James L Boyer

InstitutionDepartment of Medicine
AddressUnited States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 1 Covid-19 publications, with a maximum of 1 publications in June 2021
    All Publications
    Bar chart showing 107 publications over 19 distinct years, with a maximum of 10 publications in 2002 and 2006 and 2010
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Citations: 8   Article has an altmetric score of 24    Fields:    Translation:Humans
    2. Boyer JL. Harold J. Fallon, M.D. (1931-2018). Hepatology. 2019 05; 69(5):2308-2309. PMID: 30811607.
      Fields:    
    3. Cai SY, Boyer JL. Bile Infarcts: New Insights Into the Pathogenesis of Obstructive Cholestasis. Hepatology. 2019 02; 69(2):473-475. PMID: 30251326.
      Fields:    Translation:HumansCells
    4. Soroka CJ, Assis DN, Boyer JL. Patient-Derived Organoids from Human Bile: An In Vitro Method to Study Cholangiopathies. Methods Mol Biol. 2019; 1981:363-372. PMID: 31016667.
      Citations: 2   Fields:    Translation:HumansCells
    5. Jiang Y, Huang Y, Cai S, Song Y, Boyer JL, Zhang K, Gao L, Zhao J, Huang W, Liang G, Liangpunsakul S, Wang L. H19 Is Expressed in Hybrid Hepatocyte Nuclear Factor 4a+ Periportal Hepatocytes but Not Cytokeratin 19+ Cholangiocytes in Cholestatic Livers. Hepatol Commun. 2018 Nov; 2(11):1356-1368. PMID: 30411082.
      Citations: 3   
    6. Pan Q, Zhang X, Zhang L, Cheng Y, Zhao N, Li F, Zhou X, Chen S, Li J, Xu S, Huang D, Chen Y, Li L, Wang H, Chen W, Cai SY, Boyer JL, Chai J. Solute Carrier Organic Anion Transporter Family Member 3A1 Is a Bile Acid Efflux Transporter in Cholestasis. Gastroenterology. 2018 11; 155(5):1578-1592.e16. PMID: 30063921.
      Citations: 7   Article has an altmetric score of 1    Fields:    Translation:HumansAnimalsCells
    7. Gurung A, Assis DN, McCarty TR, Mitchell KA, Boyer JL, Jain D. Histologic features of autoimmune hepatitis: a critical appraisal. Hum Pathol. 2018 12; 82:51-60. PMID: 30041025.
      Citations: 11   Article has an altmetric score of 13    Fields:    Translation:HumansCells
    8. Yu D, Cai SY, Mennone A, Vig P, Boyer JL. Cenicriviroc, a cytokine receptor antagonist, potentiates all-trans retinoic acid in reducing liver injury in cholestatic rodents. Liver Int. 2018 06; 38(6):1128-1138. PMID: 29356312.
      Citations: 15   Article has an altmetric score of 4    Fields:    Translation:Animals
    9. Boyer JL. OSTa-OSTß Guards the Ileal Enterocyte From the Accumulation of Toxic Levels of Bile Acids. Cell Mol Gastroenterol Hepatol. 2018; 5(4):649-650. PMID: 29713669.
      Citations: 2   Fields:    
    10. Goldberg DS, Levy C, Yimam K, Gordon SC, Forman L, Verna E, Yu L, Rahimi R, Schwarz K, Eksteen B, Pratt D, Boyer JL, Assis D, Bowlus C. Primary Sclerosing Cholangitis Is Not Rare Among Blacks in a Multicenter North American Consortium. Clin Gastroenterol Hepatol. 2018 04; 16(4):591-593. PMID: 29102704.
      Citations: 2   Article has an altmetric score of 4    Fields:    Translation:Humans
    11. Li M, Cai SY, Boyer JL. Mechanisms of bile acid mediated inflammation in the liver. Mol Aspects Med. 2017 08; 56:45-53. PMID: 28606651.
      Citations: 33   Fields:    Translation:HumansAnimalsCells
    12. Cai SY, Boyer JL. Studies on the mechanisms of bile acid initiated hepatic inflammation in cholestatic liver injury. Inflamm Cell Signal. 2017; 4(2). PMID: 28804737.
      Citations: 3   
    13. Boyer JL. Maintaining a Vibrant and Productive Laboratory as a Senior Investigator. Cell Mol Gastroenterol Hepatol. 2017 Sep; 4(2):299-300. PMID: 28840184.
