"Benzothiadiazines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Heterocyclic compounds of a ring with SULFUR and two NITROGEN atoms fused to a BENZENE ring. Members inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS and are used as DIURETICS.
| Descriptor ID |
D001581
|
| MeSH Number(s) |
D02.886.590.700.135 D02.886.655.500 D03.633.100.174
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Benzothiadiazines".
Below are MeSH descriptors whose meaning is more specific than "Benzothiadiazines".
This graph shows the total number of publications written about "Benzothiadiazines" by people in this website by year, and whether "Benzothiadiazines" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1992 | 1 | 0 | 1 |
| 1993 | 2 | 2 | 4 |
| 1994 | 2 | 1 | 3 |
| 1995 | 1 | 1 | 2 |
| 1996 | 3 | 1 | 4 |
| 1997 | 2 | 0 | 2 |
| 1999 | 1 | 0 | 1 |
| 2000 | 3 | 1 | 4 |
| 2001 | 4 | 1 | 5 |
| 2002 | 4 | 9 | 13 |
| 2003 | 17 | 12 | 29 |
| 2004 | 17 | 18 | 35 |
| 2005 | 9 | 8 | 17 |
| 2006 | 3 | 1 | 4 |
| 2007 | 3 | 2 | 5 |
| 2008 | 8 | 2 | 10 |
| 2009 | 10 | 2 | 12 |
| 2010 | 4 | 3 | 7 |
| 2011 | 8 | 5 | 13 |
| 2012 | 4 | 4 | 8 |
| 2013 | 5 | 2 | 7 |
| 2014 | 7 | 1 | 8 |
| 2015 | 4 | 4 | 8 |
| 2016 | 5 | 1 | 6 |
| 2017 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Benzothiadiazines" by people in Profiles.
-
Comparative Molecular Field Analysis and Molecular Docking Studies on Quinolinone Derivatives Indicate Potential Hepatitis C Virus Inhibitors. Cell Biochem Biophys. 2019 Jun; 77(2):139-156.
-
Proteome-Wide Analysis of Cysteine S-Sulfenylation Using a Benzothiazine-Based Probe. Curr Protoc Protein Sci. 2019 02; 95(1):e76.
-
Degeneration of cholinergic basal forebrain nuclei after focally evoked status epilepticus. Neurobiol Dis. 2019 01; 121:76-94.
-
Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds. J Med Chem. 2018 06 28; 61(12):5279-5291.
-
7-Phenoxy-Substituted 3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-Dioxides as Positive Allosteric Modulators of a-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors with Nanomolar Potency. J Med Chem. 2018 01 11; 61(1):251-264.
-
Unitary Properties of AMPA Receptors with Reduced Desensitization. Biophys J. 2017 Nov 21; 113(10):2218-2235.
-
Basagran® induces developmental malformations and changes the bacterial community of zebrafish embryos. Environ Pollut. 2017 Feb; 221:52-63.
-
Screening of hepatitis C NS5B polymerase inhibitors containing benzothiadiazine core: a steered molecular dynamics. J Biomol Struct Dyn. 2017 Jun; 35(8):1743-1757.
-
Enthalpy-Entropy Compensation in the Binding of Modulators at Ionotropic Glutamate Receptor GluA2. Biophys J. 2016 06 07; 110(11):2397-2406.
-
Synthesis of benzothiadiazine derivatives exhibiting dual activity as aldose reductase inhibitors and antioxidant agents. Bioorg Med Chem Lett. 2016 06 15; 26(12):2880-2885.