"Superoxide Dismutase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.
| Descriptor ID |
D000072105
|
| MeSH Number(s) |
D08.811.682.881.500
|
| Concept/Terms |
Superoxide Dismutase-1- Superoxide Dismutase-1
- Cuprozinc Superoxide Dismutase
- Superoxide Dismutase, Cuprozinc
- Superoxide Dismutase 1
- Cu-Zn Superoxide Dismutase
- Cu Zn Superoxide Dismutase
- Superoxide Dismutase, Cu-Zn
- SOD-1 Protein
- SOD 1 Protein
- SOD1 Protein
|
Below are MeSH descriptors whose meaning is more general than "Superoxide Dismutase-1".
Below are MeSH descriptors whose meaning is more specific than "Superoxide Dismutase-1".
This graph shows the total number of publications written about "Superoxide Dismutase-1" by people in this website by year, and whether "Superoxide Dismutase-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 3 | 5 |
| 2018 | 2 | 3 | 5 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Superoxide Dismutase-1" by people in Profiles.
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Novel Selenium-based compounds with therapeutic potential for SOD1-linked amyotrophic lateral sclerosis. EBioMedicine. 2020 Sep; 59:102980.
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Impact of Pharmacological Inhibition of Hydrogen Sulphide Production in the SOD1G93A-ALS Mouse Model. Int J Mol Sci. 2019 May 24; 20(10).
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Network mapping of the conformational heterogeneity of SOD1 by deploying statistical cluster analysis of FTIR spectra. Cell Mol Life Sci. 2019 Oct; 76(20):4145-4154.
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MicroRNA-199a-3p and MicroRNA-199a-5p Take Part to a Redundant Network of Regulation of the NOS (NO Synthase)/NO Pathway in the Endothelium. Arterioscler Thromb Vasc Biol. 2018 10; 38(10):2345-2357.
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Epigenetic Changes Associated with the Expression of Amyotrophic Lateral Sclerosis (ALS) Causing Genes. Neuroscience. 2018 10 15; 390:1-11.
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TFE-induced local unfolding and fibrillation of SOD1: bridging the experiment and simulation studies. Biochem J. 2018 05 18; 475(10):1701-1719.
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Randomized, double-blind, placebo-controlled trial of arimoclomol in rapidly progressive SOD1 ALS. Neurology. 2018 02 13; 90(7):e565-e574.
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Unraveling ALS due to SOD1 mutation through the combination of brain and cervical cord MRI. Neurology. 2018 02 20; 90(8):e707-e716.
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Short-term sustained hyperglycaemia fosters an archetypal senescence-associated secretory phenotype in endothelial cells and macrophages. Redox Biol. 2018 05; 15:170-181.
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Computing disease-linked SOD1 mutations: deciphering protein stability and patient-phenotype relations. Sci Rep. 2017 07 05; 7(1):4678.