Stanley Perlman

InstitutionUNIVERSITY OF IOWA
AddressIowa City
Iowa
United States
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    Publication Timeline
    COVID-19 publications
    Bar chart showing 28 Covid-19 publications, with a maximum of 4 publications in October 2020
    All Publications
    Bar chart showing 218 publications over 31 distinct years, with a maximum of 26 publications in 2020
    These graphs show COVID-19 publications by month since August 2019 and all publications written by authors of COVID-19 publications over the past 30 years.

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    Publication Field Summary
    This graph shows the number and percent of publications by field. Fields are based on how the National Library of Medicine (NLM) classifies the publications' journals and might not represent the specific topics of the publications. Note that an individual publication can be assigned to more than one field. As a result, the publication counts in this graph might add up to more than the number of publications the person has written. To see the data as text, click here.
    Publication List
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zheng J, Wang Y, Li K, Meyerholz DK, Allamargot C, Perlman S. Severe Acute Respiratory Syndrome Coronavirus 2-Induced Immune Activation and Death of Monocyte-Derived Human Macrophages and Dendritic Cells. J Infect Dis. 2021 03 03; 223(5):785-795. PMID: 33277988.
      Citations: 2     Fields:    Translation:HumansCells
    2. Munoz FM, Cramer JP, Dekker CL, Dudley MZ, Graham BS, Gurwith M, Law B, Perlman S, Polack FP, Spergel JM, Van Braeckel E, Ward BJ, Didierlaurent AM, Lambert PH. Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data. Vaccine. 2021 Feb 23. PMID: 33637387.
      Citations:    Fields:    
    3. Meyerholz DK, Perlman S. Does common cold coronavirus infection protect against severe SARS-CoV-2 disease? J Clin Invest. 2021 01 04; 131(1). PMID: 33216734.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    4. Channappanavar R, Perlman S. Age-related susceptibility to coronavirus infections: role of impaired and dysregulated host immunity. J Clin Invest. 2020 12 01; 130(12):6204-6213. PMID: 33085654.
      Citations: 5     Fields:    Translation:HumansAnimals
    5. Zheng J, Wong LR, Li K, Verma AK, Ortiz ME, Wohlford-Lenane C, Leidinger MR, Knudson CM, Meyerholz DK, McCray PB, Perlman S. COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice. Nature. 2021 01; 589(7843):603-607. PMID: 33166988.
      Citations: 11     Fields:    Translation:HumansAnimals
    6. Wong LR, Li K, Sun J, Zhuang Z, Zhao J, McCray PB, Perlman S. Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2. STAR Protoc. 2020 Dec 18; 1(3):100169. PMID: 33377063.
      Citations:    
    7. Ghosh S, Dellibovi-Ragheb TA, Kerviel A, Pak E, Qiu Q, Fisher M, Takvorian PM, Bleck C, Hsu VW, Fehr AR, Perlman S, Achar SR, Straus MR, Whittaker GR, de Haan CAM, Kehrl J, Altan-Bonnet G, Altan-Bonnet N. ß-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway. Cell. 2020 12 10; 183(6):1520-1535.e14. PMID: 33157038.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    8. Heer CD, Sanderson DJ, Voth LS, Alhammad YMO, Schmidt MS, Trammell SAJ, Perlman S, Cohen MS, Fehr AR, Brenner C. Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity. J Biol Chem. 2020 12 25; 295(52):17986-17996. PMID: 33051211.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    9. Perlman S, Zumla A. MERS-CoV in Africa-an enigma with relevance to COVID-19. Lancet Infect Dis. 2021 03; 21(3):303-305. PMID: 33035475.
      Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
    10. Wang Y, Zhang L, Sang L, Ye F, Ruan S, Zhong B, Song T, Alshukairi AN, Chen R, Zhang Z, Gan M, Zhu A, Huang Y, Luo L, Mok CKP, Mok CKP, Al Gethamy MM, Tan H, Li Z, Huang X, Li F, Sun J, Zhang Y, Wen L, Li Y, Chen Z, Zhuang Z, Zhuo J, Chen C, Kuang L, Wang J, Lv H, Jiang Y, Li M, Lin Y, Deng Y, Tang L, Liang J, Huang J, Perlman S, Zhong N, Zhao J, Malik Peiris JS, Li Y, Zhao J. Kinetics of viral load and antibody response in relation to COVID-19 severity. J Clin Invest. 2020 10 01; 130(10):5235-5244. PMID: 32634129.
      Citations: 65     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    11. Muñoz-Fontela C, Dowling WE, Funnell SGP, Funnell SGP, Gsell PS, Riveros-Balta AX, Albrecht RA, Andersen H, Baric RS, Carroll MW, Cavaleri M, Qin C, Crozier I, Dallmeier K, de Waal L, de Wit E, Delang L, Dohm E, Duprex WP, Falzarano D, Finch CL, Frieman MB, Graham BS, Gralinski LE, Guilfoyle K, Haagmans BL, Hamilton GA, Hartman AL, Herfst S, Kaptein SJF, Klimstra WB, Knezevic I, Krause PR, Kuhn JH, Le Grand R, Lewis MG, Liu WC, Maisonnasse P, McElroy AK, Munster V, Oreshkova N, Rasmussen AL, Rocha-Pereira J, Rockx B, Rodríguez E, Rogers TF, Salguero FJ, Schotsaert M, Stittelaar KJ, Thibaut HJ, Tseng CT, Vergara-Alert J, Beer M, Brasel T, Chan JFW, García-Sastre A, Neyts J, Perlman S, Reed DS, Richt JA, Roy CJ, et al. Animal models for COVID-19. Nature. 2020 10; 586(7830):509-515. PMID: 32967005.
      Citations: 40     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    12. Sariol A, Mackin S, Allred MG, Ma C, Zhou Y, Zhang Q, Zou X, Abrahante JE, Meyerholz DK, Perlman S. Microglia depletion exacerbates demyelination and impairs remyelination in a neurotropic coronavirus infection. Proc Natl Acad Sci U S A. 2020 09 29; 117(39):24464-24474. PMID: 32929007.
      Citations: 1     Fields:    Translation:AnimalsCells
    13. Welch JL, Xiang J, Mackin SR, Perlman S, Thorne P, O'Shaughnessy P, Strzelecki B, Aubin P, Ortiz-Hernandez M, Stapleton JT. Inactivation of Severe Acute Respiratory Coronavirus Virus 2 (SARS-CoV-2) and Diverse RNA and DNA Viruses on Three-Dimensionally Printed Surgical Mask Materials. Infect Control Hosp Epidemiol. 2021 03; 42(3):253-260. PMID: 32783787.
      Citations: 1     Fields:    
    14. Rathnayake AD, Zheng J, Kim Y, Perera KD, Mackin S, Meyerholz DK, Kashipathy MM, Battaile KP, Lovell S, Perlman S, Groutas WC, Chang KO. 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med. 2020 08 19; 12(557). PMID: 32747425.
      Citations: 18     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    15. Perlman S. COVID-19 poses a riddle for the immune system. Nature. 2020 08; 584(7821):345-346. PMID: 32807916.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    16. Sariol A, Perlman S. Lessons for COVID-19 Immunity from Other Coronavirus Infections. Immunity. 2020 08 18; 53(2):248-263. PMID: 32717182.
      Citations: 34     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    17. Pan R, Zhang Q, Anthony SM, Zhou Y, Zou X, Cassell M, Perlman S. Oligodendrocytes that survive acute coronavirus infection induce prolonged inflammatory responses in the CNS. Proc Natl Acad Sci U S A. 2020 07 07; 117(27):15902-15910. PMID: 32571951.
      Citations: 4     Fields:    Translation:AnimalsCells
    18. Sun J, Zhuang Z, Zheng J, Li K, Wong RL, Liu D, Huang J, He J, Zhu A, Zhao J, Li X, Xi Y, Chen R, Alshukairi AN, Chen Z, Zhang Z, Chen C, Huang X, Li F, Lai X, Chen D, Wen L, Zhuo J, Zhang Y, Wang Y, Huang S, Dai J, Shi Y, Zheng K, Leidinger MR, Chen J, Li Y, Zhong N, Meyerholz DK, McCray PB, Perlman S, Zhao J. Generation of a Broadly Useful Model for COVID-19 Pathogenesis, Vaccination, and Treatment. Cell. 2020 08 06; 182(3):734-743.e5. PMID: 32643603.
