"Pyroptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Type of programmed cell death associated with infection by intracellular pathogens. It is characterized by INFLAMMASOME formation; activation of CASPASE 1; and CYTOKINES mediated inflammation.
| Descriptor ID |
D000069292
|
| MeSH Number(s) |
G04.146.160.530
|
| Concept/Terms |
Pyroptosis- Pyroptosis
- Pyroptoses
- Pyroptotic Cell Death
- Cell Death, Pyroptotic
- Cell Deaths, Pyroptotic
- Death, Pyroptotic Cell
- Deaths, Pyroptotic Cell
- Pyroptotic Cell Deaths
- Inflammatory Apoptosis
- Apoptoses, Inflammatory
- Apoptosis, Inflammatory
- Inflammatory Apoptoses
- Caspase-1 Dependent Cell Death
- Caspase 1 Dependent Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Pyroptosis".
Below are MeSH descriptors whose meaning is more specific than "Pyroptosis".
This graph shows the total number of publications written about "Pyroptosis" by people in this website by year, and whether "Pyroptosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 2 | 2 | 4 |
| 2018 | 5 | 0 | 5 |
| 2019 | 2 | 1 | 3 |
| 2020 | 2 | 1 | 3 |
| 2021 | 2 | 3 | 5 |
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Below are the most recent publications written about "Pyroptosis" by people in Profiles.
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Endothelium-protective, histone-neutralizing properties of the polyanionic agent defibrotide. JCI Insight. 2021 09 08; 6(17).
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FNDC4 and FNDC5 reduce SARS-CoV-2 entry points and spike glycoprotein S1-induced pyroptosis, apoptosis, and necroptosis in human adipocytes. Cell Mol Immunol. 2021 10; 18(10):2457-2459.
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Inflammasome activation at the crux of severe COVID-19. Nat Rev Immunol. 2021 11; 21(11):694-703.
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SARS-CoV-2 nucleocapsid suppresses host pyroptosis by blocking Gasdermin D cleavage. EMBO J. 2021 09 15; 40(18):e108249.
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Single-Cell Transcriptomic Profiling of MAIT Cells in Patients With COVID-19. Front Immunol. 2021; 12:700152.
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SARS-CoV-2 may trigger inflammasome and pyroptosis in the central nervous system: a mechanistic view of neurotropism. Inflammopharmacology. 2021 Aug; 29(4):1049-1059.
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An evidence that SARS-Cov-2/COVID-19 spike protein (SP) damages hematopoietic stem/progenitor cells in the mechanism of pyroptosis in Nlrp3 inflammasome-dependent manner. Leukemia. 2021 10; 35(10):3026-3029.
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Unknown/enigmatic functions of extracellular ASC. Immunology. 2021 08; 163(4):377-388.
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Activation of Interleukin-1ß Release and Pyroptosis by Transmissible Gastroenteritis Virus Is Dependent on the NOD-Like Receptor Protein 3 Inflammasome in Porcine Intestinal Epithelial Cell Line. Viral Immunol. 2021 Jul-Aug; 34(6):401-409.
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Pyroptotic macrophages stimulate the SARS-CoV-2-associated cytokine storm. Cell Mol Immunol. 2021 05; 18(5):1305-1307.