Minimal Clinically Important Difference
"Minimal Clinically Important Difference" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A statistically significant minimum set of clinical outcomes that demonstrates a clinical benefit of an intervention or treatment.
Descriptor ID |
D000071081
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MeSH Number(s) |
N04.761.559.590.399.750 N05.715.360.575.575.399.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Minimal Clinically Important Difference".
Below are MeSH descriptors whose meaning is more specific than "Minimal Clinically Important Difference".
This graph shows the total number of publications written about "Minimal Clinically Important Difference" by people in this website by year, and whether "Minimal Clinically Important Difference" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 1 | 2 |
2018 | 3 | 2 | 5 |
2019 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Minimal Clinically Important Difference" by people in Profiles.
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Doxycycline for community treatment of suspected COVID-19 in people at high risk of adverse outcomes in the UK (PRINCIPLE): a randomised, controlled, open-label, adaptive platform trial. Lancet Respir Med. 2021 09; 9(9):1010-1020.
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Validity of the 6-Minute Walk Test in Patients with End-Stage Lung Diseases Wearing an Oronasal Surgical Mask in Times of the COVID-19 Pandemic. Respiration. 2021; 100(7):594-599.
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Effect of filgotinib on health-related quality of life in active psoriatic arthritis: a randomized phase 2 trial (EQUATOR). Rheumatology (Oxford). 2020 07 01; 59(7):1495-1504.
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Comparative Effectiveness of Cartilage Repair With Respect to the Minimal Clinically Important Difference. Am J Sports Med. 2019 11; 47(13):3284-3293.
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Determining the minimal clinically important difference for the PEmbQoL questionnaire, a measure of pulmonary embolism-specific quality of life. J Thromb Haemost. 2018 12; 16(12):2454-2461.
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Determination of the minimally important difference (MID) in multi-biomarker disease activity (MBDA) test scores: impact of diurnal and daily biomarker variation patterns on MBDA scores. Clin Rheumatol. 2019 Feb; 38(2):437-445.
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Minimal clinically important differences for measures of treatment efficacy in Stevens-Johnson syndrome and toxic epidermal necrolysis. J Am Acad Dermatol. 2018 Dec; 79(6):1150-1152.
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Patient acceptable symptom state and minimal clinically important difference for patient-reported outcomes in systemic sclerosis: A secondary analysis of a randomized controlled trial comparing personalized physical therapy to usual care. Semin Arthritis Rheum. 2019 02; 48(4):694-700.
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The minimal clinically important difference of the Richmond Agitation-Sedation Scale in patients with cancer with agitated delirium. Cancer. 2018 05 15; 124(10):2246-2252.
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An Assessment in SpondyloArthritis International Society (ASAS)-endorsed definition of clinically important worsening in axial spondyloarthritis based on ASDAS. Ann Rheum Dis. 2018 Jan; 77(1):124-127.