"Peptidyl-Dipeptidase A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A peptidyl-dipeptidase that catalyzes the release of a C-terminal dipeptide, -Xaa-*-Xbb-Xcc, when neither Xaa nor Xbb is Pro. It is a Cl(-)-dependent, zinc glycoprotein that is generally membrane-bound and active at neutral pH. It may also have endopeptidase activity on some substrates. (From Enzyme Nomenclature, 1992)
| Descriptor ID |
D007703
|
| MeSH Number(s) |
D08.811.277.656.350.350.687
|
| Concept/Terms |
Peptidyl-Dipeptidase A- Peptidyl-Dipeptidase A
- Peptidyl Dipeptidase A
- Angiotensin I-Converting Enzyme
- Angiotensin I Converting Enzyme
- Carboxycathepsin
- CD143 Antigens
- Kininase II
- Dipeptidyl Peptidase A
- Antigens, CD143
- Angiotensin Converting Enzyme
- Kininase A
|
Below are MeSH descriptors whose meaning is more general than "Peptidyl-Dipeptidase A".
Below are MeSH descriptors whose meaning is more specific than "Peptidyl-Dipeptidase A".
This graph shows the total number of publications written about "Peptidyl-Dipeptidase A" by people in this website by year, and whether "Peptidyl-Dipeptidase A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 10 | 4 | 14 |
| 1992 | 10 | 3 | 13 |
| 1993 | 6 | 8 | 14 |
| 1994 | 13 | 13 | 26 |
| 1995 | 9 | 11 | 20 |
| 1996 | 12 | 9 | 21 |
| 1997 | 18 | 10 | 28 |
| 1998 | 26 | 12 | 38 |
| 1999 | 24 | 16 | 40 |
| 2000 | 23 | 13 | 36 |
| 2001 | 18 | 14 | 32 |
| 2002 | 94 | 58 | 152 |
| 2003 | 97 | 59 | 156 |
| 2004 | 118 | 79 | 197 |
| 2005 | 91 | 81 | 172 |
| 2006 | 128 | 65 | 193 |
| 2007 | 121 | 56 | 177 |
| 2008 | 147 | 57 | 204 |
| 2009 | 106 | 61 | 167 |
| 2010 | 146 | 54 | 200 |
| 2011 | 134 | 61 | 195 |
| 2012 | 121 | 61 | 182 |
| 2013 | 159 | 74 | 233 |
| 2014 | 136 | 60 | 196 |
| 2015 | 94 | 52 | 146 |
| 2016 | 107 | 38 | 145 |
| 2017 | 81 | 54 | 135 |
| 2018 | 89 | 50 | 139 |
| 2019 | 23 | 22 | 45 |
| 2020 | 512 | 667 | 1179 |
| 2021 | 9 | 20 | 29 |
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Below are the most recent publications written about "Peptidyl-Dipeptidase A" by people in Profiles.
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Renin-angiotensin-aldosterone system peptide profiles in patients with COVID-19. Eur J Endocrinol. 2021 Apr; 184(4):543-552.
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Commentary for "Endocrine significance of SARS-CoV-2's Reliance on ACE2". Endocrinology. 2021 04 01; 162(4).
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Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry. PLoS Pathog. 2021 03; 17(3):e1009392.
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Functional and genetic analysis of viral receptor ACE2 orthologs reveals a broad potential host range of SARS-CoV-2. Proc Natl Acad Sci U S A. 2021 03 23; 118(12).
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Vitamin D supplementation in diabetic retinopathy in the era of COVID-19. Indian J Ophthalmol. 2021 03; 69(3):483-484.
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ACE/ACE2 balance might be instrumental to explain the certain comorbidities leading to severe COVID-19 cases. Biosci Rep. 2021 02 26; 41(2).
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ACE2 and energy metabolism: the connection between COVID-19 and chronic metabolic disorders. Clin Sci (Lond). 2021 02 12; 135(3):535-554.
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Mechanisms of COVID-19 Entry into the Cell: Potential Therapeutic Approaches Based on Virus Entry Inhibition in COVID-19 Patients with Underlying Diseases. Iran J Allergy Asthma Immunol. 2021 Feb 11; 20(1):11-23.
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Bow to the enemy: How flexibility of host protein receptors can favor SARS-CoV-2. Biophys J. 2021 03 16; 120(6):977-979.
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ACE2, TMPRSS2, and Furin expression in the nose and olfactory bulb in mice and humans. Rhinology. 2021 Feb 01; 59(1):105-109.