"Nitric Oxide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
| Descriptor ID |
D009569
|
| MeSH Number(s) |
D01.339.387 D01.625.550.500 D01.625.700.500 D01.650.550.587.600
|
| Concept/Terms |
Nitric Oxide- Nitric Oxide
- Oxide, Nitric
- Nitrogen Monoxide
- Monoxide, Nitrogen
- Nitric Oxide, Endothelium-Derived
- Endothelium-Derived Nitric Oxide
- Nitric Oxide, Endothelium Derived
- Endogenous Nitrate Vasodilator
- Nitrate Vasodilator, Endogenous
- Vasodilator, Endogenous Nitrate
- Mononitrogen Monoxide
- Monoxide, Mononitrogen
|
Below are MeSH descriptors whose meaning is more general than "Nitric Oxide".
Below are MeSH descriptors whose meaning is more specific than "Nitric Oxide".
This graph shows the total number of publications written about "Nitric Oxide" by people in this website by year, and whether "Nitric Oxide" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 29 | 6 | 35 |
| 1992 | 28 | 9 | 37 |
| 1993 | 53 | 15 | 68 |
| 1994 | 87 | 35 | 122 |
| 1995 | 115 | 54 | 169 |
| 1996 | 115 | 33 | 148 |
| 1997 | 155 | 57 | 212 |
| 1998 | 158 | 62 | 220 |
| 1999 | 167 | 71 | 238 |
| 2000 | 170 | 75 | 245 |
| 2001 | 138 | 103 | 241 |
| 2002 | 654 | 461 | 1115 |
| 2003 | 647 | 478 | 1125 |
| 2004 | 622 | 523 | 1145 |
| 2005 | 649 | 589 | 1238 |
| 2006 | 592 | 570 | 1162 |
| 2007 | 586 | 615 | 1201 |
| 2008 | 587 | 661 | 1248 |
| 2009 | 536 | 652 | 1188 |
| 2010 | 538 | 704 | 1242 |
| 2011 | 606 | 733 | 1339 |
| 2012 | 516 | 814 | 1330 |
| 2013 | 554 | 793 | 1347 |
| 2014 | 526 | 778 | 1304 |
| 2015 | 466 | 702 | 1168 |
| 2016 | 437 | 735 | 1172 |
| 2017 | 423 | 778 | 1201 |
| 2018 | 373 | 619 | 992 |
| 2019 | 134 | 258 | 392 |
| 2020 | 33 | 19 | 52 |
| 2021 | 2 | 4 | 6 |
To return to the timeline, click here.
Below are the most recent publications written about "Nitric Oxide" by people in Profiles.
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Lung diffusing capacity for nitric oxide and carbon monoxide following mild-to-severe COVID-19. Physiol Rep. 2021 02; 9(4):e14748.
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Exploring the Pivotal Immunomodulatory and Anti-Inflammatory Potentials of Glycyrrhizic and Glycyrrhetinic Acids. Mediators Inflamm. 2021; 2021:6699560.
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Coronavirus Disease 2019 (COVID-19): Research, Clinical Knowledge, and Preventive Measures. J Environ Pathol Toxicol Oncol. 2021; 40(1):29-42.
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COVID-19 Is an Endothelial Disease: Implications of Nitric Oxide. Adv Exp Med Biol. 2021; 1321:109-113.
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Perspectives for the Use of N-acetylcysteine as a Candidate Drug to Treat COVID-19. Mini Rev Med Chem. 2021; 21(3):268-272.
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The role of NO in COVID-19 and potential therapeutic strategies. Free Radic Biol Med. 2021 02 01; 163:153-162.
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Tracing the path of inhaled nitric oxide: Biological consequences of protein nitrosylation. Pediatr Pulmonol. 2021 02; 56(2):525-538.
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Endothelial pulsatile shear stress is a backstop for COVID-19. Emerg Top Life Sci. 2020 12 11; 4(4):379-387.
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Nitric oxide's physiologic effects and potential as a therapeutic agent against COVID-19. J Breath Res. 2020 12 05; 15(1):014001.
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High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2020 12; 136(6):1109-1113.