Kwok-Yung Yuen

Institutionthe University of Hong Kong
AddressHong Kong
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 82 Covid-19 publications, with a maximum of 11 publications in August 2020
    All Publications
    Bar chart showing 949 publications over 31 distinct years, with a maximum of 81 publications in 2020
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ye ZW, Yuan S, Chan JF, Zhang AJ, Yu CY, Ong CP, Yang D, Chan CC, Tang K, Cao J, Poon VK, Chan CC, Cai JP, Chu H, Yuen KY, Jin DY. Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection. Emerg Microbes Infect. 2021 Dec; 10(1):291-304. PMID: 33538646.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. To KK, Sridhar S, Chiu KH, Hung DL, Li X, Hung IF, Tam AR, Chung TW, Chan JF, Zhang AJ, Cheng VC, Yuen KY. Lessons learned 1 year after SARS-CoV-2 emergence leading to COVID-19 pandemic. Emerg Microbes Infect. 2021 Dec; 10(1):507-535. PMID: 33666147.
      Citations:    Fields:    
    3. Cheng VC, Wong SC, Tong DW, Chuang VW, Chen JH, Lee LL, To KK, Hung IF, Ho PL, Yeung DT, Chung KL, Yuen KY. Multi-pronged infection control strategy to achieve zero nosocomial COVID-19 infection among Hong Kong healthcare workers in the first 300 days of combat. Infect Control Hosp Epidemiol. 2021 Mar 19; 1-39. PMID: 33736729.
      Citations:    Fields:    
    4. Yuan S, Yin X, Meng X, Chan JF, Ye ZW, Riva L, Pache L, Chan CC, Lai PM, Chan CC, Poon VK, Lee AC, Matsunaga N, Pu Y, Yuen CK, Cao J, Liang R, Tang K, Sheng L, Du Y, Xu W, Lau CY, Sit KY, Au WK, Wang R, Zhang YY, Tang YD, Clausen TM, Pihl J, Oh J, Sze KH, Zhang AJ, Chu H, Kok KH, Wang D, Cai XH, Esko JD, Hung IF, Li RA, Chen H, Sun H, Jin DY, Sun R, Chanda SK, Yuen KY. Clofazimine broadly inhibits coronaviruses including SARS-CoV-2. Nature. 2021 Mar 16. PMID: 33727703.
      Citations:    Fields:    
    5. Zhao H, To KKW, Lam H, Zhou X, Chan JF, Peng Z, Lee ACY, Cai J, Chan WM, Ip JD, Chan CC, Yeung ML, Zhang AJ, Chu AWH, Jiang S, Yuen KY. Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2. Nat Commun. 2021 03 09; 12(1):1517. PMID: 33750821.
      Citations:    Fields:    
    6. Wong SC, Lai-Ha Yuen L, Hon-Kwan Chen J, Yuen KY, Chi-Chung Cheng V. Infection control challenges in handling recurrent blockage of sewage pipes in isolation facility designated for COVID-19 patients. J Hosp Infect. 2021 Mar 07. PMID: 33691161.
      Citations:    Fields:    
    7. Tse H, Lung DC, Wong SC, Ip KF, Wu TC, To KK, Kok KH, Yuen KY, Choi GK. Emergence of a Severe Acute Respiratory Syndrome Coronavirus 2 virus variant with novel genomic architecture in Hong Kong. Clin Infect Dis. 2021 Mar 02. PMID: 33675655.
      Citations:    Fields:    
    8. Yeung ML, Teng JLL, Jia L, Zhang C, Huang C, Cai JP, Zhou R, Chan KH, Zhao H, Zhu L, Siu KL, Fung SY, Yung S, Chan TM, To KK, Chan JF, Cai Z, Lau SKP, Chen Z, Jin DY, Woo PCY, Yuen KY. Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system. Cell. 2021 Mar 02. PMID: 33713620.
      Citations: 1     Fields:    
    9. Zhou D, Chan JF, Zhou B, Zhou R, Li S, Shan S, Liu L, Zhang AJ, Chen SJ, Chan CC, Xu H, Poon VK, Yuan S, Li C, Chik KK, Chan CC, Cao J, Chan CY, Kwan KY, Du Z, Lau TT, Zhang Q, Zhou J, To KK, Zhang L, Ho DD, Yuen KY, Chen Z. Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies. Cell Host Microbe. 2021 Feb 25. PMID: 33657424.
      Citations: 1     Fields:    
    10. Zhao X, Li C, Liu X, Chiu MC, Wang D, Wei Y, Chu H, Cai JP, Hau-Yee Chan I, Kak-Yuen Wong K, Fuk-Woo Chan J, Kai-Wang To K, Yuen KY, Zhou J. Human Intestinal Organoids Recapitulate Enteric Infections of Enterovirus and Coronavirus. Stem Cell Reports. 2021 03 09; 16(3):493-504. PMID: 33626333.
      Citations:    Fields:    Translation:HumansAnimalsCells
    11. Lau SKP, Lung DC, Wong EYM, Aw-Yong KL, Wong ACP, Luk HKH, Li KSM, Fung J, Chan TTY, Tang JYM, Zhu L, Yip CCY, Wong SCY, Lee RA, Tsang OTY, Yuen KY, Woo PCY. Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup. mSphere. 2021 02 10; 6(1). PMID: 33568452.
      Citations:    Fields:    Translation:HumansCells
    12. Wang J, Liang B, Chen Y, Fuk-Woo Chan J, Yuan S, Ye H, Nie L, Zhou J, Wu Y, Wu M, Huang LS, An J, Warshel A, Yuen KY, Ciechanover A, Huang Z, Xu Y. A new class of a-ketoamide derivatives with potent anticancer and anti-SARS-CoV-2 activities. Eur J Med Chem. 2021 Apr 05; 215:113267. PMID: 33639344.
      Citations:    Fields:    
    13. Li C, Chen YX, Liu FF, Lee AC, Zhao Y, Ye ZH, Cai JP, Chu H, Zhang RQ, Chan KH, Chiu KH, Lung DC, Sridhar S, Hung IF, To KK, Zhang AJ, Chan JF, Yuen KY. Absence of vaccine-enhanced disease with unexpected positive protection against SARS-CoV-2 by inactivated vaccine given within three days of virus challenge in Syrian hamster model. Clin Infect Dis. 2021 Jan 30. PMID: 33515458.
      Citations:    Fields:    
    14. Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, Shuai H, Yang D, Hou Y, Zhang X, Yuen TT, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Chan IH, Sit KY, Foo DC, Wong IY, Ng AT, Cheung TT, Law SY, Au WK, Brindley MA, Chen Z, Kok KH, Chan JF, Yuen KY. Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Nat Commun. 2021 01 08; 12(1):134. PMID: 33420022.
      Citations:    Fields:    Translation:HumansAnimalsCells
    15. Lu L, Fong CH, Zhang AJ, Wu WL, Li IC, Lee AC, Dissanayake TK, Chen L, Hung IF, Chan KH, Chu H, Kok KH, Yuen KY, To KK. Repurposing of Miltefosine as an Adjuvant for Influenza Vaccine. Vaccines (Basel). 2020 Dec 11; 8(4). PMID: 33322574.
    16. Wong SC, Leung M, Tong DW, Lee LL, Leung WL, Chan FW, Chen JH, Hung IF, Yuen KY, Yeung DT, Chung KL, Cheng VC. Infection control challenges in setting up community isolation and treatment facilities for patients with coronavirus disease 2019 (COVID-19): Implementation of directly observed environmental disinfection. Infect Control Hosp Epidemiol. 2020 Dec 07; 1-9. PMID: 33280617.
      Citations:    Fields:    
    17. Chan JF, Zhang AJ, Yuan S, Poon VK, Chan CC, Lee AC, Chan WM, Fan Z, Tsoi HW, Wen L, Liang R, Cao J, Chen Y, Tang K, Luo C, Cai JP, Kok KH, Chu H, Chan KH, Sridhar S, Chen Z, Chen H, To KK, Yuen KY. Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility. Clin Infect Dis. 2020 12 03; 71(9):2428-2446. PMID: 32215622.
      Citations: 197     Fields:    Translation:Animals
    18. Chen JH, Yip CC, Poon RW, Chan KH, Cheng VC, Hung IF, Chan JF, Yuen KY, To KK. Evaluating the use of posterior oropharyngeal saliva in a point-of-care assay for the detection of SARS-CoV-2. Emerg Microbes Infect. 2020 Dec; 9(1):1356-1359. PMID: 32459137.
      Citations: 22     Fields:    Translation:HumansCellsPHPublic Health
    19. Lau SY, Wang P, Mok BW, Zhang AJ, Chu H, Lee AC, Deng S, Chen P, Chan KH, Song W, Chen Z, To KK, Chan JF, Yuen KY, Chen H. Attenuated SARS-CoV-2 variants with deletions at the S1/S2 junction. Emerg Microbes Infect. 2020 Dec; 9(1):837-842. PMID: 32301390.
      Citations: 48     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    20. Lam JY, Yuen CK, Ip JD, Wong WM, To KK, Yuen KY, Kok KH. Loss of orf3b in the circulating SARS-CoV-2 strains. Emerg Microbes Infect. 2020 Dec; 9(1):2685-2696. PMID: 33205709.
      Citations: 1     Fields:    Translation:HumansCells
    21. Li C, Chu H, Liu X, Chiu MC, Zhao X, Wang D, Wei Y, Hou Y, Shuai H, Cai J, Chan JF, Zhou J, Yuen KY. Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target. Emerg Microbes Infect. 2020 Dec; 9(1):2663-2672. PMID: 33179566.
      Citations:    Fields:    Translation:HumansAnimalsCells
    22. Yuen CK, Lam JY, Wong WM, Mak LF, Wang X, Chu H, Cai JP, Jin DY, To KK, Chan JF, Yuen KY, Kok KH. SARS-CoV-2 nsp13, nsp14, nsp15 and orf6 function as potent interferon antagonists. Emerg Microbes Infect. 2020 Dec; 9(1):1418-1428. PMID: 32529952.
      Citations: 45     Fields:    Translation:HumansCellsPHPublic Health
    23. Liu L, To KK, Chan KH, Wong YC, Zhou R, Kwan KY, Fong CH, Chen LL, Choi CY, Lu L, Tsang OT, Leung WS, To WK, Hung IF, Yuen KY, Chen Z. High neutralizing antibody titer in intensive care unit patients with COVID-19. Emerg Microbes Infect. 2020 Dec; 9(1):1664-1670. PMID: 32618497.
      Citations: 24     Fields:    Translation:HumansCellsPHPublic Health
    24. Zhang AJ, Lee AC, Chan JF, Liu F, Li C, Chen Y, Chu H, Lau SY, Wang P, Chan CC, Poon VK, Yuan S, To KK, Chen H, Yuen KY. Co-infection by severe acute respiratory syndrome coronavirus 2 and influenza A(H1N1)pdm09 virus enhances the severity of pneumonia in golden Syrian hamsters. Clin Infect Dis. 2020 Nov 20. PMID: 33216851.
      Citations: 7     Fields:    
    25. Chan JF, Yuan S, Zhang AJ, Poon VK, Chan CC, Lee AC, Fan Z, Li C, Liang R, Cao J, Tang K, Luo C, Cheng VC, Cai JP, Chu H, Chan KH, To KK, Sridhar S, Yuen KY. Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19). Clin Infect Dis. 2020 11 19; 71(16):2139-2149. PMID: 32472679.
      Citations: 39     Fields:    Translation:AnimalsCellsPHPublic Health
    26. Hung IF, Yuen KY. Early triple antiviral therapy for COVID-19 - Authors' reply. Lancet. 2020 11 07; 396(10261):1488. PMID: 33160568.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    27. Ip JD, Kok KH, Chan WM, Chu AW, Wu WL, Yip CC, To WK, Tsang OT, Leung WS, Chik TS, Chan KH, Hung IF, Yuen KY, To KK. Intra-host non-synonymous diversity at a neutralizing antibody epitope of SARS-CoV-2 spike protein N-terminal domain. Clin Microbiol Infect. 2020 Nov 02. PMID: 33144203.
      Citations:    Fields:    
    28. Yuen CK, Wong WM, Mak LF, Wang X, Chu H, Yuen KY, Kok KH. Suppression of SARS-CoV-2 infection in ex-vivo human lung tissues by targeting class III phosphoinositide 3-kinase. J Med Virol. 2021 04; 93(4):2076-2083. PMID: 33026649.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    29. Wang X, Lam JY, Wong WM, Yuen CK, Cai JP, Au SW, Au SW, Chan JF, To KKW, Kok KH, Yuen KY. Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein. mBio. 2020 10 20; 11(5). PMID: 33082264.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    30. Bohn MK, Mancini N, Loh TP, Wang CB, Grimmler M, Gramegna M, Yuen KY, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Erasmus R, Leportier M, Kwon GC, Menezes ME, Patru MM, Singh K, Ferrari M, Najjar O, Horvath AR, Horvath AR, Adeli K, Lippi G. IFCC Interim Guidelines on Molecular Testing of SARS-CoV-2 Infection. Clin Chem Lab Med. 2020 10 07; 58(12):1993-2000. PMID: 33027042.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    31. Bohn MK, Loh TP, Wang CB, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Erasmus R, Leportier M, Grimmler M, Yuen KY, Mancini N, Kwon GC, Menezes ME, Patru MM, Gramegna M, Singh K, Najjar O, Ferrari M, Horvath AR, Horvath AR, Lippi G, Adeli K. IFCC Interim Guidelines on Serological Testing of Antibodies against SARS-CoV-2. Clin Chem Lab Med. 2020 10 07; 58(12):2001-2008. PMID: 33027043.
