"Gigantism" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The condition of accelerated and excessive GROWTH in children or adolescents who are exposed to excess HUMAN GROWTH HORMONE before the closure of EPIPHYSES. It is usually caused by somatotroph hyperplasia or a GROWTH HORMONE-SECRETING PITUITARY ADENOMA. These patients are of abnormally tall stature, more than 3 standard deviations above normal mean height for age.
| Descriptor ID |
D005877
|
| MeSH Number(s) |
C05.116.099.492 C05.116.132.479 C19.700.355.528
|
| Concept/Terms |
Gigantism- Gigantism
- Pituitary Gigantism
- Gigantism, Pituitary
|
Below are MeSH descriptors whose meaning is more general than "Gigantism".
Below are MeSH descriptors whose meaning is more specific than "Gigantism".
This graph shows the total number of publications written about "Gigantism" by people in this website by year, and whether "Gigantism" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 1 | 0 | 1 |
| 1992 | 1 | 0 | 1 |
| 1995 | 1 | 0 | 1 |
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 0 | 1 |
| 1999 | 4 | 0 | 4 |
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 1 | 3 |
| 2002 | 1 | 1 | 2 |
| 2003 | 3 | 0 | 3 |
| 2004 | 4 | 1 | 5 |
| 2005 | 2 | 0 | 2 |
| 2006 | 2 | 1 | 3 |
| 2007 | 4 | 2 | 6 |
| 2008 | 1 | 1 | 2 |
| 2009 | 3 | 0 | 3 |
| 2010 | 8 | 2 | 10 |
| 2011 | 4 | 2 | 6 |
| 2012 | 6 | 0 | 6 |
| 2013 | 10 | 1 | 11 |
| 2014 | 5 | 3 | 8 |
| 2015 | 11 | 3 | 14 |
| 2016 | 14 | 2 | 16 |
| 2017 | 5 | 1 | 6 |
| 2018 | 9 | 2 | 11 |
| 2019 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Gigantism" by people in Profiles.
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An Adolescent with Progressive Enlargement of Digits: Case report and proposed diagnostic criteria for macrodystrophia lipomatosa. Sultan Qaboos Univ Med J. 2018 Nov; 18(4):e553-e556.
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Tuberous Sclerosis Complex Associated with Hemihypertrophy and Combined Vascular Malformations. Actas Dermosifiliogr. 2019 Mar; 110(2):164-167.
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Further data corroborating a pituitary contribution to the genesis of the Cyclopean myth. Hormones (Athens). 2018 Dec; 17(4):595-596.
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Impact of X-ray Exposure on the Proliferation and Differentiation of Human Pre-Adipocytes. Int J Mol Sci. 2018 Sep 11; 19(9).
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For Debate: The Significance of Etiologic Diagnosis in Neonates with Overgrowth Syndromes. Lesson Learned from the Simpson-Golabi-Behmel Syndrome. Pediatr Endocrinol Rev. 2018 Sep; 16(1):171-177.
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Duplications of GPC3 and GPC4 genes in symptomatic female carriers of Simpson-Golabi-Behmel syndrome type 1. Eur J Med Genet. 2019 Apr; 62(4):243-247.
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Acute lymphoblastic leukemia in a male with Simpson-Golabi-Behmel syndrome. . 2018 07; 176(7):1680-1682.
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Ovotesticular Disorder of Sex Development (Ovotestis) in Simpson-Golabi-Behmel Syndrome: Expansion of the Clinical Spectrum. Pediatr Dev Pathol. 2019 Jan-Feb; 22(1):70-74.
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An orphan G-protein-coupled receptor causes human gigantism and/or acromegaly: Molecular biology and clinical correlations. Best Pract Res Clin Endocrinol Metab. 2018 04; 32(2):125-140.
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DEHP deregulates adipokine levels and impairs fatty acid storage in human SGBS-adipocytes. Sci Rep. 2018 02 22; 8(1):3447.