Prostaglandin-E Synthases
"Prostaglandin-E Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Oxidoreductases that catalyze the GLUTATHIONE-dependent oxidoreduction of PROSTAGLANDIN H2 to PROSTAGLANDIN E2.
| Descriptor ID |
D000071876
|
| MeSH Number(s) |
D08.811.399.475.600
|
| Concept/Terms |
Prostaglandin-E Synthases- Prostaglandin-E Synthases
- Synthases, Prostaglandin-E
- Prostaglandin E Synthases
- E Synthases, Prostaglandin
- Synthases, Prostaglandin E
Prostaglandin-E Synthase- Prostaglandin-E Synthase
- Synthase, Prostaglandin-E
- PGE2 Synthase
- Synthase, PGE2
- PGR2 E-Isomerase
- PGR2 E Isomerase
- Endoperoxide Isomerase
- Isomerase, Endoperoxide
- Prostaglandin E Isomerase
- Isomerase, Prostaglandin E
- Prostaglandin E Synthase-1
- Prostaglandin E2 Synthase
- Synthase, Prostaglandin E2
- Prostaglandin H2 E-Isomerase
- Prostaglandin H2 E Isomerase
- Prostaglandin H2-Prostaglandin E2 Isomerase
- Prostaglandin H2 Prostaglandin E2 Isomerase
- Prostaglandin R2 E-Isomerase
- Prostaglandin R2 E Isomerase
- Prostaglandin Endoperoxide E Isomerase
- Prostaglandin E Synthase 1
- PGE2 Isomerase
- Isomerase, PGE2
- Prostaglandin E Synthase
- Synthase, Prostaglandin E
|
Below are MeSH descriptors whose meaning is more general than "Prostaglandin-E Synthases".
Below are MeSH descriptors whose meaning is more specific than "Prostaglandin-E Synthases".
This graph shows the total number of publications written about "Prostaglandin-E Synthases" by people in this website by year, and whether "Prostaglandin-E Synthases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 3 | 1 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Prostaglandin-E Synthases" by people in Profiles.
-
What about COVID-19 and arachidonic acid pathway? Eur J Clin Pharmacol. 2020 Nov; 76(11):1501-1504.
-
DREAM-in-CDM Approach and Identification of a New Generation of Anti-inflammatory Drugs Targeting mPGES-1. Sci Rep. 2020 06 23; 10(1):10187.
-
In Silico Observation of the Conformational Opening of the Glutathione-Binding Site of Microsomal Prostaglandin E2 Synthase-1. J Chem Inf Model. 2019 09 23; 59(9):3839-3845.
-
Regulation of YAP by Mammalian Target of Rapamycin Complex 1 in Endothelial Cells Controls Blood Pressure Through COX-2/mPGES-1/PGE2 Cascade. Hypertension. 2019 10; 74(4):936-946.
-
Inhibition of COX-2/mPGES-1 and 5-LOX in macrophages by leonurine ameliorates monosodium urate crystal-induced inflammation. Toxicol Appl Pharmacol. 2018 07 15; 351:1-11.
-
Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs. Sci Rep. 2018 03 26; 8(1):5205.
-
Impaired lipid metabolism markers to assess the risk of neuroinflammation in autism spectrum disorder. Metab Brain Dis. 2018 08; 33(4):1141-1153.
-
Design, synthesis, and discovery of 5-((1,3-diphenyl-1H-pyrazol-4-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones and related derivatives as novel inhibitors of mPGES-1. Bioorg Med Chem Lett. 2018 03 01; 28(5):858-862.
-
Plant-derived mPGES-1 inhibitors or suppressors: A new emerging trend in the search for small molecules to combat inflammation. Eur J Med Chem. 2018 Jun 10; 153:2-28.
-
Selective inhibitors of human mPGES-1 from structure-based computational screening. Bioorg Med Chem Lett. 2017 08 15; 27(16):3739-3743.