      Citations: 5     Fields:    Translation:HumansCells
    32. Thompson S, Bohn MK, Mancini N, Loh TP, Wang CB, Grimmler M, Yuen KY, Mueller R, Koch D, Sethi S, Rawlinson WD, Clementi M, Erasmus R, Erasmus R, Leportier M, Kwon GC, Menezes ME, Patru MM, Gramegna M, Singh K, Najjar O, Ferrari M, Lippi G, Adeli K, Horvath AR, Horvath AR. IFCC Interim Guidelines on Biochemical/Hematological Monitoring of COVID-19 Patients. Clin Chem Lab Med. 2020 10 07; 58(12):2009-2016. PMID: 33027044.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    33. Yuan S, Wang R, Chan JF, Zhang AJ, Cheng T, Chik KK, Ye ZW, Wang S, Lee AC, Jin L, Li H, Jin DY, Yuen KY, Sun H. Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters. Nat Microbiol. 2020 11; 5(11):1439-1448. PMID: 33028965.
      Citations: 4     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    34. Chan KH, Yuen KY. Erratum to: COVID-19 epidemic: disentangling the re-emerging controversy about medical facemasks from an epidemiological perspective. Int J Epidemiol. 2020 10 01; 49(5):1760. PMID: 33147615.
      Citations: 1     Fields:    
    35. Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Hou Y, Cai JP, Zhang AJ, Zhou J, Yuan S, To KK, Hung IF, Cheung TT, Ng AT, Hau-Yee Chan I, Wong IY, Law SY, Foo DC, Leung WK, Yuen KY. SARS-CoV-2 Induces a More Robust Innate Immune Response and Replicates Less Efficiently Than SARS-CoV in the Human Intestines: An Ex Vivo Study With Implications on Pathogenesis of COVID-19. Cell Mol Gastroenterol Hepatol. 2021; 11(3):771-781. PMID: 33010495.
      Citations:    Fields:    Translation:HumansCells
    36. Ma BM, Hung IFN, Chan GCW, Chan GCW, Tam AR, Chan SSK, Wong BCK, Wong BCK, Fukuda K, Ohno T, Yuen KY, Chan TM. Case of "relapsing" COVID-19 in a kidney transplant recipient. Nephrology (Carlton). 2020 Dec; 25(12):933-936. PMID: 32951300.
      Citations: 2     Fields:    Translation:Humans
    37. To KK, Hung IF, Chan KH, Yuan S, To WK, Tsang DN, Cheng VC, Chen Z, Kok KH, Yuen KY. Serum antibody profile of a patient with COVID-19 reinfection. Clin Infect Dis. 2020 Sep 23. PMID: 32966566.
      Citations: 5     Fields:    
    38. Lee AC, Zhang AJ, Chan JF, Li C, Fan Z, Liu F, Chen Y, Liang R, Sridhar S, Cai JP, Poon VK, Chan CC, To KK, Yuan S, Zhou J, Chu H, Yuen KY. Oral SARS-CoV-2 Inoculation Establishes Subclinical Respiratory Infection with Virus Shedding in Golden Syrian Hamsters. Cell Rep Med. 2020 Oct 20; 1(7):100121. PMID: 32984855.
    39. Li X, Chan JF, Li KK, Li KK, Tso EY, Yip CC, Sridhar S, Chung TW, Chiu KH, Hung DL, Wu AK, Chau SK, Chau SK, Liu R, Liu R, Lung KC, Tam AR, Cheng VC, To KK, Chan KH, Hung IF, Yuen KY. Detection of SARS-CoV-2 in conjunctival secretions from patients without ocular symptoms. Infection. 2021 Apr; 49(2):257-265. PMID: 32944840.
      Citations: 4     Fields:    
    40. Lim CY, Bohn MK, Lippi G, Ferrari M, Loh TP, Yuen KY, Adeli K, Horvath AR, Horvath AR. Staff rostering, split team arrangement, social distancing (physical distancing) and use of personal protective equipment to minimize risk of workplace transmission during the COVID-19 pandemic: A simulation study. Clin Biochem. 2020 Dec; 86:15-22. PMID: 32926883.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    41. Chan JF, To KK, Yuen KY. A Case Series of Children With Coronavirus Disease 2019: What Have We Learned? Clin Infect Dis. 2020 09 12; 71(6):1552-1553. PMID: 32318718.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    42. Chu H, Chan JF, Wang Y, Yuen TT, Chai Y, Hou Y, Shuai H, Yang D, Hu B, Huang X, Zhang X, Cai JP, Zhou J, Yuan S, Kok KH, To KK, Chan IH, Zhang AJ, Sit KY, Au WK, Yuen KY. Comparative Replication and Immune Activation Profiles of SARS-CoV-2 and SARS-CoV in Human Lungs: An Ex Vivo Study With Implications for the Pathogenesis of COVID-19. Clin Infect Dis. 2020 09 12; 71(6):1400-1409. PMID: 32270184.
      Citations: 163     Fields:    Translation:HumansCellsPHPublic Health
    43. Fong CH, Cai JP, Dissanayake TK, Chen LL, Choi CY, Wong LH, Ng AC, Pang PKP, Pang PKP, Ho DT, Poon RW, Chung TW, Sridhar S, Chan KH, Chan JF, Hung IF, Yuen KY, To KK. Improved Detection of Antibodies against SARS-CoV-2 by Microsphere-Based Antibody Assay. Int J Mol Sci. 2020 Sep 09; 21(18). PMID: 32916926.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    44. Yuan S, Chu H, Huang J, Zhao X, Ye ZW, Lai PM, Wen L, Cai JP, Mo Y, Cao J, Liang R, Poon VK, Sze KH, Zhou J, To KK, Chen Z, Chen H, Jin DY, Chan JF, Yuen KY. Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target. Sci Adv. 2020 08; 6(35):eaba7910. PMID: 32923629.
      Citations: 2     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    45. Zhao H, To KKW, Sze KH, Yung TT, Bian M, Lam H, Yeung ML, Li C, Chu H, Yuen KY. A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2. Nat Commun. 2020 08 25; 11(1):4252. PMID: 32843628.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    46. To KK, Hung IF, Ip JD, Chu AW, Chan WM, Tam AR, Fong CH, Yuan S, Tsoi HW, Ng AC, Lee LL, Wan P, Tso E, To WK, Tsang D, Chan KH, Huang JD, Kok KH, Cheng VC, Yuen KY. COVID-19 re-infection by a phylogenetically distinct SARS-coronavirus-2 strain confirmed by whole genome sequencing. Clin Infect Dis. 2020 Aug 25. PMID: 32840608.
      Citations: 124     Fields:    
    47. Wong SC, Lam GK, AuYeung CH, Chan VW, Wong NL, So SY, Chen JH, Hung IF, Chan JF, Yuen KY, Cheng VC. Absence of nosocomial influenza and respiratory syncytial virus infection in the coronavirus disease 2019 (COVID-19) era: Implication of universal masking in hospitals. Infect Control Hosp Epidemiol. 2021 Feb; 42(2):218-221. PMID: 32799965.
      Citations: 1     Fields:    Translation:Humans
    48. Yip CC, Sridhar S, Leung KH, Ng AC, Chan KH, Chan JF, Tsang OT, Hung IF, Cheng VC, Yuen KY, To KK. Development and Evaluation of Novel and Highly Sensitive Single-Tube Nested Real-Time RT-PCR Assays for SARS-CoV-2 Detection. Int J Mol Sci. 2020 Aug 07; 21(16). PMID: 32784770.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    49. To KK, Yuen KY. Seroprevalence of SARS-CoV-2 in Hong Kong returnees - Authors' reply. Lancet Microbe. 2020 Aug; 1(4):e148. PMID: 33521714.
    50. To KK, Chan WM, Ip JD, Chu AW, Tam AR, Liu R, Liu R, Wu AK, Lung KC, Tsang OT, Lau DP, To WK, Kwan MY, Kwan MY, Yau YS, Ng AC, Yip CC, Chan KH, Tse H, Hung IF, Yuen KY. Unique SARS-CoV-2 clusters causing a large COVID-19 outbreak in Hong Kong. Clin Infect Dis. 2020 Aug 05. PMID: 32756996.
      Citations: 6     Fields:    
    51. Zhou R, To KK, Wong YC, Liu L, Zhou B, Li X, Huang H, Mo Y, Luk TY, Lau TT, Yeung P, Chan WM, Wu AK, Lung KC, Tsang OT, Leung WS, Hung IF, Yuen KY, Chen Z. Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses. Immunity. 2020 10 13; 53(4):864-877.e5. PMID: 32791036.
      Citations: 45     Fields:    Translation:HumansCellsPHPublic Health
    52. Zhang BZ, Chu H, Han S, Shuai H, Deng J, Hu YF, Gong HR, Lee AC, Zou Z, Yau T, Yau T, Wu W, Hung IF, Chan JF, Yuen KY, Huang JD. SARS-CoV-2 infects human neural progenitor cells and brain organoids. Cell Res. 2020 10; 30(10):928-931. PMID: 32753756.
      Citations: 34     Fields:    Translation:HumansCellsPHPublic Health
    53. Yang D, Chu H, Hou Y, Chai Y, Shuai H, Lee AC, Zhang X, Wang Y, Hu B, Huang X, Yuen TT, Cai JP, Zhou J, Yuan S, Zhang AJ, Chan JF, Yuen KY. Attenuated Interferon and Proinflammatory Response in SARS-CoV-2-Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation. J Infect Dis. 2020 08 04; 222(5):734-745. PMID: 32563187.
      Citations: 14     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    54. Chan KH, Yuen KY. COVID-19 epidemic: disentangling the re-emerging controversy about medical facemasks from an epidemiological perspective. Int J Epidemiol. 2020 08 01; 49(4):1063-1066. PMID: 32232402.
      Citations: 19     Fields:    Translation:HumansCellsPHPublic Health
    55. To KK, Tsang OT, Yip CC, Chan KH, Wu TC, Chan JM, Leung WS, Chik TS, Choi CY, Kandamby DH, Lung DC, Tam AR, Poon RW, Fung AY, Hung IF, Cheng VC, Chan JF, Yuen KY. Consistent Detection of 2019 Novel Coronavirus in Saliva. Clin Infect Dis. 2020 07 28; 71(15):841-843. PMID: 32047895.
      Citations: 375     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    56. Citations: 90     Fields:    Translation:HumansCellsPHPublic Health
    57. Chen JH, Yip CC, Chan JF, Poon RW, To KK, Chan KH, Cheng VC, Yuen KY. Clinical Performance of the Luminex NxTAG CoV Extended Panel for SARS-CoV-2 Detection in Nasopharyngeal Specimens from COVID-19 Patients in Hong Kong. J Clin Microbiol. 2020 Jul 23; 58(8). PMID: 32482633.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    58. Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. Nature. 2020 08; 584(7821):450-456. PMID: 32698192.
      Citations: 148     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    59. Shuai H, Chu H, Hou Y, Yang D, Wang Y, Hu B, Huang X, Zhang X, Chai Y, Cai JP, Chan JF, Yuen KY. Differential immune activation profile of SARS-CoV-2 and SARS-CoV infection in human lung and intestinal cells: Implications for treatment with IFN-ß and IFN inducer. J Infect. 2020 10; 81(4):e1-e10. PMID: 32707230.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    60. To KK, Chua GT, Chua GT, Kwok KL, Wong JS, Wong JS, Au DCY, Lam YY, Wong WH, Ho MH, Chan GC, Chui CS, Li X, Tung KT, Wong RS, Tso WW, Wong IC, Wong CS, Fong CH, Chan KH, Yuen KY, Ip P, Kwan MY. False-positive SARS-CoV-2 serology in 3 children with Kawasaki disease. Diagn Microbiol Infect Dis. 2020 Nov; 98(3):115141. PMID: 32795776.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    61. Zhang AJ, Lee AC, Chu H, Chan JF, Fan Z, Li C, Liu F, Chen Y, Yuan S, Poon VK, Chan CC, Cai JP, Wu KL, Sridhar S, Chan YS, Yuen KY. SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters. Clin Infect Dis. 2020 Jul 15. PMID: 32667973.
      Citations: 14     Fields:    
    62. Wong YC, Lau SY, Wang To KK, Mok BWY, Li X, Wang P, Deng S, Woo KF, Du Z, Li C, Zhou J, Woo Chan JF, Yuen KY, Chen H, Chen Z. Natural transmission of bat-like SARS-CoV-2?PRRA variants in COVID-19 patients. Clin Infect Dis. 2020 Jul 10. PMID: 32649739.