      Citations: 68     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    19. Hassan AO, Case JB, Winkler ES, Thackray LB, Kafai NM, Bailey AL, McCune BT, Fox JM, Chen RE, Alsoussi WB, Turner JS, Schmitz AJ, Lei T, Shrihari S, Keeler SP, Fremont DH, Greco S, McCray PB, Perlman S, Holtzman MJ, Ellebedy AH, Diamond MS. A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies. Cell. 2020 08 06; 182(3):744-753.e4. PMID: 32553273.
      Citations: 101     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    20. Lambert PH, Lambert PH, Ambrosino DM, Andersen SR, Baric RS, Black SB, Chen RT, Dekker CL, Didierlaurent AM, Graham BS, Martin SD, Molrine DC, Perlman S, Picard-Fraser PA, Pollard AJ, Qin C, Subbarao K, Cramer JP. Consensus summary report for CEPI/BC March 12-13, 2020 meeting: Assessment of risk of disease enhancement with COVID-19 vaccines. Vaccine. 2020 06 26; 38(31):4783-4791. PMID: 32507409.
      Citations: 23     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    21. Lipsitch M, Perlman S, Waldor MK. Testing COVID-19 therapies to prevent progression of mild disease. Lancet Infect Dis. 2020 12; 20(12):1367. PMID: 32618282.
      Citations: 2     Fields:    Translation:HumansCellsPHPublic Health
    22. Li K, Li Z, Wohlford-Lenane C, Meyerholz DK, Channappanavar R, An D, Perlman S, McCray PB, He B. Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection. mBio. 2020 04 07; 11(2). PMID: 32265331.
      Citations: 13     Fields:    Translation:AnimalsCellsPHPublic Health
    23. Memish ZA, Perlman S, Van Kerkhove MD, Zumla A. Middle East respiratory syndrome. Lancet. 2020 03 28; 395(10229):1063-1077. PMID: 32145185.
      Citations: 88     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    24. Calisher C, Carroll D, Colwell R, Colwell R, Corley RB, Daszak P, Drosten C, Enjuanes L, Farrar J, Field H, Golding J, Gorbalenya A, Haagmans B, Hughes JM, Karesh WB, Keusch GT, Lam SK, Lubroth J, Mackenzie JS, Madoff L, Madoff L, Mazet J, Mazet J, Palese P, Perlman S, Poon L, Roizman B, Saif L, Subbarao K, Turner M. Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19. Lancet. 2020 03 07; 395(10226):e42-e43. PMID: 32087122.
      Citations: 45     Fields:    Translation:HumansCellsPHPublic Health
    25. Qing E, Hantak M, Perlman S, Gallagher T. Distinct Roles for Sialoside and Protein Receptors in Coronavirus Infection. mBio. 2020 02 11; 11(1). PMID: 32047128.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    26. Perlman S. Another Decade, Another Coronavirus. N Engl J Med. 2020 02 20; 382(8):760-762. PMID: 31978944.
      Citations: 187     Fields:    Translation:HumansCells
    27. Grunewald ME, Shaban MG, Mackin SR, Fehr AR, Perlman S. Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression. J Virol. 2020 01 17; 94(3). PMID: 31694960.
      Citations: 16     Fields:    Translation:AnimalsCells
    28. Channappanavar R, Perlman S. Evaluation of Activation and Inflammatory Activity of Myeloid Cells During Pathogenic Human Coronavirus Infection. Methods Mol Biol. 2020; 2099:195-204. PMID: 31883097.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    29. Wang Y, Grunewald M, Perlman S. Coronaviruses: An Updated Overview of Their Replication and Pathogenesis. Methods Mol Biol. 2020; 2203:1-29. PMID: 32833200.
      Citations: 9     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    30. Zheng J, Hassan S, Alagaili AN, Alshukairi AN, Amor NMS, Mukhtar N, Nazeer IM, Tahir Z, Akhter N, Perlman S, Yaqub T. Middle East Respiratory Syndrome Coronavirus Seropositivity in Camel Handlers and Their Families, Pakistan. Emerg Infect Dis. 2019 12; 25(12). PMID: 31742530.
      Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    31. Zumla A, Memish ZA, Hui DS, Perlman S. Vaccine against Middle East respiratory syndrome coronavirus. Lancet Infect Dis. 2019 10; 19(10):1054-1055. PMID: 31559955.
      Citations: 6     Fields:    Translation:HumansCells
    32. Channappanavar R, Fehr AR, Zheng J, Wohlford-Lenane C, Abrahante JE, Mack M, Sompallae R, McCray PB, Meyerholz DK, Perlman S. IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes. J Clin Invest. 2019 07 29; 129(9):3625-3639. PMID: 31355779.
      Citations: 135     Fields:    Translation:HumansAnimalsCells
    33. Grunewald ME, Chen Y, Kuny C, Maejima T, Lease R, Ferraris D, Aikawa M, Sullivan CS, Perlman S, Fehr AR. The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression. PLoS Pathog. 2019 05; 15(5):e1007756. PMID: 31095648.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    34. Liu L, Wei Q, Lin Q, Fang J, Wang H, Kwok H, Tang H, Nishiura K, Peng J, Tan Z, Wu T, Cheung KW, Chan KH, Alvarez X, Qin C, Lackner A, Perlman S, Yuen KY, Chen Z. Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection. JCI Insight. 2019 02 21; 4(4). PMID: 30830861.
      Citations: 244     Fields:    Translation:HumansAnimalsCells
    35. Yuan S, Chu H, Chan JF, Ye ZW, Wen L, Yan B, Lai PM, Tee KM, Huang J, Chen D, Li C, Zhao X, Yang D, Chiu MC, Yip C, Poon VK, Chan CC, Sze KH, Zhou J, Chan IH, Kok KH, To KK, Kao RY, Lau JY, Jin DY, Perlman S, Yuen KY. SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target. Nat Commun. 2019 01 10; 10(1):120. PMID: 30631056.
      Citations: 48     Fields:    Translation:Cells
    36. Jia W, Channappanavar R, Zhang C, Zhang C, Li M, Zhou H, Zhang S, Zhou P, Xu J, Shan S, Shi X, Wang X, Zhao J, Zhou D, Perlman S, Zhang L. Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection. Emerg Microbes Infect. 2019; 8(1):760-772. PMID: 31130102.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    37. Alshukairi AN, Zheng J, Zhao J, Nehdi A, Baharoon SA, Layqah L, Bokhari A, Al Johani SM, Samman N, Boudjelal M, Ten Eyck P, Ten Eyck P, Al-Mozaini MA, Zhao J, Perlman S, Alagaili AN. High Prevalence of MERS-CoV Infection in Camel Workers in Saudi Arabia. mBio. 2018 10 30; 9(5). PMID: 30377284.
      Citations: 34     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    38. Hua X, Vijay R, Channappanavar R, Athmer J, Meyerholz DK, Pagedar N, Tilley S, Perlman S. Nasal priming by a murine coronavirus provides protective immunity against lethal heterologous virus pneumonia. JCI Insight. 2018 06 07; 3(11). PMID: 29875310.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    39. Castaño-Rodriguez C, Honrubia JM, Gutiérrez-Álvarez J, DeDiego ML, Nieto-Torres JL, Jimenez-Guardeño JM, Regla-Nava JA, Fernandez-Delgado R, Verdia-Báguena C, Queralt-Martín M, Kochan G, Perlman S, Aguilella VM, Sola I, Enjuanes L. Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis. mBio. 2018 05 22; 9(3). PMID: 29789363.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    40. Athmer J, Fehr AR, Grunewald ME, Qu W, Wheeler DL, Graepel KW, Channappanavar R, Sekine A, Aldabeeb DS, Gale M, Denison MR, Perlman S. Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses. mBio. 2018 05 01; 9(3). PMID: 29717007.
      Citations: 7     Fields:    Translation:AnimalsCells
    41. Galasiti Kankanamalage AC, Kim Y, Damalanka VC, Rathnayake AD, Fehr AR, Mehzabeen N, Battaile KP, Lovell S, Lushington GH, Perlman S, Chang KO, Groutas WC. Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element. Eur J Med Chem. 2018 Apr 25; 150:334-346. PMID: 29544147.
      Citations: 28     Fields:    Translation:AnimalsCells
    42. Chu DKW, Hui KPY, Perera RAPM, Miguel E, Niemeyer D, Zhao J, Channappanavar R, Dudas G, Oladipo JO, Traoré A, Fassi-Fihri O, Ali A, Demissié GF, Muth D, Chan MCW, Nicholls JM, Meyerholz DK, Kuranga SA, Mamo G, Zhou Z, So RTY, Hemida MG, Webby RJ, Roger F, Rambaut A, Poon LLM, Perlman S, Drosten C, Chevalier V, Peiris M. MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity. Proc Natl Acad Sci U S A. 2018 03 20; 115(12):3144-3149. PMID: 29507189.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    43. Wheeler DL, Sariol A, Meyerholz DK, Perlman S. Microglia are required for protection against lethal coronavirus encephalitis in mice. J Clin Invest. 2018 03 01; 128(3):931-943. PMID: 29376888.
