"Immunoglobulins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Multi-subunit proteins which function in IMMUNITY. They are produced by B LYMPHOCYTES from the IMMUNOGLOBULIN GENES. They are comprised of two heavy (IMMUNOGLOBULIN HEAVY CHAINS) and two light chains (IMMUNOGLOBULIN LIGHT CHAINS) with additional ancillary polypeptide chains depending on their isoforms. The variety of isoforms include monomeric or polymeric forms, and transmembrane forms (B-CELL ANTIGEN RECEPTORS) or secreted forms (ANTIBODIES). They are divided by the amino acid sequence of their heavy chains into five classes (IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M) and various subclasses.
| Descriptor ID |
D007136
|
| MeSH Number(s) |
D12.776.124.486.485 D12.776.124.790.651 D12.776.377.715.548
|
| Concept/Terms |
Immunoglobulins- Immunoglobulins
- Immunoglobulin
- Globulins, Immune
- Immune Globulins
|
Below are MeSH descriptors whose meaning is more general than "Immunoglobulins".
Below are MeSH descriptors whose meaning is more specific than "Immunoglobulins".
This graph shows the total number of publications written about "Immunoglobulins" by people in this website by year, and whether "Immunoglobulins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 9 | 12 | 21 |
| 1992 | 9 | 13 | 22 |
| 1993 | 8 | 18 | 26 |
| 1994 | 6 | 8 | 14 |
| 1995 | 9 | 16 | 25 |
| 1996 | 3 | 7 | 10 |
| 1997 | 4 | 9 | 13 |
| 1998 | 7 | 14 | 21 |
| 1999 | 8 | 16 | 24 |
| 2000 | 5 | 9 | 14 |
| 2001 | 14 | 12 | 26 |
| 2002 | 41 | 62 | 103 |
| 2003 | 40 | 66 | 106 |
| 2004 | 42 | 73 | 115 |
| 2005 | 53 | 90 | 143 |
| 2006 | 56 | 57 | 113 |
| 2007 | 66 | 86 | 152 |
| 2008 | 53 | 96 | 149 |
| 2009 | 58 | 75 | 133 |
| 2010 | 54 | 76 | 130 |
| 2011 | 59 | 49 | 108 |
| 2012 | 54 | 65 | 119 |
| 2013 | 74 | 85 | 159 |
| 2014 | 65 | 75 | 140 |
| 2015 | 67 | 54 | 121 |
| 2016 | 67 | 69 | 136 |
| 2017 | 54 | 56 | 110 |
| 2018 | 65 | 61 | 126 |
| 2019 | 27 | 27 | 54 |
| 2020 | 16 | 28 | 44 |
| 2021 | 7 | 12 | 19 |
To return to the timeline, click here.
Below are the most recent publications written about "Immunoglobulins" by people in Profiles.
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High-dose intravenous immunoglobulins might modulate inflammation in COVID-19 patients. Life Sci Alliance. 2021 09; 4(9).
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Audio Interview: Monoclonal Antibodies and Vaccine Boosts. N Engl J Med. 2021 07 15; 385(3):e18.
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A serum proteome signature to predict mortality in severe COVID-19 patients. Life Sci Alliance. 2021 09; 4(9).
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Multi-system inflammatory syndrome in children during the coronavirus disease 2019 in Saudi Arabia: Clinical perspective from a case series. Medicine (Baltimore). 2021 Jun 04; 100(22):e25919.
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Avian antibodies (IgY) targeting spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) inhibit receptor binding and viral replication. PLoS One. 2021; 16(5):e0252399.
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The preparation of N-IgY targeting SARS-CoV-2 and its immunomodulation to IFN-? production in vitro. Int Immunopharmacol. 2021 Jul; 96:107797.
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Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2. Cell Rep. 2021 05 11; 35(6):109109.
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Integrative overview of antibodies against SARS-CoV-2 and their possible applications in COVID-19 prophylaxis and treatment. Microb Cell Fact. 2021 Apr 22; 20(1):88.
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Chicken IgY Antibodies Provide Mucosal Barrier against SARS-CoV-2 Virus and Other Pathogens. Isr Med Assoc J. 2021 Apr; 23(4):208-211.
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Antibody Therapy: From Diphtheria to Cancer, COVID-19, and Beyond. Monoclon Antib Immunodiagn Immunother. 2021 Apr; 40(2):36-49.