      Citations: 3     Fields:    
    63. Chan KH, Sridhar S, Zhang RR, Chu H, Chu H, Fung AY, Chan G, Chan JF, Chan JF, To KK, To KK, Hung IF, Cheng VC, Cheng VC, Yuen KY. Factors affecting stability and infectivity of SARS-CoV-2. J Hosp Infect. 2020 Oct; 106(2):226-231. PMID: 32652214.
      Citations: 23     Fields:    Translation:HumansCellsPHPublic Health
    64. Zhang BZ, Hu YF, Chen LL, Yau T, Yau T, Tong YG, Hu JC, Cai JP, Chan KH, Dou Y, Deng J, Wang XL, Hung IF, To KK, Yuen KY, Huang JD. Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients. Cell Res. 2020 08; 30(8):702-704. PMID: 32612199.
      Citations: 13     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    65. Chu AW, Chan WM, Ip JD, Yip CC, Chan JF, Yuen KY, To KK. Evaluation of simple nucleic acid extraction methods for the detection of SARS-CoV-2 in nasopharyngeal and saliva specimens during global shortage of extraction kits. J Clin Virol. 2020 08; 129:104519. PMID: 32629187.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    66. Chan WM, Ip JD, Chu AW, Yip CC, Lo LS, Chan KH, Ng AC, Poon RW, To WK, Tsang OT, Leung WS, Kwan MY, Kwan MY, Chua GT, Chua GT, Chung TW, Hung IF, Kok KH, Cheng VC, Chan JF, Yuen KY, To KK. Identification of nsp1 gene as the target of SARS-CoV-2 real-time RT-PCR using nanopore whole-genome sequencing. J Med Virol. 2020 11; 92(11):2725-2734. PMID: 32501535.
      Citations: 3     Fields:    Translation:Humans
    67. Hung IF, Cheng VC, Li X, Tam AR, Hung DL, Chiu KH, Yip CC, Cai JP, Ho DT, Wong SC, Leung SS, Chu MY, Tang MO, Chen JH, Poon RW, Fung AY, Zhang RR, Yan EY, Chen LL, Choi CY, Leung KH, Chung TW, Lam SH, Lam TP, Chan JF, Chan KH, Wu TC, Ho PL, Chan JW, Lau CS, To KK, Yuen KY. SARS-CoV-2 shedding and seroconversion among passengers quarantined after disembarking a cruise ship: a case series. Lancet Infect Dis. 2020 09; 20(9):1051-1060. PMID: 32539986.
      Citations: 21     Fields:    Translation:HumansCellsPHPublic Health
    68. To KKW, Yuen KY. Responding to COVID-19 in Hong Kong. Hong Kong Med J. 2020 06; 26(3):164-166. PMID: 32525099.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    69. Yuan S, Chan CC, Chik KK, Tsang JO, Liang R, Cao J, Tang K, Cai JP, Ye ZW, Yin F, To KK, Chu H, Jin DY, Hung IF, Yuen KY, Chan JF. Broad-Spectrum Host-Based Antivirals Targeting the Interferon and Lipogenesis Pathways as Potential Treatment Options for the Pandemic Coronavirus Disease 2019 (COVID-19). Viruses. 2020 06 10; 12(6). PMID: 32532085.
      Citations: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    70. Cheng VC, Wong SC, Chan VW, So SY, Chen JH, Yip CC, Chan KH, Chu H, Chung TW, Sridhar S, To KK, Chan JF, Hung IF, Ho PL, Yuen KY. Air and environmental sampling for SARS-CoV-2 around hospitalized patients with coronavirus disease 2019 (COVID-19). Infect Control Hosp Epidemiol. 2020 11; 41(11):1258-1265. PMID: 32507114.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic Health
    71. Hung DL, Li X, Chiu KH, Yip CC, To KK, Chan JF, Sridhar S, Chung TW, Lung KC, Liu RW, Kwan GS, Hung IF, Cheng VC, Yuen KY. Early-Morning vs Spot Posterior Oropharyngeal Saliva for Diagnosis of SARS-CoV-2 Infection: Implication of Timing of Specimen Collection for Community-Wide Screening. Open Forum Infect Dis. 2020 Jun; 7(6):ofaa210. PMID: 32577428.
    72. Chung TW, Sridhar S, Zhang AJ, Chan KH, Li HL, Wong FK, Ng MY, Tsang RK, Tsang RK, Lee AC, Fan Z, Ho RS, Luk SY, Kan WK, Lam SH, Wu AK, Leung SM, Chan WM, Ng PY, To KK, Cheng VC, Lung KC, Hung IF, Yuen KY. Olfactory Dysfunction in Coronavirus Disease 2019 Patients: Observational Cohort Study and Systematic Review. Open Forum Infect Dis. 2020 Jun; 7(6):ofaa199. PMID: 32548209.
    73. To KK, Cheng VC, Cai JP, Chan KH, Chen LL, Wong LH, Choi CY, Fong CH, Ng AC, Lu L, Luo CT, Situ J, Chung TW, Wong SC, Kwan GS, Sridhar S, Chan JF, Fan CY, Chuang VWM, Kok KH, Hung IF, Yuen KY. Seroprevalence of SARS-CoV-2 in Hong Kong and in residents evacuated from Hubei province, China: a multicohort study. Lancet Microbe. 2020 Jul; 1(3):e111-e118. PMID: 33230504.
    74. Yuan S, Chan JFW, Chik KKH, Chan CCY, Tsang JOL, Liang R, Cao J, Tang K, Chen LL, Wen K, Cai JP, Ye ZW, Lu G, Chu H, Jin DY, Yuen KY. Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system. Pharmacol Res. 2020 09; 159:104960. PMID: 32473310.
      Citations: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    75. Yip CC, Sridhar S, Cheng AK, Leung KH, Choi GK, Chen JH, Poon RW, Chan KH, Wu AK, Chan HS, Chau SK, Chau SK, Chung TW, To KK, Tsang OT, Hung IF, Cheng VC, Yuen KY, Chan JF. Evaluation of the commercially available LightMix® Modular E-gene kit using clinical and proficiency testing specimens for SARS-CoV-2 detection. J Clin Virol. 2020 08; 129:104476. PMID: 32516739.
      Citations: 10     Fields:    Translation:HumansCellsPHPublic Health
    76. Cheng VCC, Wong SC, Chuang VWM, So SYC, Chen JHK, Chen JHK, Sridhar S, To KKW, Chan JFW, Hung IFN, Ho PL, Yuen KY. Absence of nosocomial transmission of coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in the prepandemic phase in Hong Kong. Am J Infect Control. 2020 08; 48(8):890-896. PMID: 32461068.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic Health
    77. Wong SC, AuYeung CH, Lam GK, Leung EY, Chan VW, Yuen KY, Cheng VC. Is it possible to achieve 100 percent hand hygiene compliance during the coronavirus disease 2019 (COVID-19) pandemic? J Hosp Infect. 2020 08; 105(4):779-781. PMID: 32422309.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    78. Zhou J, Li C, Liu X, Chiu MC, Zhao X, Wang D, Wei Y, Lee A, Lee A, Zhang AJ, Chu H, Cai JP, Yip CC, Chan IH, Wong KK, Tsang OT, Chan KH, Chan JF, To KK, Chen H, Yuen KY. Infection of bat and human intestinal organoids by SARS-CoV-2. Nat Med. 2020 07; 26(7):1077-1083. PMID: 32405028.
      Citations: 94     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    79. Hung IF, Lung KC, Tso EY, Liu R, Liu R, Chung TW, Chu MY, Ng YY, Lo J, Chan J, Tam AR, Shum HP, Shum HP, Chan V, Wu AK, Sin KM, Leung WS, Law WL, Lung DC, Sin S, Yeung P, Yip CC, Zhang RR, Fung AY, Yan EY, Leung KH, Ip JD, Chu AW, Chan WM, Ng AC, Lee R, Fung K, Yeung A, Wu TC, Chan JW, Yan WW, Chan WM, Chan JF, Lie AK, Tsang OT, Cheng VC, Que TL, Lau CS, Chan KH, To KK, Yuen KY. Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial. Lancet. 2020 05 30; 395(10238):1695-1704. PMID: 32401715.
      Citations: 372     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    80. Cheng VC, Wong SC, Yuen KY. Estimating Coronavirus Disease 2019 Infection Risk in Health Care Workers. JAMA Netw Open. 2020 05 01; 3(5):e209687. PMID: 32437571.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    81. Cheng VC, Wong SC, Chuang VW, So SY, Chen JH, Sridhar S, To KK, Chan JF, Hung IF, Ho PL, Yuen KY. The role of community-wide wearing of face mask for control of coronavirus disease 2019 (COVID-19) epidemic due to SARS-CoV-2. J Infect. 2020 07; 81(1):107-114. PMID: 32335167.
      Citations: 109     Fields:    Translation:HumansCellsPHPublic Health
    82. Chan JF, Yip CC, To KK, Tang TH, Wong SC, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tsoi HW, Choi GK, Tam AR, Cheng VC, Chan KH, Tsang OT, Yuen KY. Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens. J Clin Microbiol. 2020 04 23; 58(5). PMID: 32132196.
      Citations: 231     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    83. Chu H, Chan JF, Yuen TT, Shuai H, Yuan S, Wang Y, Hu B, Yip CC, Tsang JO, Huang X, Chai Y, Yang D, Hou Y, Chik KK, Zhang X, Fung AY, Tsoi HW, Cai JP, Chan WM, Ip JD, Chu AW, Zhou J, Lung DC, Kok KH, To KK, Tsang OT, Chan KH, Yuen KY. Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study. Lancet Microbe. 2020 May; 1(1):e14-e23. PMID: 32835326.
    84. Wang Q, Zhang Y, Wu L, Niu S, Song C, Zhang Z, Lu G, Qiao C, Qiao C, Hu Y, Yuen KY, Wang Q, Zhou H, Yan J, Qi J. Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2. Cell. 2020 05 14; 181(4):894-904.e9. PMID: 32275855.
      Citations: 471     Fields:    Translation:HumansCells
    85. Yip CC, Ho CC, Chan JF, To KK, Chan HS, Wong SC, Wong SC, Leung KH, Fung AY, Ng AC, Zou Z, Tam AR, Chung TW, Chan KH, Hung IF, Cheng VC, Tsang OT, Tsui SKW, Yuen KY. Development of a Novel, Genome Subtraction-Derived, SARS-CoV-2-Specific COVID-19-nsp2 Real-Time RT-PCR Assay and Its Evaluation Using Clinical Specimens. Int J Mol Sci. 2020 Apr 08; 21(7). PMID: 32276333.
      Citations: 22     Fields:    Translation:HumansCellsPHPublic Health
    86. Cheng VCC, Wong SC, Kwan GSW, Hui WT, Yuen KY. Disinfection of N95 respirators by ionized hydrogen peroxide during pandemic coronavirus disease 2019 (COVID-19) due to SARS-CoV-2. J Hosp Infect. 2020 Jun; 105(2):358-359. PMID: 32277965.
      Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
    87. To KK, Tsang OT, Leung WS, Tam AR, Wu TC, Lung DC, Yip CC, Cai JP, Chan JM, Chik TS, Lau DP, Choi CY, Chen LL, Chan WM, Chan KH, Ip JD, Ng AC, Poon RW, Luo CT, Cheng VC, Chan JF, Hung IF, Chen Z, Chen H, Yuen KY. Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study. Lancet Infect Dis. 2020 05; 20(5):565-574. PMID: 32213337.
      Citations: 795     Fields:    Translation:HumansCellsPHPublic Health
    88. Wu Y, Ho W, Huang Y, Jin DY, Li S, Liu SL, Liu X, Qiu J, Sang Y, Wang Q, Yuen KY, Zheng ZM. SARS-CoV-2 is an appropriate name for the new coronavirus. Lancet. 2020 03 21; 395(10228):949-950. PMID: 32151324.
      Citations: 71     Fields:    Translation:HumansCells
    89. Cheng VCC, Wong SC, Chen JHK, Chen JHK, Yip CCY, Chuang VWM, Tsang OTY, Sridhar S, Chan JFW, Ho PL, Yuen KY. Escalating infection control response to the rapidly evolving epidemiology of the coronavirus disease 2019 (COVID-19) due to SARS-CoV-2 in Hong Kong. Infect Control Hosp Epidemiol. 2020 05; 41(5):493-498. PMID: 32131908.
      Citations: 114     Fields:    Translation:HumansCellsPHPublic Health
    90. Guan WJ, Ni ZY, Hu Y, Liang WH, Ou CQ, He JX, Liu L, Shan H, Lei CL, Hui DSC, Du B, Li LJ, Zeng G, Yuen KY, Chen RC, Tang CL, Wang T, Chen PY, Xiang J, Li SY, Wang JL, Liang ZJ, Peng YX, Wei L, Liu Y, Hu YH, Peng P, Wang JM, Liu JY, Chen Z, Li G, Zheng ZJ, Qiu SQ, Luo J, Ye CJ, Zhu SY, Zhong NS. Clinical Characteristics of Coronavirus Disease 2019 in China. N Engl J Med. 2020 04 30; 382(18):1708-1720. PMID: 32109013.