      Citations: 42     Fields:    Translation:AnimalsCells
    44. Canton J, Fehr AR, Fernandez-Delgado R, Gutierrez-Alvarez FJ, Sanchez-Aparicio MT, Sanchez-Aparicio MT, García-Sastre A, Perlman S, Enjuanes L, Sola I. MERS-CoV 4b protein interferes with the NF-?B-dependent innate immune response during infection. PLoS Pathog. 2018 01; 14(1):e1006838. PMID: 29370303.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    45. Grunewald ME, Fehr AR, Athmer J, Perlman S. The coronavirus nucleocapsid protein is ADP-ribosylated. Virology. 2018 04; 517:62-68. PMID: 29199039.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    46. Zheng J, Zheng J, Perlman S. Immune responses in influenza A virus and human coronavirus infections: an ongoing battle between the virus and host. Curr Opin Virol. 2018 02; 28:43-52. PMID: 29172107.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    47. Wheeler DL, Athmer J, Meyerholz DK, Perlman S. Murine Olfactory Bulb Interneurons Survive Infection with a Neurotropic Coronavirus. J Virol. 2017 Nov 15; 91(22). PMID: 28835503.
      Citations: 12     Fields:    
    48. Zhao J, Alshukairi AN, Baharoon SA, Ahmed WA, Bokhari AA, Nehdi AM, Layqah LA, Alghamdi MG, Alghamdi MG, Al Gethamy MM, Dada AM, Khalid I, Boujelal M, Al Johani SM, Vogel L, Subbarao K, Mangalam A, Wu C, Ten Eyck P, Ten Eyck P, Perlman S, Zhao J. Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses. Sci Immunol. 2017 Aug 04; 2(14). PMID: 28778905.
      Citations: 78     Fields:    
    49. Earnest JT, Hantak MP, Li K, McCray PB, Perlman S, Gallagher T. The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases. PLoS Pathog. 2017 Jul; 13(7):e1006546. PMID: 28759649.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    50. Vijay R, Fehr AR, Janowski AM, Athmer J, Wheeler DL, Grunewald M, Sompallae R, Kurup SP, Meyerholz DK, Sutterwala FS, Narumiya S, Perlman S. Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling. Proc Natl Acad Sci U S A. 2017 07 03; 114(27):E5444-E5453. PMID: 28630327.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    51. Channappanavar R, Perlman S. Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology. Semin Immunopathol. 2017 07; 39(5):529-539. PMID: 28466096.
      Citations: 660     Fields:    Translation:HumansAnimalsCells
    52. Channappanavar R, Fett C, Mack M, Ten Eyck PP, Ten Eyck PP, Meyerholz DK, Perlman S. Sex-Based Differences in Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection. J Immunol. 2017 05 15; 198(10):4046-4053. PMID: 28373583.
      Citations: 195     Fields:    Translation:AnimalsCells
    53. Li K, Wohlford-Lenane CL, Channappanavar R, Park JE, Earnest JT, Bair TB, Bates AM, Brogden KA, Flaherty HA, Gallagher T, Meyerholz DK, Perlman S, McCray PB. Mouse-adapted MERS coronavirus causes lethal lung disease in human DPP4 knockin mice. Proc Natl Acad Sci U S A. 2017 04 11; 114(15):E3119-E3128. PMID: 28348219.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    54. Chi H, Zheng X, Wang X, Wang C, Wang H, Gai W, Perlman S, Yang S, Zhao J, Xia X. DNA vaccine encoding Middle East respiratory syndrome coronavirus S1 protein induces protective immune responses in mice. Vaccine. 2017 04 11; 35(16):2069-2075. PMID: 28314561.
      Citations: 21     Fields:    Translation:AnimalsCells
    55. Athmer J, Fehr AR, Grunewald M, Smith EC, Denison MR, Perlman S. In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins. mBio. 2017 01 31; 8(1). PMID: 28143984.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    56. Perlman S, Zhao J. Roles of regulatory T cells and IL-10 in virus-induced demyelination. J Neuroimmunol. 2017 07 15; 308:6-11. PMID: 28065579.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    57. Tai W, Wang Y, Fett CA, Zhao G, Li F, Perlman S, Jiang S, Zhou Y, Du L. Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape Mutants. J Virol. 2017 Jan 01; 91(1). PMID: 27795425.
      Citations: 31     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    58. Fehr AR, Channappanavar R, Jankevicius G, Fett C, Zhao J, Athmer J, Meyerholz DK, Ahel I, Perlman S. The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection. mBio. 2016 12 13; 7(6). PMID: 27965448.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    59. Zhao Y, Wang C, Wang C, Qiu B, Li C, Wang H, Jin H, Gai W, Zheng X, Wang T, Sun W, Yan F, Gao Y, Wang Q, Wang Q, Yan J, Chen L, Chen L, Perlman S, Zhong N, Zhao J, Yang S, Xia X. Passive immunotherapy for Middle East Respiratory Syndrome coronavirus infection with equine immunoglobulin or immunoglobulin fragments in a mouse model. Antiviral Res. 2017 01; 137:125-130. PMID: 27890674.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    60. Du L, Tai W, Yang Y, Zhao G, Zhu Q, Sun S, Liu C, Tao X, Tseng CK, Perlman S, Jiang S, Zhou Y, Li F. Introduction of neutralizing immunogenicity index to the rational design of MERS coronavirus subunit vaccines. Nat Commun. 2016 11 22; 7:13473. PMID: 27874853.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    61. de Wilde AH, Falzarano D, Zevenhoven-Dobbe JC, Beugeling C, Fett C, Martellaro C, Posthuma CC, Feldmann H, Perlman S, Snijder EJ. Alisporivir inhibits MERS- and SARS-coronavirus replication in cell culture, but not SARS-coronavirus infection in a mouse model. Virus Res. 2017 01 15; 228:7-13. PMID: 27840112.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    62. Park JE, Li K, Barlan A, Fehr AR, Perlman S, McCray PB, Gallagher T. Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism. Proc Natl Acad Sci U S A. 2016 10 25; 113(43):12262-12267. PMID: 27791014.
      Citations: 97     Fields:    Translation:HumansCells
    63. Fehr AR, Channappanavar R, Perlman S. Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus. Annu Rev Med. 2017 01 14; 68:387-399. PMID: 27576010.
      Citations: 80     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    64. Zhao J, Zhao J, Mangalam AK, Channappanavar R, Fett C, Meyerholz DK, Agnihothram S, Baric RS, David CS, Perlman S. Airway Memory CD4(+) T Cells Mediate Protective Immunity against Emerging Respiratory Coronaviruses. Immunity. 2016 06 21; 44(6):1379-91. PMID: 27287409.
      Citations: 120     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    65. Alshukairi AN, Khalid I, Ahmed WA, Dada AM, Bayumi DT, Malic LS, Althawadi S, Ignacio K, Alsalmi HS, Al-Abdely HM, Wali GY, Qushmaq IA, Alraddadi BM, Alraddadi BM, Perlman S. Antibody Response and Disease Severity in Healthcare Worker MERS Survivors. Emerg Infect Dis. 2016 06; 22(6). PMID: 27192543.
      Citations: 50     Fields:    Translation:HumansCells
    66. Perlman S, Vijay R. Middle East respiratory syndrome vaccines. Int J Infect Dis. 2016 Jun; 47:23-8. PMID: 27062985.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    67. Luke T, Wu H, Zhao J, Channappanavar R, Coleman CM, Jiao JA, Matsushita H, Liu Y, Postnikova EN, Ork BL, Glenn G, Flyer D, Defang G, Raviprakash K, Kochel T, Wang J, Nie W, Smith G, Hensley LE, Olinger GG, Kuhn JH, Holbrook MR, Johnson RF, Perlman S, Sullivan E, Frieman MB. Human polyclonal immunoglobulin G from transchromosomic bovines inhibits MERS-CoV in vivo. Sci Transl Med. 2016 Feb 17; 8(326):326ra21. PMID: 26888429.
      Citations: 50     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    68. Vijay R, Perlman S. Middle East respiratory syndrome and severe acute respiratory syndrome. Curr Opin Virol. 2016 Feb; 16:70-76. PMID: 26855039.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    69. Channappanavar R, Fehr AR, Vijay R, Mack M, Zhao J, Meyerholz DK, Perlman S. Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice. . 2016 Feb 10; 19(2):181-93. PMID: 26867177.
