in vivo. Gynecol Oncol. 2015 Oct; 139(1):112-7.
PMID:
26260909
.
Citations:
9
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Black JD, Altwerger GH,
Ratner E
, Lu L, Silasi DA, Azodi M,
Santin AD
, Schwartz PE, Rutherford TJ. Management of Borderline Ovarian Tumors Based on Patient and Tumor Characteristics. Gynecol Obstet Invest. 2015 Jun 06.
PMID:
26067608
.
Citations:
1
Fields:
Gyn
Gynecology
Obs
Obstetrics
Bellone S, Centritto F,
Black J
, Schwab C, English D, Cocco E,
Lopez S
, Bonazzoli E, Predolini F,
Ferrari F
, Silasi DA,
Ratner E
, Azodi M, Schwartz PE,
Santin AD
. Polymerase e (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients. Gynecol Oncol. 2015 Jul; 138(1):11-7.
PMID:
25931171
.
Citations:
27
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Roque DM, Ratner ES, Silasi DA, Azodi M, Rutherford TJ, Schwartz PE, Nelson WK,
Santin AD
. Weekly ixabepilone with or without biweekly bevacizumab in the treatment of recurrent or persistent uterine and ovarian/primary peritoneal/fallopian tube cancers: A retrospective review. Gynecol Oncol. 2015 Jun; 137(3):392-400.
PMID:
25792179
.
Citations:
6
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Zhu L,
Lopez S
, Bellone S,
Black J
, Cocco E, Zigras T, Predolini F, Bonazzoli E, Bussi B, Stuhmer Z, Schwab CL, English DP,
Ratner E
, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Santin AD
. Dacomitinib (PF-00299804), a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor, demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro. Tumour Biol. 2015 Jul; 36(7):5505-13.
PMID:
25669172
.
Citations:
2
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Miller DT, Roque DM,
Santin AD
. Use of Monsel solution to treat obstetrical hemorrhage: a review and comparison to other topical hemostatic agents. Am J Obstet Gynecol. 2015 Jun; 212(6):725-35.
PMID:
25577672
.
Citations:
1
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Schwab CL,
Santin AD
. Targeted therapy in the treatment of uterine serous carcinoma. Pharmacogenomics. 2015 Jan; 16(2):97-9.
PMID:
25616096
.
Citations:
3
Fields:
Gen
Genetics
Pha
Pharmacology
Translation:
Humans
Romani C,
Calza S
, Todeschini P, Tassi RA, Zanotti L, Bandiera E,
Sartori E
,
Pecorelli S
, Ravaggi A,
Santin AD
, Bignotti E. Identification of optimal reference genes for gene expression normalization in a wide cohort of endometrioid endometrial carcinoma tissues. PLoS One. 2014; 9(12):e113781.
PMID:
25473950
.
Citations:
9
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Nicoletti R,
Lopez S
, Bellone S, Cocco E, Schwab CL, Black JD, Centritto F, Zhu L, Bonazzoli E, Buza N,
Hui P
, Mezzanzanica D, Canevari S, Schwartz PE, Rutherford TJ,
Santin AD
. T-DM1, a novel antibody-drug conjugate, is highly effective against uterine and ovarian carcinosarcomas overexpressing HER2. Clin Exp Metastasis. 2015 Jan; 32(1):29-38.
PMID:
25398397
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Animals
Cells
Schwab CL, Bellone S, English DP, Roque DM, Lopez S, Cocco E, Nicoletti R, Bortolomai I, Bonazzoli E, Ratner E, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Santin AD
. Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo. Br J Cancer. 2014 Oct 28; 111(9):1750-6.
PMID:
25268372
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
English DP, Bellone S, Schwab CL, Roque DM,
Lopez S
, Bortolomai I, Cocco E, Bonazzoli E, Chatterjee S,
Ratner E
, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Santin AD
. Solitomab, an epithelial cell adhesion molecule/CD3 bispecific antibody (BiTE), is highly active against primary chemotherapy-resistant ovarian cancer cell lines in vitro and fresh tumor cells ex vivo. Cancer. 2015 Feb 01; 121(3):403-12.
PMID:
25251053
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Lopez S
, Schwab CL, Cocco E, Bellone S, Bonazzoli E, English DP, Schwartz PE, Rutherford T,
Angioli R
,
Santin AD
. Taselisib, a selective inhibitor of PIK3CA, is highly effective on PIK3CA-mutated and HER2/neu amplified uterine serous carcinoma in vitro and in vivo. Gynecol Oncol. 2014 Nov; 135(2):312-7.
PMID:
25172762
.
Citations:
16
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Schwab CL, English DP, Roque DM, Bellone S,
Lopez S
, Cocco E, Nicoletti R, Rutherford TJ, Schwartz PE,
Santin AD
. Neratinib shows efficacy in the treatment of HER2/neu amplified uterine serous carcinoma in vitro and in vivo. Gynecol Oncol. 2014 Oct; 135(1):142-8.
PMID:
25124161
.
Citations:
12
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Animals
Cells
Yan L, Zhou J, Gao Y, Ghazal S, Lu L, Bellone S, Yang Y, Liu N, Zhao X,
Santin AD
, Taylor H, Huang Y. Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation. Oncogene. 2015 Jun 04; 34(23):3076-84.
PMID:
25088204
.
Citations:
99
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Menderes G, Azodi M, Clark L, Xu X, Lu L,
Ratner E
, Schwartz PE, Rutherford TJ,
Santin AD
, Silasi DA. Impact of body mass index on surgical outcomes and analysis of disease recurrence for patients with endometrial cancer undergoing robotic-assisted staging. Int J Gynecol Cancer. 2014 Jul; 24(6):1118-25.
PMID:
24927247
.
Citations:
2
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
English DP, Bellone S, Schwab CL, Bortolomai I, Bonazzoli E, Cocco E, Buza N,
Hui P
,
Lopez S
,
Ratner E
, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Santin AD
. T-DM1, a novel antibody-drug conjugate, is highly effective against primary HER2 overexpressing uterine serous carcinoma in vitro and in vivo. Cancer Med. 2014 Oct; 3(5):1256-65.
PMID:
24890382
.
Citations:
18
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Schwab CL, English DP, Roque DM,
Santin AD
. Taxanes: their impact on gynecologic malignancy. Anticancer Drugs. 2014 May; 25(5):522-35.
PMID:
24300913
.
Citations:
6
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Buza N, Roque DM,
Santin AD
. HER2/neu in Endometrial Cancer: A Promising Therapeutic Target With Diagnostic Challenges. Arch Pathol Lab Med. 2014 Mar; 138(3):343-50.
PMID:
24576030
.
Citations:
42
Fields:
Pat
Pathology
Translation:
Humans
Acevedo-Gadea C,
Santin AD
, Higgins SA, Urva S,
Ratner E
, Silasi DA, Azodi M, Rutherford T, Schwartz PE, Abu-Khalaf MM. Phase I clinical trial of the mammalian target of rapamycin inhibitor everolimus in combination with oral topotecan for recurrent and advanced endometrial cancer. Int J Gynecol Cancer. 2014 Mar; 24(3):528-33.
PMID:
24557436
.
Citations:
2
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Black JD, English DP, Roque DM,
Santin AD
. Targeted therapy in uterine serous carcinoma: an aggressive variant of endometrial cancer. Womens Health (Lond). 2014 Jan; 10(1):45-57.
PMID:
24328598
.
Citations:
16
Fields:
Wom
Women's Health
Translation:
Humans
Schwab CL, English DP, Roque DM, Pasternak M,
Santin AD
. Past, present and future targets for immunotherapy in ovarian cancer. Immunotherapy. 2014; 6(12):1279-93.
PMID:
25524384
.
Citations:
18
Fields:
All
Allergy and Immunology
The
Therapeutics
Translation:
Humans
Animals
Roque DM, Buza N, Glasgow M, Bellone S, Bortolomai I, Gasparrini S, Cocco E,
Ratner E
, Silasi DA, Azodi M, Rutherford TJ, Schwartz PE,
Santin AD
. Class III ß-tubulin overexpression within the tumor microenvironment is a prognostic biomarker for poor overall survival in ovarian cancer patients treated with neoadjuvant carboplatin/paclitaxel. Clin Exp Metastasis. 2014 Jan; 31(1):101-10.
PMID:
24005572
.
Citations:
22
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
English DP, Roque DM, Carrara L,
Lopez S
, Bellone S, Cocco E, Bortolomai I, Schwartz PE, Rutherford T,
Santin AD
. HER2/neu gene amplification determines the sensitivity of uterine serous carcinoma cell lines to AZD8055, a novel dual mTORC1/2 inhibitor. Gynecol Oncol. 2013 Dec; 131(3):753-8.
PMID:
24012800
.