      Citations: 5942     Fields:    Translation:HumansCellsPHPublic Health
    91. Zhao X, Chu H, Wong BH, Chiu MC, Wang D, Li C, Liu X, Yang D, Poon VK, Cai J, Chan JF, To KK, Zhou J, Yuen KY. Activation of C-Type Lectin Receptor and (RIG)-I-Like Receptors Contributes to Proinflammatory Response in Middle East Respiratory Syndrome Coronavirus-Infected Macrophages. J Infect Dis. 2020 02 03; 221(4):647-659. PMID: 31562757.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    92. Chan JF, Kok KH, Zhu Z, Chu H, To KK, Yuan S, Yuen KY. Genomic characterization of the 2019 novel human-pathogenic coronavirus isolated from a patient with atypical pneumonia after visiting Wuhan. Emerg Microbes Infect. 2020; 9(1):221-236. PMID: 31987001.
      Citations: 638     Fields:    Translation:HumansCells
    93. Chan JF, Yuan S, Kok KH, To KK, Chu H, Yang J, Xing F, Liu J, Yip CC, Poon RW, Tsoi HW, Lo SK, Chan KH, Poon VK, Chan WM, Ip JD, Cai JP, Cheng VC, Chen H, Hui CK, Yuen KY. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet. 2020 02 15; 395(10223):514-523. PMID: 31986261.
      Citations: 2201     Fields:    Translation:HumansCells
    94. Lau SKP, Li KSM, Luk HKH, He Z, Teng JLL, Yuen KY, Wernery U, Woo PCY. Middle East Respiratory Syndrome Coronavirus Antibodies in Bactrian and Hybrid Camels from Dubai. mSphere. 2020 01 22; 5(1). PMID: 31969478.
      Citations: 4     Fields:    Translation:AnimalsCells
    95. Cheng VCC, Wong SC, To KKW, Ho PL, Yuen KY. Preparedness and proactive infection control measures against the emerging novel coronavirus in China. J Hosp Infect. 2020 Mar; 104(3):254-255. PMID: 31962139.
      Citations: 43     Fields:    Translation:HumansCellsPHPublic Health
    96. Lau SKP, Luk HKH, Wong ACP, Fan RYY, Lam CSF, Li KSM, Ahmed SS, Chow FWN, Cai JP, Zhu X, Chan JFW, Lau TCK, Cao K, Li M, Woo PCY, Yuen KY. Identification of a Novel Betacoronavirus (Merbecovirus) in Amur Hedgehogs from China. Viruses. 2019 10 24; 11(11). PMID: 31653070.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    97. Lau SKP, Wong ACP, Zhang L, Luk HKH, Kwok JSL, Ahmed SS, Cai JP, Zhao PSH, Teng JLL, Tsui SKW, Yuen KY, Woo PCY. Novel Bat Alphacoronaviruses in Southern China Support Chinese Horseshoe Bats as an Important Reservoir for Potential Novel Coronaviruses. Viruses. 2019 05 07; 11(5). PMID: 31067830.
      Citations: 5     Fields:    Translation:AnimalsCells
    98. Siu KL, Yuen KS, Castaño-Rodriguez C, Ye ZW, Yeung ML, Fung SY, Yuan S, Chan CP, Yuen KY, Enjuanes L, Jin DY. Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC. FASEB J. 2019 08; 33(8):8865-8877. PMID: 31034780.
      Citations: 96     Fields:    Translation:HumansAnimalsCells
    99. To KKW, Chan KH, Ho J, Pang PKP, Pang PKP, Ho DTY, Ho DTY, Chang ACH, Seng CW, Yip CCY, Cheng VCC, Hung IFN, Yuen KY. Respiratory virus infection among hospitalized adult patients with or without clinically apparent respiratory infection: a prospective cohort study. Clin Microbiol Infect. 2019 Dec; 25(12):1539-1545. PMID: 31004768.
      Citations: 8     Fields:    Translation:HumansCells
    100. Liu L, Wei Q, Lin Q, Fang J, Wang H, Kwok H, Tang H, Nishiura K, Peng J, Tan Z, Wu T, Cheung KW, Chan KH, Alvarez X, Qin C, Lackner A, Perlman S, Yuen KY, Chen Z. Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection. JCI Insight. 2019 02 21; 4(4). PMID: 30830861.
      Citations: 244     Fields:    Translation:HumansAnimalsCells
    101. Yan B, Chu H, Yang D, Sze KH, Lai PM, Yuan S, Shuai H, Wang Y, Kao RY, Chan JF, Yuen KY. Characterization of the Lipidomic Profile of Human Coronavirus-Infected Cells: Implications for Lipid Metabolism Remodeling upon Coronavirus Replication. Viruses. 2019 01 16; 11(1). PMID: 30654597.
      Citations: 44     Fields:    Translation:HumansCells
    102. Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Nat Commun. 2019 01 10; 10(1):120. PMID: 30631056.
      Citations: 48     Fields:    Translation:Cells
    103. Lau SKP, Fan RYY, Luk HKH, Zhu L, Fung J, Li KSM, Wong EYM, Ahmed SS, Chan JFW, Kok RKH, Chan KH, Wernery U, Yuen KY, Woo PCY. Replication of MERS and SARS coronaviruses in bat cells offers insights to their ancestral origins. Emerg Microbes Infect. 2018 Dec 10; 7(1):209. PMID: 30531999.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    104. Lau SKP, Wong EYM, Tsang CC, Ahmed SS, Au-Yeung RKH, Yuen KY, Wernery U, Woo PCY. Discovery and Sequence Analysis of Four Deltacoronaviruses from Birds in the Middle East Reveal Interspecies Jumping with Recombination as a Potential Mechanism for Avian-to-Avian and Avian-to-Mammalian Transmission. J Virol. 2018 08 01; 92(15). PMID: 29769348.
      Citations: 20     Fields:    Translation:AnimalsCells
    105. Lau SKP, Zhang L, Luk HKH, Xiong L, Peng X, Li KSM, He X, Zhao PS, Fan RYY, Wong ACP, Ahmed SS, Cai JP, Chan JFW, Sun Y, Jin D, Chen H, Lau TCK, Kok RKH, Li W, Yuen KY, Woo PCY. Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding. J Infect Dis. 2018 06 20; 218(2):197-207. PMID: 29346682.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    106. Chu H, Chan CM, Zhang X, Wang Y, Yuan S, Zhou J, Au-Yeung RK, Sze KH, Yang D, Shuai H, Hou Y, Li C, Zhao X, Poon VK, Leung SP, Yeung ML, Yan J, Lu G, Jin DY, Gao GF, Chan JF, Yuen KY. Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells. J Biol Chem. 2018 07 27; 293(30):11709-11726. PMID: 29887526.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    107. Woo PCY, Lau SKP, Chen Y, Wong EYM, Chan KH, Chen H, Zhang L, Xia N, Yuen KY. Rapid detection of MERS coronavirus-like viruses in bats: pote1ntial for tracking MERS coronavirus transmission and animal origin. Emerg Microbes Infect. 2018 Mar 07; 7(1):18. PMID: 29511173.
      Citations: 6     Fields:    Translation:AnimalsCells
    108. Zhang SF, Tuo JL, Huang XB, Zhu X, Zhang DM, Zhou K, Yuan L, Luo HJ, Zheng BJ, Yuen KY, Li MF, Cao KY, Xu L. Epidemiology characteristics of human coronaviruses in patients with respiratory infection symptoms and phylogenetic analysis of HCoV-OC43 during 2010-2015 in Guangzhou. PLoS One. 2018; 13(1):e0191789. PMID: 29377913.
      Citations: 35     Fields:    Translation:HumansCells
    109. Obameso JO, Li H, Jia H, Han M, Zhu S, Huang C, Zhao Y, Zhao M, Bai Y, Yuan F, Zhao H, Peng X, Xu W, Tan W, Zhao Y, Yuen KY, Liu WJ, Lu L, Gao GF. The persistent prevalence and evolution of cross-family recombinant coronavirus GCCDC1 among a bat population: a two-year follow-up. Sci China Life Sci. 2017 12; 60(12):1357-1363. PMID: 29299855.
      Citations: 3     Fields:    Translation:AnimalsCells
    110. Zhou J, Li C, Zhao G, Chu H, Wang D, Yan HH, Poon VK, Wen L, Wong BH, Zhao X, Chiu MC, Yang D, Wang Y, Au-Yeung RKH, Chan IH, Sun S, Chan JF, To KK, Memish ZA, Corman VM, Drosten C, Hung IF, Zhou Y, Leung SY, Yuen KY. Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus. Sci Adv. 2017 11; 3(11):eaao4966. PMID: 29152574.
      Citations: 113     Fields:    Translation:HumansAnimalsCells
    111. Woo PC, Lau SK, Tsang CC, Lau CC, Wong PC, Chow FW, Fong JY, Yuen KY. Coronavirus HKU15 in respiratory tract of pigs and first discovery of coronavirus quasispecies in 5'-untranslated region. Emerg Microbes Infect. 2017 Jun 21; 6(6):e53. PMID: 28634353.
      Citations: 12     Fields:    Translation:AnimalsCells
    112. Woo PCY, Lau SKP, Tsoi HW, Patteril NG, Yeung HC, Joseph S, Wong EYM, Muhammed R, Chow FWN, Wernery U, Yuen KY. Two novel dromedary camel bocaparvoviruses from dromedaries in the Middle East with unique genomic features. J Gen Virol. 2017 Jun; 98(6):1349-1359. PMID: 28613145.
      Citations: 4     Fields:    Translation:AnimalsCells
    113. To KK, Lu L, Lu L, Yip CC, Poon RW, Fung AM, Cheng A, Lui DH, Ho DT, Ho DT, Hung IF, Chan KH, Yuen KY. Additional molecular testing of saliva specimens improves the detection of respiratory viruses. Emerg Microbes Infect. 2017 Jun 07; 6(6):e49. PMID: 28588283.
      Citations: 21     Fields:    Translation:HumansCells
    114. Cheung NN, Lai KK, Dai J, Kok KH, Chen H, Chan KH, Yuen KY, Kao RYT. Broad-spectrum inhibition of common respiratory RNA viruses by a pyrimidine synthesis inhibitor with involvement of the host antiviral response. J Gen Virol. 2017 May; 98(5):946-954. PMID: 28555543.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    115. Han X, Qi J, Song H, Wang Q, Zhang Y, Wu Y, Lu G, Yuen KY, Shi Y, Gao GF. Structure of the S1 subunit C-terminal domain from bat-derived coronavirus HKU5 spike protein. Virology. 2017 07; 507:101-109. PMID: 28432925.
      Citations: 5     Fields:    Translation:AnimalsCells
    116. Lau SK, Wernery R, Wong EY, Joseph S, Tsang AK, Patteril NA, Elizabeth SK, Chan KH, Muhammed R, Kinne J, Yuen KY, Wernery U, Woo PC. Polyphyletic origin of MERS coronaviruses and isolation of a novel clade A strain from dromedary camels in the United Arab Emirates. Emerg Microbes Infect. 2016 Dec 21; 5(12):e128. PMID: 27999424.
      Citations: 17     Fields:    Translation:AnimalsCells
    117. Chan CM, Chu H, Wang Y, Wong BH, Zhao X, Zhou J, Yang D, Leung SP, Chan JF, Yeung ML, Yan J, Lu G, Gao GF, Yuen KY. Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Is an Important Surface Attachment Factor That Facilitates Entry of Middle East Respiratory Syndrome Coronavirus. J Virol. 2016 10 15; 90(20):9114-27. PMID: 27489282.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    118. Woo PC, Lau SK, Fan RY, Lau CC, Wong EY, Joseph S, Tsang AK, Wernery R, Yip CC, Tsang CC, Wernery U, Yuen KY. Isolation and Characterization of Dromedary Camel Coronavirus UAE-HKU23 from Dromedaries of the Middle East: Minimal Serological Cross-Reactivity between MERS Coronavirus and Dromedary Camel Coronavirus UAE-HKU23. Int J Mol Sci. 2016 May 07; 17(5). PMID: 27164099.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    119. Chen JHK, Chen JHK, Lam HY, Yip CCY, Wong SCY, Chan JFW, Ma ESK, Ma ESK, Cheng VCC, Tang BSF, Yuen KY. Clinical Evaluation of the New High-Throughput Luminex NxTAG Respiratory Pathogen Panel Assay for Multiplex Respiratory Pathogen Detection. J Clin Microbiol. 2016 07; 54(7):1820-1825. PMID: 27122380.
      Citations: 19     Fields:    Translation:HumansCells
    120. Lui PY, Wong LY, Fung CL, Siu KL, Yeung ML, Yuen KS, Chan CP, Woo PC, Yuen KY, Jin DY. Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3. Emerg Microbes Infect. 2016 Apr 20; 5:e39. PMID: 27094905.
      Citations: 41     Fields:    Translation:HumansCells
    121. Lau SK, Tsang AK, Shakeel Ahmed S, Mahbub Alam M, Ahmed Z, Wong PC, Yuen KY, Woo PC. First genome sequences of buffalo coronavirus from water buffaloes in Bangladesh. New Microbes New Infect. 2016 May; 11:54-6. PMID: 27274850.
