"Cortisone Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the interconversion of a ketone and hydroxy group at C-20 of cortisone and other 17,20,21-trihydroxy steroids. EC 1.1.1.53.
| Descriptor ID |
D003349
|
| MeSH Number(s) |
D08.811.682.047.820.125.150
|
| Concept/Terms |
Cortisone Reductase- Cortisone Reductase
- Reductase, Cortisone
- 20-beta-Hydroxysteroid Dehydrogenase
- 20 beta Hydroxysteroid Dehydrogenase
- Dehydrogenase, 20-beta-Hydroxysteroid
|
Below are MeSH descriptors whose meaning is more general than "Cortisone Reductase".
Below are MeSH descriptors whose meaning is more specific than "Cortisone Reductase".
This graph shows the total number of publications written about "Cortisone Reductase" by people in this website by year, and whether "Cortisone Reductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cortisone Reductase" by people in Profiles.
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Steroid biomarkers and genetic studies reveal inactivating mutations in hexose-6-phosphate dehydrogenase in patients with cortisone reductase deficiency. J Clin Endocrinol Metab. 2008 Oct; 93(10):3827-32.
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Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia. J Clin Endocrinol Metab. 2007 Jan; 92(1):359-62.
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11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response. Endocr Rev. 2004 Oct; 25(5):831-66.
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Mutations in the genes encoding 11beta-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency. Nat Genet. 2003 Aug; 34(4):434-9.