      Citations:    
    70. Bedell K, Buchaklian AH, Perlman S. Efficacy of an Automated Multiple Emitter Whole-Room Ultraviolet-C Disinfection System Against Coronaviruses MHV and MERS-CoV. Infect Control Hosp Epidemiol. 2016 May; 37(5):598-9. PMID: 26818469.
      Citations: 28     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    71. Jimenez-Guardeño JM, Regla-Nava JA, Nieto-Torres JL, DeDiego ML, Castaño-Rodriguez C, Fernandez-Delgado R, Perlman S, Enjuanes L. Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine. PLoS Pathog. 2015 Oct; 11(10):e1005215. PMID: 26513244.
      Citations: 45     Fields:    Translation:AnimalsCells
    72. Li K, Wohlford-Lenane C, Perlman S, Zhao J, Jewell AK, Reznikov LR, Gibson-Corley KN, Meyerholz DK, McCray PB. Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4. J Infect Dis. 2016 Mar 01; 213(5):712-22. PMID: 26486634.
      Citations: 149     Fields:    Translation:HumansAnimalsCells
    73. Li Y, Wan Y, Liu P, Zhao J, Lu G, Qi J, Wang Q, Lu X, Wu Y, Liu W, Zhang B, Yuen KY, Perlman S, Gao GF, Yan J. A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein. Cell Res. 2015 Nov; 25(11):1237-49. PMID: 26391698.
      Citations: 59     Fields:    Translation:AnimalsCells
    74. Vijay R, Hua X, Meyerholz DK, Miki Y, Yamamoto K, Gelb M, Murakami M, Perlman S. Critical role of phospholipase A2 group IID in age-related susceptibility to severe acute respiratory syndrome-CoV infection. J Exp Med. 2015 Oct 19; 212(11):1851-68. PMID: 26392224.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    75. Corti D, Zhao J, Pedotti M, Simonelli L, Agnihothram S, Fett C, Fernandez-Rodriguez B, Foglierini M, Agatic G, Vanzetta F, Gopal R, Langrish CJ, Barrett NA, Sallusto F, Baric RS, Varani L, Zambon M, Perlman S, Lanzavecchia A. Prophylactic and postexposure efficacy of a potent human monoclonal antibody against MERS coronavirus. Proc Natl Acad Sci U S A. 2015 Aug 18; 112(33):10473-8. PMID: 26216974.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    76. Perlman S. Research Driven by Curiosity: The Journey from Basic Molecular Biology and Virology to Studies of Human Pathogenic Coronaviruses. PLoS Pathog. 2015 Jul; 11(7):e1005023. PMID: 26172373.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    77. Channappanavar R, Lu L, Xia S, Du L, Meyerholz DK, Perlman S, Jiang S. Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV Infection. J Infect Dis. 2015 Dec 15; 212(12):1894-903. PMID: 26164863.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    78. Hui DS, Perlman S, Zumla A. Spread of MERS to South Korea and China. Lancet Respir Med. 2015 Jul; 3(7):509-10. PMID: 26050550.
      Citations: 41     Fields:    Translation:HumansPHPublic Health
    79. Zumla A, Hui DS, Perlman S. Middle East respiratory syndrome. Lancet. 2015 Sep 05; 386(9997):995-1007. PMID: 26049252.
      Citations: 332     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    80. Zhao J, Perera RA, Kayali G, Meyerholz D, Perlman S, Peiris M. Passive immunotherapy with dromedary immune serum in an experimental animal model for Middle East respiratory syndrome coronavirus infection. J Virol. 2015 Jun; 89(11):6117-20. PMID: 25787284.
      Citations: 31     Fields:    Translation:AnimalsCells
    81. Mielech AM, Deng X, Chen Y, Kindler E, Wheeler DL, Mesecar AD, Thiel V, Perlman S, Baker SC. Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis. J Virol. 2015 May; 89(9):4907-17. PMID: 25694594.
      Citations: 25     Fields:    Translation:AnimalsCells
    82. Zhang N, Channappanavar R, Ma C, Wang L, Tang J, Garron T, Tao X, Tasneem S, Lu L, Tseng CT, Zhou Y, Perlman S, Jiang S, Du L. Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus. Cell Mol Immunol. 2016 Mar; 13(2):180-90. PMID: 25640653.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    83. Regla-Nava JA, Nieto-Torres JL, Jimenez-Guardeño JM, Fernandez-Delgado R, Fett C, Castaño-Rodríguez C, Perlman S, Enjuanes L, DeDiego ML. Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates. J Virol. 2015 Apr; 89(7):3870-87. PMID: 25609816.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    84. Zumla A, Perlman S, McNabb SJN, Shaikh A, Shaikh A, Heymann DL, McCloskey B, Hui DS. Middle East respiratory syndrome in the shadow of Ebola. Lancet Respir Med. 2015 Feb; 3(2):100-102. PMID: 25592990.
      Citations: 7     Fields:    Translation:HumansCells
    85. Fehr AR, Perlman S. Coronaviruses: an overview of their replication and pathogenesis. Methods Mol Biol. 2015; 1282:1-23. PMID: 25720466.
      Citations: 720     Fields:    Translation:HumansAnimalsCells
    86. Fehr AR, Athmer J, Channappanavar R, Phillips JM, Meyerholz DK, Perlman S. The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis. J Virol. 2015 Feb; 89(3):1523-36. PMID: 25428866.
      Citations: 55     Fields:    Translation:AnimalsCells
    87. Trujillo JA, Croft NP, Dudek NL, Channappanavar R, Theodossis A, Webb AI, Dunstone MA, Illing PT, Butler NS, Fett C, Tscharke DC, Rossjohn J, Perlman S, Purcell AW. The cellular redox environment alters antigen presentation. J Biol Chem. 2014 Oct 03; 289(40):27979-91. PMID: 25135637.
      Citations: 14     Fields:    Translation:AnimalsCells
    88. Zhao J, Zhao J, Perlman S. Virus-specific regulatory T cells ameliorate encephalitis by repressing effector T cell functions from priming to effector stages. PLoS Pathog. 2014 Aug; 10(8):e1004279. PMID: 25102154.
      Citations: 18     Fields:    Translation:AnimalsCells
    89. Channappanavar R, Zhao J, Perlman S. T cell-mediated immune response to respiratory coronaviruses. Immunol Res. 2014 Aug; 59(1-3):118-28. PMID: 24845462.
      Citations: 167     Fields:    Translation:HumansAnimalsCells
    90. Channappanavar R, Fett C, Zhao J, Meyerholz DK, Perlman S. Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection. J Virol. 2014 Oct; 88(19):11034-44. PMID: 25056892.
      Citations: 124     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    91. Trujillo JA, Gras S, Twist KA, Croft NP, Channappanavar R, Rossjohn J, Purcell AW, Perlman S. Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes. J Immunol. 2014 Jun 01; 192(11):5245-56. PMID: 24795457.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    92. Lin SY, Liu CL, Chang YM, Zhao J, Perlman S, Hou MH. Structural basis for the identification of the N-terminal domain of coronavirus nucleocapsid protein as an antiviral target. J Med Chem. 2014 Mar 27; 57(6):2247-57. PMID: 24564608.
      Citations: 35     Fields:    Translation:HumansCells
    93. Zhao J, Li K, Wohlford-Lenane C, Agnihothram SS, Fett C, Zhao J, Gale MJ, Baric RS, Enjuanes L, Gallagher T, McCray PB, Perlman S. Rapid generation of a mouse model for Middle East respiratory syndrome. Proc Natl Acad Sci U S A. 2014 Apr 01; 111(13):4970-5. PMID: 24599590.
      Citations: 208     Fields:    Translation:HumansAnimalsCells
    94. Barlan A, Zhao J, Sarkar MK, Li K, McCray PB, Perlman S, Gallagher T. Receptor variation and susceptibility to Middle East respiratory syndrome coronavirus infection. J Virol. 2014 May; 88(9):4953-61. PMID: 24554656.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    95. DeDiego ML, Nieto-Torres JL, Regla-Nava JA, Jimenez-Guardeño JM, Fernandez-Delgado R, Fett C, Castaño-Rodriguez C, Perlman S, Enjuanes L. Inhibition of NF-?B-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival. J Virol. 2014 Jan; 88(2):913-24. PMID: 24198408.
      Citations: 125     Fields:    Translation:HumansAnimalsCells
    96. Perlman S. The Middle East respiratory syndrome--how worried should we be? mBio. 2013 Aug 20; 4(4). PMID: 23963179.
      Citations: 7     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    97. Zhao J, Fett C, Pewe L, Zhao J, Perlman S. Development of transgenic mice expressing a coronavirus-specific public CD4 T cell receptor. J Immunol Methods. 2013 Oct 31; 396(1-2):56-64. PMID: 23928495.
