"APOBEC Deaminases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of conserved cytidine deaminases that catalyze the DEAMINATION of CYTIDINE to URIDINE. They are characterized by N and C-terminal zinc-dependent catalytic domains and have important functions in RNA EDITING; EPIGENTIC PROCESSES; and the INNATE IMMUNE RESPONSE against viruses.
| Descriptor ID |
D000071478
|
| MeSH Number(s) |
D08.811.277.151.486.250.500
|
| Concept/Terms |
APOBEC Deaminases- APOBEC Deaminases
- Deaminases, APOBEC
- APOBEC Family Proteins
- APOBEC Enzymes
- Apolipoprotein B mRNA Editing Enzyme, Catalytic Polypeptides
- AID-APOBEC Deaminases
- AID APOBEC Deaminases
- Deaminases, AID-APOBEC
|
Below are MeSH descriptors whose meaning is more general than "APOBEC Deaminases".
Below are MeSH descriptors whose meaning is more specific than "APOBEC Deaminases".
This graph shows the total number of publications written about "APOBEC Deaminases" by people in this website by year, and whether "APOBEC Deaminases" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 2 | 1 | 3 |
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Below are the most recent publications written about "APOBEC Deaminases" by people in Profiles.
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Extensive C->U transition biases in the genomes of a wide range of mammalian RNA viruses; potential associations with transcriptional mutations, damage- or host-mediated editing of viral RNA. PLoS Pathog. 2021 06; 17(6):e1009596.
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Mutational Asymmetries in the SARS-CoV-2 Genome May Lead to Increased Hydrophobicity of Virus Proteins. Genes (Basel). 2021 05 27; 12(6).
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The role of A-to-I RNA editing in infections by RNA viruses: Possible implications for SARS-CoV-2 infection. Clin Immunol. 2021 05; 226:108699.
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RNA editors: key regulators of viral response in cancer patients. Epigenomics. 2021 02; 13(3):165-167.
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Potential APOBEC-mediated RNA editing of the genomes of SARS-CoV-2 and other coronaviruses and its impact on their longer term evolution. Virology. 2021 04; 556:62-72.
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Coronavirus genomes carry the signatures of their habitats. PLoS One. 2020; 15(12):e0244025.
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[APOBEC3s: history of an antiviral and mutagenic protein family]. Virologie (Montrouge). 2020 12 01; 24(6):381-418.
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Host-directed editing of the SARS-CoV-2 genome. Biochem Biophys Res Commun. 2021 01 29; 538:35-39.
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Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses. Sci Rep. 2020 10 20; 10(1):17766.
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Footprint of the host restriction factors APOBEC3 on the genome of human viruses. PLoS Pathog. 2020 08; 16(8):e1008718.