"Perilipin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A perilipin that is expressed by many different cell types. It binds FATTY ACIDS and CHOLESTEROL, stabilizes TRIGLYCERIDES, and localizes to both the surface and hydrophobic core of LIPID DROPLETS, as well as the ENDOPLASMIC RECTICULUM and PLASMA MEMBRANE in MACROPHAGES. It also plays a central role in the biogenesis of lipid droplets and FOAM CELLS and is highly expressed by macrophages at atherosclerotic lesions in human arteries along with the INFLAMMATION markers TNF-ALPHA; MCP-1 RECEPTOR; and IL-6.
| Descriptor ID |
D000070780
|
| MeSH Number(s) |
D12.776.157.464.500.750
|
| Concept/Terms |
Perilipin-2- Perilipin-2
- Perilipin 2
- ADRP Protein
- Adipose Differentiation-Related Protein
- Adipose Differentiation Related Protein
- Protein, Adipose Differentiation-Related
- PLIN2 Protein
- Protein, PLIN2
- Perilipin 2 Protein
- Protein, Perilipin 2
- Adipophilin
|
Below are MeSH descriptors whose meaning is more general than "Perilipin-2".
Below are MeSH descriptors whose meaning is more specific than "Perilipin-2".
This graph shows the total number of publications written about "Perilipin-2" by people in this website by year, and whether "Perilipin-2" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 7 | 7 |
| 2005 | 0 | 8 | 8 |
| 2006 | 0 | 8 | 8 |
| 2007 | 0 | 10 | 10 |
| 2008 | 0 | 13 | 13 |
| 2009 | 0 | 13 | 13 |
| 2010 | 0 | 12 | 12 |
| 2011 | 0 | 9 | 9 |
| 2012 | 0 | 13 | 13 |
| 2013 | 0 | 19 | 19 |
| 2014 | 0 | 10 | 10 |
| 2015 | 1 | 11 | 12 |
| 2016 | 7 | 8 | 15 |
| 2017 | 8 | 5 | 13 |
| 2018 | 7 | 7 | 14 |
| 2019 | 2 | 1 | 3 |
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Below are the most recent publications written about "Perilipin-2" by people in Profiles.
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PLIN2 Functions As a Novel Link Between Progesterone Signaling and Metabolism in Uterine Leiomyoma Cells. J Clin Endocrinol Metab. 2019 12 01; 104(12):6256-6264.
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SAR1B GTPase is necessary to protect intestinal cells from disorders of lipid homeostasis, oxidative stress, and inflammation. J Lipid Res. 2019 10; 60(10):1755-1764.
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Adipophilin expression is an indicator of poor prognosis in patients with pancreatic ductal adenocarcinoma: An immunohistochemical analysis. Pancreatology. 2019 Apr; 19(3):443-448.
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Influence of Recipient Site on the Function and Survival of Fat Grafts. Ann Plast Surg. 2019 01; 82(1):110-115.
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PLIN2 Is Essential for Trophoblastic Lipid Droplet Accumulation and Cell Survival During Hypoxia. Endocrinology. 2018 12 01; 159(12):3937-3949.
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Urinary aquaporin 1 and perilipin 2: Can these novel markers accurately characterize small renal masses and help guide patient management? Int J Urol. 2019 02; 26(2):260-265.
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Ectopic lipid accumulation: potential role in tubular injury and inflammation in diabetic kidney disease. Clin Sci (Lond). 2018 11 30; 132(22):2407-2422.
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Muscle-specific Perilipin2 down-regulation affects lipid metabolism and induces myofiber hypertrophy. J Cachexia Sarcopenia Muscle. 2019 02; 10(1):95-110.
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Super-resolution microscopy localizes perilipin 5 at lipid droplet-mitochondria interaction sites and at lipid droplets juxtaposing to perilipin 2. Biochim Biophys Acta Mol Cell Biol Lipids. 2018 11; 1863(11):1423-1432.
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Ethanol and C2 ceramide activate fatty acid oxidation in human hepatoma cells. Sci Rep. 2018 08 27; 8(1):12923.