      Citations: 1     Fields:    Translation:AnimalsCells
    98. Perlman S, McCray PB. Person-to-person spread of the MERS coronavirus--an evolving picture. N Engl J Med. 2013 Aug 01; 369(5):466-7. PMID: 23902487.
      Citations: 17     Fields:    Translation:HumansCellsPHPublic Health
    99. de Groot RJ, Baker SC, Baric RS, Brown CS, Drosten C, Enjuanes L, Fouchier RA, Galiano M, Gorbalenya AE, Memish ZA, Perlman S, Poon LL, Snijder EJ, Stephens GM, Woo PC, Zaki AM, Zambon M, Ziebuhr J. Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group. J Virol. 2013 Jul; 87(14):7790-2. PMID: 23678167.
      Citations: 407     Fields:    Translation:HumansCells
    100. Fett C, DeDiego ML, Regla-Nava JA, Enjuanes L, Perlman S. Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein. J Virol. 2013 Jun; 87(12):6551-9. PMID: 23576515.
      Citations: 51     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    101. Chen IJ, Yuann JM, Chang YM, Lin SY, Zhao J, Perlman S, Shen YY, Huang TH, Hou MH. Crystal structure-based exploration of the important role of Arg106 in the RNA-binding domain of human coronavirus OC43 nucleocapsid protein. Biochim Biophys Acta. 2013 Jun; 1834(6):1054-62. PMID: 23501675.
      Citations: 17     Fields:    Translation:HumansCells
    102. Gallagher T, Perlman S. Public health: Broad reception for coronavirus. Nature. 2013 Mar 14; 495(7440):176-7. PMID: 23486053.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    103. Perlman S, Zhao J. Human coronavirus EMC is not the same as severe acute respiratory syndrome coronavirus. mBio. 2013 Jan 15; 4(1). PMID: 23322635.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    104. Trujillo JA, Fleming EL, Perlman S. Transgenic CCL2 expression in the central nervous system results in a dysregulated immune response and enhanced lethality after coronavirus infection. J Virol. 2013 Mar; 87(5):2376-89. PMID: 23269787.
      Citations: 19     Fields:    Translation:AnimalsCells
    105. Zhao J, Wohlford-Lenane C, Zhao J, Fleming E, Lane TE, McCray PB, Perlman S. Intranasal treatment with poly(I•C) protects aged mice from lethal respiratory virus infections. J Virol. 2012 Nov; 86(21):11416-24. PMID: 22915814.
      Citations: 48     Fields:    Translation:AnimalsCells
    106. Zhao J, Zhao J, Legge K, Perlman S. Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice. J Clin Invest. 2011 Dec; 121(12):4921-30. PMID: 22105170.
      Citations: 100     Fields:    Translation:AnimalsCells
    107. DeDiego ML, Nieto-Torres JL, Jiménez-Guardeño JM, Regla-Nava JA, Alvarez E, Oliveros JC, Zhao J, Fett C, Perlman S, Enjuanes L. Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis. PLoS Pathog. 2011 Oct; 7(10):e1002315. PMID: 22028656.
      Citations: 76     Fields:    Translation:HumansCells
    108. Zhao J, Zhao J, Fett C, Trandem K, Fleming E, Perlman S. IFN-?- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis. J Exp Med. 2011 Aug 01; 208(8):1571-7. PMID: 21746812.
      Citations: 44     Fields:    Translation:AnimalsCells
    109. Trandem K, Jin Q, Weiss KA, James BR, Zhao J, Perlman S. Virally expressed interleukin-10 ameliorates acute encephalomyelitis and chronic demyelination in coronavirus-infected mice. J Virol. 2011 Jul; 85(14):6822-31. PMID: 21593179.
      Citations: 15     Fields:    Translation:AnimalsCells
    110. Trandem K, Zhao J, Fleming E, Perlman S. Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitis. J Immunol. 2011 Mar 15; 186(6):3642-52. PMID: 21317392.
      Citations: 71     Fields:    Translation:AnimalsCells
    111. Shulla A, Heald-Sargent T, Subramanya G, Zhao J, Perlman S, Gallagher T. A transmembrane serine protease is linked to the severe acute respiratory syndrome coronavirus receptor and activates virus entry. J Virol. 2011 Jan; 85(2):873-82. PMID: 21068237.
      Citations: 213     Fields:    Translation:HumansCells
    112. Zhou H, Zhao J, Perlman S. Autocrine interferon priming in macrophages but not dendritic cells results in enhanced cytokine and chemokine production after coronavirus infection. mBio. 2010 Oct 19; 1(4). PMID: 20978536.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    113. Zhao J, Zhao J, Perlman S. T cell responses are required for protection from clinical disease and for virus clearance in severe acute respiratory syndrome coronavirus-infected mice. J Virol. 2010 Sep; 84(18):9318-25. PMID: 20610717.
      Citations: 116     Fields:    Translation:AnimalsCells
    114. Trandem K, Anghelina D, Zhao J, Perlman S. Regulatory T cells inhibit T cell proliferation and decrease demyelination in mice chronically infected with a coronavirus. J Immunol. 2010 Apr 15; 184(8):4391-400. PMID: 20208000.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    115. Netland J, DeDiego ML, Zhao J, Fett C, Álvarez E, Nieto-Torres JL, Enjuanes L, Perlman S. Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease. Virology. 2010 Mar 30; 399(1):120-128. PMID: 20110095.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    116. Zhou H, Ferraro D, Zhao J, Hussain S, Shao J, Trujillo J, Netland J, Gallagher T, Perlman S. The N-terminal region of severe acute respiratory syndrome coronavirus protein 6 induces membrane rearrangement and enhances virus replication. J Virol. 2010 Apr; 84(7):3542-51. PMID: 20106914.
      Citations: 18     Fields:    Translation:HumansCells
    117. Zhao J, Zhao J, Van Rooijen N, Perlman S. Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice. PLoS Pathog. 2009 Oct; 5(10):e1000636. PMID: 19851468.
      Citations: 73     Fields:    Translation:AnimalsCells
    118. Zhao J, Zhao J, Perlman S. De novo recruitment of antigen-experienced and naive T cells contributes to the long-term maintenance of antiviral T cell populations in the persistently infected central nervous system. J Immunol. 2009 Oct 15; 183(8):5163-70. PMID: 19786545.
      Citations: 19     Fields:    Translation:AnimalsCells
    119. Wohlford-Lenane CL, Meyerholz DK, Perlman S, Zhou H, Tran D, Selsted ME, McCray PB. Rhesus theta-defensin prevents death in a mouse model of severe acute respiratory syndrome coronavirus pulmonary disease. J Virol. 2009 Nov; 83(21):11385-90. PMID: 19710146.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    120. Perlman S, Netland J. Coronaviruses post-SARS: update on replication and pathogenesis. Nat Rev Microbiol. 2009 Jun; 7(6):439-50. PMID: 19430490.
      Citations: 495     Fields:    Translation:HumansAnimalsCells
    121. Anghelina D, Zhao J, Trandem K, Perlman S. Role of regulatory T cells in coronavirus-induced acute encephalitis. Virology. 2009 Mar 15; 385(2):358-67. PMID: 19141357.
      Citations: 28     Fields:    Translation:AnimalsCells
    122. Zhao J, Falcón A, Zhou H, Netland J, Enjuanes L, Pérez Breña P, Perlman S. Severe acute respiratory syndrome coronavirus protein 6 is required for optimal replication. J Virol. 2009 Mar; 83(5):2368-73. PMID: 19091867.
      Citations: 22     Fields:    Translation:AnimalsCells
    123. Whitman L, Zhou H, Perlman S, Lane TE. IFN-gamma-mediated suppression of coronavirus replication in glial-committed progenitor cells. Virology. 2009 Feb 05; 384(1):209-15. PMID: 19059617.
      Citations: 9     Fields:    Translation:AnimalsCells
    124. Butler NS, Theodossis A, Webb AI, Nastovska R, Ramarathinam SH, Dunstone MA, Rossjohn J, Purcell AW, Perlman S. Prevention of cytotoxic T cell escape using a heteroclitic subdominant viral T cell determinant. PLoS Pathog. 2008 Oct; 4(10):e1000186. PMID: 18949029.
      Citations: 7     Fields:    Translation:AnimalsCells
    125. Netland J, Meyerholz DK, Moore S, Moore S, Cassell M, Perlman S. Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2. J Virol. 2008 Aug; 82(15):7264-75. PMID: 18495771.
