"Fibromodulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A small leucine-rich proteoglycan that contains 4 KERATAN SULFATE chains within the leucine repeat region. It interacts with COLLAGEN TYPE I and COLLAGEN TYPE II fibrils and may function to control the rate of EXTRACELLULAR MATRIX assembly. It also sequesters TRANSFORMING GROWTH FACTOR BETA in the extracellular matrix.
| Descriptor ID |
D000071235
|
| MeSH Number(s) |
D09.698.735.700.813 D12.776.395.650.875.625 D12.776.860.300.806.813
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Fibromodulin".
Below are MeSH descriptors whose meaning is more specific than "Fibromodulin".
This graph shows the total number of publications written about "Fibromodulin" by people in this website by year, and whether "Fibromodulin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Fibromodulin" by people in Profiles.
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Downregulated microRNA-340-5p promotes proliferation and inhibits apoptosis of chondrocytes in osteoarthritis mice through inhibiting the extracellular signal-regulated kinase signaling pathway by negatively targeting the FMOD gene. J Cell Physiol. 2018 01; 234(1):927-939.