Citations:
12
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
English DP, Bellone S, Cocco E, Bortolomai I,
Pecorelli S
,
Lopez S
, Silasi DA, Schwartz PE, Rutherford T,
Santin AD
. Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2). Am J Obstet Gynecol. 2013 Nov; 209(5):465.e1-9.
PMID:
23891627
.
Citations:
13
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Bignotti E, Tassi RA,
Calza S
, Ravaggi A,
Rossi E
, Donzelli C, Todeschini P, Romani C, Bandiera E, Zanotti L, Carnazza M, Quadraro F, Tognon G,
Sartori E
,
Pecorelli S
, Roque DM,
Santin AD
. Secretoglobin expression in ovarian carcinoma: lipophilin B gene upregulation as an independent marker of better prognosis. J Transl Med. 2013 Jul 02; 11:162.
PMID:
23819652
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Bellone S, Tassi R, Betti M, English D, Cocco E, Gasparrini S, Bortolomai I, Black JD, Todeschini P, Romani C, Ravaggi A, Bignotti E, Bandiera E, Zanotti L, Pecorelli S, Ardighieri L, Falchetti M, Donzelli C, Siegel ER, Azodi M, Silasi DA, Ratner E, Schwartz PE, Rutherford TJ,
Santin AD
. Mammaglobin B (SCGB2A1) is a novel tumour antigen highly differentially expressed in all major histological types of ovarian cancer: implications for ovarian cancer immunotherapy. Br J Cancer. 2013 Jul 23; 109(2):462-71.
PMID:
23807163
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Buza N, English DP,
Santin AD
,
Hui P
. Toward standard HER2 testing of endometrial serous carcinoma: 4-year experience at a large academic center and recommendations for clinical practice. Mod Pathol. 2013 Dec; 26(12):1605-12.
PMID:
23765245
.
Citations:
33
Fields:
Pat
Pathology
Translation:
Humans
English DP,
Santin AD
. Claudins overexpression in ovarian cancer: potential targets for Clostridium Perfringens Enterotoxin (CPE) based diagnosis and therapy. Int J Mol Sci. 2013 May 17; 14(5):10412-37.
PMID:
23685873
.
Citations:
18
Fields:
Bio
Biochemistry
Che
Chemistry
Mol
Molecular Biology
Translation:
Humans
Animals
Roque DM, Bellone S, English DP, Buza N, Cocco E, Gasparrini S, Bortolomai I,
Ratner E
, Silasi DA, Azodi M, Rutherford TJ, Schwartz PE,
Santin AD
. Tubulin-ß-III overexpression by uterine serous carcinomas is a marker for poor overall survival after platinum/taxane chemotherapy and sensitivity to epothilones. Cancer. 2013 Jul 15; 119(14):2582-92.
PMID:
23585021
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Roque DM, Bellone S, Buza N, Romani C, Cocco E, Bignotti E, Ravaggi A, Rutherford TJ, Schwartz PE,
Pecorelli S
,
Santin AD
. Class III ß-tubulin overexpression in ovarian clear cell and serous carcinoma as a maker for poor overall survival after platinum/taxane chemotherapy and sensitivity to patupilone. Am J Obstet Gynecol. 2013 Jul; 209(1):62.e1-9.
PMID:
23583215
.
Citations:
13
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
English DP, Roque DM,
Santin AD
. HER2 expression beyond breast cancer: therapeutic implications for gynecologic malignancies. Mol Diagn Ther. 2013 Apr; 17(2):85-99.
PMID:
23529353
.
Citations:
63
Fields:
Cli
Clinical Laboratory Techniques
Mol
Molecular Biology
Pha
Pharmacology
Translation:
Humans
Animals
Cells
Roque DM,
Santin AD
. Updates in therapy for uterine serous carcinoma. Curr Opin Obstet Gynecol. 2013 Feb; 25(1):29-37.
PMID:
23138439
.
Citations:
5
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Zhao S, Choi M,
Overton JD
, Bellone S, Roque DM, Cocco E, Guzzo F, English DP, Varughese J, Gasparrini S, Bortolomai I, Buza N,
Hui P
, Abu-Khalaf M, Ravaggi A, Bignotti E, Bandiera E, Romani C, Todeschini P, Tassi R, Zanotti L, Carrara L,
Pecorelli S
, Silasi DA,
Ratner E
, Azodi M, Schwartz PE, Rutherford TJ, Stiegler AL,
Mane S
, Boggon TJ, Schlessinger J,
Lifton RP
,
Santin AD
. Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma. Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8):2916-21.
PMID:
23359684
.
Citations:
129
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Fader AN
,
Santin AD
, Gehrig PA. Early stage uterine serous carcinoma: management updates and genomic advances. Gynecol Oncol. 2013 Apr; 129(1):244-50.
PMID:
23321062
.
Citations:
13
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
English DP, Roque DM,
Santin AD
. Class III b-tubulin overexpression in gynecologic tumors: implications for the choice of microtubule targeted agents? Expert Rev Anticancer Ther. 2013 Jan; 13(1):63-74.
PMID:
23259428
.
Citations:
3
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Bignotti E, Zanotti L,
Calza S
, Falchetti M, Lonardi S, Ravaggi A, Romani C, Todeschini P, Bandiera E, Tassi RA,
Facchetti F
,
Sartori E
,
Pecorelli S
, Roque DM,
Santin AD
. Trop-2 protein overexpression is an independent marker for predicting disease recurrence in endometrioid endometrial carcinoma. BMC Clin Pathol. 2012 Nov 14; 12:22.
PMID:
23151048
.
Citations:
15
Lal-Nag M, Battis M,
Santin AD
, Morin PJ. Claudin-6: a novel receptor for CPE-mediated cytotoxicity in ovarian cancer. Oncogenesis. 2012 Nov 12; 1:e33.
PMID:
23552466
.
Citations:
18
Glasgow MA, Yu H, Rutherford TJ, Azodi M, Silasi DA,
Santin AD
, Schwartz PE. Neoadjuvant chemotherapy (NACT) is an effective way of managing elderly women with advanced stage ovarian cancer (FIGO Stage IIIC and IV). J Surg Oncol. 2013 Feb; 107(2):195-200.
PMID:
22648987
.
Citations:
16
Fields:
Gen
General Surgery
Neo
Neoplasms
Translation:
Humans
Guzzo F, Bellone S, Buza N,
Hui P
, Carrara L, Varughese J, Cocco E,
Betti M
, Todeschini P, Gasparrini S, Schwartz PE, Rutherford TJ,
Angioli R
,
Pecorelli S
,
Santin AD
. HER2/neu as a potential target for immunotherapy in gynecologic carcinosarcomas. Int J Gynecol Pathol. 2012 May; 31(3):211-21.
PMID:
22498937
.
Citations:
10
Fields:
Gyn
Gynecology
Pat
Pathology
Translation:
Humans
Cells
Bellone S, Roque D, Cocco E, Gasparrini S, Bortolomai I, Buza N, Abu-Khalaf M, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S,
Santin AD
. Downregulation of membrane complement inhibitors CD55 and CD59 by siRNA sensitises uterine serous carcinoma overexpressing Her2/neu to complement and antibody-dependent cell cytotoxicity in vitro: implications for trastuzumab-based immunotherapy. Br J Cancer. 2012 Apr 24; 106(9):1543-50.
PMID:
22531721
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Wilken JA
, Badri T, Cross S, Raji R,
Santin AD
, Schwartz P,
Branscum AJ
, Baron AT, Sakhitab AI, Maihle NJ. EGFR/HER-targeted therapeutics in ovarian cancer. Future Med Chem. 2012 Mar; 4(4):447-69.
PMID:
22416774
.
Citations:
25
Fields:
Che
Chemistry
Pha
Pharmacy
Translation:
Humans
El-Sahwi KS, Schwartz PE,
Santin AD
. Development of targeted therapy in uterine serous carcinoma, a biologically aggressive variant of endometrial cancer. Expert Rev Anticancer Ther. 2012 Jan; 12(1):41-9.
PMID:
22149431
.
Citations:
12
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Carrara L, Guzzo F, Roque DM, Bellone S, Emiliano C,
Sartori E
,
Pecorelli S
, Schwartz PE, Rutherford TJ,
Santin AD
. Differential in vitro sensitivity to patupilone versus paclitaxel in uterine and ovarian carcinosarcoma cell lines is linked to tubulin-beta-III expression. Gynecol Oncol. 2012 Apr; 125(1):231-6.
PMID:
22209775
.
Citations:
11
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Ratner ES, Keane FK, Lindner R, Tassi RA, Paranjape T, Glasgow M, Nallur S, Deng Y, Lu L, Steele L, Sand S, Muller RU, Bignotti E, Bellone S, Boeke M, Yao X, Pecorelli S, Ravaggi A, Katsaros D, Zelterman D, Cristea MC, Yu H, Rutherford TJ, Weitzel JN, Neuhausen SL, Schwartz PE, Slack FJ,
Santin AD
, Weidhaas JB. A KRAS variant is a biomarker of poor outcome, platinum chemotherapy resistance and a potential target for therapy in ovarian cancer. Oncogene. 2012 Oct 18; 31(42):4559-66.
