Adenosine Diphosphate Ribose
"Adenosine Diphosphate Ribose" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ester formed between the aldehydic carbon of RIBOSE and the terminal phosphate of ADENOSINE DIPHOSPHATE. It is produced by the hydrolysis of nicotinamide-adenine dinucleotide (NAD) by a variety of enzymes, some of which transfer an ADP-ribosyl group to target proteins.
| Descriptor ID |
D000246
|
| MeSH Number(s) |
D03.633.100.759.646.138.124.070.125 D09.408.620.569.070.125 D13.695.667.138.124.070.125 D13.695.827.068.124.070.125 D13.695.827.708.070.125
|
| Concept/Terms |
Adenosine Diphosphate Ribose- Adenosine Diphosphate Ribose
- Diphosphate Ribose, Adenosine
- Ribose, Adenosine Diphosphate
- ADP-Ribose
- ADP Ribose
- Ribose, ADP
- ADPribose
- Adenosine 5'-Diphosphoribose
- 5'-Diphosphoribose, Adenosine
- Adenosine 5' Diphosphoribose
- Adenosine Diphosphoribose
- Diphosphoribose, Adenosine
|
Below are MeSH descriptors whose meaning is more general than "Adenosine Diphosphate Ribose".
Below are MeSH descriptors whose meaning is more specific than "Adenosine Diphosphate Ribose".
This graph shows the total number of publications written about "Adenosine Diphosphate Ribose" by people in this website by year, and whether "Adenosine Diphosphate Ribose" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Adenosine Diphosphate Ribose" by people in Profiles.
-
High-Throughput Screening and Quantum Mechanics for Identifying Potent Inhibitors Against Mac1 Domain of SARS-CoV-2 Nsp3. IEEE/ACM Trans Comput Biol Bioinform. 2021 Jul-Aug; 18(4):1262-1270.
-
Elucidating the tunability of binding behavior for the MERS-CoV macro domain with NAD metabolites. Commun Biol. 2021 01 27; 4(1):123.
-
The SARS-CoV-2 Conserved Macrodomain Is a Mono-ADP-Ribosylhydrolase. J Virol. 2021 01 13; 95(3).
-
ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4. Proc Natl Acad Sci U S A. 2021 01 12; 118(2).
-
ADPriboDB 2.0: an updated database of ADP-ribosylated proteins. Nucleic Acids Res. 2021 01 08; 49(D1):D261-D265.
-
Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential. Open Biol. 2020 11; 10(11):200237.
-
Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity. J Biol Chem. 2020 12 25; 295(52):17986-17996.
-
Structural, Biophysical, and Biochemical Elucidation of the SARS-CoV-2 Nonstructural Protein 3 Macro Domain. ACS Infect Dis. 2020 11 13; 6(11):2970-2978.
-
1H, 13C, and 15N backbone chemical shift assignments of the apo and the ADP-ribose bound forms of the macrodomain of SARS-CoV-2 non-structural protein 3b. Biomol NMR Assign. 2020 10; 14(2):339-346.
-
Molecular Basis for ADP-Ribose Binding to the Mac1 Domain of SARS-CoV-2 nsp3. Biochemistry. 2020 07 21; 59(28):2608-2615.