      Citations: 374     Fields:    Translation:HumansAnimalsCells
    126. Dediego ML, Pewe L, Alvarez E, Rejas MT, Perlman S, Enjuanes L. Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice. Virology. 2008 Jul 05; 376(2):379-89. PMID: 18452964.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    127. Hussain S, Perlman S, Gallagher TM. Severe acute respiratory syndrome coronavirus protein 6 accelerates murine hepatitis virus infections by more than one mechanism. J Virol. 2008 Jul; 82(14):7212-22. PMID: 18448520.
      Citations: 21     Fields:    Translation:HumansCells
    128. Butler NS, Theodossis A, Webb AI, Dunstone MA, Nastovska R, Ramarathinam SH, Rossjohn J, Purcell AW, Perlman S. Structural and biological basis of CTL escape in coronavirus-infected mice. J Immunol. 2008 Mar 15; 180(6):3926-37. PMID: 18322201.
      Citations: 10     Fields:    Translation:AnimalsCells
    129. Templeton SP, Perlman S. Role of IFN-gamma responsiveness in CD8 T-cell-mediated viral clearance and demyelination in coronavirus-infected mice. J Neuroimmunol. 2008 Feb; 194(1-2):18-26. PMID: 18082272.
      Citations: 5     Fields:    Translation:AnimalsCells
    130. Templeton SP, Kim TS, O'Malley K, Perlman S. Maturation and localization of macrophages and microglia during infection with a neurotropic murine coronavirus. Brain Pathol. 2008 Jan; 18(1):40-51. PMID: 17935605.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    131. Butler NS, Dandekar AA, Perlman S. Antiviral antibodies are necessary to prevent cytotoxic T-lymphocyte escape in mice infected with a coronavirus. J Virol. 2007 Dec; 81(24):13291-8. PMID: 17913802.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    132. Netland J, Ferraro D, Pewe L, Olivares H, Gallagher T, Perlman S. Enhancement of murine coronavirus replication by severe acute respiratory syndrome coronavirus protein 6 requires the N-terminal hydrophobic region but not C-terminal sorting motifs. J Virol. 2007 Oct; 81(20):11520-5. PMID: 17670827.
      Citations: 16     Fields:    Translation:AnimalsCells
    133. Templeton SP, Perlman S. Pathogenesis of acute and chronic central nervous system infection with variants of mouse hepatitis virus, strain JHM. Immunol Res. 2007; 39(1-3):160-72. PMID: 17917063.
      Citations: 20     Fields:    Translation:AnimalsCells
    134. Tangudu C, Olivares H, Netland J, Perlman S, Gallagher T. Severe acute respiratory syndrome coronavirus protein 6 accelerates murine coronavirus infections. J Virol. 2007 Feb; 81(3):1220-9. PMID: 17108045.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    135. Kedzierska K, Day EB, Pi J, Heard SB, Doherty PC, Turner SJ, Perlman S. Quantification of repertoire diversity of influenza-specific epitopes with predominant public or private TCR usage. J Immunol. 2006 Nov 15; 177(10):6705-12. PMID: 17082583.
      Citations: 32     Fields:    Translation:AnimalsCells
    136. Zhou H, Perlman S. Mouse hepatitis virus does not induce Beta interferon synthesis and does not inhibit its induction by double-stranded RNA. J Virol. 2007 Jan; 81(2):568-74. PMID: 17079305.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    137. McCray PB, Pewe L, Wohlford-Lenane C, Hickey M, Manzel L, Shi L, Netland J, Jia HP, Halabi C, Sigmund CD, Meyerholz DK, Kirby P, Look DC, Perlman S. Lethal infection of K18-hACE2 mice infected with severe acute respiratory syndrome coronavirus. J Virol. 2007 Jan; 81(2):813-21. PMID: 17079315.
      Citations: 225     Fields:    Translation:HumansAnimalsCells
    138. Anghelina D, Pewe L, Perlman S. Pathogenic role for virus-specific CD4 T cells in mice with coronavirus-induced acute encephalitis. Am J Pathol. 2006 Jul; 169(1):209-22. PMID: 16816374.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    139. Zhou H, Perlman S. Preferential infection of mature dendritic cells by mouse hepatitis virus strain JHM. J Virol. 2006 Mar; 80(5):2506-14. PMID: 16474157.
      Citations: 21     Fields:    Translation:AnimalsCells
    140. Butler N, Pewe L, Trandem K, Perlman S. Murine encephalitis caused by HCoV-OC43, a human coronavirus with broad species specificity, is partly immune-mediated. Virology. 2006 Apr 10; 347(2):410-21. PMID: 16413043.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    141. Zhou H, Perlman S. Preferential infection of mature dendritic cells by the JHM strain of mouse hepatitis virus. Adv Exp Med Biol. 2006; 581:411-4. PMID: 17037570.
      Citations: 2     Fields:    Translation:AnimalsCells
    142. Jia HP, Look DC, Hickey M, Shi L, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. Infection of human airway epithelia by SARS coronavirus is associated with ACE2 expression and localization. Adv Exp Med Biol. 2006; 581:479-84. PMID: 17037581.
      Citations: 13     Fields:    Translation:HumansCells
    143. Pewe L, Zhou H, Netland J, Tangadu C, Olivares H, Shi L, Look D, Gallagher T, Perlman S. A SARS-CoV-specific protein enhances virulence of an attenuated strain of mouse hepatitis virus. Adv Exp Med Biol. 2006; 581:493-8. PMID: 17037583.
      Citations: 3     Fields:    Translation:Cells
    144. Butler N, Pewe L, Trandem K, Perlman S. HCoV-OC43-induced encephalitis is in part immune-mediated. Adv Exp Med Biol. 2006; 581:531-4. PMID: 17037592.
      Citations:    Fields:    Translation:HumansAnimalsCells
    145. Jia HP, Look DC, Shi L, Hickey M, Pewe L, Netland J, Farzan M, Wohlford-Lenane C, Perlman S, McCray PB. ACE2 receptor expression and severe acute respiratory syndrome coronavirus infection depend on differentiation of human airway epithelia. J Virol. 2005 Dec; 79(23):14614-21. PMID: 16282461.
      Citations: 250     Fields:    Translation:HumansCells
    146. Perlman S, Dandekar AA. Immunopathogenesis of coronavirus infections: implications for SARS. Nat Rev Immunol. 2005 Dec; 5(12):917-27. PMID: 16322745.
      Citations: 178     Fields:    Translation:HumansAnimalsCells
    147. Pewe L, Zhou H, Netland J, Tangudu C, Olivares H, Shi L, Look D, Gallagher T, Perlman S. A severe acute respiratory syndrome-associated coronavirus-specific protein enhances virulence of an attenuated murine coronavirus. J Virol. 2005 Sep; 79(17):11335-42. PMID: 16103185.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    148. Dandekar AA, O'Malley K, Perlman S. Important roles for gamma interferon and NKG2D in gammadelta T-cell-induced demyelination in T-cell receptor beta-deficient mice infected with a coronavirus. J Virol. 2005 Aug; 79(15):9388-96. PMID: 16014902.
      Citations: 11     Fields:    Translation:AnimalsCells
    149. Kim TS, Perlman S. Viral expression of CCL2 is sufficient to induce demyelination in RAG1-/- mice infected with a neurotropic coronavirus. J Virol. 2005 Jun; 79(11):7113-20. PMID: 15890951.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    150. Kim TS, Perlman S. Virus-specific antibody, in the absence of T cells, mediates demyelination in mice infected with a neurotropic coronavirus. Am J Pathol. 2005 Mar; 166(3):801-9. PMID: 15743792.
      Citations: 12     Fields:    Translation:AnimalsCells
    151. Pewe LL, Netland JM, Heard SB, Perlman S. Very diverse CD8 T cell clonotypic responses after virus infections. J Immunol. 2004 Mar 01; 172(5):3151-6. PMID: 14978121.
      Citations: 25     Fields:    Translation:AnimalsCells
    152. Dandekar AA, Anghelina D, Perlman S. Bystander CD8 T-cell-mediated demyelination is interferon-gamma-dependent in a coronavirus model of multiple sclerosis. Am J Pathol. 2004 Feb; 164(2):363-9. PMID: 14742242.
      Citations: 14     Fields:    Translation:AnimalsCells
    153. Dandekar AA, Jacobsen G, Waldschmidt TJ, Perlman S. Antibody-mediated protection against cytotoxic T-cell escape in coronavirus-induced demyelination. J Virol. 2003 Nov; 77(22):11867-74. PMID: 14581523.
      Citations: 9     Fields:    Translation:AnimalsCells
    154. Ontiveros E, Kim TS, Gallagher TM, Perlman S. Enhanced virulence mediated by the murine coronavirus, mouse hepatitis virus strain JHM, is associated with a glycine at residue 310 of the spike glycoprotein. J Virol. 2003 Oct; 77(19):10260-9. PMID: 12970410.