PMID:
22139083
.
Citations:
33
Fields:
Mol
Molecular Biology
Neo
Neoplasms
Translation:
Humans
Cells
Bignotti E, Ravaggi A, Romani C, Falchetti M, Lonardi S,
Facchetti F
,
Pecorelli S
, Varughese J, Cocco E, Bellone S, Schwartz PE, Rutherford TJ,
Santin AD
. Trop-2 overexpression in poorly differentiated endometrial endometrioid carcinoma: implications for immunotherapy with hRS7, a humanized anti-trop-2 monoclonal antibody. Int J Gynecol Cancer. 2011 Dec; 21(9):1613-21.
PMID:
21892093
.
Citations:
10
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Raji R, Guzzo F, Carrara L, Varughese J, Cocco E, Bellone S,
Betti M
, Todeschini P, Gasparrini S,
Ratner E
, Silasi DA, Azodi M, Schwartz P, Rutherford TJ, Buza N,
Pecorelli S
,
Santin AD
. Uterine and ovarian carcinosarcomas overexpressing Trop-2 are sensitive to hRS7, a humanized anti-Trop-2 antibody. J Exp Clin Cancer Res. 2011 Nov 10; 30:106.
PMID:
22075385
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Magaldi TG, Almstead LL, Bellone S, Prevatt EG,
Santin AD
,
DiMaio D
. Primary human cervical carcinoma cells require human papillomavirus E6 and E7 expression for ongoing proliferation. Virology. 2012 Jan 05; 422(1):114-24.
PMID:
22056390
.
Citations:
26
Fields:
Vir
Virology
Translation:
Humans
Cells
ElSahwi KS, Hooper C, De Leon MC, Gallo TN,
Ratner E
, Silasi DA,
Santin AD
, Schwartz PE, Rutherford TJ, Azodi M. Comparison between 155 cases of robotic vs. 150 cases of open surgical staging for endometrial cancer. Gynecol Oncol. 2012 Feb; 124(2):260-4.
PMID:
22036203
.
Citations:
17
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Bandiera E, Romani C,
Specchia C
, Zanotti L,
Galli C
, Ruggeri G, Tognon G, Bignotti E, Tassi RA, Odicino F, Caimi L,
Sartori E
,
Santin AD
,
Pecorelli S
, Ravaggi A. Serum human epididymis protein 4 and risk for ovarian malignancy algorithm as new diagnostic and prognostic tools for epithelial ovarian cancer management. Cancer Epidemiol Biomarkers Prev. 2011 Dec; 20(12):2496-506.
PMID:
22028406
.
Citations:
36
Fields:
Bio
Biochemistry
Epi
Epidemiology
Neo
Neoplasms
Translation:
Humans
El-Sahwi KS, Illuzzi J, Varughese J, Carusillo N, Ratner ES, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Santin AD
. A survey of gynecologic oncologists regarding the end-of-life discussion: a pilot study. Gynecol Oncol. 2012 Mar; 124(3):471-3.
PMID:
22014628
.
Citations:
8
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Elsahwi KS, Barber E, Illuzzi J, Buza N,
Ratner E
, Silasi DA,
Santin AD
, Azodi M, Schwartz PE, Rutherford TJ. The significance of perineural invasion in early-stage cervical cancer. Gynecol Oncol. 2011 Dec; 123(3):561-4.
PMID:
21968340
.
Citations:
13
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Todeschini P, Cocco E, Bellone S, Varughese J, Lin K, Carrara L, Guzzo F, Buza N, Hui P, Silasi DA, Ratner E, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S,
Santin AD
. Her2/neu extracellular domain shedding in uterine serous carcinoma: implications for immunotherapy with trastuzumab. Br J Cancer. 2011 Oct 11; 105(8):1176-82.
PMID:
21915118
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Santin AD
, Sill MW, McMeekin DS, Leitao MM,
Brown J
, Sutton GP, Van Le L, Griffin P, Boardman CH. Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: a Gynecologic Oncology Group study. Gynecol Oncol. 2011 Sep; 122(3):495-500.
PMID:
21684583
.
Citations:
30
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Elsahwi KS,
Santin AD
. erbB2 Overexpression in Uterine Serous Cancer: A Molecular Target for Trastuzumab Therapy. Obstet Gynecol Int. 2011; 2011:128295.
PMID:
21876697
.
Citations:
3
Bellone M, Cocco E, Varughese J, Bellone S, Todeschini P, El-Sahwi K, Carrara L, Guzzo F, Schwartz PE, Rutherford TJ,
Pecorelli S
, Marshall DJ,
Santin AD
. Expression of aV-integrins in uterine serous papillary carcinomas; implications for targeted therapy with intetumumab (CNTO 95), a fully human antagonist anti-aV-integrin antibody. Int J Gynecol Cancer. 2011 Aug; 21(6):1084-90.
PMID:
21633302
.
Citations:
6
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Varughese J, Cocco E, Bellone S,
Ratner E
, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Buza N,
Pecorelli S
,
Santin AD
. Cervical carcinomas overexpress human trophoblast cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized monoclonal anti-Trop-2 antibody. Am J Obstet Gynecol. 2011 Dec; 205(6):567.e1-7.
PMID:
21889762
.
Citations:
16
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Cocco E, Varughese J, Buza N, Bellone S, Lin KY, Bellone M, Todeschini P, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Carrara L, Tassi R,
Pecorelli S
,
Lockwood CJ
,
Santin AD
. Tissue factor expression in ovarian cancer: implications for immunotherapy with hI-con1, a factor VII-IgGF(c) chimeric protein targeting tissue factor. Clin Exp Metastasis. 2011 Oct; 28(7):689-700.
PMID:
21725665
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Cocco E, Varughese J, Buza N, Bellone S, Glasgow M, Bellone M, Todeschini P, Carrara L, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Lockwood CJ
,
Santin AD
. Expression of tissue factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix: implications for immunotherapy with hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor. BMC Cancer. 2011 Jun 22; 11:263.
PMID:
21693061
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Casagrande F, Cocco E, Bellone S, Richter CE, Bellone M, Todeschini P, Siegel E, Varughese J, Arin-Silasi D, Azodi M, Rutherford TJ,
Pecorelli S
, Schwartz PE,
Santin AD
. Eradication of chemotherapy-resistant CD44+ human ovarian cancer stem cells in mice by intraperitoneal administration of Clostridium perfringens enterotoxin. Cancer. 2011 Dec 15; 117(24):5519-28.
PMID:
21692061
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Varughese J, Cocco E, Bellone S, Bellone M, Todeschini P, Carrara L, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. High-grade, chemotherapy-resistant primary ovarian carcinoma cell lines overexpress human trophoblast cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized monoclonal anti-Trop-2 antibody. Gynecol Oncol. 2011 Jul; 122(1):171-7.
PMID:
21453957
.
Citations:
18
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Varughese J, Cocco E, Bellone S, de Leon M, Bellone M, Todeschini P, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Uterine serous papillary carcinomas overexpress human trophoblast-cell-surface marker (Trop-2) and are highly sensitive to immunotherapy with hRS7, a humanized anti-Trop-2 monoclonal antibody. Cancer. 2011 Jul 15; 117(14):3163-72.
PMID:
21246534
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Richter CE, Cocco E, Bellone S, Bellone M, Casagrande F, Todeschini P, Rüttinger D, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Primary cervical carcinoma cell lines overexpress epithelial cell adhesion molecule (EpCAM) and are highly sensitive to immunotherapy with MT201, a fully human monoclonal anti-EpCAM antibody. Int J Gynecol Cancer. 2010 Dec; 20(9):1440-7.
PMID:
21370592
.
Citations:
3
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Richter CE, Cocco E, Bellone S, Silasi DA, Rüttinger D, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. High-grade, chemotherapy-resistant ovarian carcinomas overexpress epithelial cell adhesion molecule (EpCAM) and are highly sensitive to immunotherapy with MT201, a fully human monoclonal anti-EpCAM antibody. Am J Obstet Gynecol. 2010 Dec; 203(6):582.e1-7.
PMID:
20870202
.
Citations:
15
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Cocco E, Hu Z, Richter CE, Bellone S, Casagrande F, Bellone M, Todeschini P, Krikun G, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Buza N, Pecorelli S, Lockwood CJ,
Santin AD
. hI-con1, a factor VII-IgGFc chimeric protein targeting tissue factor for immunotherapy of uterine serous papillary carcinoma. Br J Cancer. 2010 Sep 07; 103(6):812-9.
PMID:
20700124
.