    122. Zhao H, Zhou J, Zhang K, Chu H, Liu D, Poon VK, Chan CC, Leung HC, Fai N, Lin YP, Zhang AJ, Jin DY, Yuen KY, Zheng BJ. A novel peptide with potent and broad-spectrum antiviral activities against multiple respiratory viruses. Sci Rep. 2016 Feb 25; 6:22008. PMID: 26911565.
      Citations: 35     Fields:    Translation:AnimalsCells
    123. Yip CC, Lam CS, Luk HK, Wong EY, Lee RA, So LY, Chan KH, Cheng VC, Yuen KY, Woo PC, Lau SK. A six-year descriptive epidemiological study of human coronavirus infections in hospitalized patients in Hong Kong. Virol Sin. 2016 Feb; 31(1):41-8. PMID: 26920709.
      Citations: 9     Fields:    Translation:HumansCells
    124. Yeung ML, Yao Y, Jia L, Chan JF, Chan KH, Cheung KF, Chen H, Poon VK, Tsang AK, To KK, Yiu MK, Teng JL, Chu H, Zhou J, Zhang Q, Deng W, Lau SK, Lau JY, Woo PC, Chan TM, Yung S, Zheng BJ, Jin DY, Mathieson PW, Qin C, Yuen KY. MERS coronavirus induces apoptosis in kidney and lung by upregulating Smad7 and FGF2. Nat Microbiol. 2016 Feb 22; 1:16004. PMID: 27572168.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    125. Zumla A, Chan JF, Azhar EI, Hui DS, Yuen KY. Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 05; 15(5):327-47. PMID: 26868298.
      Citations: 466     Fields:    Translation:HumansCells
    126. Zhou J, Chu H, Chan JF, Yuen KY. Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesis. Virol J. 2015 Dec 22; 12:218. PMID: 26690369.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    127. Wernery U, El Rasoul IH, Wong EY, Joseph M, Chen Y, Jose S, Tsang AK, Patteril NA, Chen H, Elizabeth SK, Yuen KY, Joseph S, Xia N, Wernery R, Lau SK, Woo PC. A phylogenetically distinct Middle East respiratory syndrome coronavirus detected in a dromedary calf from a closed dairy herd in Dubai with rising seroprevalence with age. Emerg Microbes Infect. 2015 Dec 02; 4(12):e74. PMID: 26632876.
      Citations: 12     Fields:    Translation:AnimalsCellsPHPublic Health
    128. Li Y, Wan Y, Liu P, Zhao J, Lu G, Qi J, Wang Q, Lu X, Wu Y, Liu W, Zhang B, Yuen KY, Perlman S, Gao GF, Yan J. A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Res. 2015 Nov; 25(11):1237-49. PMID: 26391698.
      Citations: 59     Fields:    Translation:AnimalsCells
    129. Dimitrov DS, Jiang S, Ying T, Tseng CT, Zhang L, Yuen KY. No evidence for a superior platform to develop therapeutic antibodies rapidly in response to MERS-CoV and other emerging viruses. Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37):E5115. PMID: 26318165.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    130. Lau SK, Feng Y, Chen H, Luk HK, Yang WH, Li KS, Zhang YZ, Huang Y, Song ZZ, Chow WN, Fan RY, Ahmed SS, Yeung HC, Lam CS, Cai JP, Wong SS, Chan JF, Yuen KY, Zhang HL, Woo PC. Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination. J Virol. 2015 Oct; 89(20):10532-47. PMID: 26269185.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    131. Chu H, Zhou J, Wong BH, Li C, Chan JF, Cheng ZS, Yang D, Wang D, Lee AC, Li C, Yeung ML, Cai JP, Chan IH, Ho WK, To KK, Zheng BJ, Yao Y, Qin C, Yuen KY. Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis Pathways. J Infect Dis. 2016 Mar 15; 213(6):904-14. PMID: 26203058.
      Citations: 150     Fields:    Translation:HumansAnimalsCells
    132. Chan JF, Yao Y, Yeung ML, Deng W, Bao L, Jia L, Li F, Xiao C, Gao H, Yu P, Cai JP, Chu H, Zhou J, Chen H, Qin C, Yuen KY. Treatment With Lopinavir/Ritonavir or Interferon-ß1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset. J Infect Dis. 2015 Dec 15; 212(12):1904-13. PMID: 26198719.
      Citations: 242     Fields:    Translation:AnimalsCells
    133. Woo PCY, Lau SKP, Teng JLL, Tsang AKL, Joseph S, Xie J, Jose S, Fan RYY, Wernery U, Yuen KY. A novel astrovirus from dromedaries in the Middle East. J Gen Virol. 2015 Sep; 96(9):2697-2707. PMID: 26296576.
      Citations: 7     Fields:    Translation:AnimalsCells
    134. Chan JF, Choi GK, Tsang AK, Tee KM, Lam HY, Yip CC, To KK, Cheng VC, Yeung ML, Lau SK, Woo PC, Chan KH, Tang BS, Yuen KY. Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic Coronaviruses. J Clin Microbiol. 2015 Aug; 53(8):2722-6. PMID: 26019210.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    135. Chen Y, Chan KH, Kang Y, Chen H, Luk HK, Poon RW, Chan JF, Yuen KY, Xia N, Lau SK, Woo PC. A sensitive and specific antigen detection assay for Middle East respiratory syndrome coronavirus. Emerg Microbes Infect. 2015 Apr; 4(4):e26. PMID: 26421268.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    136. Chan JF, Lau SK, To KK, Cheng VC, Woo PC, Yuen KY. Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like disease. Clin Microbiol Rev. 2015 Apr; 28(2):465-522. PMID: 25810418.
      Citations: 299     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    137. Woo PC, Lau SK, Li T, Jose S, Yip CC, Huang Y, Wong EY, Fan RY, Cai JP, Wernery U, Yuen KY. A novel dromedary camel enterovirus in the family Picornaviridae from dromedaries in the Middle East. J Gen Virol. 2015 Jul; 96(Pt 7):1723-31. PMID: 25805410.
      Citations: 9     Fields:    Translation:AnimalsCells
    138. Lau SK, Woo PC, Li KS, Tsang AK, Fan RY, Luk HK, Cai JP, Chan KH, Zheng BJ, Wang M, Yuen KY. Discovery of a novel coronavirus, China Rattus coronavirus HKU24, from Norway rats supports the murine origin of Betacoronavirus 1 and has implications for the ancestor of Betacoronavirus lineage A. J Virol. 2015 Mar; 89(6):3076-92. PMID: 25552712.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    139. Woo PC, Lau SK, Teng JL, Tsang AK, Joseph M, Wong EY, Tang Y, Sivakumar S, Bai R, Wernery R, Wernery U, Yuen KY. Metagenomic analysis of viromes of dromedary camel fecal samples reveals large number and high diversity of circoviruses and picobirnaviruses. Virology. 2014 Dec; 471-473:117-25. PMID: 25461537.
      Citations: 17     Fields:    Translation:AnimalsCells
    140. Wang Q, Qi J, Yuan Y, Xuan Y, Han P, Wan Y, Ji W, Ji W, Li Y, Li Y, Wu Y, Wu Y, Wang J, Wang J, Iwamoto A, Woo PC, Yuen KY, Yan J, Lu G, Gao GF. Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26. . 2014 Sep 10; 16(3):328-37. PMID: 25211075.
    141. Ying T, Du L, Ju TW, Prabakaran P, Lau CC, Lu L, Liu Q, Wang L, Feng Y, Wang Y, Zheng BJ, Yuen KY, Jiang S, Dimitrov DS. Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies. J Virol. 2014 Jul; 88(14):7796-805. PMID: 24789777.
      Citations: 99     Fields:    Translation:HumansCells
    142. Jiang L, Wang N, Zuo T, Shi X, Poon KM, Wu Y, Gao F, Li D, Wang R, Guo J, Fu L, Yuen KY, Zheng BJ, Wang X, Zhang L. Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoprotein. Sci Transl Med. 2014 Apr 30; 6(234):234ra59. PMID: 24778414.
      Citations: 92     Fields:    Translation:HumansCells
    143. Woo PC, Lau SK, Wernery U, Wong EY, Tsang AK, Johnson B, Yip CC, Lau CC, Sivakumar S, Cai JP, Fan RY, Chan KH, Mareena R, Yuen KY. Novel betacoronavirus in dromedaries of the Middle East, 2013. Emerg Infect Dis. 2014 Apr; 20(4):560-72. PMID: 24655427.
      Citations: 41     Fields:    Translation:AnimalsCells
    144. Chu H, Zhou J, Wong BH, Li C, Cheng ZS, Lin X, Poon VK, Sun T, Lau CC, Chan JF, To KK, Chan KH, Lu L, Zheng BJ, Yuen KY. Productive replication of Middle East respiratory syndrome coronavirus in monocyte-derived dendritic cells modulates innate immune response. Virology. 2014 Apr; 454-455:197-205. PMID: 24725946.
      Citations: 71     Fields:    Translation:HumansCells
    145. Siu KL, Yeung ML, Kok KH, Yuen KS, Kew C, Lui PY, Chan CP, Tse H, Woo PC, Yuen KY, Jin DY. Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response. J Virol. 2014 May; 88(9):4866-76. PMID: 24522921.
      Citations: 75     Fields:    Translation:HumansCells
    146. Lu L, Liu Q, Zhu Y, Chan KH, Qin L, Li Y, Wang Q, Chan JF, Du L, Yu F, Ma C, Ye S, Yuen KY, Zhang R, Jiang S. Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor. Nat Commun. 2014; 5:3067. PMID: 24473083.
      Citations: 125     Fields:    Translation:HumansCells
    147. Woo PC, Lau SK, Lam CS, Tsang AK, Hui SW, Fan RY, Martelli P, Yuen KY. Discovery of a novel bottlenose dolphin coronavirus reveals a distinct species of marine mammal coronavirus in Gammacoronavirus. J Virol. 2014 Jan; 88(2):1318-31. PMID: 24227844.
      Citations: 36     Fields:    Translation:AnimalsCells
    148. Yao Y, Bao L, Deng W, Xu L, Li F, Lv Q, Yu P, Chen T, Xu Y, Zhu H, Yuan J, Gu S, Wei Q, Chen H, Yuen KY, Qin C. An animal model of MERS produced by infection of rhesus macaques with MERS coronavirus. J Infect Dis. 2014 Jan 15; 209(2):236-42. PMID: 24218506.
      Citations: 59     Fields:    Translation:AnimalsCells
    149. Chan JF, Chan KH, Kao RY, To KK, Zheng BJ, Li CP, Li PT, Dai J, Dai J, Mok FK, Chen H, Chen H, Hayden FG, Yuen KY. Broad-spectrum antivirals for the emerging Middle East respiratory syndrome coronavirus. J Infect. 2013 Dec; 67(6):606-16. PMID: 24096239.
      Citations: 125     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    150. Lau SKP, Lau CCY, Chan KH, Li CPY, Chen H, Jin DY, Chan JFW, Woo PCY, Yuen KY. Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment. J Gen Virol. 2013 Dec; 94(Pt 12):2679-2690. PMID: 24077366.
      Citations: 134     Fields:    Translation:HumansCells
    151. Zhou J, Chu H, Li C, Wong BH, Cheng ZS, Poon VK, Sun T, Lau CC, Wong KK, Chan JY, Chan JF, To KK, Chan KH, Zheng BJ, Yuen KY. Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesis. J Infect Dis. 2014 May 01; 209(9):1331-42. PMID: 24065148.
      Citations: 140     Fields:    Translation:HumansAnimalsCells
    152. Cheng VC, Chan JF, To KK, Yuen KY. Clinical management and infection control of SARS: lessons learned. Antiviral Res. 2013 Nov; 100(2):407-19. PMID: 23994190.
      Citations: 52     Fields:    Translation:HumansPHPublic Health
    153. To KK, Hung IF, Chan JF, Yuen KY. From SARS coronavirus to novel animal and human coronaviruses. J Thorac Dis. 2013 Aug; 5 Suppl 2:S103-8. PMID: 23977429.
    154. Chan JF, Chan KH, Yuen KY. Reply to Leow. J Infect Dis. 2013 Oct 15; 208(8):1351-2. PMID: 23878323.
      Citations:    Fields:    Translation:HumansCells
    155. Meng W, Pan W, Zhang AJ, Zhang AJ, Li Z, Wei G, Feng L, Dong Z, Li C, Hu X, Sun C, Luo Q, Yuen KY, Zhong N, Chen L. Rapid Generation of Human-Like Neutralizing Monoclonal Antibodies in Urgent Preparedness for Influenza Pandemics and Virulent Infectious Diseases. PLoS One. 2013; 8(6):e66276. PMID: 23824680.
      Citations: 10     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    156. Chan JF, To KK, Tse H, Jin DY, Yuen KY. Interspecies transmission and emergence of novel viruses: lessons from bats and birds. Trends Microbiol. 2013 Oct; 21(10):544-55. PMID: 23770275.
      Citations: 126     Fields:    Translation:HumansAnimalsCells
    157. Lau SK, Li KS, Tsang AK, Lam CS, Ahmed S, Chen H, Chan KH, Woo PC, Yuen KY. Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: implications for the origin of the novel Middle East respiratory syndrome coronavirus. J Virol. 2013 Aug; 87(15):8638-50. PMID: 23720729.
