"Theobromine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
3,7-Dimethylxanthine. The principle alkaloid in Theobroma cacao (the cacao bean) and other plants. A xanthine alkaloid that is used as a bronchodilator and as a vasodilator. It has a weaker diuretic activity than THEOPHYLLINE and is also a less powerful stimulant of smooth muscle. It has practically no stimulant effect on the central nervous system. It was formerly used as a diuretic and in the treatment of angina pectoris and hypertension. (From Martindale, The Extra Pharmacopoeia, 30th ed, pp1318-9)
| Descriptor ID |
D013805
|
| MeSH Number(s) |
D03.132.960.651 D03.633.100.759.758.824.651
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Theobromine".
Below are MeSH descriptors whose meaning is more specific than "Theobromine".
This graph shows the total number of publications written about "Theobromine" by people in this website by year, and whether "Theobromine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 1993 | 0 | 1 | 1 |
| 1995 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 0 | 2 |
| 2002 | 3 | 0 | 3 |
| 2003 | 0 | 1 | 1 |
| 2004 | 3 | 2 | 5 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 3 | 4 |
| 2007 | 2 | 4 | 6 |
| 2008 | 0 | 3 | 3 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 4 | 4 |
| 2012 | 1 | 3 | 4 |
| 2013 | 2 | 6 | 8 |
| 2014 | 3 | 3 | 6 |
| 2015 | 4 | 4 | 8 |
| 2016 | 3 | 4 | 7 |
| 2017 | 1 | 2 | 3 |
| 2018 | 3 | 3 | 6 |
| 2019 | 2 | 1 | 3 |
To return to the timeline, click here.
Below are the most recent publications written about "Theobromine" by people in Profiles.
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Cytotoxic and multidrug resistance reversal activity of phenothiazine derivative is strongly enhanced by theobromine, a phytochemical from cocoa. Eur J Pharmacol. 2019 Apr 15; 849:124-134.
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Genomic focus brings tea research to the boil. Nature. 2019 02; 566(7742):S12-S13.
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Exploring cocoa properties: is theobromine a cognitive modulator? Psychopharmacology (Berl). 2019 Feb; 236(2):561-572.
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Hongyacha, a Naturally Caffeine-Free Tea Plant from Fujian, China. J Agric Food Chem. 2018 Oct 31; 66(43):11311-11319.
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Effect of Consumption of Cocoa-Derived Products on Uric Acid Crystallization in Urine of Healthy Volunteers. Nutrients. 2018 Oct 16; 10(10).
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Antidepressant-Like Activity of Typical Antidepressant Drugs in the Forced Swim Test and Tail Suspension Test in Mice Is Augmented by DMPX, an Adenosine A2A Receptor Antagonist. Neurotox Res. 2019 Feb; 35(2):344-352.
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Sustainable Eco-Friendly Ultra-High-Performance Liquid Chromatographic Method for Simultaneous Determination of Caffeine and Theobromine in Commercial Teas: Evaluation of Greenness Profile Using NEMI and Eco-Scale Assessment Tools. J AOAC Int. 2018 Nov 01; 101(6):1781-1787.
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Changes in endothelial function, arterial stiffness and blood pressure in pregnant women after consumption of high-flavanol and high-theobromine chocolate: a double blind randomized clinical trial. Hypertens Pregnancy. 2018 May; 37(2):68-80.
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Different behavior of polyphenols in energy metabolism of lipopolysaccharide-stimulated cells. Food Res Int. 2019 04; 118:96-100.
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Isolation and characterisation of theobromine-degrading filamentous fungi. Microbiol Res. 2018 Jan; 206:16-24.