Citations:
13
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Paik D, Cocco E, Bellone S, Casagrande F, Bellone M, Siegel EE, Richter CE, Schwartz PE, Rutherford TJ,
Santin AD
. Higher sensitivity to patupilone versus paclitaxel chemotherapy in primary uterine serous papillary carcinoma cell lines with high versus low HER-2/neu expression in vitro. Gynecol Oncol. 2010 Oct; 119(1):140-5.
PMID:
20673976
.
Citations:
6
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Cocco E, Casagrande F, Bellone S, Richter CE, Bellone M, Todeschini P, Holmberg JC, Fu HH, Montagna MK,
Mor G
, Schwartz PE, Arin-Silasi D, Azoudi M, Rutherford TJ, Abu-Khalaf M,
Pecorelli S
,
Santin AD
. Clostridium perfringens enterotoxin carboxy-terminal fragment is a novel tumor-homing peptide for human ovarian cancer. BMC Cancer. 2010 Jul 02; 10:349.
PMID:
20598131
.
Citations:
23
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Cross SN
, Cocco E, Bellone S, Anagnostou VK, Brower SL, Richter CE, Siegel ER, Schwartz PE, Rutherford TJ,
Santin AD
. Differential sensitivity to platinum-based chemotherapy in primary uterine serous papillary carcinoma cell lines with high vs low HER-2/neu expression in vitro. Am J Obstet Gynecol. 2010 Aug; 203(2):162.e1-8.
PMID:
20417484
.
Citations:
10
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Richter CE,
Hui P
, Buza N, Silasi DA, Azodi M,
Santin AD
, Schwartz PE, Rutherford TJ. HER-2/NEU overexpression in vulvar Paget disease: the Yale experience. J Clin Pathol. 2010 Jun; 63(6):544-7.
PMID:
20418225
.
Citations:
13
Fields:
Pat
Pathology
Translation:
Humans
Santin AD
. Letter to the Editor referring to the manuscript entitled: "Phase II trial of trastuzumab in women with advanced or recurrent HER-positive endometrial carcinoma: a Gynecologic Oncology Group study" recently reported by Fleming et al., (Gynecol Oncol., 116;15-20;2010). Gynecol Oncol. 2010 Jul; 118(1):95-6; author reply 96-7.
PMID:
20172595
.
Citations:
13
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Cocco E, Bellone S, El-Sahwi K, Cargnelutti M, Buza N, Tavassoli FA, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Serum amyloid A: a novel biomarker for endometrial cancer. Cancer. 2010 Feb 15; 116(4):843-51.
PMID:
20041483
.
Citations:
33
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Bignotti E, Todeschini P,
Calza S
, Falchetti M, Ravanini M, Tassi RA, Ravaggi A, Bandiera E, Romani C, Zanotti L, Tognon G, Odicino FE,
Facchetti F
,
Pecorelli S
,
Santin AD
. Trop-2 overexpression as an independent marker for poor overall survival in ovarian carcinoma patients. Eur J Cancer. 2010 Mar; 46(5):944-53.
PMID:
20060709
.
Citations:
32
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
El-Sahwi K, Bellone S, Cocco E, Casagrande F, Bellone M, Abu-Khalaf M, Buza N, Tavassoli FA,
Hui P
, Rüttinger D, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Overexpression of EpCAM in uterine serous papillary carcinoma: implications for EpCAM-specific immunotherapy with human monoclonal antibody adecatumumab (MT201). Mol Cancer Ther. 2010 Jan; 9(1):57-66.
PMID:
20053761
.
Citations:
17
Fields:
Ant
Antineoplastic Agents
Translation:
Humans
Cells
El-Sahwi K, Bellone S, Cocco E, Cargnelutti M, Casagrande F, Bellone M, Abu-Khalaf M, Buza N, Tavassoli FA, Hui P, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S,
Santin AD
. In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma. Br J Cancer. 2010 Jan 05; 102(1):134-43.
PMID:
19920829
.
Citations:
44
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Tassi RA,
Calza S
, Ravaggi A, Bignotti E, Odicino FE, Tognon G, Donzelli C, Falchetti M,
Rossi E
, Todeschini P, Romani C, Bandiera E, Zanotti L,
Pecorelli S
,
Santin AD
. Mammaglobin B is an independent prognostic marker in epithelial ovarian cancer and its expression is associated with reduced risk of disease recurrence. BMC Cancer. 2009 Jul 27; 9:253.
PMID:
19635143
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Bellone S, Siegel ER, Cocco E, Cargnelutti M, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Overexpression of epithelial cell adhesion molecule in primary, metastatic, and recurrent/chemotherapy-resistant epithelial ovarian cancer: implications for epithelial cell adhesion molecule-specific immunotherapy. Int J Gynecol Cancer. 2009 Jul; 19(5):860-6.
PMID:
19574774
.
Citations:
47
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Cocco E, Bellone S, El-Sahwi K, Cargnelutti M, Casagrande F, Buza N, Tavassoli FA, Siegel ER, Visintin I, Ratner E, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S,
Santin AD
. Serum amyloid A (SAA): a novel biomarker for uterine serous papillary cancer. Br J Cancer. 2009 Jul 21; 101(2):335-41.
PMID:
19536090
.
Citations:
14
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Romani C, Comper F, Bandiera E, Ravaggi A, Bignotti E, Tassi RA,
Pecorelli S
,
Santin AD
. Development and characterization of a human single-chain antibody fragment against claudin-3: a novel therapeutic target in ovarian and uterine carcinomas. Am J Obstet Gynecol. 2009 Jul; 201(1):70.e1-9.
PMID:
19426958
.
Citations:
10
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Bellone S, El-Sahwi K, Cocco E, Casagrande F, Cargnelutti M, Palmieri M, Bignotti E, Romani C, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Human papillomavirus type 16 (HPV-16) virus-like particle L1-specific CD8+ cytotoxic T lymphocytes (CTLs) are equally effective as E7-specific CD8+ CTLs in killing autologous HPV-16-positive tumor cells in cervical cancer patients: implications for L1 dendritic cell-based therapeutic vaccines. J Virol. 2009 Jul; 83(13):6779-89.
PMID:
19386711
.
Citations:
15
Fields:
Vir
Virology
Translation:
Humans
Cells
Bellone S, Anfossi S, O'Brien TJ, Cannon MJ, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Induction of human tumor-associated differentially expressed gene-12 (TADG-12/TMPRSS3)-specific cytotoxic T lymphocytes in human lymphocyte antigen-A2.1-positive healthy donors and patients with advanced ovarian cancer. Cancer. 2009 Feb 15; 115(4):800-11.
PMID:
19117353
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Bellone S, Anfossi S, O'Brien TJ, Cannon MJ, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ,
Pecorelli S
,
Santin AD
. Generation of CA125-specific cytotoxic T lymphocytes in human leukocyte antigen-A2.1-positive healthy donors and patients with advanced ovarian cancer. Am J Obstet Gynecol. 2009 Jan; 200(1):75.e1-10.
PMID:
18976739
.
Citations:
6
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Bignotti E, Ravaggi A, Tassi RA, Calza S, Rossi E, Falchetti M, Romani C, Bandiera E, Odicino FE, Pecorelli S,
Santin AD
. Trefoil factor 3: a novel serum marker identified by gene expression profiling in high-grade endometrial carcinomas. Br J Cancer. 2008 Sep 02; 99(5):768-73.
PMID:
18682706
.
Citations:
17
Fields:
Neo
Neoplasms
Translation:
Humans
Santin AD
, Bellone S, Roman JJ, McKenney JK,
Pecorelli S
. Trastuzumab treatment in patients with advanced or recurrent endometrial carcinoma overexpressing HER2/neu. Int J Gynaecol Obstet. 2008 Aug; 102(2):128-31.
PMID:
18555254
.
Citations:
53
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Bellone S, Shah HR, McKenney JK, Stone PJ,
Santin AD
. Recurrent endometrial carcinoma regression with the use of the aromatase inhibitor anastrozole. Am J Obstet Gynecol. 2008 Sep; 199(3):e7-e10.
PMID:
18550023
.
Citations:
2
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Wang X,
Santin AD
, Bellone S,
Gupta S
, Nakagawa M. A novel CD4 T-cell epitope described from one of the cervical cancer patients vaccinated with HPV 16 or 18 E7-pulsed dendritic cells. Cancer Immunol Immunother. 2009 Feb; 58(2):301-8.
PMID:
18446336
.
Citations:
8
Fields:
All
Allergy and Immunology
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
CT
Clinical Trials
Tassi RA, Bignotti E, Falchetti M, Ravanini M, Calza S, Ravaggi A, Bandiera E, Facchetti F, Pecorelli S,
Santin AD
. Claudin-7 expression in human epithelial ovarian cancer. Int J Gynecol Cancer. 2008 Nov-Dec; 18(6):1262-71.
PMID:
18298564
.
