"Aminooxyacetic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A compound that inhibits aminobutyrate aminotransferase activity in vivo, thereby raising the level of gamma-aminobutyric acid in tissues.
| Descriptor ID |
D000625
|
| MeSH Number(s) |
D02.092.570.050 D02.241.081.018.207
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Aminooxyacetic Acid".
Below are MeSH descriptors whose meaning is more specific than "Aminooxyacetic Acid".
This graph shows the total number of publications written about "Aminooxyacetic Acid" by people in this website by year, and whether "Aminooxyacetic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 0 | 1 | 1 |
| 1994 | 1 | 1 | 2 |
| 1996 | 0 | 1 | 1 |
| 1999 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2017 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Aminooxyacetic Acid" by people in Profiles.
-
Impact of Pharmacological Inhibition of Hydrogen Sulphide Production in the SOD1G93A-ALS Mouse Model. Int J Mol Sci. 2019 May 24; 20(10).
-
Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells. Biochem Pharmacol. 2018 03; 149:174-185.
-
Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism. Nature. 2017 08 10; 548(7666):228-233.
-
High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate. Protein Sci. 2017 04; 26(4):727-736.
-
Both the H2S biosynthesis inhibitor aminooxyacetic acid and the mitochondrially targeted H2S donor AP39 exert protective effects in a mouse model of burn injury. Pharmacol Res. 2016 11; 113(Pt A):348-355.
-
Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancer. Nat Commun. 2016 06 20; 7:11971.
-
Carnosine and anserine homeostasis in skeletal muscle and heart is controlled by ß-alanine transamination. J Physiol. 2016 09 01; 594(17):4849-63.
-
Malate-Aspartate Shuttle Inhibitor Aminooxyacetate Acid Induces Apoptosis and Impairs Energy Metabolism of Both Resting Microglia and LPS-Activated Microglia. Neurochem Res. 2015 Jun; 40(6):1311-8.
-
The therapeutic potential of cystathionine ß-synthetase/hydrogen sulfide inhibition in cancer. Antioxid Redox Signal. 2015 Feb 10; 22(5):424-48.
-
Metabolomic profiling reveals a role for caspase-2 in lipoapoptosis. J Biol Chem. 2013 May 17; 288(20):14463-14475.