      Citations: 98     Fields:    Translation:AnimalsCells
    158. Chan KH, Chan JF, Tse H, Chen H, Lau CC, Cai JP, Tsang AK, Xiao X, To KK, Lau SK, Woo PC, Zheng BJ, Wang M, Yuen KY. Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests. J Infect. 2013 Aug; 67(2):130-40. PMID: 23583636.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    159. Chan JF, Chan KH, Choi GK, To KK, Tse H, Cai JP, Yeung ML, Cheng VC, Chen H, Che XY, Lau SK, Woo PC, Yuen KY. Differential cell line susceptibility to the emerging novel human betacoronavirus 2c EMC/2012: implications for disease pathogenesis and clinical manifestation. J Infect Dis. 2013 Jun 01; 207(11):1743-52. PMID: 23532101.
      Citations: 93     Fields:    Translation:HumansCells
    160. Woo PC, Lau SK, Li KS, Tsang AK, Yuen KY. Genetic relatedness of the novel human group C betacoronavirus to Tylonycteris bat coronavirus HKU4 and Pipistrellus bat coronavirus HKU5. Emerg Microbes Infect. 2012 Nov; 1(11):e35. PMID: 26038405.
      Citations: 37     Fields:    
    161. Chan JF, Li KS, To KK, Cheng VC, Chen H, Yuen KY. Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic? J Infect. 2012 Dec; 65(6):477-89. PMID: 23072791.
      Citations: 69     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    162. Xu L, He X, Zhang DM, Feng FS, Wang Z, Guan LL, Wu JH, Zhou R, Zheng BJ, Yuen KY, Li MF, Cao KY. Surveillance and genome analysis of human bocavirus in patients with respiratory infection in Guangzhou, China. PLoS One. 2012; 7(9):e44876. PMID: 22984581.
      Citations: 9     Fields:    Translation:HumansCells
    163. Lau SK, Li KS, Tsang AK, Shek CT, Wang M, Choi GK, Guo R, Wong BH, Poon RW, Lam CS, Wang SY, Fan RY, Chan KH, Zheng BJ, Woo PC, Yuen KY. Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders. J Virol. 2012 Nov; 86(21):11906-18. PMID: 22933277.
      Citations: 33     Fields:    Translation:AnimalsCells
    164. Cheng VC, To KK, Tse H, Hung IF, Yuen KY. Two years after pandemic influenza A/2009/H1N1: what have we learned? Clin Microbiol Rev. 2012 Apr; 25(2):223-63. PMID: 22491771.
      Citations: 55     Fields:    Translation:HumansCellsPHPublic Health
    165. Lau SK, Woo PC, Yip CC, Fan RY, Huang Y, Wang M, Guo R, Lam CS, Tsang AK, Lai KK, Chan KH, Che XY, Zheng BJ, Yuen KY. Isolation and characterization of a novel Betacoronavirus subgroup A coronavirus, rabbit coronavirus HKU14, from domestic rabbits. J Virol. 2012 May; 86(10):5481-96. PMID: 22398294.
      Citations: 52     Fields:    Translation:AnimalsCells
    166. Woo PC, Yuen KY, Lau SK. Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study. Hong Kong Med J. 2012 Feb; 18 Suppl 2:22-4. PMID: 22311356.
      Citations: 7     Fields:    Translation:HumansCells
    167. Yuen KY, Lau SK, Woo PC. Wild animal surveillance for coronavirus HKU1 and potential variants of other coronaviruses. Hong Kong Med J. 2012 Feb; 18 Suppl 2:25-6. PMID: 22311357.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    168. Woo PC, Lau SK, Lam CS, Lau CC, Tsang AK, Lau JH, Bai R, Teng JL, Tsang CC, Wang M, Zheng BJ, Chan KH, Yuen KY. Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavirus. J Virol. 2012 Apr; 86(7):3995-4008. PMID: 22278237.
      Citations: 399     Fields:    Translation:HumansAnimalsCells
    169. Chan KH, Chan KH, Peiris JS, Lam SY, Poon LL, Yuen KY, Seto WH. The Effects of Temperature and Relative Humidity on the Viability of the SARS Coronavirus. Adv Virol. 2011; 2011:734690. PMID: 22312351.
    170. Lau SK, Lee P, Tsang AK, Yip CC, Tse H, Lee RA, So LY, Lau YL, Chan KH, Woo PC, Yuen KY. Molecular epidemiology of human coronavirus OC43 reveals evolution of different genotypes over time and recent emergence of a novel genotype due to natural recombination. J Virol. 2011 Nov; 85(21):11325-37. PMID: 21849456.
      Citations: 81     Fields:    Translation:HumansCells
    171. Woo PC, Huang Y, Lau SK, Yuen KY. Coronavirus genomics and bioinformatics analysis. Viruses. 2010 Aug; 2(8):1804-20. PMID: 21994708.
      Citations: 177     Fields:    
    172. Lau SK, Poon RW, Wong BH, Wang M, Huang Y, Xu H, Guo R, Li KS, Gao K, Chan KH, Zheng BJ, Woo PC, Yuen KY. Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup. J Virol. 2010 Nov; 84(21):11385-94. PMID: 20702646.
      Citations: 46     Fields:    Translation:AnimalsCells
    173. Lau SK, Li KS, Huang Y, Shek CT, Tse H, Wang M, Choi GK, Xu H, Lam CS, Guo R, Chan KH, Zheng BJ, Woo PC, Yuen KY. Ecoepidemiology and complete genome comparison of different strains of severe acute respiratory syndrome-related Rhinolophus bat coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events. J Virol. 2010 Mar; 84(6):2808-19. PMID: 20071579.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    174. Hung IF, Lau SK, Woo PC, Yuen KY. Viral loads in clinical specimens and SARS manifestations. Hong Kong Med J. 2009 Dec; 15 Suppl 9:20-2. PMID: 20393220.
      Citations: 8     Fields:    Translation:HumansCellsPHPublic Health
    175. Tang BS, Chan KH, Cheng VC, Yuen KY. Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by SARS coronavirus and human coronavirus 229E. Hong Kong Med J. 2009 Dec; 15 Suppl 9:23-6. PMID: 20393221.
      Citations: 2     Fields:    Translation:HumansCells
    176. Woo PC, Lau SK, Yuen KY. Clinical features and molecular epidemiology of coronavirus-HKU1-associated community-acquired pneumonia. Hong Kong Med J. 2009 Dec; 15 Suppl 9:46-7. PMID: 20393227.
      Citations: 4     Fields:    Translation:HumansCells
    177. Woo PC, Lau SK, Huang Y, Yuen KY. Coronavirus diversity, phylogeny and interspecies jumping. Exp Biol Med (Maywood). 2009 Oct; 234(10):1117-27. PMID: 19546349.
      Citations: 192     Fields:    Translation:HumansAnimalsCells
    178. Woo PC, Lau SK, Yip CC, Huang Y, Yuen KY. More and More Coronaviruses: Human Coronavirus HKU1. Viruses. 2009 Jun; 1(1):57-71. PMID: 21994538.
      Citations: 23     Fields:    
    179. He ML, Zheng BJ, Chen Y, Wong KL, Huang JD, Lin MC, Yuen KY, Sung JJ, Kung HF. Development of interfering RNA agents to inhibit SARS-associated coronavirus infection and replication. Hong Kong Med J. 2009 Jun; 15(3 Suppl 4):28-31. PMID: 19509435.
      Citations: 9     Fields:    Translation:AnimalsCells
    180. Wang W, Wei L, Yang A, He T, Yuen KY, Chen C, Rao Z. Expression, crystallization and preliminary crystallographic study of human coronavirus HKU1 nonstructural protein 9. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 May 01; 65(Pt 5):526-8. PMID: 19407394.
      Citations: 1     Fields:    Translation:Cells
    181. Siu KL, Kok KH, Ng MJ, Poon VKM, Yuen KY, Zheng BJ, Jin DY. Severe acute respiratory syndrome coronavirus M protein inhibits type I interferon production by impeding the formation of TRAF3.TANK.TBK1/IKKepsilon complex. J Biol Chem. 2009 Jun 12; 284(24):16202-16209. PMID: 19380580.
      Citations: 114     Fields:    Translation:HumansCells
    182. Chan CM, Tse H, Wong SS, Woo PC, Lau SK, Chen L, Zheng BJ, Huang JD, Yuen KY. Examination of seroprevalence of coronavirus HKU1 infection with S protein-based ELISA and neutralization assay against viral spike pseudotyped virus. J Clin Virol. 2009 May; 45(1):54-60. PMID: 19342289.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    183. Yuen KY, Woo PC, Lau SK. An oral mucosal DNA vaccine for SARS coronavirus infections. Hong Kong Med J. 2009 Feb; 15 Suppl 2:41-2. PMID: 19258634.
      Citations:    Fields:    Translation:AnimalsCells
    184. Chan CM, Lau SK, Woo PC, Tse H, Zheng BJ, Chen L, Huang JD, Yuen KY. Identification of major histocompatibility complex class I C molecule as an attachment factor that facilitates coronavirus HKU1 spike-mediated infection. J Virol. 2009 Jan; 83(2):1026-35. PMID: 18987136.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    185. Woo PC, Lau SK, Lam CS, Lai KK, Huang Y, Lee P, Luk GS, Dyrting KC, Chan KH, Yuen KY. Comparative analysis of complete genome sequences of three avian coronaviruses reveals a novel group 3c coronavirus. J Virol. 2009 Jan; 83(2):908-17. PMID: 18971277.
      Citations: 78     Fields:    Translation:AnimalsCells
    186. Chan CM, Woo PC, Lau SK, Tse H, Chen HL, Li F, Zheng BJ, Chen L, Huang JD, Yuen KY. Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection. Exp Biol Med (Maywood). 2008 Dec; 233(12):1527-36. PMID: 18849544.
      Citations: 11     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    187. Zheng BJ, Du LY, Zhao GY, Lin YP, Sui HY, Chan C, Ma S, Guan Y, Yuen KY. Studies of SARS virus vaccines. Hong Kong Med J. 2008 Aug; 14 Suppl 4:39-43. PMID: 18708674.
      Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    188. Wong SS, Yuen KY. The management of coronavirus infections with particular reference to SARS. J Antimicrob Chemother. 2008 Sep; 62(3):437-41. PMID: 18565970.
      Citations: 40     Fields:    Translation:HumansCellsPHPublic Health
    189. Du L, Zhao G, Lin Y, Chan C, He Y, Jiang S, Wu C, Jin DY, Yuen KY, Zhou Y, Zheng BJ. Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection. Vaccine. 2008 Mar 20; 26(13):1644-51. PMID: 18289745.
      Citations: 37     Fields:    Translation:AnimalsCells
    190. Du L, Zhao G, Lin Y, Sui H, Chan C, Ma S, He Y, Jiang S, Wu C, Yuen KY, Jin DY, Zhou Y, Zheng BJ. Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong mucosal immune responses and provides long-term protection against SARS-CoV infection. J Immunol. 2008 Jan 15; 180(2):948-56. PMID: 18178835.
      Citations: 53     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    191. Huang Y, Lau SK, Woo PC, Yuen KY. CoVDB: a comprehensive database for comparative analysis of coronavirus genes and genomes. Nucleic Acids Res. 2008 Jan; 36(Database issue):D504-11. PMID: 17913743.
      Citations: 24     Fields:    Translation:Cells
    192. Cheng VC, Lau SK, Woo PC, Yuen KY. Severe acute respiratory syndrome coronavirus as an agent of emerging and reemerging infection. Clin Microbiol Rev. 2007 Oct; 20(4):660-94. PMID: 17934078.
      Citations: 261     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    193. Woo PC, Wong BH, Huang Y, Lau SK, Yuen KY. Cytosine deamination and selection of CpG suppressed clones are the two major independent biological forces that shape codon usage bias in coronaviruses. Virology. 2007 Dec 20; 369(2):431-42. PMID: 17881030.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    194. Lau SK, Yip CC, Que TL, Lee RA, Au-Yeung RK, Zhou B, So LY, Lau YL, Chan KH, Woo PC, Yuen KY. Clinical and molecular epidemiology of human bocavirus in respiratory and fecal samples from children in Hong Kong. J Infect Dis. 2007 Oct 01; 196(7):986-93. PMID: 17763318.
      Citations: 56     Fields:    Translation:HumansCells
    195. Lau SK, Woo PC, Li KS, Huang Y, Huang Y, Wang M, Wang M, Lam CS, Xu H, Xu H, Guo R, Chan KH, Zheng BJ, Yuen KY. Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome. Virology. 2007 Oct 25; 367(2):428-39. PMID: 17617433.
      Citations: 77     Fields:    Translation:AnimalsCells
    196. Du L, Kao RY, Zhou Y, He Y, Zhao G, Wong C, Jiang S, Yuen KY, Jin DY, Zheng BJ. Cleavage of spike protein of SARS coronavirus by protease factor Xa is associated with viral infectivity. Biochem Biophys Res Commun. 2007 Jul 20; 359(1):174-9. PMID: 17533109.
