Apolipoprotein E2

"Apolipoprotein E2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.
MeSH information
One of three major isoforms of apolipoprotein E. In humans, Apo E2 differs from APOLIPOPROTEIN E3 at one residue 158 where arginine is replaced by cysteine (R158--C). In contrast to Apo E3, Apo E2 displays extremely low binding affinity for LDL receptors (RECEPTORS, LDL) which mediate the internalization and catabolism of lipoprotein particles in liver cells. ApoE2 allelic homozygosity is associated with HYPERLIPOPROTEINEMIA TYPE III.


Publications
This graph shows the total number of publications written about "Apolipoprotein E2" by people in this website by year, and whether "Apolipoprotein E2" was a major or minor topic of these publications.
Bar chart showing 222 publications over 22 distinct years, with a maximum of 21 publications in 2011
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