      Citations: 40     Fields:    Translation:AnimalsCells
    155. Kim TS, Perlman S. Protection against CTL escape and clinical disease in a murine model of virus persistence. J Immunol. 2003 Aug 15; 171(4):2006-13. PMID: 12902505.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    156. Haring JS, Perlman S. Bystander CD4 T cells do not mediate demyelination in mice infected with a neurotropic coronavirus. J Neuroimmunol. 2003 Apr; 137(1-2):42-50. PMID: 12667646.
      Citations: 8     Fields:    Translation:AnimalsCells
    157. Dandekar AA, Perlman S. Virus-induced demyelination in nude mice is mediated by gamma delta T cells. Am J Pathol. 2002 Oct; 161(4):1255-63. PMID: 12368199.
      Citations: 19     Fields:    Translation:AnimalsCells
    158. Haring JS, Pewe LL, Perlman S. Bystander CD8 T cell-mediated demyelination after viral infection of the central nervous system. J Immunol. 2002 Aug 01; 169(3):1550-5. PMID: 12133983.
      Citations: 27     Fields:    Translation:AnimalsCells
    159. Pewe L, Haring J, Perlman S. CD4 T-cell-mediated demyelination is increased in the absence of gamma interferon in mice infected with mouse hepatitis virus. J Virol. 2002 Jul; 76(14):7329-33. PMID: 12072531.
      Citations: 23     Fields:    Translation:AnimalsCells
    160. Pewe L, Perlman S. Cutting edge: CD8 T cell-mediated demyelination is IFN-gamma dependent in mice infected with a neurotropic coronavirus. J Immunol. 2002 Feb 15; 168(4):1547-51. PMID: 11823480.
      Citations: 33     Fields:    Translation:AnimalsCells
    161. Ontiveros E, Kuo L, Masters PS, Perlman S. Inactivation of expression of gene 4 of mouse hepatitis virus strain JHM does not affect virulence in the murine CNS. Virology. 2001 Oct 25; 289(2):230-8. PMID: 11689046.
      Citations: 52     Fields:    Translation:AnimalsCells
    162. Haring J, Perlman S. Mouse hepatitis virus. Curr Opin Microbiol. 2001 Aug; 4(4):462-6. PMID: 11495812.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    163. Dandekar AA, Wu GF, Pewe L, Perlman S. Axonal damage is T cell mediated and occurs concomitantly with demyelination in mice infected with a neurotropic coronavirus. J Virol. 2001 Jul; 75(13):6115-20. PMID: 11390613.
      Citations: 31     Fields:    Translation:AnimalsCells
    164. Kolb AF, Pewe L, Webster J, Perlman S, Whitelaw CB, Siddell SG. Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis. J Virol. 2001 Mar; 75(6):2803-9. PMID: 11222704.
      Citations: 13     Fields:    Translation:AnimalsCells
    165. Haring JS, Pewe LL, Perlman S. High-magnitude, virus-specific CD4 T-cell response in the central nervous system of coronavirus-infected mice. J Virol. 2001 Mar; 75(6):3043-7. PMID: 11222733.
      Citations: 19     Fields:    Translation:AnimalsCells
    166. Wu GF, Dandekar AA, Pewe L, Perlman S. The role of CD4 and CD8 T cells in MHV-JHM-induced demyelination. Adv Exp Med Biol. 2001; 494:341-7. PMID: 11774490.
      Citations: 7     Fields:    Translation:AnimalsCells
    167. Ontiveros E, Kuo L, Masters P, Perlman S. Analysis of nonessential gene function in recombinant MHV-JHM. Gene 4 knockout recombinant virus. Adv Exp Med Biol. 2001; 494:83-9. PMID: 11774550.
      Citations: 4     Fields:    Translation:AnimalsCells
    168. Wang G, Deering C, Macke M, Shao J, Burns R, Blau DM, Holmes KV, Davidson BL, Perlman S, McCray PB. Human coronavirus 229E infects polarized airway epithelia from the apical surface. J Virol. 2000 Oct; 74(19):9234-9. PMID: 10982370.
      Citations: 32     Fields:    Translation:HumansCells
    169. Wu GF, Dandekar AA, Pewe L, Perlman S. CD4 and CD8 T cells have redundant but not identical roles in virus-induced demyelination. J Immunol. 2000 Aug 15; 165(4):2278-86. PMID: 10925317.
      Citations: 99     Fields:    Translation:AnimalsCells
    170. Wu GF, Pewe L, Perlman S. Coronavirus-induced demyelination occurs in the absence of inducible nitric oxide synthase. J Virol. 2000 Aug; 74(16):7683-6. PMID: 10906226.
      Citations: 11     Fields:    Translation:AnimalsCells
    171. Pewe L, Heard SB, Bergmann C, Dailey MO, Perlman S. Selection of CTL escape mutants in mice infected with a neurotropic coronavirus: quantitative estimate of TCR diversity in the infected central nervous system. J Immunol. 1999 Dec 01; 163(11):6106-13. PMID: 10570300.
      Citations: 20     Fields:    Translation:AnimalsCells
    172. Wu GF, Perlman S. Macrophage infiltration, but not apoptosis, is correlated with immune-mediated demyelination following murine infection with a neurotropic coronavirus. J Virol. 1999 Oct; 73(10):8771-80. PMID: 10482631.
      Citations: 59     Fields:    Translation:AnimalsCells
    173. Xue S, Sun N, Van Rooijen N, Perlman S. Depletion of blood-borne macrophages does not reduce demyelination in mice infected with a neurotropic coronavirus. J Virol. 1999 Aug; 73(8):6327-34. PMID: 10400724.
      Citations: 29     Fields:    Translation:AnimalsCells
    174. Pewe L, Perlman S. Immune response to the immunodominant epitope of mouse hepatitis virus is polyclonal, but functionally monospecific in C57Bl/6 mice. Virology. 1999 Mar 01; 255(1):106-16. PMID: 10049826.
      Citations: 8     Fields:    Translation:AnimalsCells
    175. Pewe L, Xue S, Perlman S. Infection with cytotoxic T-lymphocyte escape mutants results in increased mortality and growth retardation in mice infected with a neurotropic coronavirus. J Virol. 1998 Jul; 72(7):5912-8. PMID: 9621053.
      Citations: 8     Fields:    Translation:AnimalsCells
    176. Perlman S. Pathogenesis of coronavirus-induced infections. Review of pathological and immunological aspects. Adv Exp Med Biol. 1998; 440:503-13. PMID: 9782322.
      Citations: 27     Fields:    Translation:AnimalsCells
    177. Perlman S, Pewe L. Role of CTL mutants in demyelination induced by mouse hepatitis virus, strain JHM. Adv Exp Med Biol. 1998; 440:515-9. PMID: 9782323.
      Citations: 5     Fields:    Translation:AnimalsCells
    178. Xue S, Perlman S. Antigen specificity of CD4 T cell response in the central nervous system of mice infected with mouse hepatitis virus. Virology. 1997 Nov 10; 238(1):68-78. PMID: 9375010.
      Citations: 13     Fields:    Translation:AnimalsCells
    179. Pewe L, Xue S, Perlman S. Cytotoxic T-cell-resistant variants arise at early times after infection in C57BL/6 but not in SCID mice infected with a neurotropic coronavirus. J Virol. 1997 Oct; 71(10):7640-7. PMID: 9311846.
      Citations: 11     Fields:    Translation:AnimalsCells
    180. Grzybicki DM, Kwack KB, Perlman S, Murphy SP. Nitric oxide synthase type II expression by different cell types in MHV-JHM encephalitis suggests distinct roles for nitric oxide in acute versus persistent virus infection. J Neuroimmunol. 1997 Mar; 73(1-2):15-27. PMID: 9058755.
      Citations: 10     Fields:    Translation:AnimalsCells
    181. Pewe L, Wu GF, Barnett EM, Castro RF, Perlman S. Cytotoxic T cell-resistant variants are selected in a virus-induced demyelinating disease. Immunity. 1996 Sep; 5(3):253-62. PMID: 8808680.
      Citations: 38     Fields:    Translation:AnimalsCells
    182. Castro RF, Perlman S. Differential antigen recognition by T cells from the spleen and central nervous system of coronavirus-infected mice. Virology. 1996 Aug 01; 222(1):247-51. PMID: 8806504.
      Citations: 6     Fields:    Translation:AnimalsCells
    183. Castro RF, Perlman S. CD8+ T-cell epitopes within the surface glycoprotein of a neurotropic coronavirus and correlation with pathogenicity. J Virol. 1995 Dec; 69(12):8127-31. PMID: 7494335.
