"Tiotropium Bromide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A scopolamine derivative and CHOLINERGIC ANTAGONIST that functions as a BRONCHODILATOR AGENT. It is used in the treatment of CHRONIC OBSTRUCTIVE PULMONARY DISEASE.
| Descriptor ID |
D000069447
|
| MeSH Number(s) |
D02.145.074.722.822.887 D03.132.889.601.887 D03.605.084.500.722.822.887 D03.605.869.822.887
|
| Concept/Terms |
Tiotropium Bromide- Tiotropium Bromide
- Bromide, Tiotropium
- 7-((hydroxybis(2-thienyl)acetyl)oxy)-9,9-dimethyl-3-oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane bromide
BA 679 BR- BA 679 BR
- 679 BR, BA
- BR, BA 679
- BA-679 BR
- BA679 BR
|
Below are MeSH descriptors whose meaning is more general than "Tiotropium Bromide".
Below are MeSH descriptors whose meaning is more specific than "Tiotropium Bromide".
This graph shows the total number of publications written about "Tiotropium Bromide" by people in this website by year, and whether "Tiotropium Bromide" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 7 | 3 | 10 |
| 2018 | 6 | 3 | 9 |
| 2019 | 2 | 1 | 3 |
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Below are the most recent publications written about "Tiotropium Bromide" by people in Profiles.
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Two cases of chronic obstructive pulmonary disease evaluated by dynamic-ventilatory digital radiography for pulmonary function and assessment of treatment efficacy. Respir Investig. 2021 Nov; 59(6):871-875.
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Tiotropium is Predicted to be a Promising Drug for COVID-19 Through Transcriptome-Based Comprehensive Molecular Pathway Analysis. Viruses. 2020 07 20; 12(7).
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How Should We Treat Patients with Mild Asthma? N Engl J Med. 2019 05 23; 380(21):2064-2066.
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Inhaled Glucocorticoid with or without Tiotropium Bromide for Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome. J Coll Physicians Surg Pak. 2019 Mar; 29(3):249-252.
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Effects of baseline symptom burden on treatment response in COPD. Int J Chron Obstruct Pulmon Dis. 2019; 14:181-194.
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Spirometric changes during exacerbations of COPD: a post hoc analysis of the WISDOM trial. Respir Res. 2018 Dec 13; 19(1):251.
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The short-term bronchodilator effects of the dual phosphodiesterase 3 and 4 inhibitor RPL554 in COPD. Eur Respir J. 2018 11; 52(5).
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The pharmacokinetics, pharmacodynamics and tolerability of PUR0200, a novel tiotropium formulation, in chronic obstructive pulmonary disease. Br J Clin Pharmacol. 2018 09; 84(9):2097-2105.
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Tiotropium could provide benefits in the early stage of COPD, but further studies are needed. BMJ Evid Based Med. 2018 10; 23(5):183-184.
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Tiotropium inhibits methacholine-induced extracellular matrix production via ß-catenin signaling in human airway smooth muscle cells. Int J Chron Obstruct Pulmon Dis. 2018; 13:1469-1481.