"Diosgenin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A spirostan found in DIOSCOREA and other plants. The 25S isomer is called yamogenin. Solasodine is a natural derivative formed by replacing the spiro-ring with a nitrogen, which can rearrange to SOLANINE.
Descriptor ID |
D004144
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MeSH Number(s) |
D04.210.500.247.515.500
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Diosgenin".
Below are MeSH descriptors whose meaning is more specific than "Diosgenin".
This graph shows the total number of publications written about "Diosgenin" by people in this website by year, and whether "Diosgenin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2014 | 1 | 0 | 1 |
2017 | 1 | 1 | 2 |
2018 | 3 | 0 | 3 |
2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Diosgenin" by people in Profiles.
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Methyl protodioscin from Polygonatum sibiricum inhibits cervical cancer through cell cycle arrest and apoptosis induction. Food Chem Toxicol. 2019 Oct; 132:110655.
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Polyphyllin I Inhibits Propionibacterium acnes-Induced Inflammation In Vitro. Inflammation. 2019 Feb; 42(1):35-44.
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Diosgenin inhibited the expression of TAZ in hepatocellular carcinoma. Biochem Biophys Res Commun. 2018 09 10; 503(3):1181-1185.
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Molecular mechanism and inhibitory targets of dioscin in HepG2 cells. Food Chem Toxicol. 2018 Oct; 120:143-154.
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Crosstalk of NF-?B/P65 and LncRNA HOTAIR-Mediated Repression of MUC1 Expression Contribute to Synergistic Inhibition of Castration-Resistant Prostate Cancer by Polyphyllin 1-Enzalutamide Combination Treatment. Cell Physiol Biochem. 2018; 47(2):759-773.
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Effect and mechanism of dioscin from Dioscorea spongiosa on uric acid excretion in animal model of hyperuricemia. J Ethnopharmacol. 2018 Mar 25; 214:29-36.
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(22ß,25R)-3ß-Hydroxy-spirost-5-en-7-iminoxy-heptanoic acid exhibits anti-prostate cancer activity through caspase pathway. Steroids. 2017 03; 119:43-52.
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Synthesis of diosgenin analogues as potential anti-inflammatory agents. J Steroid Biochem Mol Biol. 2014 Sep; 143:323-33.