Citations:
21
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Palmieri M, Zanolini A, Ravaggi A, Siegel ER, Roman JJ,
Pecorelli S
, Cannon MJ. Human papillomavirus type 16 and 18 E7-pulsed dendritic cell vaccination of stage IB or IIA cervical cancer patients: a phase I escalating-dose trial. J Virol. 2008 Feb; 82(4):1968-79.
PMID:
18057249
.
Citations:
51
Fields:
Vir
Virology
Translation:
Humans
Cells
PH
Public Health
CT
Clinical Trials
Tassi RA, Bignotti E, Falchetti M, Calza S, Ravaggi A, Rossi E, Martinelli F, Bandiera E, Pecorelli S,
Santin AD
. Mammaglobin B expression in human endometrial cancer. Int J Gynecol Cancer. 2008 Sep-Oct; 18(5):1090-6.
PMID:
18021217
.
Citations:
12
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Bellone S,
Pecorelli S
, Cannon MJ,
Santin AD
. Advances in dendritic-cell-based therapeutic vaccines for cervical cancer. Expert Rev Anticancer Ther. 2007 Oct; 7(10):1473-86.
PMID:
17944571
.
Citations:
6
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Animals
Cells
Boerma M, Wang J, Burnett AF,
Santin AD
, Roman JJ, Hauer-Jensen M. Local administration of interleukin-11 ameliorates intestinal radiation injury in rats. Cancer Res. 2007 Oct 01; 67(19):9501-6.
PMID:
17909060
.
Citations:
16
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
PH
Public Health
Hardman MP, Roman JJ, Burnett AF,
Santin AD
. Metastatic uterine leiomyosarcoma regression using an aromatase inhibitor. Obstet Gynecol. 2007 Aug; 110(2 Pt 2):518-20.
PMID:
17666649
.
Citations:
8
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Santin AD
, Bellone S, Siegel ER, McKenney JK, Thomas M, Roman JJ, Burnett A, Tognon G, Bandiera E,
Pecorelli S
. Overexpression of Clostridium perfringens enterotoxin receptors claudin-3 and claudin-4 in uterine carcinosarcomas. Clin Cancer Res. 2007 Jun 01; 13(11):3339-46.
PMID:
17545541
.
Citations:
7
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Bellone S, Frera G,
Landolfi G
, Romani C, Bandiera E, Tognon G, Roman JJ, Burnett AF,
Pecorelli S
,
Santin AD
. Overexpression of epidermal growth factor type-1 receptor (EGF-R1) in cervical cancer: implications for Cetuximab-mediated therapy in recurrent/metastatic disease. Gynecol Oncol. 2007 Sep; 106(3):513-20.
PMID:
17540437
.
Citations:
20
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Marizzoni M, Palmieri M, Siegel ER, McKenney JK, Hennings L, Comper F, Bandiera E,
Pecorelli S
. Overexpression of claudin-3 and claudin-4 receptors in uterine serous papillary carcinoma: novel targets for a type-specific therapy using Clostridium perfringens enterotoxin (CPE). Cancer. 2007 Apr 01; 109(7):1312-22.
PMID:
17326053
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Winfield HL, De Las Casas LE, Greenfield WW,
Santin AD
, McKenney JK. Low-grade fibromyxoid sarcoma presenting clinically as a primary ovarian neoplasm: a case report. Int J Gynecol Pathol. 2007 Apr; 26(2):173-6.
PMID:
17413985
.
Citations:
6
Fields:
Gyn
Gynecology
Pat
Pathology
Translation:
Humans
Tassi RA, Bignotti E,
Rossi E
, Falchetti M, Donzelli C,
Calza S
, Ravaggi A, Bandiera E,
Pecorelli S
,
Santin AD
. Overexpression of mammaglobin B in epithelial ovarian carcinomas. Gynecol Oncol. 2007 Jun; 105(3):578-85.
PMID:
17343903
.
Citations:
12
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Bignotti E, Tassi RA,
Calza S
, Ravaggi A, Bandiera E,
Rossi E
, Donzelli C, Pasinetti B,
Pecorelli S
,
Santin AD
. Gene expression profile of ovarian serous papillary carcinomas: identification of metastasis-associated genes. Am J Obstet Gynecol. 2007 Mar; 196(3):245.e1-11.
PMID:
17346539
.
Citations:
35
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Ravindranath MH, Muthugounder S, Presser N, Selvan SR,
Santin AD
, Bellone S, Saravanan TS, Morton DL. Immunogenic gangliosides in human ovarian carcinoma. Biochem Biophys Res Commun. 2007 Feb 09; 353(2):251-8.
PMID:
17188646
.
Citations:
3
Fields:
Bio
Biochemistry
Bio
Biophysics
Translation:
Humans
Cells
Kim KH, Dishongh R,
Santin AD
, Cannon MJ, Bellone S, Nakagawa M. Recognition of a cervical cancer derived tumor cell line by a human papillomavirus type 16 E6 52-61-specific CD8 T cell clone. Cancer Immun. 2006 Jun 30; 6:9.
PMID:
16808432
.
Citations:
7
Fields:
All
Allergy and Immunology
Neo
Neoplasms
Translation:
Humans
Cells
Ravaggi A, Romani C, Pasinetti B, Tassi RA, Bignotti E, Bandiera E, Odicino FE, Ragnoli M, Donzelli C, Falchetti M, Calza S,
Santin AD
, Pecorelli S. Correlation between serological immune response analyzed by a new ELISA for HPV-16/18 E7 oncoprotein and clinical characteristics of cervical cancer patients. Arch Virol. 2006 Oct; 151(10):1899-916.
PMID:
16732494
.
Citations:
10
Fields:
Vir
Virology
Translation:
Humans
PH
Public Health
Bignotti E, Tassi RA,
Calza S
, Ravaggi A, Romani C,
Rossi E
, Falchetti M, Odicino FE,
Pecorelli S
,
Santin AD
. Differential gene expression profiles between tumor biopsies and short-term primary cultures of ovarian serous carcinomas: identification of novel molecular biomarkers for early diagnosis and therapy. Gynecol Oncol. 2006 Nov; 103(2):405-16.
PMID:
16725184
.
Citations:
45
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
,
Diamandis EP
, Bellone S, Marizzoni M, Bandiera E, Palmieri M, Papasakelariou C,
Katsaros D
, Burnett A,
Pecorelli S
. Overexpression of kallikrein 10 (hK10) in uterine serous papillary carcinomas. Am J Obstet Gynecol. 2006 May; 194(5):1296-302.
PMID:
16647913
.
Citations:
6
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Santin AD
, Bellone S, Palmieri M, Ravaggi A, Romani C, Tassi R, Roman JJ, Burnett A,
Pecorelli S
, Cannon MJ. HPV16/18 E7-pulsed dendritic cell vaccination in cervical cancer patients with recurrent disease refractory to standard treatment modalities. Gynecol Oncol. 2006 Mar; 100(3):469-78.
PMID:
16249018
.
Citations:
28
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Van Stedum S, Bushen W, Palmieri M, Siegel ER, De Las Casas LE, Roman JJ, Burnett A,
Pecorelli S
. Amplification of c-erbB2 oncogene: a major prognostic indicator in uterine serous papillary carcinoma. Cancer. 2005 Oct 01; 104(7):1391-7.
PMID:
16116605
.
Citations:
54
Fields:
Neo
Neoplasms
Translation:
Humans
Bellone S, Watts K, Cane' S, Palmieri M, Cannon MJ, Burnett A, Roman JJ,
Pecorelli S
,
Santin AD
. High serum levels of interleukin-6 in endometrial carcinoma are associated with uterine serous papillary histology, a highly aggressive and chemotherapy-resistant variant of endometrial cancer. Gynecol Oncol. 2005 Jul; 98(1):92-8.
PMID:
15904949
.
Citations:
21
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Santin AD
, Bellone S, Van Stedum S, Bushen W, De Las Casas LE, Korourian S, Tian E, Roman JJ, Burnett A,
Pecorelli S
. Determination of HER2/neu status in uterine serous papillary carcinoma: Comparative analysis of immunohistochemistry and fluorescence in situ hybridization. Gynecol Oncol. 2005 Jul; 98(1):24-30.
PMID:
15894362
.
Citations:
34
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Santin AD
, Cané S, Bellone S, Palmieri M, Siegel ER, Thomas M, Roman JJ, Burnett A, Cannon MJ,
Pecorelli S
. Treatment of chemotherapy-resistant human ovarian cancer xenografts in C.B-17/SCID mice by intraperitoneal administration of Clostridium perfringens enterotoxin. Cancer Res. 2005 May 15; 65(10):4334-42.
PMID:
15899825
.
Citations:
39
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Santin AD
,
Diamandis EP
, Bellone S, Soosaipillai A, Cane S, Palmieri M, Burnett A, Roman JJ,
Pecorelli S
. Human kallikrein 6: a new potential serum biomarker for uterine serous papillary cancer. Clin Cancer Res. 2005 May 01; 11(9):3320-5.