      Citations: Article has an altmetric score of 2    Fields:    
    14. Cai SY, Ouyang X, Chen Y, Soroka CJ, Wang J, Mennone A, Wang Y, Mehal WZ, Jain D, Boyer JL. Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response. JCI Insight. 2017 03 09; 2(5):e90780. PMID: 28289714.
      Citations: 69   Article has an altmetric score of 4    Fields:    Translation:HumansAnimalsCells
    15. Cai SY, Boyer JL. The Role of Inflammation in the Mechanisms of Bile Acid-Induced Liver Damage. Dig Dis. 2017; 35(3):232-234. PMID: 28249287.
      Citations: 7   Article has an altmetric score of 3    Fields:    Translation:HumansAnimalsCells
    16. Assis DN, Abdelghany O, Cai SY, Gossard AA, Eaton JE, Keach JC, Deng Y, Setchell KD, Ciarleglio M, Lindor KD, Boyer JL. Combination Therapy of All-Trans Retinoic Acid With Ursodeoxycholic Acid in Patients With Primary Sclerosing Cholangitis: A Human Pilot Study. J Clin Gastroenterol. 2017 Feb; 51(2):e11-e16. PMID: 27428727.
      Citations: 13   Article has an altmetric score of 4    Fields:    Translation:HumansCTClinical Trials
    17. Yu D, Zhang H, Lionarons DA, Boyer JL, Cai SY. Na+-taurocholate cotransporting polypeptide (NTCP/SLC10A1) ortholog in the marine skate Leucoraja erinacea is not a physiological bile salt transporter. Am J Physiol Regul Integr Comp Physiol. 2017 04 01; 312(4):R477-R484. PMID: 28077388.
      Translation:HumansAnimalsCells
    18. Boyer JL. Treatment of chronic cholestasis: What we know and what we will know? Clin Liver Dis (Hoboken). 2016 Dec; 8(6):140-144. PMID: 31041082.
      Citations: Article has an altmetric score of 1    
    19. Li M, Soroka CJ, Harry K, Boyer JL. CFTR-associated ligand is a negative regulator of Mrp2 expression. Am J Physiol Cell Physiol. 2017 Jan 01; 312(1):C40-C46. PMID: 27834195.
      Citations: 1   Article has an altmetric score of 1    Translation:HumansAnimalsCells
    20. Kulkarni SR, Soroka CJ, Hagey LR, Boyer JL. Sirtuin 1 activation alleviates cholestatic liver injury in a cholic acid-fed mouse model of cholestasis. Hepatology. 2016 12; 64(6):2151-2164. PMID: 27639250.
      Citations: 19   Article has an altmetric score of 1    Fields:    Translation:Animals
    21. Assis DN, Takahashi H, Leng L, Zeniya M, Boyer JL, Bucala R. A Macrophage Migration Inhibitory Factor Polymorphism Is Associated with Autoimmune Hepatitis Severity in US and Japanese Patients. Dig Dis Sci. 2016 12; 61(12):3506-3512. PMID: 27696094.
      Citations: 10   Article has an altmetric score of 3    Fields:    Translation:Humans
    22. Xu S, Soroka CJ, Sun AQ, Backos DS, Mennone A, Suchy FJ, Boyer JL. A Novel Di-Leucine Motif at the N-Terminus of Human Organic Solute Transporter Beta Is Essential for Protein Association and Membrane Localization. PLoS One. 2016; 11(6):e0158269. PMID: 27351185.
      Citations: 4   Fields:    Translation:HumansCells
    23. Li M, Mennone A, Soroka CJ, Hagey LR, Ouyang X, Weinman EJ, Boyer JL. Na(+) /H(+) exchanger regulatory factor 1 knockout mice have an attenuated hepatic inflammatory response and are protected from cholestatic liver injury. Hepatology. 2015 Oct; 62(4):1227-36. PMID: 26108984.
      Citations: 9   Article has an altmetric score of 2    Fields:    Translation:Animals
    24. Chai J, Cai SY, Liu X, Lian W, Chen S, Zhang L, Feng X, Cheng Y, He X, He Y, Chen L, Wang R, Wang H, Boyer JL, Chen W. Canalicular membrane MRP2/ABCC2 internalization is determined by Ezrin Thr567 phosphorylation in human obstructive cholestasis. J Hepatol. 2015 Dec; 63(6):1440-8. PMID: 26212029.
      Citations: 14   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    25. Ghonem NS, Assis DN, Boyer JL. Fibrates and cholestasis. Hepatology. 2015 Aug; 62(2):635-43. PMID: 25678132.
