Laurent Renia

InstitutionAgency for Science
AddressSingapore
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 25 Covid-19 publications, with a maximum of 3 publications in July 2020 and August 2020 and October 2020 and April 2021
    All Publications
    Bar chart showing 214 publications over 20 distinct years, with a maximum of 23 publications in 2017
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

    To see the data from both graphs as text, click here.
    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
    Sort By:     Newest   |   Oldest   |   Most Cited   |   Most Discussed
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Young BE, Ong SWX, Ng LFP, Anderson DE, Chia WN, Chia PY, Ang LW, Mak TM, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Fong SW, Chan YH, Tan CW, Lee B, Rötzschke O, Ding Y, Tambyah P, Low JGH, Cui L, Barkham T, Lin RTP, Leo YS, Renia L, Wang LF, Lye DC. Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity. Clin Infect Dis. 2021 11 02; 73(9):e2932-e2942. PMID: 32856707.
      Citations: 39     Fields:    Translation:Humans
    2. Chan YH, Young BE, Fong SW, Ding Y, Goh YS, Chee RS, Tan SY, Kalimuddin S, Tambyah PA, Leo YS, Ng LFP, Lye DC, Renia L. Differential Cytokine Responses in Hospitalized COVID-19 Patients Limit Efficacy of Remdesivir. Front Immunol. 2021; 12:680188. PMID: 34262564.
      Citations:    Fields:    Translation:Humans
    3. Goh YS, Ng LFP, Renia L. A flow cytometry-based assay for serological detection of anti-spike antibodies in COVID-19 patients. STAR Protoc. 2021 09 17; 2(3):100671. PMID: 34179835.
      Citations:    
    4. Chan YH, Fong SW, Poh CM, Carissimo G, Yeo NK, Amrun SN, Goh YS, Lim J, Xu W, Chee RS, Torres-Ruesta A, Lee CY, Tay MZ, Chang ZW, Lee WH, Wang B, Tan SY, Kalimuddin S, Young BE, Leo YS, Wang CI, Lee B, Rötzschke O, Lye DC, Renia L, Ng LFP. Asymptomatic COVID-19: disease tolerance with efficient anti-viral immunity against SARS-CoV-2. EMBO Mol Med. 2021 06 07; 13(6):e14045. PMID: 33961735.
      Citations: 6     Fields:    Translation:HumansCells
    5. Dalan R, Ang LW, Tan WYT, Fong SW, Tay WC, Chan YH, Renia L, Ng LFP, Lye DC, Chew DEK, Young BE. The association of hypertension and diabetes pharmacotherapy with COVID-19 severity and immune signatures: an observational study. Eur Heart J Cardiovasc Pharmacother. 2021 05 23; 7(3):e48-e51. PMID: 32766831.
      Citations: 20     Fields:    Translation:Humans
    6. Asarnow D, Wang B, Lee WH, Hu Y, Huang CW, Faust B, Ng PML, Ngoh EZX, Bohn M, Bulkley D, Pizzorno A, Ary B, Tan HC, Lee CY, Minhat RA, Terrier O, Soh MK, Teo FJ, Yeap YYC, Seah SGK, Chan CEZ, Connelly E, Young NJ, Maurer-Stroh S, Renia L, Hanson BJ, Rosa-Calatrava M, Manglik A, Cheng Y, Craik CS, Wang CI. Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia. Cell. 2021 06 10; 184(12):3192-3204.e16. PMID: 33974910.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    7. Young BE, Wei WE, Fong SW, Mak TM, Anderson DE, Chan YH, Pung R, Heng CS, Ang LW, Zheng AKE, Lee B, Kalimuddin S, Pada S, Tambyah PA, Parthasarathy P, Tan SY, Sun L, Smith GJ, Lin RTP, Leo YS, Renia L, Wang LF, Ng LF, Maurer-Stroh S, Lye DC, Lee VJ. Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study. EBioMedicine. 2021 Apr; 66:103319. PMID: 33840632.
      Citations: 6     Fields:    Translation:Humans
    8. Ong SWX, Fong SW, Young BE, Chan YH, Lee B, Amrun SN, Chee RS, Yeo NK, Tambyah P, Pada S, Tan SY, Ding Y, Renia L, Leo YS, Ng LFP, Lye DC. Persistent Symptoms and Association With Inflammatory Cytokine Signatures in Recovered Coronavirus Disease 2019 Patients. Open Forum Infect Dis. 2021 Jun; 8(6):ofab156. PMID: 34095336.