PMID:
15867230
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Bondurant KL, Crew MD,
Santin AD
, O'Brien TJ, Cannon MJ. Definition of an immunogenic region within the ovarian tumor antigen stratum corneum chymotryptic enzyme. Clin Cancer Res. 2005 May 01; 11(9):3446-54.
PMID:
15867247
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Zhan F, Cane' S, Bellone S, Palmieri M, Thomas M, Burnett A, Roman JJ, Cannon MJ, Shaughnessy J, Pecorelli S. Gene expression fingerprint of uterine serous papillary carcinoma: identification of novel molecular markers for uterine serous cancer diagnosis and therapy. Br J Cancer. 2005 Apr 25; 92(8):1561-73.
PMID:
15785748
.
Citations:
40
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Siegel ER, Palmieri M, Thomas M, Cannon MJ, Kay HH, Roman JJ, Burnett A,
Pecorelli S
. Racial differences in the overexpression of epidermal growth factor type II receptor (HER2/neu): a major prognostic indicator in uterine serous papillary cancer. Am J Obstet Gynecol. 2005 Mar; 192(3):813-8.
PMID:
15746676
.
Citations:
37
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Santin AD
, Zhan F, Bignotti E, Siegel ER, Cané S, Bellone S, Palmieri M, Anfossi S, Thomas M, Burnett A, Kay HH, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J,
Pecorelli S
. Gene expression profiles of primary HPV16- and HPV18-infected early stage cervical cancers and normal cervical epithelium: identification of novel candidate molecular markers for cervical cancer diagnosis and therapy. Virology. 2005 Jan 20; 331(2):269-91.
PMID:
15629771
.
Citations:
64
Fields:
Vir
Virology
Translation:
Humans
Cells
Santin AD
, Bellone S, Roman JJ, Burnett A, Cannon MJ,
Pecorelli S
. Therapeutic vaccines for cervical cancer: dendritic cell-based immunotherapy. Curr Pharm Des. 2005; 11(27):3485-500.
PMID:
16248803
.
Citations:
17
Fields:
Pha
Pharmacology
Translation:
Humans
Cells
Santin AD
, Zhan F, Bellone S, Palmieri M, Cane S, Bignotti E, Anfossi S, Gokden M, Dunn D, Roman JJ, O'Brien TJ, Tian E, Cannon MJ, Shaughnessy J,
Pecorelli S
. Gene expression profiles in primary ovarian serous papillary tumors and normal ovarian epithelium: identification of candidate molecular markers for ovarian cancer diagnosis and therapy. Int J Cancer. 2004 Oct 20; 112(1):14-25.
PMID:
15305371
.
Citations:
117
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Cane' S, Bellone S, Bignotti E, Palmieri M, De Las Casas LE, Roman JJ, Anfossi S, O'Brien T,
Pecorelli S
. The serine protease stratum corneum chymotryptic enzyme (kallikrein 7) is highly overexpressed in squamous cervical cancer cells. Gynecol Oncol. 2004 Aug; 94(2):283-8.
PMID:
15297163
.
Citations:
8
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Santin AD
, Bellone S, O'Brien TJ,
Pecorelli S
, Cannon MJ, Roman JJ. Current treatment options for endometrial cancer. Expert Rev Anticancer Ther. 2004 Aug; 4(4):679-89.
PMID:
15270671
.
Citations:
4
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Santin AD
, Ravindranath MH, Bellone S, Muthugounder S, Palmieri M, O'Brien TJ, Roman J, Cannon MJ,
Pecorelli S
. Increased levels of gangliosides in the plasma and ascitic fluid of patients with advanced ovarian cancer. BJOG. 2004 Jun; 111(6):613-8.
PMID:
15198791
.
Citations:
7
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
CT
Clinical Trials
Santin AD
, Zhan F, Bellone S, Palmieri M, Cane S, Gokden M, Roman JJ, O'Brien TJ,
Tian E
, Cannon MJ, Shaughnessy J, Pecorelli S. Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling. Br J Cancer. 2004 May 04; 90(9):1814-24.
PMID:
15208622
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Cannon MJ,
Santin AD
, O'Brien TJ. Immunological treatment of ovarian cancer. Curr Opin Obstet Gynecol. 2004 Feb; 16(1):87-92.
PMID:
15128013
.
Citations:
8
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
PH
Public Health
Cané S, Bignotti E, Bellone S, Palmieri M, De las Casas L, Roman JJ,
Pecorelli S
, Cannon MJ, O'brien T,
Santin AD
. The novel serine protease tumor-associated differentially expressed gene-14 (KLK8/Neuropsin/Ovasin) is highly overexpressed in cervical cancer. Am J Obstet Gynecol. 2004 Jan; 190(1):60-6.
PMID:
14749636
.
Citations:
11
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Santin AD
, Bellone S, Palmieri M, Bossini B, Cane' S, Bignotti E, Roman JJ, Cannon MJ, Pecorelli S. Restoration of tumor specific human leukocyte antigens class I-restricted cytotoxicity by dendritic cell stimulation of tumor infiltrating lymphocytes in patients with advanced ovarian cancer. Int J Gynecol Cancer. 2004 Jan-Feb; 14(1):64-75.
PMID:
14764031
.
Citations:
5
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Cane' S, Bellone S, Bignotti E, Palmieri M, De Las Casas LE, Anfossi S, Roman JJ, O'Brien T,
Pecorelli S
. The novel serine protease tumor-associated differentially expressed gene-15 (matriptase/MT-SP1) is highly overexpressed in cervical carcinoma. Cancer. 2003 Nov 01; 98(9):1898-904.
PMID:
14584072
.
Citations:
25
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Bellone S, Palmieri M, Gokden M, Joshua J, Roman JJ,
Pecorelli S
, Cannon MJ,
Santin AD
. Selection of HER-2/neu-positive tumor cells in early stage cervical cancer: implications for Herceptin-mediated therapy. Gynecol Oncol. 2003 Oct; 91(1):231-40.
PMID:
14529687
.
Citations:
6
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Kass R
, Bellone S, Palmieri M,
Canè S
, Bignotti E, Henry-Tillman R, Hutchins L, Cannon MJ, Klimberg S,
Santin AD
. Restoration of tumor-specific HLA class I restricted cytotoxicity in tumor infiltrating lymphocytes of advanced breast cancer patients by in vitro stimulation with tumor antigen-pulsed autologous dendritic cells. Breast Cancer Res Treat. 2003 Aug; 80(3):275-85.
PMID:
14503800
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Parrish RS, Coke C, Dunn D, Roman J, Theus JW, Cannon MJ, Parham GP, Pecorelli S. Influence of allogeneic blood transfusion on clinical outcome during radiotherapy for cancer of the uterine cervix. Gynecol Obstet Invest. 2003; 56(1):28-34.
PMID:
12867765
.
Citations:
9
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Kass R
, Agha J, Bellone S, Palmieri M,
Canè S
, Bignotti E, Henry-Tillman R, Hutchins L, Cannon MJ, Klimberg S,
Santin AD
. In vitro induction of tumor-specific HLA class I-restricted CD8+ cytotoxic T lymphocytes from patients with locally advanced breast cancer by tumor antigen-pulsed autologous dendritic cells. J Surg Res. 2003 Jun 15; 112(2):189-97.
PMID:
12888337
.
Citations:
3
Fields:
Gen
General Surgery
Translation:
Humans
Cells
Santin AD
, Bellone S, Palmieri M, Bossini B, Roman JJ, Cannon MJ, Bignotti E,
Canè S
,
Pecorelli S
. Induction of tumor-specific cytotoxicity in tumor infiltrating lymphocytes by HPV16 and HPV18 E7-pulsed autologous dendritic cells in patients with cancer of the uterine cervix. Gynecol Oncol. 2003 May; 89(2):271-80.
PMID:
12713991
.
Citations:
7
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
CT
Clinical Trials
Santin AD
. HER2/neu overexpression: has the Achilles' heel of uterine serous papillary carcinoma been exposed? Gynecol Oncol. 2003 Mar; 88(3):263-5.
PMID:
12648572
.
Citations:
6
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Santin AD
, Bellone S, Palmieri M, Bossini B, Dunn D, Roman JJ,
Pecorelli S
, Cannon M, Parham GP. Effect of blood transfusion during radiotherapy on the immune function of patients with cancer of the uterine cervix: role of interleukin-10. Int J Radiat Oncol Biol Phys. 2002 Dec 01; 54(5):1345-55.
PMID:
12459356
.
Citations:
11
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Cells
Santin AD
, Bellone S, Gokden M, Cannon MJ, Parham GP. Vaccination with HPV-18 E7-pulsed dendritic cells in a patient with metastatic cervical cancer. N Engl J Med. 2002 May 30; 346(22):1752-3.
PMID:
12037163
.