      Citations: 55   Article has an altmetric score of 214    Fields:    Translation:Humans
    26. Boyer JL. The origins of hepatobiliary and gastrointestinal physiology. Hepatology. 2015 May; 61(5):1452-4. PMID: 25677183.
      Citations: Article has an altmetric score of 2    Fields:    Translation:Humans
    27. Perry RJ, Zhang D, Zhang XM, Boyer JL, Shulman GI. Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats. Science. 2015 Mar 13; 347(6227):1253-6. PMID: 25721504.
      Citations: 100   Article has an altmetric score of 207    Fields:    Translation:AnimalsCells
    28. Boyer JL. The hepatobiliary paracellular pathway: a paradigm revisited. Gastroenterology. 2014 Nov; 147(5):965-8. PMID: 25263297.
      Citations: 1   Fields:    Translation:HumansAnimalsCells
    29. Mistry PK, Liu J, Sun L, Chuang WL, Yuen T, Yang R, Lu P, Zhang K, Li J, Keutzer J, Stachnik A, Mennone A, Boyer JL, Jain D, Brady RO, New MI, Zaidi M. Glucocerebrosidase 2 gene deletion rescues type 1 Gaucher disease. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):4934-9. PMID: 24639522.
      Citations: 40   Article has an altmetric score of 3    Fields:    Translation:HumansAnimalsCells
    30. Cai SY, Mennone A, Soroka CJ, Boyer JL. All-trans-retinoic acid improves cholestasis in a-naphthylisothiocyanate-treated rats and Mdr2-/- mice. J Pharmacol Exp Ther. 2014 Apr; 349(1):94-8. PMID: 24492652.
      Citations: 6   Fields:    Translation:Animals
    31. Cai SY, Mennone A, Soroka CJ, Boyer JL. Altered expression and function of canalicular transporters during early development of cholestatic liver injury in Abcb4-deficient mice. Am J Physiol Gastrointest Liver Physiol. 2014 Apr 15; 306(8):G670-6. PMID: 24481602.
      Citations: 10   Fields:    Translation:Animals
    32. Ghonem NS, Ananthanarayanan M, Soroka CJ, Boyer JL. Peroxisome proliferator-activated receptor a activates human multidrug resistance transporter 3/ATP-binding cassette protein subfamily B4 transcription and increases rat biliary phosphatidylcholine secretion. Hepatology. 2014 Mar; 59(3):1030-42. PMID: 24122873.
      Citations: 22   Article has an altmetric score of 7    Fields:    Translation:HumansAnimalsCells
    33. Wheeler SG, Hammond CL, Jornayvaz FR, Samuel VT, Shulman GI, Soroka CJ, Boyer JL, Hinkle PM, Ballatori N. Osta-/- mice exhibit altered expression of intestinal lipid absorption genes, resistance to age-related weight gain, and modestly improved insulin sensitivity. Am J Physiol Gastrointest Liver Physiol. 2014 Mar 01; 306(5):G425-38. PMID: 24381083.
      Citations: 8   Fields:    Translation:Animals
    34. Assis DN, Leng L, Du X, Zhang CK, Grieb G, Merk M, Garcia AB, McCrann C, Chapiro J, Meinhardt A, Mizue Y, Nikolic-Paterson DJ, Bernhagen J, Kaplan MM, Zhao H, Boyer JL, Bucala R. The role of macrophage migration inhibitory factor in autoimmune liver disease. Hepatology. 2014 Feb; 59(2):580-91. PMID: 23913513.
      Citations: 39   Article has an altmetric score of 8    Fields:    Translation:HumansCells
    35. Weerachayaphorn J, Luo Y, Mennone A, Soroka CJ, Harry K, Boyer JL. Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice. J Hepatol. 2014 Jan; 60(1):160-6. PMID: 23978715.
      Citations: 15   Article has an altmetric score of 3    Fields:    Translation:Animals
    36. Boyer JL. Bile formation and secretion. Compr Physiol. 2013 Jul; 3(3):1035-78. PMID: 23897680.
      Citations: 169   Article has an altmetric score of 101    Fields:    Translation:HumansAnimalsCells
    37. Cai SY, Lionarons DA, Hagey L, Soroka CJ, Mennone A, Boyer JL. Adult sea lamprey tolerates biliary atresia by altering bile salt composition and renal excretion. Hepatology. 2013 Jun; 57(6):2418-26. PMID: 23175353.