      Citations: 6     
    9. Chioh FW, Fong SW, Young BE, Wu KX, Siau A, Krishnan S, Chan YH, Carissimo G, Teo LL, Gao F, Tan RS, Zhong L, Koh AS, Tan SY, Tambyah PA, Renia L, Ng LF, Lye DC, Cheung C. Convalescent COVID-19 patients are susceptible to endothelial dysfunction due to persistent immune activation. Elife. 2021 03 23; 10. PMID: 33752798.
      Citations: 12     Fields:    Translation:HumansCells
    10. Chia WN, Zhu F, Ong SWX, Young BE, Fong SW, Le Bert N, Tan CW, Tiu C, Zhang J, Tan SY, Pada S, Chan YH, Tham CYL, Kunasegaran K, Chen MI, Low JGH, Leo YS, Renia L, Bertoletti A, Ng LFP, Lye DC, Wang LF. Dynamics of SARS-CoV-2 neutralising antibody responses and duration of immunity: a longitudinal study. Lancet Microbe. 2021 Jun; 2(6):e240-e249. PMID: 33778792.
      Citations: 65     
    11. Lee CY, Amrun SN, Chee RS, Goh YS, Mak TM, Octavia S, Yeo NK, Chang ZW, Tay MZ, Torres-Ruesta A, Carissimo G, Poh CM, Fong SW, Bei W, Lee S, Young BE, Tan SY, Leo YS, Lye DC, Lin RT, Maurer-Stroh S, Lee B, Wang CI, Renia L, Ng LF. Human neutralising antibodies elicited by SARS-CoV-2 non-D614G variants offer cross-protection against the SARS-CoV-2 D614G variant. Clin Transl Immunology. 2021; 10(2):e1241. PMID: 33628442.
      Citations: 9     
    12. Windpessl M, Bruchfeld A, Anders HJ, Kramer H, Waldman M, Renia L, Ng LFP, Xing Z, Kronbichler A. COVID-19 vaccines and kidney disease. Nat Rev Nephrol. 2021 05; 17(5):291-293. PMID: 33558753.
      Citations: 19     Fields:    Translation:HumansPHPublic Health
    13. Goh YS, Chavatte JM, Lim Jieling A, Lee B, Hor PX, Amrun SN, Lee CY, Chee RS, Wang B, Lee CY, Ngoh EZX, Wang CI, Young BE, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Chen MI, Leo YS, Lye DC, Ng LFP, Lin RTP, Renia L. Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19. Cell Rep Med. 2021 02 16; 2(2):100193. PMID: 33495757.
      Citations: 10     
    14. Perico L, Benigni A, Casiraghi F, Ng LFP, Renia L, Remuzzi G. Immunity, endothelial injury and complement-induced coagulopathy in COVID-19. Nat Rev Nephrol. 2021 01; 17(1):46-64. PMID: 33077917.
      Citations: 105     Fields:    Translation:Humans
    15. Carissimo G, Xu W, Kwok I, Abdad MY, Chan YH, Fong SW, Puan KJ, Lee CY, Yeo NK, Amrun SN, Chee RS, How W, Chan S, Fan BE, Andiappan AK, Lee B, Rötzschke O, Young BE, Leo YS, Lye DC, Renia L, Ng LG, Larbi A, Ng LF. Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19. Nat Commun. 2020 10 16; 11(1):5243. PMID: 33067472.
      Citations: 35     Fields:    Translation:HumansCellsPHPublic Health
    16. Moore SC, Penrice-Randal R, Alruwaili M, Randle N, Armstrong S, Hartley C, Haldenby S, Dong X, Alrezaihi A, Almsaud M, Bentley E, Clark J, García-Dorival I, Gilmore P, Han X, Jones B, Luu L, Sharma P, Shawli G, Sun Y, Zhao Q, Pullan ST, Carter DP, Bewley K, Dunning J, Zhou EM, Solomon T, Beadsworth M, Cruise J, Crook DW, Matthews DA, Davidson AD, Mahmood Z, Aljabr W, Druce J, Vipond R, Ng L, Renia L, Openshaw PJM, Baillie JK, Carroll MW, Stewart J, Darby A, Semple M, Turtle L, Hiscox JA. Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism. Viruses. 2020 10 14; 12(10). PMID: 33066701.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    17. Ng DHL, Choy CY, Chan YH, Young BE, Fong SW, Ng LFP, Renia L, Lye DC, Chia PY. Fever Patterns, Cytokine Profiles, and Outcomes in COVID-19. Open Forum Infect Dis. 2020 Sep; 7(9):ofaa375. PMID: 32999893.
