"Psychosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An intermediate in the biosynthesis of cerebrosides. It is formed by reaction of sphingosine with UDP-galactose and then itself reacts with fatty acid-Coenzyme A to form the cerebroside.
| Descriptor ID |
D011609
|
| MeSH Number(s) |
D02.033.100.700.700 D02.092.063.700.700 D09.400.410.420.806 D10.390.470.806 D10.570.877.360.806
|
| Concept/Terms |
Psychosine- Psychosine
- Sphingosine Galactoside
- Galactoside, Sphingosine
- Galactosylsphingosine
|
Below are MeSH descriptors whose meaning is more general than "Psychosine".
Below are MeSH descriptors whose meaning is more specific than "Psychosine".
This graph shows the total number of publications written about "Psychosine" by people in this website by year, and whether "Psychosine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 2 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 2 | 3 |
| 2007 | 1 | 0 | 1 |
| 2010 | 2 | 2 | 4 |
| 2011 | 2 | 2 | 4 |
| 2012 | 2 | 2 | 4 |
| 2013 | 3 | 5 | 8 |
| 2014 | 2 | 3 | 5 |
| 2015 | 1 | 4 | 5 |
| 2016 | 1 | 4 | 5 |
| 2017 | 1 | 1 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Psychosine" by people in Profiles.
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Ophthalmic manifestations of Gaucher disease: the most common lysosomal storage disorder. Br J Ophthalmol. 2019 03; 103(3):315-326.
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a-Synuclein interacts directly but reversibly with psychosine: implications for a-synucleinopathies. Sci Rep. 2018 08 20; 8(1):12462.
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Glucosylsphingosine is a reliable response biomarker in Gaucher disease. Am J Hematol. 2018 06; 93(6):E140-E142.
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Glucocerebrosidase haploinsufficiency in A53T a-synuclein mice impacts disease onset and course. Mol Genet Metab. 2017 12; 122(4):198-208.
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Glucosylsphingosine Causes Hematological and Visceral Changes in Mice-Evidence for a Pathophysiological Role in Gaucher Disease. Int J Mol Sci. 2017 Oct 20; 18(10).
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Patient fibroblasts-derived induced neurons demonstrate autonomous neuronal defects in adult-onset Krabbe disease. Oncotarget. 2016 11 15; 7(46):74496-74509.
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Glycosynthase mediated synthesis of psychosine. Carbohydr Res. 2016 Nov 29; 435:97-99.
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Progression of Behavioral and CNS Deficits in a Viable Murine Model of Chronic Neuronopathic Gaucher Disease. PLoS One. 2016; 11(9):e0162367.
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Generation of a LacZ reporter transgenic mouse line for the stereological analysis of oligodendrocyte loss in galactosylceramidase deficiency. J Neurosci Res. 2016 12; 94(12):1520-1530.
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A peptide-linked recombinant glucocerebrosidase for targeted neuronal delivery: Design, production, and assessment. J Biotechnol. 2016 Mar 10; 221:1-12.