      Citations: 10   Article has an altmetric score of 1    Fields:    Translation:Animals
    38. Soroka CJ, Boyer JL. Biosynthesis and trafficking of the bile salt export pump, BSEP: therapeutic implications of BSEP mutations. Mol Aspects Med. 2014 Jun; 37:3-14. PMID: 23685087.
      Citations: 11   Fields:    Translation:HumansCells
    39. Ghonem NS, Boyer JL. Fibrates as adjuvant therapy for chronic cholestatic liver disease: its time has come. Hepatology. 2013 May; 57(5):1691-3. PMID: 23174993.
      Citations: 11   Article has an altmetric score of 3    Fields:    Translation:Humans
    40. Lionarons DA, Boyer JL, Cai SY. Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2). J Lipid Res. 2012 Aug; 53(8):1535-42. PMID: 22669917.
      Citations: 15   Fields:    Translation:HumansAnimalsCells
    41. Chai J, He Y, Cai SY, Jiang Z, Wang H, Li Q, Chen L, Peng Z, He X, Wu X, Xiao T, Wang R, Boyer JL, Chen W. Elevated hepatic multidrug resistance-associated protein 3/ATP-binding cassette subfamily C 3 expression in human obstructive cholestasis is mediated through tumor necrosis factor alpha and c-Jun NH2-terminal kinase/stress-activated protein kinase-signaling pathway. Hepatology. 2012 May; 55(5):1485-94. PMID: 22105759.
      Citations: 32   Fields:    Translation:HumansCells
    42. Boyer JL, Soroka CJ. A cholecystohepatic shunt pathway: does the gallbladder protect the liver? Gastroenterology. 2012 Jun; 142(7):1416-9. PMID: 22542828.
      Citations: 4   Fields:    Translation:Animals
    43. Lam P, Xu S, Soroka CJ, Boyer JL. A C-terminal tyrosine-based motif in the bile salt export pump directs clathrin-dependent endocytosis. Hepatology. 2012 Jun; 55(6):1901-11. PMID: 22161577.
      Citations: 12   Fields:    Translation:HumansAnimalsCells
    44. Weerachayaphorn J, Mennone A, Soroka CJ, Harry K, Hagey LR, Kensler TW, Boyer JL. Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Am J Physiol Gastrointest Liver Physiol. 2012 May 01; 302(9):G925-36. PMID: 22345550.
      Citations: 25   Fields:    Translation:Animals
    45. Soroka CJ, Velazquez H, Mennone A, Ballatori N, Boyer JL. Osta depletion protects liver from oral bile acid load. Am J Physiol Gastrointest Liver Physiol. 2011 Sep; 301(3):G574-9. PMID: 21719738.
      Citations: 13   Fields:    Translation:Animals
    46. Padda MS, Sanchez M, Akhtar AJ, Boyer JL. Drug-induced cholestasis. Hepatology. 2011 Apr; 53(4):1377-87. PMID: 21480339.
      Citations: 85   Article has an altmetric score of 14    Fields:    Translation:Humans
    47. Ghatak S, Biswas A, Dhali GK, Chowdhury A, Boyer JL, Santra A. Oxidative stress and hepatic stellate cell activation are key events in arsenic induced liver fibrosis in mice. Toxicol Appl Pharmacol. 2011 Feb 15; 251(1):59-69. PMID: 21134390.
      Citations: 31   Fields:    Translation:AnimalsCells
    48. McCrann CH, Boyer JL. Small-duct sclerosing cholangitis associated with Schistosoma mansoni. Hepatology. 2011 Feb; 53(2):712-3. PMID: 20882579.
      Citations: 1   Fields:    Translation:HumansAnimals
    49. Srivastava S, Boyer JL. Psychological stress is associated with relapse in type 1 autoimmune hepatitis. Liver Int. 2010 Nov; 30(10):1439-47. PMID: 20849437.
      Citations: 8   Article has an altmetric score of 6    Fields:    Translation:Humans
    50. Mennone A, Soroka CJ, Harry KM, Boyer JL. Role of breast cancer resistance protein in the adaptive response to cholestasis. Drug Metab Dispos. 2010 Oct; 38(10):1673-8. PMID: 20601550.
      Citations: 14   Fields:    Translation:Animals
    51. Lam P, Soroka CJ, Boyer JL. The bile salt export pump: clinical and experimental aspects of genetic and acquired cholestatic liver disease. Semin Liver Dis. 2010 May; 30(2):125-33. PMID: 20422495.
