"alpha-Macroglobulins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins with a molecular weight of approximately 620,000 to 680,000. Precipitation by electrophoresis is in the alpha region. They include alpha 1-macroglobulins and alpha 2-macroglobulins. These proteins exhibit trypsin-, chymotrypsin-, thrombin-, and plasmin-binding activity and function as hormonal transporters.
| Descriptor ID |
D000511
|
| MeSH Number(s) |
D12.776.124.050.080 D12.776.124.790.106.100 D12.776.124.790.720.100 D12.776.377.715.085.100 D12.776.377.715.647.100
|
| Concept/Terms |
alpha-Macroglobulins- alpha-Macroglobulins
- alpha Macroglobulins
- 45S RNP
- RNP, 45S
- alpha-Macrofetoproteins
- alpha Macrofetoproteins
Slow alpha 2-Macroglobulins- Slow alpha 2-Macroglobulins
- Slow alpha 2 Macroglobulins
- alpha 2-Macroglobulins, Slow
- Slow alpha 2-Globulin
- Slow alpha 2 Globulin
- alpha 2-Globulin, Slow
alpha 1-Acute Phase Protein- alpha 1-Acute Phase Protein
- alpha 1 Acute Phase Protein
- Acute-Phase alpha 1-Protein
- Acute Phase alpha 1 Protein
- alpha 1-Protein, Acute-Phase
|
Below are MeSH descriptors whose meaning is more general than "alpha-Macroglobulins".
Below are MeSH descriptors whose meaning is more specific than "alpha-Macroglobulins".
This graph shows the total number of publications written about "alpha-Macroglobulins" by people in this website by year, and whether "alpha-Macroglobulins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2018 | 1 | 2 | 3 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "alpha-Macroglobulins" by people in Profiles.
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Thromboinflammation in COVID-19: Can a2 -macroglobulin help to control the fire? J Thromb Haemost. 2021 Feb; 19(2):351-354.
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A new suggested approach in screening for Bence Jones protein and potential kidney damage. Clin Chem Lab Med. 2019 03 26; 57(4):e54-e56.
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Validation of Serum Test for Advanced Liver Fibrosis in Patients With Nonalcoholic Steatohepatitis. Clin Gastroenterol Hepatol. 2019 08; 17(9):1867-1876.e3.
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Microvesicle Subsets in Sepsis Due to Community Acquired Pneumonia Compared to Faecal Peritonitis. Shock. 2018 04; 49(4):393-401.
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Integrating Functional Analysis in the Next-Generation Sequencing Diagnostic Pipeline of RASopathies. Sci Rep. 2018 02 05; 8(1):2421.
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B-cell polyclonal activation and Epstein-Barr viral abortive lytic cycle are two key features in acute infectious mononucleosis. J Clin Virol. 2011 Sep; 52(1):33-7.
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LTB4 increases nasal neutrophil activity and conditions neutrophils to exert antiviral effects. Respir Med. 2011 Jul; 105(7):997-1006.
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Effects of T-2 toxin and selenium on chondrocyte expression of matrix metalloproteinases (MMP-1, MMP-13), a2-macroglobulin (a2M) and TIMPs. Toxicol In Vitro. 2011 Mar; 25(2):492-9.
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An efficient method to make human monoclonal antibodies from memory B cells: potent neutralization of SARS coronavirus. Nat Med. 2004 Aug; 10(8):871-5.
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Tetranucleotide length polymorphism 5' of the alpha 2-macroglobulin receptor (A2MR)/LDL receptor-related protein (LRP) gene. Hum Mol Genet. 1994 Jan; 3(1):215.