      Citations: 48     Fields:    Translation:AnimalsCells
    184. Sun N, Grzybicki D, Castro RF, Murphy S, Perlman S. Activation of astrocytes in the spinal cord of mice chronically infected with a neurotropic coronavirus. Virology. 1995 Nov 10; 213(2):482-93. PMID: 7491773.
      Citations: 53     Fields:    Translation:AnimalsCells
    185. Xue S, Jaszewski A, Perlman S. Identification of a CD4+ T cell epitope within the M protein of a neurotropic coronavirus. Virology. 1995 Apr 01; 208(1):173-9. PMID: 11831697.
      Citations: 18     Fields:    Translation:AnimalsCells
    186. Sun N, Perlman S. Spread of a neurotropic coronavirus to spinal cord white matter via neurons and astrocytes. J Virol. 1995 Feb; 69(2):633-41. PMID: 7815526.
      Citations: 20     Fields:    Translation:AnimalsCells
    187. Perlman S, Sun N, Barnett EM. Spread of MHV-JHM from nasal cavity to white matter of spinal cord. Transneuronal movement and involvement of astrocytes. Adv Exp Med Biol. 1995; 380:73-8. PMID: 8830549.
      Citations: 5     Fields:    Translation:AnimalsCells
    188. Chung S, Gorczynski R, Cruz B, Fingerote R, Skamene E, Perlman S, Leibowitz J, Fung L, Flowers M, Levy G. A Th1 cell line (3E9.1) from resistant A/J mice inhibits induction of macrophage procoagulant activity in vitro and protects against MHV-3 mortality in vivo. Immunology. 1994 Nov; 83(3):353-61. PMID: 7835959.
      Citations: 7     Fields:    Translation:AnimalsCells
    189. Castro RF, Evans GD, Evans GD, Jaszewski A, Perlman S. Coronavirus-induced demyelination occurs in the presence of virus-specific cytotoxic T cells. Virology. 1994 May 01; 200(2):733-43. PMID: 8178457.
      Citations: 22     Fields:    Translation:AnimalsCells
    190. Barnett EM, Perlman S. The olfactory nerve and not the trigeminal nerve is the major site of CNS entry for mouse hepatitis virus, strain JHM. Virology. 1993 May; 194(1):185-91. PMID: 8386871.
      Citations: 29     Fields:    Translation:AnimalsCells
    191. Oleszak EL, Perlman S, Parr R, Collisson EW, Leibowitz JL. Molecular mimicry between S peplomer proteins of coronaviruses (MHV, BCV, TGEV and IBV) and Fc receptor. Adv Exp Med Biol. 1993; 342:183-8. PMID: 8209728.
      Citations: 3     Fields:    Translation:AnimalsCells
    192. Chung S, Li C, Fung LS, Crow A, Gorczynski R, Cole E, Perlman S, Leibowitz J, Levy G. Role of macrophage procoagulant activity in mouse hepatitis virus (MHV) infection: studies using T cell MHV-3 clones and monoclonal antibody 3D4.3. Adv Exp Med Biol. 1993; 342:377-84. PMID: 8209757.
      Citations:    Fields:    Translation:AnimalsCells
    193. Perlman S, Barnett E, Jacobsen G. Mouse hepatitis virus and herpes simplex virus move along different CNS pathways. Adv Exp Med Biol. 1993; 342:313-8. PMID: 7516106.
      Citations: 4     Fields:    Translation:AnimalsCells
    194. Gallagher TM, Buchmeier MJ, Perlman S, Perlman S. Cell receptor-independent infection by a neurotropic murine coronavirus. Virology. 1992 Nov; 191(1):517-22. PMID: 1413526.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    195. Denison MR, Zoltick PW, Hughes SA, Giangreco B, Olson AL, Perlman S, Leibowitz JL, Weiss SR. Intracellular processing of the N-terminal ORF 1a proteins of the coronavirus MHV-A59 requires multiple proteolytic events. Virology. 1992 Jul; 189(1):274-84. PMID: 1318604.
      Citations: 43     Fields:    Translation:Cells
    196. Mobley J, Evans G, Evans G, Evans G, Dailey MO, Perlman S, Perlman S. Immune response to a murine coronavirus: identification of a homing receptor-negative CD4+ T cell subset that responds to viral glycoproteins. Virology. 1992 Apr; 187(2):443-52. PMID: 1347668.
      Citations: 12     Fields:    Translation:AnimalsCells
    197. Oleszak EL, Perlman S, Leibowitz JL. MHV S peplomer protein expressed by a recombinant vaccinia virus vector exhibits IgG Fc-receptor activity. Virology. 1992 Jan; 186(1):122-32. PMID: 1309271.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    198. Perlman S, Evans G, Evans G, Afifi A. Effect of olfactory bulb ablation on spread of a neurotropic coronavirus into the mouse brain. J Exp Med. 1990 Oct 01; 172(4):1127-32. PMID: 1698910.
      Citations: 41     Fields:    Translation:AnimalsCells
    199. Perlman S, Jacobsen G, Olson AL, Afifi A. Identification of the spinal cord as a major site of persistence during chronic infection with a murine coronavirus. Virology. 1990 Apr; 175(2):418-26. PMID: 2158180.
      Citations: 27     Fields:    Translation:AnimalsCells
    200. Jacobsen G, Perlman S. Localization of virus and antibody response in mice infected persistently with MHV-JHM. Adv Exp Med Biol. 1990; 276:573-8. PMID: 1966451.
      Citations: 5     Fields:    Translation:AnimalsCells
    201. Perlman S, Jacobsen G, Afifi A. Spread of a neurotropic murine coronavirus into the CNS via the trigeminal and olfactory nerves. Virology. 1989 Jun; 170(2):556-60. PMID: 2543129.
      Citations: 23     Fields:    Translation:AnimalsCells
    202. Perlman S, Perlman S, Jacobsen G, Jacobsen G, Moore S, Moore S. Regional localization of virus in the central nervous system of mice persistently infected with murine coronavirus JHM. Virology. 1988 Oct; 166(2):328-38. PMID: 2845647.
      Citations: 7     Fields:    Translation:AnimalsCells
    203. Leibowitz JL, Perlman S, Perlman S, Weinstock G, Weinstock G, DeVries JR, Budzilowicz C, Weissemann JM, Weiss SR, Weiss SR. Detection of a murine coronavirus nonstructural protein encoded in a downstream open reading frame. Virology. 1988 May; 164(1):156-64. PMID: 2834866.
      Citations: 17     Fields:    Translation:Cells
    204. Perlman S, Ries D. The astrocyte is a target cell in mice persistently infected with mouse hepatitis virus, strain JHM. Microb Pathog. 1987 Oct; 3(4):309-14. PMID: 2849022.
      Citations: 22     Fields:    Translation:AnimalsCells
    205. Denison M, Perlman S. Identification of putative polymerase gene product in cells infected with murine coronavirus A59. Virology. 1987 Apr; 157(2):565-8. PMID: 3029990.
      Citations: 28     Fields:    Translation:AnimalsCells
    206. Perlman S, Schelper R, Bolger E, Ries D. Late onset, symptomatic, demyelinating encephalomyelitis in mice infected with MHV-JHM in the presence of maternal antibody. Microb Pathog. 1987 Mar; 2(3):185-94. PMID: 2853274.
      Citations: 42     Fields:    Translation:AnimalsPHPublic Health
    207. Denison M, Perlman S. Translation and processing of MHV-A59 virion RNA in reticulocyte lysates and infected cells. Adv Exp Med Biol. 1987; 218:155-6. PMID: 2829524.
      Citations: 2     Fields:    Translation:AnimalsCells
    208. Perlman S, Schelper R, Ries D. Maternal antibody-modulated MHV-JHM infection in C57BL/6 and BALB/c mice. Adv Exp Med Biol. 1987; 218:297-305. PMID: 2829543.
      Citations: 6     Fields:    Translation:AnimalsCells
    209. Perlman S, Perlman S, Ries D, Bolger E, Chang LJ, Chang LJ, Stoltzfus CM. MHV nucleocapsid synthesis in the presence of cycloheximide and accumulation of negative strand MHV RNA. Virus Res. 1986 Dec; 6(3):261-72. PMID: 3033933.
      Citations: 10     Fields:    Translation:Cells
    210. Denison MR, Perlman S. Translation and processing of mouse hepatitis virus virion RNA in a cell-free system. J Virol. 1986 Oct; 60(1):12-8. PMID: 3018279.
      Citations: 35     Fields:    Translation:AnimalsCells
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