      Citations: 27   Fields:    Translation:HumansAnimalsCells
    52. Soroka CJ, Ballatori N, Boyer JL. Organic solute transporter, OSTalpha-OSTbeta: its role in bile acid transport and cholestasis. Semin Liver Dis. 2010 May; 30(2):178-85. PMID: 20422499.
      Citations: 25   Fields:    Translation:HumansAnimals
    53. Boyer JL. Cholestasis: genetic and acquired. Semin Liver Dis. 2010 May; 30(2):113-5. PMID: 20422493.
      Fields:    Translation:HumansCells
    54. Li M, Wang W, Soroka CJ, Mennone A, Harry K, Weinman EJ, Boyer JL. NHERF-1 binds to Mrp2 and regulates hepatic Mrp2 expression and function. J Biol Chem. 2010 Jun 18; 285(25):19299-307. PMID: 20404332.
      Citations: 23   Fields:    Translation:HumansAnimalsCells
    55. Xu S, Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL. Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Am J Physiol Gastrointest Liver Physiol. 2010 Jul; 299(1):G126-35. PMID: 20395535.
      Citations: 25   Article has an altmetric score of 4    Fields:    Translation:HumansAnimalsCells
    56. Soroka CJ, Mennone A, Hagey LR, Ballatori N, Boyer JL. Mouse organic solute transporter alpha deficiency enhances renal excretion of bile acids and attenuates cholestasis. Hepatology. 2010 Jan; 51(1):181-90. PMID: 19902485.
      Citations: 30   Fields:    Translation:Animals
    57. Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL. Nuclear factor erythroid 2-related factor 2 is a positive regulator of human bile salt export pump expression. Hepatology. 2009 Nov; 50(5):1588-96. PMID: 19821532.
      Citations: 29   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    58. Thomas DJ, Nava GM, Cai SY, Boyer JL, Hernández-Zavala A, Gaskins HR. Arsenic (+ 3 oxidation state) methyltransferase and the methylation of arsenicals in the invertebrate chordate Ciona intestinalis. Toxicol Sci. 2010 Jan; 113(1):70-6. PMID: 19833739.
      Citations: 10   Fields:    Translation:AnimalsCells
    59. Boyer JL. It's all about bile. Hepatology. 2009 Mar; 49(3):711-23. PMID: 19242972.
      Citations: 1   Article has an altmetric score of 3    Fields:    Translation:HumansAnimals
    60. Ballatori N, Li N, Fang F, Boyer JL, Christian WV, Hammond CL. OST alpha-OST beta: a key membrane transporter of bile acids and conjugated steroids. Front Biosci (Landmark Ed). 2009 01 01; 14(8):2829-44. PMID: 19273238.
      Citations: 37   Article has an altmetric score of 3    Fields:    Translation:HumansCells
    61. Madejczyk MS, Boyer JL, Ballatori N. Hepatic uptake and biliary excretion of manganese in the little skate, Leucoraja erinacea. Comp Biochem Physiol C Toxicol Pharmacol. 2009 May; 149(4):566-71. PMID: 19141331.
      Citations: 5   Fields:    Translation:AnimalsCells
    62. Wang L, Dong H, Soroka CJ, Wei N, Boyer JL, Hochstrasser M. Degradation of the bile salt export pump at endoplasmic reticulum in progressive familial intrahepatic cholestasis type II. Hepatology. 2008 Nov; 48(5):1558-69. PMID: 18798335.
      Citations: 33   Fields:    Translation:HumansCells
    63. Cai SY, Gautam S, Nguyen T, Soroka CJ, Rahner C, Boyer JL. ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained. Gastroenterology. 2009 Mar; 136(3):1060-9. PMID: 19027009.
      Citations: 33   Article has an altmetric score of 1    Fields:    Translation:HumansAnimalsCells
    64. Soroka CJ, Xu S, Mennone A, Lam P, Boyer JL. N-Glycosylation of the alpha subunit does not influence trafficking or functional activity of the human organic solute transporter alpha/beta. BMC Cell Biol. 2008 Oct 10; 9:57. PMID: 18847488.
      Citations: 8   Fields:    Translation:HumansAnimalsCells
    65. Boyer JL. Bile canalicular secretion - tales from Vienna and Yale. Wien Med Wochenschr. 2008; 158(19-20):534-8. PMID: 18998067.
      Fields:    Translation:HumansAnimalsCells
    66. Lam P, Pearson CL, Soroka CJ, Xu S, Mennone A, Boyer JL. Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases. Am J Physiol Cell Physiol. 2007 Nov; 293(5):C1709-16. PMID: 17855769.