Citations:
16
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Santin AD
, Bellone S, Gokden M, Palmieri M, Dunn D, Agha J, Roman JJ, Hutchins L,
Pecorelli S
, O'Brien T, Cannon MJ, Parham GP. Overexpression of HER-2/neu in uterine serous papillary cancer. Clin Cancer Res. 2002 May; 8(5):1271-9.
PMID:
12006548
.
Citations:
53
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Underwood LJ, O'Brien TJ, Ravaggi A, Pecorelli S, Cannon MJ. Novel immunotherapeutic strategies in gynecologic oncology. Dendritic cell-based immunotherapy for ovarian cancer. Minerva Ginecol. 2002 Apr; 54(2):133-44.
PMID:
12032451
.
Citations:
2
Fields:
Gyn
Gynecology
Translation:
Humans
Cells
Cannon MJ, O'Brien TJ, Underwood LJ, Crew MD, Bondurant KL,
Santin AD
. Novel target antigens for dendritic cell-based immunotherapy against ovarian cancer. Expert Rev Anticancer Ther. 2002 Feb; 2(1):97-105.
PMID:
12113075
.
Citations:
3
Fields:
Neo
Neoplasms
The
Therapeutics
Translation:
Humans
Cells
Santin AD
, Bellone S, Ravaggi A, Roman JJ, Pecorelli S, Parham GP, Cannon MJ. Induction of tumour-specific CD8(+) cytotoxic T lymphocytes by tumour lysate-pulsed autologous dendritic cells in patients with uterine serous papillary cancer. Br J Cancer. 2002 Jan 07; 86(1):151-7.
PMID:
11857027
.
Citations:
11
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
O'Brien TJ, Beard JB, Underwood LJ, Dennis RA,
Santin AD
, York L. The CA 125 gene: an extracellular superstructure dominated by repeat sequences. Tumour Biol. 2001 Nov-Dec; 22(6):348-66.
PMID:
11786729
.
Citations:
81
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Bellone S, Ravaggi A, Roman J, Smith CV, Pecorelli S, Cannon MJ, Parham GP. Increased levels of interleukin-10 and transforming growth factor-beta in the plasma and ascitic fluid of patients with advanced ovarian cancer. BJOG. 2001 Aug; 108(8):804-8.
PMID:
11510703
.
Citations:
20
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Santin AD
, Ravaggi A, Bellone S, Pecorelli S, Cannon M, Parham GP, Hermonat PL. Tumor-infiltrating lymphocytes contain higher numbers of type 1 cytokine expressors and DR+ T cells compared with lymphocytes from tumor draining lymph nodes and peripheral blood in patients with cancer of the uterine cervix. Gynecol Oncol. 2001 Jun; 81(3):424-32.
PMID:
11371133
.
Citations:
9
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Bellone S, Roman JJ, Jayaprabhu S, Pecorelli S, Parham GP, Cannon MJ. Expression of CD56 by human papillomavirus E7-specific CD8+ cytotoxic T lymphocytes correlates with increased intracellular perforin expression and enhanced cytotoxicity against HLA-A2-matched cervical tumor cells. Clin Cancer Res. 2001 Mar; 7(3 Suppl):804s-810s.
PMID:
11300476
.
Citations:
12
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Clemons-Miller AR, Chatta GS, Hutchins L, Angtuaco EJ, Ravaggi A,
Santin AD
, Cannon MJ. Intrathecal cytotoxic T-cell immunotherapy for metastatic leptomeningeal melanoma. Clin Cancer Res. 2001 Mar; 7(3 Suppl):917s-924s.
PMID:
11300492
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Bellone S, Roman JJ, Smith CV, Pecorelli S, Radominska-Pandya A, Cannon MJ, Parham GP. Phenotypic and functional analysis of tumor-infiltrating lymphocytes compared with tumor-associated lymphocytes from ascitic fluid and peripheral blood lymphocytes in patients with advanced ovarian cancer. Gynecol Obstet Invest. 2001; 51(4):254-61.
PMID:
11408737
.
Citations:
30
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Bellone S, Roman J, Pecorelli S, Cannon M, Parham GP. Effects of concurrent cisplatinum administration during radiotherapy vs. radiotherapy alone on the immune function of patients with cancer of the uterine cervix. Int J Radiat Oncol Biol Phys. 2000 Nov 01; 48(4):997-1006.
PMID:
11072156
.
Citations:
21
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Cells
CT
Clinical Trials
Santin AD
, Bellone S, Ravaggi A, Pecorelli S, Cannon MJ, Parham GP. Induction of ovarian tumor-specific CD8+ cytotoxic T lymphocytes by acid-eluted peptide-pulsed autologous dendritic cells. Obstet Gynecol. 2000 Sep; 96(3):422-30.
PMID:
10960637
.
Citations:
18
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Bellone S, Pecorelli S, Cannon MJ, Parham GP. In vitro induction of tumor-specific human lymphocyte antigen class I-restricted CD8 cytotoxic T lymphocytes by ovarian tumor antigen-pulsed autologous dendritic cells from patients with advanced ovarian cancer. Am J Obstet Gynecol. 2000 Sep; 183(3):601-9.
PMID:
10992180
.
Citations:
8
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Bellone S, Pecorelli S, Roman JJ, Parham GP, Cannon MJ. Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8(+) cytotoxic T lymphocytes. J Virol. 2000 May; 74(10):4729-37.
PMID:
10775611
.
Citations:
49
Fields:
Vir
Virology
Translation:
Humans
Cells
Hermonat PL,
Santin AD
, Zhan D. Binding of the human papillomavirus type 16 E7 oncoprotein and the adeno-associated virus Rep78 major regulatory protein in vitro and in yeast and the potential for downstream effects. J Hum Virol. 2000 May-Jun; 3(3):113-24.
PMID:
10881991
.
Citations:
4
Fields:
Vir
Virology
Translation:
Humans
Animals
Cells
Santin AD
, Hermonat PL, Ravaggi A, Bellone S, Cowan C, Korourian S, Pecorelli S, Cannon MJ, Parham GP. Development, characterization and distribution of adoptively transferred peripheral blood lymphocytes primed by human papillomavirus 18 E7--pulsed autologous dendritic cells in a patient with metastatic adenocarcinoma of the uterine cervix. Eur J Gynaecol Oncol. 2000; 21(1):17-23.
PMID:
10726612
.
Citations:
5
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
. Lymph node metastases: the importance of the microenvironment. Cancer. 2000 Jan 01; 88(1):175-9.
PMID:
10618621
.
Citations:
5
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Liu Y,
Santin AD
, Mane M, Chiriva-Internati M, Parham GP, Ravaggi A, Hermonat PL. Transduction and utility of the granulocyte-macrophage colony-stimulating factor gene into monocytes and dendritic cells by adeno-associated virus. J Interferon Cytokine Res. 2000 Jan; 20(1):21-30.
PMID:
10670649
.
Citations:
13
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Bellone S, Cowan C, Coke C, Pecorelli S, Cannon MJ, Parham GP. Development and therapeutic effect of adoptively transferred T cells primed by tumor lysate-pulsed autologous dendritic cells in a patient with metastatic endometrial cancer. Gynecol Obstet Invest. 2000; 49(3):194-203.
PMID:
10729762
.
Citations:
7
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Hermonat PL,
Santin AD
, De Greve J, De Rijcke M, Bishop BM, Han L, Mane M, Kokorina N. Chromosomal latency and expression at map unit 96 of a wild-type plus adeno-associated virus (AAV)/Neo vector and identification of p81, a new AAV transcriptional promoter. J Hum Virol. 1999 Nov-Dec; 2(6):359-68.
PMID:
10774553
.
Citations:
5
Fields:
Vir
Virology
Translation:
Humans
Cells
Zhan D,
Santin AD
, Liu Y, Parham GP, Li C,
Meyers C
, Hermonat PL. Binding of the human papillomavirus type 16 p97 promoter by the adeno-associated virus Rep78 major regulatory protein correlates with inhibition. J Biol Chem. 1999 Oct 29; 274(44):31619-24.
PMID:
10531369
.
Citations:
12
Fields:
Bio
Biochemistry
Translation:
Cells
Santin AD
, Hermonat PL, Ravaggi A, Chiriva-Internati M, Zhan D, Pecorelli S, Parham GP, Cannon MJ. Induction of human papillomavirus-specific CD4(+) and CD8(+) lymphocytes by E7-pulsed autologous dendritic cells in patients with human papillomavirus type 16- and 18-positive cervical cancer. J Virol. 1999 Jul; 73(7):5402-10.
PMID:
10364287
.
Citations:
33
Fields:
Vir
Virology
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Pecorelli S, Cannon MJ, Parham GP. Secretion of vascular endothelial growth factor in adenocarcinoma and squamous cell carcinoma of the uterine cervix. Obstet Gynecol. 1999 Jul; 94(1):78-82.
