"Carisoprodol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A centrally acting skeletal muscle relaxant whose mechanism of action is not completely understood but may be related to its sedative actions. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1202)
| Descriptor ID |
D002328
|
| MeSH Number(s) |
D02.241.081.251.165
|
| Concept/Terms |
Carisoprodol- Carisoprodol
- Isopropylmeprobamate
- Isomeprobamate
- Carisoprodate
- Isobamate
|
Below are MeSH descriptors whose meaning is more general than "Carisoprodol".
Below are MeSH descriptors whose meaning is more specific than "Carisoprodol".
This graph shows the total number of publications written about "Carisoprodol" by people in this website by year, and whether "Carisoprodol" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 3 | 0 | 3 |
| 2005 | 2 | 0 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2011 | 2 | 0 | 2 |
| 2012 | 3 | 0 | 3 |
| 2013 | 0 | 1 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carisoprodol" by people in Profiles.
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A Single Amino Acid Residue at Transmembrane Domain 4 of the a Subunit Influences Carisoprodol Direct Gating Efficacy at GABAA Receptors. J Pharmacol Exp Ther. 2017 09; 362(3):395-404.
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Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose. J Emerg Med. 2017 May; 52(5):680-683.
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Assessment of direct gating and allosteric modulatory effects of meprobamate in recombinant GABA(A) receptors. Eur J Pharmacol. 2016 Mar 15; 775:149-58.
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A prospective evaluation of psychotherapeutic and illicit drug use in patients presenting with chronic pain at the time of initial evaluation. Pain Physician. 2013 Jan; 16(1):E1-E13.
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Carisoprodol: an underrecognized drug of abuse in north India. Gen Hosp Psychiatry. 2013 Jan-Feb; 35(1):89-92.
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CYP2C19 genetics in fatal carisoprodol intoxications. Eur J Clin Pharmacol. 2012 Nov; 68(11):1561-5.
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Postmortem carisoprodol and meprobamate concentrations in blood and liver: lack of significant redistribution. J Anal Toxicol. 2012 Apr; 36(3):177-81.
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Characterizing the subjective and psychomotor effects of carisoprodol in healthy volunteers. Pharmacol Biochem Behav. 2011 Nov; 100(1):138-43.
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Subjective and psychomotor effects of carisoprodol in combination with oxycodone in healthy volunteers. Drug Alcohol Depend. 2012 Jan 01; 120(1-3):229-32.
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Carisoprodol withdrawal after internet purchase. Neurologist. 2010 Jul; 16(4):262-4.