      Citations: 30   Article has an altmetric score of 6    Translation:HumansAnimalsCells
    67. Sun AQ, Ponamgi VM, Boyer JL, Suchy FJ. Membrane trafficking of the human organic anion-transporting polypeptide C (hOATPC). Pharm Res. 2008 Feb; 25(2):463-74. PMID: 17641954.
      Citations: 6   Fields:    Translation:HumansAnimalsCells
    68. Cai SY, Xiong L, Wray CG, Ballatori N, Boyer JL. The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution. Am J Physiol Regul Integr Comp Physiol. 2007 Sep; 293(3):R1400-9. PMID: 17567710.
      Citations: 20   Translation:HumansAnimals
    69. Tradtrantip L, Piyachaturawat P, Soroka CJ, Harry K, Mennone A, Mahagita C, Ballatori N, Boyer JL. Phloracetophenone-induced choleresis in rats is mediated through Mrp2. Am J Physiol Gastrointest Liver Physiol. 2007 Jul; 293(1):G66-74. PMID: 17363469.
      Citations: 2   Fields:    Translation:Animals
    70. Chen W, Cai SY, Xu S, Denson LA, Soroka CJ, Boyer JL. Nuclear receptors RXRalpha:RARalpha are repressors for human MRP3 expression. Am J Physiol Gastrointest Liver Physiol. 2007 May; 292(5):G1221-7. PMID: 17272513.
      Citations: 8   Fields:    Translation:HumansCells
    71. Boyer JL. New perspectives for the treatment of cholestasis: lessons from basic science applied clinically. J Hepatol. 2007 Mar; 46(3):365-71. PMID: 17223219.
      Citations: 23   Fields:    Translation:HumansAnimals
    72. Wang W, Soroka CJ, Mennone A, Rahner C, Harry K, Pypaert M, Boyer JL. Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes. Gastroenterology. 2006 Sep; 131(3):878-84. PMID: 16952556.
      Citations: 43   Fields:    Translation:AnimalsCells
    73. Tradtrantip L, Boyer JL, Suksamrarn A, Piyachaturawat P. Differential effects of hydroxyacetophenone analogues on the transcytotic vesicular pathway in rat liver. Eur J Pharmacol. 2006 Oct 10; 547(1-3):152-9. PMID: 16945364.
      Fields:    Translation:AnimalsCells
    74. Cai SY, Boyer JL. FXR: a target for cholestatic syndromes? Expert Opin Ther Targets. 2006 Jun; 10(3):409-21. PMID: 16706681.
      Citations: 11   Article has an altmetric score of 9    Fields:    Translation:HumansAnimals
    75. Villanueva SS, Ruiz ML, Soroka CJ, Cai SY, Luquita MG, Torres AM, Sánchez Pozzi EJ, Pellegrino JM, Boyer JL, Catania VA, Mottino AD. Hepatic and extrahepatic synthesis and disposition of dinitrophenyl-S-glutathione in bile duct-ligated rats. Drug Metab Dispos. 2006 Aug; 34(8):1301-9. PMID: 16679389.
      Citations: 5   Fields:    Translation:AnimalsCells
    76. Mattingly CJ, Rosenstein MC, Davis AP, Colby GT, Forrest JN, Boyer JL. The comparative toxicogenomics database: a cross-species resource for building chemical-gene interaction networks. Toxicol Sci. 2006 Aug; 92(2):587-95. PMID: 16675512.
      Citations: 45   Article has an altmetric score of 9    Fields:    Translation:HumansAnimals
    77. Mennone A, Soroka CJ, Cai SY, Harry K, Adachi M, Hagey L, Schuetz JD, Boyer JL. Mrp4-/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology. 2006 May; 43(5):1013-21. PMID: 16628672.
      Citations: 63   Fields:    Translation:Animals
    78. Denk GU, Cai SY, Chen WS, Lin A, Soroka CJ, Boyer JL. A comparison of gene expression in mouse liver and kidney in obstructive cholestasis utilizing high-density oligonucleotide microarray technology. World J Gastroenterol. 2006 Apr 28; 12(16):2536-48. PMID: 16688799.
      Citations: 3   Fields:    Translation:Animals
    79. Ballatori N, Henson JH, Seward DJ, Cai SY, Runnegar M, Fricker G, Miller DS, Boyer JL. Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis. Comp Biochem Physiol B Biochem Mol Biol. 2006 Jun; 144(2):167-79. PMID: 16567119.
