David K Meyerholz

InstitutionUNIVERSITY OF IOWA
AddressIowa City
Iowa
United States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 15 Covid-19 publications, with a maximum of 2 publications in Spetember 2020 and June 2021 and July 2021
    All Publications
    Bar chart showing 195 publications over 21 distinct years, with a maximum of 19 publications in 2016
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li K, Meyerholz DK, Bartlett JA, McCray PB. The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19. mBio. 2021 08 31; 12(4):e0097021. PMID: 34340553.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    2. Dampalla CS, Zheng J, Perera KD, Wong LR, Meyerholz DK, Nguyen HN, Kashipathy MM, Battaile KP, Lovell S, Kim Y, Perlman S, Groutas WC, Chang KO. Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection. Proc Natl Acad Sci U S A. 2021 07 20; 118(29). PMID: 34210738.
      Citations: 6     Fields:    Translation:AnimalsCells
    3. An D, Li K, Rowe DK, Diaz MCH, Griffin EF, Beavis AC, Johnson SK, Padykula I, Jones CA, Briggs K, Li G, Lin Y, Huang J, Mousa J, Brindley M, Sakamoto K, Meyerholz DK, McCray PB, Tompkins SM, He B. Protection of K18-hACE2 mice and ferrets against SARS-CoV-2 challenge by a single-dose mucosal immunization with a parainfluenza virus 5-based COVID-19 vaccine. Sci Adv. 2021 Jul; 7(27). PMID: 34215591.
      Citations: 7     Fields:    
    4. Wong LR, Zheng J, Sariol A, Lowery S, Meyerholz DK, Gallagher T, Perlman S. Middle East respiratory syndrome coronavirus Spike protein variants exhibit geographic differences in virulence. Proc Natl Acad Sci U S A. 2021 06 15; 118(24). PMID: 34099556.
      Citations: 1     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    5. Zheng J, Meyerholz D, Wong LR, Gelb M, Murakami M, Perlman S. Coronavirus-specific antibody production in middle-aged mice requires phospholipase A2G2D. J Clin Invest. 2021 06 01; 131(11). PMID: 34060490.
      Citations:    Fields:    Translation:AnimalsCells
    6. Zheng J, Wang Y, Li K, Meyerholz DK, Allamargot C, Perlman S. Severe Acute Respiratory Syndrome Coronavirus 2-Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells. J Infect Dis. 2021 03 03; 223(5):785-795. PMID: 33277988.
      Citations: 27     Fields:    Translation:HumansCells
    7. Meyerholz DK, Perlman S. Does common cold coronavirus infection protect against severe SARS-CoV-2 disease? J Clin Invest. 2021 01 04; 131(1). PMID: 33216734.
      Citations: 3     Fields:    Translation:HumansPHPublic Health
    8. Zheng J, Wong LR, Li K, Verma AK, Ortiz ME, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB, Perlman S. COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Nature. 2021 01; 589(7843):603-607. PMID: 33166988.
      Citations: 72     Fields:    Translation:HumansAnimals
    9. Ortiz ME, Thurman A, Pezzulo AA, Leidinger MR, Klesney-Tait JA, Karp PH, Tan P, Wohlford-Lenane C, McCray PB, Meyerholz DK. Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract. EBioMedicine. 2020 Oct; 60:102976. PMID: 32971472.
      Citations: 53     Fields:    Translation:HumansCellsPHPublic Health
    10. Sariol A, Mackin S, Allred MG, Ma C, Zhou Y, Zhang Q, Zou X, Abrahante JE, Meyerholz DK, Perlman S. Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection. Proc Natl Acad Sci U S A. 2020 09 29; 117(39):24464-24474. PMID: 32929007.
      Citations: 11     Fields:    Translation:AnimalsCells
    11. Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO. 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med. 2020 08 19; 12(557). PMID: 32747425.