      Citations: 44     Fields:    Translation:HumansCells
    197. Wong S, Lau S, Woo P, Yuen KY. Bats as a continuing source of emerging infections in humans. Rev Med Virol. 2007 Mar-Apr; 17(2):67-91. PMID: 17042030.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    198. Woo PC, Wang M, Lau SK, Xu H, Poon RW, Guo R, Wong BH, Gao K, Tsoi HW, Huang Y, Li KS, Lam CS, Chan KH, Zheng BJ, Yuen KY. Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features. J Virol. 2007 Feb; 81(4):1574-85. PMID: 17121802.
      Citations: 123     Fields:    Translation:AnimalsCells
    199. Woo PC, Lau SK, Yuen KY. Infectious diseases emerging from Chinese wet-markets: zoonotic origins of severe respiratory viral infections. Curr Opin Infect Dis. 2006 Oct; 19(5):401-7. PMID: 16940861.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    200. Chu DKW, Poon LLM, Chan KH, Chan KH, Chen H, Chen H, Guan Y, Guan Y, Yuen KY, Peiris JSM. Coronaviruses in bent-winged bats (Miniopterus spp.). J Gen Virol. 2006 Sep; 87(Pt 9):2461-2466. PMID: 16894183.
      Citations: 36     Fields:    Translation:AnimalsCells
    201. Chan CP, Siu KL, Chin KT, Yuen KY, Zheng B, Jin DY. Modulation of the unfolded protein response by the severe acute respiratory syndrome coronavirus spike protein. J Virol. 2006 Sep; 80(18):9279-87. PMID: 16940539.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    202. Woo PC, Lau SK, Yip CC, Huang Y, Tsoi HW, Chan KH, Yuen KY. Comparative analysis of 22 coronavirus HKU1 genomes reveals a novel genotype and evidence of natural recombination in coronavirus HKU1. J Virol. 2006 Jul; 80(14):7136-45. PMID: 16809319.
      Citations: 85     Fields:    Translation:HumansCells
    203. Du L, He Y, Wang Y, Wang Y, Zhang H, Ma S, Wong CK, Wu SH, Ng F, Huang JD, Yuen KY, Jiang S, Zhou Y, Zheng BJ. Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines. Virology. 2006 Sep 15; 353(1):6-16. PMID: 16793110.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    204. Lau SK, Woo PC, Yip CC, Tse H, Tsoi HW, Cheng VC, Lee P, Tang BS, Cheung CH, Lee RA, So LY, Lau YL, Chan KH, Yuen KY. Coronavirus HKU1 and other coronavirus infections in Hong Kong. J Clin Microbiol. 2006 Jun; 44(6):2063-71. PMID: 16757599.
      Citations: 144     Fields:    Translation:HumansCells
    205. Che XY, Di B, Zhao GP, Wang YD, Qiu LW, Hao W, Wang M, Qin PZ, Liu YF, Chan KH, Cheng VC, Yuen KY. A patient with asymptomatic severe acute respiratory syndrome (SARS) and antigenemia from the 2003-2004 community outbreak of SARS in Guangzhou, China. Clin Infect Dis. 2006 Jul 01; 43(1):e1-5. PMID: 16758408.
      Citations: 17     Fields:    Translation:HumansAnimalsPHPublic Health
    206. Woo PC, Lau SK, Li KS, Poon RW, Wong BH, Tsoi HW, Yip BC, Huang Y, Chan KH, Yuen KY. Molecular diversity of coronaviruses in bats. Virology. 2006 Jul 20; 351(1):180-7. PMID: 16647731.
      Citations: 133     Fields:    Translation:AnimalsCells
    207. Zhang L, Zhang F, Yu W, He T, Yu J, Yi CE, Ba L, Li W, Farzan M, Chen Z, Yuen KY, Ho D. Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals. J Med Virol. 2006 Jan; 78(1):1-8. PMID: 16299724.
      Citations: 80     Fields:    Translation:HumansCells
    208. Wong SS, Yuen KY. Nasopharyngeal detection of severe acute respiratory syndrome-associated coronavirus RNA in health-care workers. Chest. 2006 Jan; 129(1):12-3. PMID: 16424407.
      Citations: 1     Fields:    Translation:HumansCells
    209. Chan KH, Cheng VC, Woo PC, Lau SK, Poon LL, Guan Y, Seto WH, Yuen KY, Peiris JS. Serological responses in patients with severe acute respiratory syndrome coronavirus infection and cross-reactivity with human coronaviruses 229E, OC43, and NL63. Clin Diagn Lab Immunol. 2005 Nov; 12(11):1317-21. PMID: 16275947.
      Citations: 40     Fields:    Translation:HumansCells
    210. Woo PC, Lau SK, Tsoi HW, Huang Y, Poon RW, Chu CM, Lee RA, Luk WK, Wong GK, Wong BH, Cheng VC, Tang BS, Wu AK, Yung RW, Chen H, Guan Y, Chan KH, Yuen KY. Clinical and molecular epidemiological features of coronavirus HKU1-associated community-acquired pneumonia. J Infect Dis. 2005 Dec 01; 192(11):1898-907. PMID: 16267760.
      Citations: 103     Fields:    Translation:HumansCells
    211. Woo PC, Lau SK, Tsoi HW, Chen ZW, Wong BH, Zhang L, Chan JK, Wong LP, He W, Ma C, Chan KH, Ho DD, Yuen KY. SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus. Vaccine. 2005 Oct 10; 23(42):4959-68. PMID: 15993989.
      Citations: 18     Fields:    Translation:AnimalsCells
    212. Wong SS, Yuen KY. The severe acute respiratory syndrome (SARS). J Neurovirol. 2005 Oct; 11(5):455-68. PMID: 16287687.
      Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    213. Lau SK, Woo PC, Li KS, Huang Y, Tsoi HW, Wong BH, Wong SS, Leung SY, Chan KH, Yuen KY. Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):14040-5. PMID: 16169905.
      Citations: 513     Fields:    Translation:AnimalsCells
    214. Yang H, Xie W, Xue X, Yang K, Ma J, Liang W, Zhao Q, Zhou Z, Pei D, Ziebuhr J, Hilgenfeld R, Yuen KY, Wong L, Gao G, Chen S, Chen Z, Ma D, Bartlam M, Rao Z. Design of wide-spectrum inhibitors targeting coronavirus main proteases. PLoS Biol. 2005 Oct; 3(10):e324. PMID: 16128623.
      Citations: 146     Fields:    Translation:HumansAnimalsCells
    215. Mei YB, Liao ZY, Wang YD, Zhang LY, Xu H, Yuen KY, Che XY. [Cloning, purification, and antigenic characterization of three recombinant fragments derived from SARS-CoV S1 domain]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2005 Sep; 19(3):275-8. PMID: 16261215.
      Citations:    Fields:    Translation:HumansCells
    216. Woo PC, Lau SK, Wong BH, Tsoi HW, Fung AM, Kao RY, Chan KH, Peiris JS, Yuen KY. Differential sensitivities of severe acute respiratory syndrome (SARS) coronavirus spike polypeptide enzyme-linked immunosorbent assay (ELISA) and SARS coronavirus nucleocapsid protein ELISA for serodiagnosis of SARS coronavirus pneumonia. J Clin Microbiol. 2005 Jul; 43(7):3054-8. PMID: 16000415.
      Citations: 40     Fields:    Translation:HumansCells
    217. Lau SK, Che XY, Woo PC, Wong BH, Cheng VC, Woo GK, Hung IF, Poon RW, Chan KH, Peiris JS, Yuen KY. SARS coronavirus detection methods. Emerg Infect Dis. 2005 Jul; 11(7):1108-11. PMID: 16022791.
      Citations: 15     Fields:    Translation:HumansCells
    218. Woo PC, Lau SK, Huang Y, Tsoi HW, Chan KH, Yuen KY. Phylogenetic and recombination analysis of coronavirus HKU1, a novel coronavirus from patients with pneumonia. Arch Virol. 2005 Nov; 150(11):2299-311. PMID: 15986174.
      Citations: 19     Fields:    Translation:HumansCells
    219. Cheung CY, Poon LL, Ng IH, Ng IH, Luk W, Sia SF, Wu MH, Chan KH, Yuen KY, Gordon S, Guan Y, Peiris JS. Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis. J Virol. 2005 Jun; 79(12):7819-26. PMID: 15919935.
      Citations: 148     Fields:    Translation:HumansAnimalsCells
    220. Che XY, Qiu LW, Liao ZY, Wang YD, Wen K, Pan YX, Hao W, Mei YB, Cheng VC, Yuen KY. Antigenic cross-reactivity between severe acute respiratory syndrome-associated coronavirus and human coronaviruses 229E and OC43. J Infect Dis. 2005 Jun 15; 191(12):2033-7. PMID: 15897988.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    221. Tang BS, Chan KH, Cheng VC, Woo PC, Lau SK, Lam CC, Chan TL, Chan TL, Wu AK, Hung IF, Leung SY, Yuen KY. Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by severe acute respiratory syndrome coronavirus and human coronavirus 229E. J Virol. 2005 May; 79(10):6180-93. PMID: 15858003.
      Citations: 33     Fields:    Translation:HumansCells
    222. Nal B, Chan C, Kien F, Siu L, Tse J, Chu K, Kam J, Staropoli I, Crescenzo-Chaigne B, Escriou N, van der Werf S, Yuen KY, Altmeyer R. Differential maturation and subcellular localization of severe acute respiratory syndrome coronavirus surface proteins S, M and E. J Gen Virol. 2005 May; 86(Pt 5):1423-1434. PMID: 15831954.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    223. Yam WC, Chan KH, Chow KH, Poon LL, Lam HY, Yuen KY, Seto WH, Peiris JS. Clinical evaluation of real-time PCR assays for rapid diagnosis of SARS coronavirus during outbreak and post-epidemic periods. J Clin Virol. 2005 May; 33(1):19-24. PMID: 15797361.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    224. Chen Z, Zhang L, Qin C, Ba L, Yi CE, Zhang F, Wei Q, He T, Yu W, Yu J, Gao H, Tu X, Gettie A, Farzan M, Yuen KY, Ho DD. Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region. J Virol. 2005 Mar; 79(5):2678-88. PMID: 15708987.
      Citations: 79     Fields:    Translation:AnimalsCells
    225. Poon LL, Chu DK, Chan KH, Wong OK, Ellis TM, Leung YH, Lau SK, Woo PC, Suen KY, Yuen KY, Guan Y, Peiris JS. Identification of a novel coronavirus in bats. J Virol. 2005 Feb; 79(4):2001-9. PMID: 15681402.
      Citations: 143     Fields:    Translation:AnimalsCells
    226. Woo PC, Lau SK, Chu CM, Chan KH, Tsoi HW, Huang Y, Wong BH, Poon RW, Cai JJ, Cai JJ, Luk WK, Poon LL, Wong SS, Guan Y, Peiris JS, Yuen KY. Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia. J Virol. 2005 Jan; 79(2):884-95. PMID: 15613317.
      Citations: 478     Fields:    Translation:HumansCells
    227. Chu CM, Leung WS, Cheng VC, Chan KH, Chan KH, Lin AW, Chan VL, Lam JY, Chan KS, Yuen KY. Duration of RT-PCR positivity in severe acute respiratory syndrome. Eur Respir J. 2005 Jan; 25(1):12-4. PMID: 15640317.
      Citations: 10     Fields:    Translation:HumansCells
    228. Woo PC, Huang Y, Lau SK, Tsoi HW, Yuen KY. In silico analysis of ORF1ab in coronavirus HKU1 genome reveals a unique putative cleavage site of coronavirus HKU1 3C-like protease. Microbiol Immunol. 2005; 49(10):899-908. PMID: 16237267.
      Citations: 17     Fields:    Translation:Cells
    229. Zheng BJ, Guan Y, Hez ML, Sun H, Du L, Zheng Y, Wong KL, Chen H, Chen Y, Lu L, Tanner JA, Watt RM, Niccolai N, Bernini A, Spiga O, Woo PC, Kung HF, Yuen KY, Huang JD. Synthetic peptides outside the spike protein heptad repeat regions as potent inhibitors of SARS-associated coronavirus. Antivir Ther. 2005; 10(3):393-403. PMID: 15918330.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    230. Peiris JS, Guan Y, Yuen KY. Severe acute respiratory syndrome. Nat Med. 2004 Dec; 10(12 Suppl):S88-97. PMID: 15577937.
      Citations: 350     Fields:    Translation:HumansAnimalsPHPublic Health
    231. Woo PC, Lau SK, Wong BH, Chan KH, Hui WT, Kwan GS, Kwan GS, Peiris JS, Couch RB, Yuen KY. False-positive results in a recombinant severe acute respiratory syndrome-associated coronavirus (SARS-CoV) nucleocapsid enzyme-linked immunosorbent assay due to HCoV-OC43 and HCoV-229E rectified by Western blotting with recombinant SARS-CoV spike polypeptide. J Clin Microbiol. 2004 Dec; 42(12):5885-8. PMID: 15583332.
      Citations: 39     Fields:    Translation:HumansCells
    232. Chu CM, Poon LL, Cheng VC, Chan KS, Hung IF, Wong MM, Chan KH, Leung WS, Tang BS, Chan VL, Ng WL, Ng WL, Sim TC, Ng PW, Law KI, Tse DM, Peiris JS, Yuen KY. Initial viral load and the outcomes of SARS. CMAJ. 2004 Nov 23; 171(11):1349-52. PMID: 15557587.
