"Immunoglobulins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.
| Descriptor ID |
D007136
|
| MeSH Number(s) |
D12.776.124.486.485 D12.776.124.790.651 D12.776.377.715.548
|
| Concept/Terms |
Immunoglobulins- Immunoglobulins
- Immunoglobulin
- Globulins, Immune
- Immune Globulins
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulins".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulins".
This graph shows the total number of publications written about "Immunoglobulins" by people in this website by year, and whether "Immunoglobulins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 32 | 33 | 65 |
| 1992 | 20 | 32 | 52 |
| 1993 | 24 | 29 | 53 |
| 1994 | 17 | 25 | 42 |
| 1995 | 25 | 26 | 51 |
| 1996 | 22 | 15 | 37 |
| 1997 | 18 | 25 | 43 |
| 1998 | 22 | 30 | 52 |
| 1999 | 16 | 29 | 45 |
| 2000 | 17 | 25 | 42 |
| 2001 | 29 | 22 | 51 |
| 2002 | 84 | 109 | 193 |
| 2003 | 74 | 106 | 180 |
| 2004 | 79 | 131 | 210 |
| 2005 | 80 | 136 | 216 |
| 2006 | 82 | 112 | 194 |
| 2007 | 102 | 137 | 239 |
| 2008 | 83 | 134 | 217 |
| 2009 | 90 | 115 | 205 |
| 2010 | 94 | 116 | 210 |
| 2011 | 98 | 81 | 179 |
| 2012 | 86 | 114 | 200 |
| 2013 | 121 | 130 | 251 |
| 2014 | 103 | 115 | 218 |
| 2015 | 105 | 78 | 183 |
| 2016 | 100 | 104 | 204 |
| 2017 | 91 | 95 | 186 |
| 2018 | 90 | 87 | 177 |
| 2019 | 34 | 38 | 72 |
| 2020 | 8 | 20 | 28 |
To return to the timeline, click here.
Below are the most recent publications written about "Immunoglobulins" by people in Profiles.
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Significance of serology testing to assist timely diagnosis of SARS-CoV-2 infections: implication from a family cluster. Emerg Microbes Infect. 2020 Dec; 9(1):924-927.
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SARS-CoV-2 and Three Related Coronaviruses Utilize Multiple ACE2 Orthologs and Are Potently Blocked by an Improved ACE2-Ig. J Virol. 2020 10 27; 94(22).
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Before Virus, After Virus: A Reckoning. Cell. 2020 10 15; 183(2):308-314.
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Prevalence of asymptomatic SARS-CoV-2-positive individuals in the general population of northern Italy and evaluation of a diagnostic serological ELISA test: a cross-sectional study protocol. BMJ Open. 2020 10 06; 10(10):e040036.
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Distinguishable Immunologic Characteristics of COVID-19 Patients with Comorbid Type 2 Diabetes Compared with Nondiabetic Individuals. Mediators Inflamm. 2020; 2020:6914878.
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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans. Science. 2020 09 04; 369(6508):1210-1220.
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Ribavirin therapy for severe COVID-19: a retrospective cohort study. Int J Antimicrob Agents. 2020 Sep; 56(3):106114.
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Acute Inflammation and Elevated Cardiac Markers in a Two-Month-Old Infant with Severe Acute Respiratory Syndrome Coronavirus 2 Infection Presenting with Cardiac Symptoms. Pediatr Infect Dis J. 2020 07; 39(7):e149-e151.
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Passive Immunity for Coronavirus Disease 2019: A Commentary on Therapeutic Aspects Including Convalescent Plasma. Semin Thromb Hemost. 2020 Oct; 46(7):796-803.
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Clinically suspected myocarditis in the course of coronavirus infection. Eur Heart J. 2020 06 07; 41(22):2118-2119.