Sodium-Hydrogen Exchanger 1
"Sodium-Hydrogen Exchanger 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-hydrogen antiporter expressed by many cell types, especially on the basolateral surfaces of EPITHELIAL CELLS. It functions through an inward sodium ion chemical gradient to eliminate acids (protons) generated by metabolism and regulate intracellular pH. It is highly sensitive to AMILORIDE.
| Descriptor ID |
D000074082
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| MeSH Number(s) |
D12.776.157.530.450.162.775.500 D12.776.157.530.937.703.500 D12.776.543.550.190.775.500 D12.776.543.585.450.162.775.500 D12.776.543.585.937.828.500
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| Concept/Terms |
Sodium-Hydrogen Exchanger 1- Sodium-Hydrogen Exchanger 1
- Sodium Hydrogen Exchanger 1
- SLC9A1 Protein
- Na(+)-H(+) Exchanger 1
- Solute Carrier Family 9 Member 1
|
Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchanger 1".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchanger 1".
This graph shows the total number of publications written about "Sodium-Hydrogen Exchanger 1" by people in this website by year, and whether "Sodium-Hydrogen Exchanger 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2018 | 2 | 0 | 2 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Hydrogen Exchanger 1" by people in Profiles.
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Decreased GLUT1/NHE1 RNA expression in whole blood predicts disease severity in patients with COVID-19. ESC Heart Fail. 2021 02; 8(1):309-316.
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Amorphous nano-selenium quantum dots improve endothelial dysfunction in rats and prevent atherosclerosis in mice through Na+/H+ exchanger 1 inhibition. Vascul Pharmacol. 2019 04; 115:26-32.
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Amelioration of Lipopolysaccharide-Induced Acute Lung Injury in Rats by Na-H Exchanger-1 Inhibitor Amiloride Is Associated with Reversal of ERK Mitogen-Activated Protein Kinase. Biomed Res Int. 2018; 2018:3560234.
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Diverse residues of intracellular loop 5 of the Na+/H+ exchanger modulate proton sensing, expression, activity and targeting. Biochim Biophys Acta Biomembr. 2019 01; 1861(1):191-200.
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Inhibition of carbonic anhydrase prevents the Na(+)/H(+) exchanger 1-dependent slow force response to rat myocardial stretch. Am J Physiol Heart Circ Physiol. 2013 Jul 15; 305(2):H228-37.