      Citations: 52     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. Meyerholz DK, McCray PB. Illuminating COVID-19 lung disease through autopsy studies. EBioMedicine. 2020 Jul; 57:102865. PMID: 32629393.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    13. Sun J, Zhuang Z, Zheng J, Li K, Wong RL, Liu D, Huang J, He J, Zhu A, Zhao J, Li X, Xi Y, Chen R, Alshukairi AN, Chen Z, Zhang Z, Chen C, Huang X, Li F, Lai X, Chen D, Wen L, Zhuo J, Zhang Y, Wang Y, Huang S, Dai J, Shi Y, Zheng K, Leidinger MR, Chen J, Li Y, Zhong N, Meyerholz DK, McCray PB, Perlman S, Zhao J. Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment. Cell. 2020 08 06; 182(3):734-743.e5. PMID: 32643603.
      Citations: 148     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    14. Li K, Li Z, Wohlford-Lenane C, Meyerholz DK, Channappanavar R, An D, Perlman S, McCray PB, He B. Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection. mBio. 2020 04 07; 11(2). PMID: 32265331.
      Citations: 21     Fields:    Translation:AnimalsCellsPHPublic Health
    15. Meyerholz DK, Beck AP. Histopathologic Evaluation and Scoring of Viral Lung Infection. Methods Mol Biol. 2020; 2099:205-220. PMID: 31883098.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    16. Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray PB, Meyerholz DK, Perlman S. IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. J Clin Invest. 2019 07 29; 129(9):3625-3639. PMID: 31355779.
      Citations: 206     Fields:    Translation:HumansAnimalsCells
    17. Hua X, Vijay R, Channappanavar R, Athmer J, Meyerholz DK, Pagedar N, Tilley S, Perlman S. Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia. JCI Insight. 2018 06 07; 3(11). PMID: 29875310.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    18. Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, Nicholls JM, Meyerholz DK, Kuranga SA, Mamo G, Zhou Z, So RTY, Hemida MG, Webby RJ, Roger F, Rambaut A, Poon LLM, Perlman S, Drosten C, Chevalier V, Peiris M. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):3144-3149. PMID: 29507189.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    19. Wheeler DL, Sariol A, Meyerholz DK, Perlman S. Microglia are required for protection against lethal coronavirus encephalitis in mice. J Clin Invest. 2018 03 01; 128(3):931-943. PMID: 29376888.
      Citations: 62     Fields:    Translation:AnimalsCells
    20. Wheeler DL, Athmer J, Meyerholz DK, Perlman S. Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus. J Virol. 2017 Nov 15; 91(22). PMID: 28835503.
      Citations: 11     Fields:    
    21. Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):E5444-E5453. PMID: 28630327.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    22. Channappanavar R, Fett C, Mack M, Ten Eyck PP, Meyerholz DK, Perlman S. Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. J Immunol. 2017 05 15; 198(10):4046-4053. PMID: 28373583.
      Citations: 282     Fields:    Translation:AnimalsCells
    23. Li K, Wohlford-Lenane CL, Channappanavar R, Park JE, Earnest JT, Bair TB, Bates AM, Brogden KA, Flaherty HA, Gallagher T, Meyerholz DK, Perlman S, McCray PB. Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice. Proc Natl Acad Sci U S A. 2017 04 11; 114(15):E3119-E3128. PMID: 28348219.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    24. Fehr AR, Channappanavar R, Jankevicius G, Fett C, Zhao J, Athmer J, Meyerholz DK, Ahel I, Perlman S. The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection. mBio. 2016 12 13; 7(6). PMID: 27965448.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    25. Zhao J, Zhao J, Mangalam AK, Channappanavar R, Fett C, Meyerholz DK, Agnihothram S, Baric RS, David CS, Perlman S. Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses. Immunity. 2016 06 21; 44(6):1379-91. PMID: 27287409.
      Citations: 180     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    26. Meyerholz DK. Modeling Emergent Diseases: Lessons From Middle East Respiratory Syndrome. Vet Pathol. 2016 May; 53(3):517-8. PMID: 27000399.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    27. Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, Perlman S. Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice. Cell Host Microbe. 2016 Feb 10; 19(2):181-93. PMID: 26867177.