      Citations: 2   Fields:    Translation:AnimalsCells
    80. Boyer JL, Trauner M, Mennone A, Soroka CJ, Cai SY, Moustafa T, Zollner G, Lee JY, Ballatori N. Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents. Am J Physiol Gastrointest Liver Physiol. 2006 Jun; 290(6):G1124-30. PMID: 16423920.
      Citations: 97   Article has an altmetric score of 6    Fields:    Translation:HumansAnimalsCells
    81. Ballatori N, Christian WV, Lee JY, Dawson PA, Soroka CJ, Boyer JL, Madejczyk MS, Li N. OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology. 2005 Dec; 42(6):1270-9. PMID: 16317684.
      Citations: 106   Article has an altmetric score of 4    Fields:    Translation:HumansAnimalsCells
    82. Combes B, Emerson SS, Flye NL, Munoz SJ, Luketic VA, Mayo MJ, McCashland TM, Zetterman RK, Peters MG, Di Bisceglie AM, Benner KG, Kowdley KV, Carithers RL, Rosoff L, Garcia-Tsao G, Boyer JL, Boyer TD, Martinez EJ, Bass NM, Lake JR, Barnes DS, Bonacini M, Lindsay KL, Mills AS, Markin RS, Rubin R, West AB, Wheeler DE, Contos MJ, Hofmann AF. Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis. Hepatology. 2005 Nov; 42(5):1184-93. PMID: 16250039.
      Citations: 34   Article has an altmetric score of 12    Fields:    Translation:Humans
    83. Seela S, Sheela H, Boyer JL. Autoimmune hepatitis type 1: safety and efficacy of prolonged medical therapy. Liver Int. 2005 Aug; 25(4):734-9. PMID: 15998423.
      Citations: 10   Article has an altmetric score of 6    Fields:    Translation:Humans
    84. Sheela H, Seela S, Caldwell C, Boyer JL, Jain D. Liver biopsy: evolving role in the new millennium. J Clin Gastroenterol. 2005 Aug; 39(7):603-10. PMID: 16000929.
      Citations: 11   Fields:    Translation:Humans
    85. Boyer JL. Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease? Gastroenterology. 2005 Aug; 129(2):735-40. PMID: 16083726.
      Citations: 23   Fields:    Translation:HumansAnimals
    86. Denk GU, Soroka CJ, Mennone A, Koepsell H, Beuers U, Boyer JL. Down-regulation of the organic cation transporter 1 of rat liver in obstructive cholestasis. Hepatology. 2004 May; 39(5):1382-9. PMID: 15122767.
      Citations: 22   Fields:    Translation:AnimalsCells
    87. Trauner M, Boyer JL. Cholestatic syndromes. Curr Opin Gastroenterol. 2004 May; 20(3):220-30. PMID: 15703646.
      Citations: 6   Fields:    
    88. Denk GU, Soroka CJ, Takeyama Y, Chen WS, Schuetz JD, Boyer JL. Multidrug resistance-associated protein 4 is up-regulated in liver but down-regulated in kidney in obstructive cholestasis in the rat. J Hepatol. 2004 Apr; 40(4):585-91. PMID: 15030973.
      Citations: 39   Fields:    Translation:AnimalsCells
    89. Wang L, Boyer JL. The maintenance and generation of membrane polarity in hepatocytes. Hepatology. 2004 Apr; 39(4):892-9. PMID: 15057889.
      Citations: 34   Article has an altmetric score of 3    Fields:    Translation:HumansAnimalsCells
    90. Bohan A, Chen WS, Denson LA, Held MA, Boyer JL. Tumor necrosis factor alpha-dependent up-regulation of Lrh-1 and Mrp3(Abcc3) reduces liver injury in obstructive cholestasis. J Biol Chem. 2003 Sep 19; 278(38):36688-98. PMID: 12837754.
      Citations: 47   Fields:    Translation:HumansAnimalsCells
    91. Mattingly CJ, Colby GT, Forrest JN, Boyer JL. The Comparative Toxicogenomics Database (CTD). Environ Health Perspect. 2003 May; 111(6):793-5. PMID: 12760826.
      Citations: 60   Article has an altmetric score of 6    Fields:    Translation:HumansAnimals
    92. Trauner M, Boyer JL. Cholestatic syndromes. Curr Opin Gastroenterol. 2003 May; 19(3):216-31. PMID: 15703562.
      Citations: 2   Fields:    
    93. Seward DJ, Koh AS, Boyer JL, Ballatori N. Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta. J Biol Chem. 2003 Jul 25; 278(30):27473-82. PMID: 12719432.
