Receptor for Advanced Glycation End Products
"Receptor for Advanced Glycation End Products" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A single-pass transmembrane CELL SURFACE RECEPTOR that binds ADVANCED GLYCATION END PRODUCTS to mediate cellular responses to both acute and chronic vascular inflammation in conditions such as ATHEROSCLEROSIS and DIABETES MELLITUS, TYPE 2. It also binds AMYLOID BETA PEPTIDES and the ALARMINS - S100A12 and S100 CALCIUM BINDING PROTEIN BETA SUBUNIT.
| Descriptor ID |
D000067759
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| MeSH Number(s) |
D12.776.543.750.615
|
| Concept/Terms |
Receptor for Advanced Glycation End Products- Receptor for Advanced Glycation End Products
- AGE Receptor
- Receptor, AGE
- RAGE (Receptor for Advanced Glycation End Products)
- Advanced Glycosylation End Product Receptors
- Advanced Glycosylation End-Product Receptor
- Advanced Glycosylation End Product Receptor
- Advanced Glycosylation End-Product Receptors
- Advanced Glycosylation Endproduct Receptors
- Receptor for Advanced Glycation End Products (RAGE)
- Receptor for Advanced Glycation Endproducts
- Receptor, Advanced Glycosylation End-Product
- Receptor, Advanced Glycosylation End Product
- Receptor, Advanced Glycosylation End-Products
- Receptor, Advanced Glycosylation End Products
- Advanced Glycosylation End Product-Specific Receptor
- Advanced Glycosylation End Product Specific Receptor
- AGER Protein
- Protein, AGER
- Amphoterin Receptor
- Receptor, Amphoterin
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Below are MeSH descriptors whose meaning is more general than "Receptor for Advanced Glycation End Products".
Below are MeSH descriptors whose meaning is more specific than "Receptor for Advanced Glycation End Products".
This graph shows the total number of publications written about "Receptor for Advanced Glycation End Products" by people in this website by year, and whether "Receptor for Advanced Glycation End Products" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 7 | 4 | 11 |
| 2018 | 11 | 4 | 15 |
| 2019 | 5 | 3 | 8 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor for Advanced Glycation End Products" by people in Profiles.
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Age, obesity and hyperglycaemia: Activation of innate immunity initiates a series of molecular interactions involving anionic surfaces leading to COVID-19 morbidity and mortality. Med Hypotheses. 2021 Oct; 155:110646.
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Importance of Lung Epithelial Injury in COVID-19-associated Acute Respiratory Distress Syndrome: Value of Plasma Soluble Receptor for Advanced Glycation End-Products. Am J Respir Crit Care Med. 2021 08 01; 204(3):359-362.
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Endothelial Cell Participation in Inflammatory Reaction. Int J Mol Sci. 2021 Jun 13; 22(12).
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Hyperactivated RAGE in Comorbidities as a Risk Factor for Severe COVID-19-The Role of RAGE-RAS Crosstalk. Biomolecules. 2021 06 12; 11(6).
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Advanced glycation end products (AGEs) and its receptor, RAGE, modulate age-dependent COVID-19 morbidity and mortality. A review and hypothesis. Int Immunopharmacol. 2021 Sep; 98:107806.
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Receptor for advanced glycation end-products axis and coronavirus disease 2019 in inflammatory bowel diseases: A dangerous liaison? World J Gastroenterol. 2021 May 21; 27(19):2270-2280.
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SARS-CoV-2 proteins regulate inflammatory, thrombotic and diabetic responses in human arterial fibroblasts. Clin Immunol. 2021 06; 227:108733.
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Targeting RAGE to prevent SARS-CoV-2-mediated multiple organ failure: Hypotheses and perspectives. Life Sci. 2021 May 01; 272:119251.
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Journey to a Receptor for Advanced Glycation End Products Connection in Severe Acute Respiratory Syndrome Coronavirus 2 Infection: With Stops Along the Way in the Lung, Heart, Blood Vessels, and Adipose Tissue. Arterioscler Thromb Vasc Biol. 2021 02; 41(2):614-627.
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COVID-19 and Diabetes: The Importance of Controlling RAGE. Front Endocrinol (Lausanne). 2020; 11:526.