      Citations: 603     Translation:HumansAnimalsCells
    28. Meyerholz DK, Lambertz AM, McCray PB. Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory Syndrome. Am J Pathol. 2016 Jan; 186(1):78-86. PMID: 26597880.
      Citations: 68     Fields:    Translation:Humans
    29. Li K, Wohlford-Lenane C, Perlman S, Zhao J, Jewell AK, Reznikov LR, Gibson-Corley KN, Meyerholz DK, McCray PB. Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4. J Infect Dis. 2016 Mar 01; 213(5):712-22. PMID: 26486634.
      Citations: 186     Fields:    Translation:HumansAnimalsCells
    30. Vijay R, Hua X, Meyerholz DK, Miki Y, Yamamoto K, Gelb M, Murakami M, Perlman S. Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection. J Exp Med. 2015 Oct 19; 212(11):1851-68. PMID: 26392224.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    31. Channappanavar R, Lu L, Xia S, Du L, Meyerholz DK, Perlman S, Jiang S. Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection. J Infect Dis. 2015 Dec 15; 212(12):1894-903. PMID: 26164863.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    32. Zhao J, Perera RA, Kayali G, Meyerholz D, Perlman S, Peiris M. Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection. J Virol. 2015 Jun; 89(11):6117-20. PMID: 25787284.
      Citations: 39     Fields:    Translation:AnimalsCells
    33. Fehr AR, Athmer J, Channappanavar R, Phillips JM, Meyerholz DK, Perlman S. The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis. J Virol. 2015 Feb; 89(3):1523-36. PMID: 25428866.
      Citations: 63     Fields:    Translation:AnimalsCells
    34. Channappanavar R, Fett C, Zhao J, Meyerholz DK, Perlman S. Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection. J Virol. 2014 Oct; 88(19):11034-44. PMID: 25056892.
      Citations: 179     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    35. O'Keefe BR, Giomarelli B, Barnard DL, Shenoy SR, Chan PK, McMahon JB, Palmer KE, Barnett BW, Meyerholz DK, Wohlford-Lenane CL, McCray PB. Broad-spectrum in vitro activity and in vivo efficacy of the antiviral protein griffithsin against emerging viruses of the family Coronaviridae. J Virol. 2010 Mar; 84(5):2511-21. PMID: 20032190.
      Citations: 138     Fields:    Translation:HumansAnimalsCells
    36. Wohlford-Lenane CL, Meyerholz DK, Perlman S, Zhou H, Tran D, Selsted ME, McCray PB. Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. J Virol. 2009 Nov; 83(21):11385-90. PMID: 19710146.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    37. Khanolkar A, Hartwig SM, Haag BA, Meyerholz DK, Epping LL, Haring JS, Varga SM, Harty JT. Protective and pathologic roles of the immune response to mouse hepatitis virus type 1: implications for severe acute respiratory syndrome. J Virol. 2009 Sep; 83(18):9258-72. PMID: 19570864.
      Citations: 22     Fields:    Translation:AnimalsCells
    38. Khanolkar A, Hartwig SM, Haag BA, Meyerholz DK, Harty JT, Varga SM. Toll-like receptor 4 deficiency increases disease and mortality after mouse hepatitis virus type 1 infection of susceptible C3H mice. J Virol. 2009 Sep; 83(17):8946-56. PMID: 19553337.
      Citations: 32     Fields:    Translation:AnimalsCells
    39. Netland J, Meyerholz DK, Moore S, Cassell M, Perlman S. Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2. J Virol. 2008 Aug; 82(15):7264-75. PMID: 18495771.
      Citations: 494     Fields:    Translation:HumansAnimalsCells
    40. McCray PB, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S. Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. J Virol. 2007 Jan; 81(2):813-21. PMID: 17079315.
      Citations: 344     Fields:    Translation:HumansAnimalsCells
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