      Citations: 57     Fields:    Translation:HumansCells
    233. Che XY, Hao W, Wang Y, Di B, Yin K, Xu YC, Feng CS, Wan ZY, Wan ZY, Cheng VC, Yuen KY. Nucleocapsid protein as early diagnostic marker for SARS. Emerg Infect Dis. 2004 Nov; 10(11):1947-9. PMID: 15550204.
      Citations: 27     Fields:    Translation:HumansCells
    234. Poon LL, Guan Y, Nicholls JM, Yuen KY, Peiris JS. The aetiology, origins, and diagnosis of severe acute respiratory syndrome. Lancet Infect Dis. 2004 Nov; 4(11):663-71. PMID: 15522678.
      Citations: 56     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    235. Cheng VC, Tang BS, Wu AK, Chu CM, Yuen KY. Medical treatment of viral pneumonia including SARS in immunocompetent adult. J Infect. 2004 Nov; 49(4):262-73. PMID: 15474623.
      Citations: 34     Fields:    Translation:Humans
    236. Kao RY, To AP, Ng LW, Tsui WH, Lee TS, Tsoi HW, Yuen KY. Characterization of SARS-CoV main protease and identification of biologically active small molecule inhibitors using a continuous fluorescence-based assay. FEBS Lett. 2004 Oct 22; 576(3):325-30. PMID: 15498556.
      Citations: 14     Fields:    Translation:Cells
    237. Kao RY, Tsui WH, Lee TS, Tanner JA, Watt RM, Huang JD, Hu L, Chen G, Chen Z, Zhang L, He T, Chan KH, Tse H, To AP, Ng LW, Wong BC, Tsoi HW, Yang D, Ho DD, Yuen KY. Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics. Chem Biol. 2004 Sep; 11(9):1293-9. PMID: 15380189.
      Citations: 59     Fields:    Translation:AnimalsCells
    238. Hung IF, Cheng VC, Wu AK, Tang BS, Chan KH, Chan KH, Chu CM, Wong MM, Hui WT, Poon LL, Tse DM, Chan KS, Woo PC, Lau SK, Peiris JS, Yuen KY. Viral loads in clinical specimens and SARS manifestations. Emerg Infect Dis. 2004 Sep; 10(9):1550-7. PMID: 15498155.
      Citations: 89     Fields:    Translation:HumansCellsPHPublic Health
    239. Chen F, Chen F, Chan KH, Chan KH, Jiang Y, Jiang Y, Kao RY, Lu HT, Fan KW, Cheng VC, Tsui WH, Hung IF, Lee TS, Guan Y, Guan Y, Peiris JS, Yuen KY. In vitro susceptibility of 10 clinical isolates of SARS coronavirus to selected antiviral compounds. J Clin Virol. 2004 Sep; 31(1):69-75. PMID: 15288617.
      Citations: 152     Fields:    Translation:HumansCells
    240. Lau SK, Woo PC, Wong BH, Tsoi HW, Woo GK, Poon RW, Chan KH, Wei WI, Peiris JS, Yuen KY. Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in sars patients by enzyme-linked immunosorbent assay. J Clin Microbiol. 2004 Jul; 42(7):2884-9. PMID: 15243033.
      Citations: 48     Fields:    Translation:HumansCells
    241. Woo PC, Lau SK, Wong BH, Chan KH, Chu CM, Tsoi HW, Huang Y, Peiris JS, Yuen KY. Longitudinal profile of immunoglobulin G (IgG), IgM, and IgA antibodies against the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in patients with pneumonia due to the SARS coronavirus. Clin Diagn Lab Immunol. 2004 Jul; 11(4):665-8. PMID: 15242938.
      Citations: 52     Fields:    Translation:HumansCells
    242. Poon LL, Wong BW, Chan KH, Leung CS, Leung CS, Yuen KY, Guan Y, Peiris JS. A one step quantitative RT-PCR for detection of SARS coronavirus with an internal control for PCR inhibitors. J Clin Virol. 2004 Jul; 30(3):214-7. PMID: 15135737.
      Citations: 15     Fields:    Translation:HumansCells
    243. Che XY, Qiu LW, Pan YX, Wen K, Hao W, Zhang LY, Wang YD, Liao ZY, Hua X, Cheng VC, Yuen KY. Sensitive and specific monoclonal antibody-based capture enzyme immunoassay for detection of nucleocapsid antigen in sera from patients with severe acute respiratory syndrome. J Clin Microbiol. 2004 Jun; 42(6):2629-35. PMID: 15184444.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    244. Hui RK, Zeng F, Chan CM, Yuen KY, Peiris JS, Leung FC. Reverse transcriptase PCR diagnostic assay for the coronavirus associated with severe acute respiratory syndrome. J Clin Microbiol. 2004 May; 42(5):1994-9. PMID: 15131160.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    245. Woo PC, Lau SK, Wong BH, Tsoi HW, Fung AM, Chan KH, Tam VK, Peiris JS, Yuen KY. Detection of specific antibodies to severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein for serodiagnosis of SARS coronavirus pneumonia. J Clin Microbiol. 2004 May; 42(5):2306-9. PMID: 15131220.
      Citations: 45     Fields:    Translation:HumansCells
    246. Sung JJ, Wu A, Joynt GM, Yuen KY, Lee N, Chan PK, Cockram CS, Ahuja AT, Yu LM, Wong VW, Hui DS. Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak. Thorax. 2004 May; 59(5):414-20. PMID: 15115870.
      Citations: 69     Fields:    Translation:HumansPHPublic Health
    247. Poon LL, Leung CS, Leung CS, Tashiro M, Chan KH, Wong BW, Yuen KY, Guan Y, Peiris JS. Rapid detection of the severe acute respiratory syndrome (SARS) coronavirus by a loop-mediated isothermal amplification assay. Clin Chem. 2004 Jun; 50(6):1050-2. PMID: 15054079.
      Citations: 36     Fields:    Translation:HumansCells
    248. Wong AT, Tsang OT, Wong MY, Lim WL, Zheng BJ, Lee SS, Lai ST, Yuen KY, Choi KW, Tso EY, Chau TN, Tong WL, Chiu MC, Yu WC. Coronavirus infection in an AIDS patient. AIDS. 2004 Mar 26; 18(5):829-30. PMID: 15075525.
      Citations: 7     Fields:    Translation:HumansCells
    249. Woo PC, Lau SK, Tsoi HW, Chan KH, Wong BH, Che XY, Tam VK, Tam SC, Cheng VC, Hung IF, Wong SS, Zheng BJ, Guan Y, Yuen KY. Relative rates of non-pneumonic SARS coronavirus infection and SARS coronavirus pneumonia. Lancet. 2004 Mar 13; 363(9412):841-5. PMID: 15031027.
      Citations: 66     Fields:    Translation:HumansCells
    250. Chu CM, Cheng VC, Hung IF, Wong MM, Chan KH, Chan KH, Chan KS, Kao RY, Poon LL, Wong CL, Guan Y, Peiris JS, Yuen KY. Role of lopinavir/ritonavir in the treatment of SARS: initial virological and clinical findings. Thorax. 2004 Mar; 59(3):252-6. PMID: 14985565.
      Citations: 531     Fields:    Translation:HumansCTClinical Trials
    251. Cheng VC, Hung IF, Tang BS, Chu CM, Wong MM, Chan KH, Chan KH, Wu AK, Tse DM, Chan KS, Zheng BJ, Peiris JS, Sung JJ, Yuen KY. Viral replication in the nasopharynx is associated with diarrhea in patients with severe acute respiratory syndrome. Clin Infect Dis. 2004 Feb 15; 38(4):467-75. PMID: 14765337.
      Citations: 33     Fields:    Translation:HumansCellsPHPublic Health
    252. Guan Y, Guan Y, Peiris JS, Zheng B, Zheng B, Poon LL, Chan KH, Chan KH, Zeng FY, Chan CW, Chan MN, Chen JD, Chen JD, Chow KY, Hon CC, Hui KH, Li J, Li J, Li VY, Wang Y, Wang Y, Leung SW, Yuen KY, Leung FC. Molecular epidemiology of the novel coronavirus that causes severe acute respiratory syndrome. Lancet. 2004 Jan 10; 363(9403):99-104. PMID: 14726162.
      Citations: 37     Fields:    Translation:HumansCellsPHPublic Health
    253. Wen K, Mei YB, Qiu LW, Liao ZY, Yuen KY, Che XY. Preparation and characterization of monoclonal antibodies against S1 domain at N-terminal residues 249 to 667 of SARS-associated coronavirus S1 protein. Di Yi Jun Yi Da Xue Xue Bao. 2004 Jan; 24(1):1-6. PMID: 14724082.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    254. Poon LL, Chan KH, Wong OK, Cheung TK, Ng I, Ng I, Zheng B, Seto WH, Yuen KY, Guan Y, Guan Y, Peiris JS. Detection of SARS coronavirus in patients with severe acute respiratory syndrome by conventional and real-time quantitative reverse transcription-PCR assays. Clin Chem. 2004 Jan; 50(1):67-72. PMID: 14709637.
      Citations: 42     Fields:    Translation:HumansCells
    255. Poon LL, Chan KH, Wong OK, Yam WC, Yuen KY, Guan Y, Lo YM, Peiris JS. Early diagnosis of SARS coronavirus infection by real time RT-PCR. J Clin Virol. 2003 Dec; 28(3):233-8. PMID: 14522060.
      Citations: 66     Fields:    Translation:HumansCells
    256. Chim SS, Tsui SK, Chan KC, Au TC, Hung EC, Tong YK, Chiu RW, Ng EK, Chan PK, Chu CM, Sung JJ, Tam JS, Fung KP, Waye MM, Lee CY, Yuen KY, Lo YM. Genomic characterisation of the severe acute respiratory syndrome coronavirus of Amoy Gardens outbreak in Hong Kong. Lancet. 2003 Nov 29; 362(9398):1807-8. PMID: 14654320.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic Health
    257. Zhong NS, Zheng BJ, Li YM, Xie ZH, Chan KH, Li PH, Tan SY, Chang Q, Xie JP, Liu XQ, Xu J, Li DX, Yuen KY, Guan Y. Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003. Lancet. 2003 Oct 25; 362(9393):1353-8. PMID: 14585636.
      Citations: 336     Fields:    Translation:HumansCellsPHPublic Health
    258. Yam WC, Chan KH, Poon LL, Guan Y, Yuen KY, Seto WH, Peiris JS. Evaluation of reverse transcription-PCR assays for rapid diagnosis of severe acute respiratory syndrome associated with a novel coronavirus. J Clin Microbiol. 2003 Oct; 41(10):4521-4. PMID: 14532176.
      Citations: 66     Fields:    Translation:HumansCells
    259. Guan Y, Guan Y, Zheng BJ, He YQ, Liu XL, Zhuang ZX, Cheung CL, Cheung CL, Luo SW, Li PH, Zhang LJ, Guan YJ, Butt KM, Wong KL, Chan KW, Lim W, Shortridge KF, Yuen KY, Peiris JS, Poon LL. Isolation and characterization of viruses related to the SARS coronavirus from animals in southern China. Science. 2003 Oct 10; 302(5643):276-8. PMID: 12958366.
      Citations: 688     Fields:    Translation:HumansAnimalsCells
    260. Zeng FY, Chan CW, Chan MN, Chen JD, Chow KY, Hon CC, Hui KH, Li J, Li VY, Wang CY, Wang PY, Guan Y, Zheng B, Poon LL, Chan KH, Yuen KY, Peiris JS, Leung FC. The complete genome sequence of severe acute respiratory syndrome coronavirus strain HKU-39849 (HK-39). Exp Biol Med (Maywood). 2003 Jul; 228(7):866-73. PMID: 12876307.
      Citations: 23     Fields:    Translation:Cells
    261. Poon LL, Wong OK, Chan KH, Luk W, Yuen KY, Peiris JS, Guan Y, Guan Y. Rapid diagnosis of a coronavirus associated with severe acute respiratory syndrome (SARS). Clin Chem. 2003 Jun; 49(6 Pt 1):953-5. PMID: 12765993.
      Citations: 48     Fields:    Translation:HumansCells
    262. Peiris JS, Chu CM, Chu CM, Cheng VC, Chan KS, Chan KS, Chan KS, Hung IF, Poon LL, Law KI, Tang BS, Hon TY, Hon TY, Chan CS, Chan CS, Chan KH, Ng JS, Zheng BJ, Ng WL, Ng WL, Lai RW, Lai RW, Guan Y, Guan Y, Yuen KY. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003 May 24; 361(9371):1767-72. PMID: 12781535.
      Citations: 793     Fields:    Translation:HumansCellsPHPublic Health
    263. Peiris JS, Lai ST, Poon LL, Guan Y, Yam LY, Lim W, Nicholls J, Yee WK, Yan WW, Cheung MT, Cheng VC, Chan KH, Tsang DN, Yung RW, Ng TK, Yuen KY. Coronavirus as a possible cause of severe acute respiratory syndrome. Lancet. 2003 Apr 19; 361(9366):1319-25. PMID: 12711465.
      Citations: 898     Fields:    Translation:HumansCells
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