      Citations: 52   Article has an altmetric score of 6    Fields:    Translation:HumansAnimalsCells
    94. Trauner M, Boyer JL. Bile salt transporters: molecular characterization, function, and regulation. Physiol Rev. 2003 Apr; 83(2):633-71. PMID: 12663868.
      Citations: 227   Article has an altmetric score of 6    Fields:    Translation:HumansAnimals
    95. Beuers U, Denk GU, Soroka CJ, Wimmer R, Rust C, Paumgartner G, Boyer JL. Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets. J Biol Chem. 2003 May 16; 278(20):17810-8. PMID: 12626520.
      Citations: 24   Article has an altmetric score of 6    Fields:    Translation:AnimalsCells
    96. Arrese M, Trauner M, Ananthanarayanan M, Pizarro M, Solís N, Accatino L, Soroka C, Boyer JL, Karpen SJ, Miquel JF, Suchy FJ. Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat. J Hepatol. 2003 Feb; 38(2):148-55. PMID: 12547402.
      Citations: 10   Fields:    Translation:AnimalsCells
    97. Ballatori N, Boyer JL, Rockett JC. Exploiting genome data to understand the function, regulation, and evolutionary origins of toxicologically relevant genes. EHP Toxicogenomics. 2003 Jan; 111(1T):61-5. PMID: 12735111.
      Citations: 7   Fields:    Translation:HumansAnimals
    98. Boyer JL. A biliary milestone: functional expression of the human bile salt export pump. Gastroenterology. 2002 Nov; 123(5):1733-5. PMID: 12404248.
      Citations: 1   Fields:    Translation:HumansAnimals
    99. Cai SY, Soroka CJ, Ballatori N, Boyer JL. Molecular characterization of a multidrug resistance-associated protein, Mrp2, from the little skate. Am J Physiol Regul Integr Comp Physiol. 2003 Jan; 284(1):R125-30. PMID: 12388433.
      Citations: 10   Translation:HumansAnimalsCells
    100. Wang L, Soroka CJ, Boyer JL. The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II. J Clin Invest. 2002 Oct; 110(7):965-72. PMID: 12370274.
      Citations: 31   Article has an altmetric score of 6    Fields:    Translation:HumansAnimalsCells
    101. Mennone A, Verkman AS, Boyer JL. Unimpaired osmotic water permeability and fluid secretion in bile duct epithelia of AQP1 null mice. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3):G739-46. PMID: 12181190.
      Citations: 9   Fields:    Translation:AnimalsCells
    102. Denson LA, Bohan A, Held MA, Boyer JL. Organ-specific alterations in RAR alpha:RXR alpha abundance regulate rat Mrp2 (Abcc2) expression in obstructive cholestasis. Gastroenterology. 2002 Aug; 123(2):599-607. PMID: 12145812.
      Citations: 18   Fields:    Translation:AnimalsCells
    103. Azzaroli F, Mehal W, Soroka CJ, Wang L, Lee J, Crispe IN, Crispe N, Boyer JL. Ursodeoxycholic acid diminishes Fas-ligand-induced apoptosis in mouse hepatocytes. Hepatology. 2002 Jul; 36(1):49-54. PMID: 12085348.
      Citations: 12   Fields:    Translation:AnimalsCells
    104. Trauner M, Boyer JL. Cholestatic syndromes. Curr Opin Gastroenterol. 2002 May; 18(3):314-29. PMID: 17033302.
      Fields:    
    105. Cai SY, Wang W, Soroka CJ, Ballatori N, Boyer JL. An evolutionarily ancient Oatp: insights into conserved functional domains of these proteins. Am J Physiol Gastrointest Liver Physiol. 2002 Apr; 282(4):G702-10. PMID: 11897630.
      Citations: 9   Fields:    Translation:HumansAnimalsCells
    106. Bohan A, Boyer JL. Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions. Semin Liver Dis. 2002; 22(2):123-36. PMID: 12016544.
      Citations: 14   Article has an altmetric score of 3    Fields:    Translation:HumansAnimals
    107. Boyer JL. Sperber I. Secretion of organic anions in the formation of urine and bile[Pharmacol. Rev. 1959;11:109-134]. J Hepatol. 2002 Jan; 36(1):4-7. PMID: 11804657.
      Fields:    Translation:HumansAnimals