PMID:
10389722
.
Citations:
4
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Chiriva-Internati M, Cannon MJ, Hiserodt JC, Pecorelli S, Parham GP. Expression of surface antigens during the differentiation of human dendritic cells vs macrophages from blood monocytes in vitro. Immunobiology. 1999 Jun; 200(2):187-204.
PMID:
10416127
.
Citations:
12
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Cannon MJ, Pecorelli S, Parham GP. Secretion of vascular endothelial growth factor in ovarian cancer. Eur J Gynaecol Oncol. 1999; 20(3):177-81.
PMID:
10410879
.
Citations:
32
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Chiriva-Internati M, Pecorelli S, Parham GP. Radiation-enhanced expression of E6/E7 transforming oncogenes of human papillomavirus-16 in human cervical carcinoma. Cancer. 1998 Dec 01; 83(11):2346-52.
PMID:
9840534
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Kokorina NA,
Santin AD
, Li C, Hermonat PL. Involvement of protein-DNA interaction in adeno-associated virus Rep78-mediated inhibition of HIV-1. J Hum Virol. 1998 Nov-Dec; 1(7):441-50.
PMID:
10195265
.
Citations:
6
Fields:
Vir
Virology
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Chiriva-Internati M, Pecorelli S, Parham GP. Retinoic acid up-regulates the expression of major histocompatibility complex molecules and adhesion/costimulation molecules (specifically, intercellular adhesion molecule ICAM-1) in human cervical cancer. Am J Obstet Gynecol. 1998 Oct; 179(4):1020-5.
PMID:
9790391
.
Citations:
4
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Cells
Hermonat PL,
Meyers C
, Parham GP,
Santin AD
. Inhibition/stimulation of bovine papillomavirus by adeno-associated virus is time as well as multiplicity dependent. Virology. 1998 Aug 01; 247(2):240-50.
PMID:
9705917
.
Citations:
3
Fields:
Vir
Virology
Translation:
Animals
Cells
Santin AD
, Hermonat PL, Ravaggi A, Chiriva-Internati M, Hiserodt JC, Pecorelli S, Parham GP. Effects of retinoic acid combined with irradiation on the expression of major histocompatibility complex molecules and adhesion/costimulation molecules ICAM-1 in human cervical cancer. Gynecol Oncol. 1998 Aug; 70(2):195-201.
PMID:
9740690
.
Citations:
4
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Ravaggi A, Chiriva-Internati M, Hiserodt JC, Batchu RB, Pecorelli S, Parham GP. The effects of irradiation on the expression of a tumour rejection antigen (heat shock protein gp96) in human cervical cancer. Int J Radiat Biol. 1998 Jun; 73(6):699-704.
PMID:
9690688
.
Citations:
6
Fields:
Rad
Radiology
Translation:
Humans
Cells
Hermonat PL,
Santin AD
, Batchu RB, Zhan D. The adeno-associated virus Rep78 major regulatory protein binds the cellular TATA-binding protein in vitro and in vivo. Virology. 1998 May 25; 245(1):120-7.
PMID:
9614873
.
Citations:
18
Fields:
Vir
Virology
Translation:
Humans
Cells
Santin AD
, Hermonat P, Ravaggi A, Chiriva-Internati M, Hiserodt JC,
Tian E
, Carter CA, Pecorelli S, Parham GP. Effects of retinoic acid combined with interferon-gamma on the expression of major-histocompatibility-complex molecules and intercellular adhesion molecule-1 in human cervical cancer. Int J Cancer. 1998 Jan 19; 75(2):254-8.
PMID:
9462716
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Parham GP. Routine lymph node dissection in the treatment of early stage cancer: are we doing the right thing? Gynecol Oncol. 1998 Jan; 68(1):1-3.
PMID:
9454650
.
Citations:
2
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Santin AD
, Hermonat PL, Ravaggi A, Chiriva-Internati M, Pecorelli S, Parham GP. Effects of retinoic acid on the expression of a tumor rejection antigen (heat shock protein gp96) in human cervical cancer. Eur J Gynaecol Oncol. 1998; 19(3):229-33.
PMID:
9641219
.
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Hiserodt JC, Chiriva-Internati M, Woodliff J, Theus JW, Barclay D, Pecorelli S, Parham GP. Effects of irradiation on the expression of major histocompatibility complex class I antigen and adhesion costimulation molecules ICAM-1 in human cervical cancer. Int J Radiat Oncol Biol Phys. 1997 Oct 01; 39(3):737-42.
PMID:
9336157
.
Citations:
17
Fields:
Neo
Neoplasms
Rad
Radiology
Rad
Radiotherapy
Translation:
Humans
Cells
Hermonat PL,
Santin AD
, Carter CA, Parham GP, Quirk JG. Multiple cellular proteins are recognized by the adeno-associated virus Rep78 major regulatory protein and the amino-half of Rep78 is required for many of these interactions. Biochem Mol Biol Int. 1997 Oct; 43(2):409-20.
PMID:
9350349
.
Citations:
1
Fields:
Bio
Biochemistry
Mol
Molecular Biology
Translation:
Humans
Cells
Hermonat PL, Plott RT,
Santin AD
, Parham GP, Flick JT. Adeno-associated virus Rep78 inhibits oncogenic transformation of primary human keratinocytes by a human papillomavirus type 16-ras chimeric. Gynecol Oncol. 1997 Sep; 66(3):487-94.
PMID:
9299265
.
Citations:
13
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Hermonat PL, Hiserodt JC, Fruehauf J, Schranz V, Barclay D, Pecorelli S, Parham GP. Differential transforming growth factor-beta secretion in adenocarcinoma and squamous cell carcinoma of the uterine cervix. Gynecol Oncol. 1997 Mar; 64(3):477-80.
PMID:
9062154
.
Citations:
4
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Hermonat PL,
Santin AD
, Batchu RB. The adeno-associated virus Rep78 major regulatory/transformation suppressor protein binds cellular Sp1 in vitro and evidence of a biological effect. Cancer Res. 1996 Nov 15; 56(22):5299-304.
PMID:
8912872
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Bishop BM,
Santin AD
, Quirk JG, Hermonat PL. Role of the terminal repeat GAGC trimer, the major Rep78 binding site, in adeno-associated virus DNA replication. FEBS Lett. 1996 Nov 11; 397(1):97-100.
PMID:
8941722
.
Citations:
4
Fields:
Bio
Biochemistry
Translation:
Cells
Rose GS, Tocco LM, Granger GA, DiSaia PJ, Hamilton TC,
Santin AD
, Hiserodt JC. Development and characterization of a clinically useful animal model of epithelial ovarian cancer in the Fischer 344 rat. Am J Obstet Gynecol. 1996 Sep; 175(3 Pt 1):593-9.
PMID:
8828419
.
Citations:
12
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Animals
Cells
Santin AD
, Hiserodt JC, DiSaia PJ, Pecorelli S, Granger GA. Differential effects of high-dose gamma irradiation on the production of transforming growth factor-beta in fresh and established human ovarian cancer. Gynecol Oncol. 1996 Jun; 61(3):403-8.
PMID:
8641623
.
Citations:
2
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Rose GS, Hiserodt JC, Fruehauf J, Eck LM, Garcia RI, Schranz V, Disaia PJ, Pecorelli S, Granger GA. Effects of cytokines combined with high-dose gamma irradiation on the expression of major histocompatibility complex molecules and intercellular adhesion molecule-1 in human ovarian cancers. Int J Cancer. 1996 Mar 01; 65(5):688-94.
PMID:
8598323
.
Citations:
10
Fields:
Neo
Neoplasms
Translation:
Humans
Santin AD
, Hiserodt JC, Fruehauf J, DiSaia PJ, Pecorelli S, Granger GA. Effects of irradiation on the expression of surface antigens in human ovarian cancer. Gynecol Oncol. 1996 Mar; 60(3):468-74.
PMID:
8774659
.
Citations:
13
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
Santin AD
, Ioli GR, Hiserodt JC, Manetta A, Pecorelli S, DiSaia PJ, Granger GA. Development and characterization of an interleukin-2-transduced human ovarian carcinoma tumor vaccine not expressing major histocompatibility complex molecules. Am J Obstet Gynecol. 1996 Feb; 174(2):633-40.
PMID:
8623798
.
Citations:
Fields:
Gyn
Gynecology
Obs
Obstetrics
Translation:
Humans
Animals
Cells
Santin AD
, Ioli GR, Hiserodt JC, Rose GS, Graf MR, Tocco LM, Lander JK, Eck LM, Burger RA, DiSaia PJ, et al. Development and characterization of an IL-4-secreting human ovarian carcinoma cell line. Gynecol Oncol. 1995 Aug; 58(2):230-9.
PMID:
7622110
.
Citations:
2
Fields:
Gyn
Gynecology
Neo
Neoplasms
Translation:
Humans
Cells
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