      Citations: 8     
    18. Kam YW, Ahmed MY, Amrun SN, Lee B, Refaie T, Elgizouli K, Fong SW, Renia L, Ng LF. Systematic analysis of disease-specific immunological signatures in patients with febrile illness from Saudi Arabia. Clin Transl Immunology. 2020; 9(8):e1163. PMID: 32864128.
      Citations: 5     
    19. Young BE, Fong SW, Chan YH, Mak TM, Ang LW, Anderson DE, Lee CY, Amrun SN, Lee B, Goh YS, Su YCF, Wei WE, Kalimuddin S, Chai LYA, Pada S, Tan SY, Sun L, Parthasarathy P, Chen YYC, Barkham T, Lin RTP, Maurer-Stroh S, Leo YS, Wang LF, Renia L, Lee VJ, Smith GJD, Lye DC, Ng LFP. Effects of a major deletion in the SARS-CoV-2 genome on the severity of infection and the inflammatory response: an observational cohort study. Lancet. 2020 08 29; 396(10251):603-611. PMID: 32822564.
      Citations: 129     Fields:    Translation:HumansCellsPHPublic Health
    20. Lee PH, Tay WC, Sutjipto S, Fong SW, Ong SWX, Wei WE, Chan YH, Ling LM, Young BE, Toh MPH, Renia L, Ng LF, Leo YS, Lye DC, Lee TH. Associations of viral ribonucleic acid (RNA) shedding patterns with clinical illness and immune responses in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection. Clin Transl Immunology. 2020; 9(7):e1160. PMID: 32742654.
      Citations: 12     
    21. Ong SWX, Tan WYT, Chan YH, Fong SW, Renia L, Ng LF, Leo YS, Lye DC, Young BE. Safety and potential efficacy of cyclooxygenase-2 inhibitors in coronavirus disease 2019. Clin Transl Immunology. 2020; 9(7):e1159. PMID: 32728438.
      Citations: 5     
    22. Amrun SN, Lee CY, Lee B, Fong SW, Young BE, Chee RS, Yeo NK, Torres-Ruesta A, Carissimo G, Poh CM, Chang ZW, Tay MZ, Chan YH, Chen MI, Low JG, Tambyah PA, Kalimuddin S, Pada S, Tan SY, Sun LJ, Leo YS, Lye DC, Renia L, Ng LFP. Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity. EBioMedicine. 2020 Aug; 58:102911. PMID: 32711254.
      Citations: 35     Fields:    Translation:HumansCellsPHPublic Health
    23. Poh CM, Carissimo G, Wang B, Amrun SN, Lee CY, Chee RS, Fong SW, Yeo NK, Lee WH, Torres-Ruesta A, Leo YS, Chen MI, Tan SY, Chai LYA, Kalimuddin S, Kheng SSG, Thien SY, Young BE, Lye DC, Hanson BJ, Wang CI, Renia L, Ng LFP. Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients. Nat Commun. 2020 06 01; 11(1):2806. PMID: 32483236.
      Citations: 118     Fields:    Translation:HumansCellsPHPublic Health
    24. Tay MZ, Poh CM, Rénia L, MacAry PA, Ng LFP. The trinity of COVID-19: immunity, inflammation and intervention. Nat Rev Immunol. 2020 06; 20(6):363-374. PMID: 32346093.
      Citations: 1201     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    25. Lee CY, Lin RTP, Renia L, Ng LFP. Serological Approaches for COVID-19: Epidemiologic Perspective on Surveillance and Control. Front Immunol. 2020; 11:879. PMID: 32391022.
      Citations: 96     Fields:    Translation:HumansCellsPHPublic Health
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