"Theophylline" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A methyl xanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Theophylline inhibits the 3',5'-CYCLIC NUCLEOTIDE PHOSPHODIESTERASE that degrades CYCLIC AMP thus potentiates the actions of agents that act through ADENYLYL CYCLASES and cyclic AMP.
| Descriptor ID |
D013806
|
| MeSH Number(s) |
D03.132.960.751 D03.633.100.759.758.824.751
|
| Concept/Terms |
Theophylline- Theophylline
- 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione
- 1,3-Dimethylxanthine
- 1,3 Dimethylxanthine
|
Below are MeSH descriptors whose meaning is more general than "Theophylline".
Below are MeSH descriptors whose meaning is more specific than "Theophylline".
This graph shows the total number of publications written about "Theophylline" by people in this website by year, and whether "Theophylline" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 7 | 6 | 13 |
| 1992 | 9 | 12 | 21 |
| 1993 | 15 | 4 | 19 |
| 1994 | 2 | 7 | 9 |
| 1995 | 6 | 4 | 10 |
| 1996 | 6 | 5 | 11 |
| 1997 | 8 | 5 | 13 |
| 1998 | 5 | 3 | 8 |
| 1999 | 3 | 7 | 10 |
| 2000 | 9 | 6 | 15 |
| 2001 | 6 | 5 | 11 |
| 2002 | 24 | 10 | 34 |
| 2003 | 19 | 12 | 31 |
| 2004 | 25 | 15 | 40 |
| 2005 | 30 | 19 | 49 |
| 2006 | 27 | 19 | 46 |
| 2007 | 4 | 12 | 16 |
| 2008 | 14 | 24 | 38 |
| 2009 | 12 | 15 | 27 |
| 2010 | 12 | 13 | 25 |
| 2011 | 10 | 19 | 29 |
| 2012 | 15 | 17 | 32 |
| 2013 | 5 | 12 | 17 |
| 2014 | 9 | 22 | 31 |
| 2015 | 9 | 13 | 22 |
| 2016 | 20 | 8 | 28 |
| 2017 | 18 | 12 | 30 |
| 2018 | 18 | 7 | 25 |
| 2019 | 5 | 3 | 8 |
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Below are the most recent publications written about "Theophylline" by people in Profiles.
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Inhibition of Rat CYP1A2 and CYP2C11 by Honokiol, a Component of Traditional Chinese Medicine. Eur J Drug Metab Pharmacokinet. 2019 Dec; 44(6):787-796.
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Design, synthesis and biological evaluation of theophylline containing variant acetylene derivatives as a-amylase inhibitors. Bioorg Chem. 2019 11; 92:103120.
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Theophylline induces differentiation and modulates cytoskeleton dynamics and cytokines secretion in human melanoma-initiating cells. Life Sci. 2019 Aug 01; 230:121-131.
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Simultaneously Improving the Physicochemical Properties, Dissolution Performance, and Bioavailability of Apigenin and Daidzein by Co-Crystallization With Theophylline. J Pharm Sci. 2019 09; 108(9):2982-2993.
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Granisetron reduces the need for uterotonics but not sympathomimetics during cesarean delivery. Int J Gynaecol Obstet. 2019 Jun; 145(3):361-366.
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Design of Inhalable Solid Dosage Forms of Budesonide and Theophylline for Pulmonary Combination Therapy. AAPS PharmSciTech. 2019 Mar 07; 20(3):137.
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Reliability of the Hansen solubility parameters as co-crystal formation prediction tool. Int J Pharm. 2019 Mar 10; 558:319-327.
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Effects of theophylline therapy on respiratory muscle strength in patients with prolonged mechanical ventilation: A retrospective cohort study. Medicine (Baltimore). 2019 Jan; 98(2):e13982.
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A systematic review of phenytoin intoxication induced by compound phenytoin sodium, ephedrine hydrochloride and theophylline tablets in China. Medicine (Baltimore). 2018 Dec; 97(51):e13689.
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Theophylline inhibits cigarette smoke-induced inflammation in skeletal muscle by upregulating HDAC2 expression and decreasing NF-?B activation. . 2019 01 01; 316(1):L197-L205.