"Prion Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycosylphosphatidylinositol-anchored glycoproteins that may aggregate into rod-like structures. The prion protein (PRNP) gene is characterized by five TANDEM REPEAT SEQUENCES that encode a highly unstable protein region of five octapeptide repeats. Mutations in the repeat region and elsewhere in this gene are associated with CREUTZFELDT-JAKOB DISEASE; FATAL FAMILIAL INSOMNIA; GERSTMANN-STRAUSSLER DISEASE; Huntington disease-like 1, and KURU.
| Descriptor ID |
D000072002
|
| MeSH Number(s) |
D12.776.395.550.448.600 D12.776.543.484.500.625 D12.776.543.550.418.600 D12.776.785.340
|
| Concept/Terms |
Prion Proteins- Prion Proteins
- Prion Protein
- CD230 Antigen
- Antigen, CD230
- PrP Proteins
- Fatal Familial Insomnia Protein
- Major Prion Protein
- Prion Protein, Major
- Creutzfeldt-Jakob Disease Protein
- Creutzfeldt Jakob Disease Protein
|
Below are MeSH descriptors whose meaning is more general than "Prion Proteins".
Below are MeSH descriptors whose meaning is more specific than "Prion Proteins".
This graph shows the total number of publications written about "Prion Proteins" by people in this website by year, and whether "Prion Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 2 | 0 | 2 |
| 2019 | 2 | 1 | 3 |
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Below are the most recent publications written about "Prion Proteins" by people in Profiles.
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Are prion proteins and magnetite involved in the immune cells memory system connected to the covid-19? Med Hypotheses. 2021 05; 150:110563.
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Atypical clinical presentation of variant Creutzfeldt-Jakob disease. Eur J Anaesthesiol. 2019 09; 36(9):714-715.
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Plasma total prion protein as a potential biomarker for neurodegenerative dementia: diagnostic accuracy in the spectrum of prion diseases. Neuropathol Appl Neurobiol. 2020 04; 46(3):240-254.
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Cellular prion protein neither binds to alpha-synuclein oligomers nor mediates their detrimental effects. Brain. 2019 02 01; 142(2):249-254.
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Improved high-yield expression, purification and refolding of recombinant mammalian prion proteins under aerosol-free elevated biological safety conditions. Protein Expr Purif. 2018 10; 150:53-60.
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Structural and mechanistic aspects influencing the ADAM10-mediated shedding of the prion protein. Mol Neurodegener. 2018 04 06; 13(1):18.
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Diverse functions of the prion protein - Does proteolytic processing hold the key? Biochim Biophys Acta Mol Cell Res. 2017 Nov; 1864(11 Pt B):2128-2137.
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Amyloid- and FDG-PET in sporadic Creutzfeldt-Jakob disease: Correlation with pathological prion protein in neuropathology. Prion. 2017 05 04; 11(3):205-213.
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Cellular Prion Protein PrPC and Ecto-5'-Nucleotidase Are Markers of the Cellular Stress Response to Aneuploidy. Cancer Res. 2017 06 01; 77(11):2914-2926.
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Dementia-like pathology in type-2 diabetes: A novel microRNA mechanism. Mol Cell Neurosci. 2017 04; 80:58-65.