"Genes, Immunoglobulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genes encoding the different subunits of the IMMUNOGLOBULINS, for example the IMMUNOGLOBULIN LIGHT CHAIN GENES and the IMMUNOGLOBULIN HEAVY CHAIN GENES. The heavy and light immunoglobulin genes are present as gene segments in the germline cells. The completed genes are created when the segments are shuffled and assembled (B-LYMPHOCYTE GENE REARRANGEMENT) during B-LYMPHOCYTE maturation. The gene segments of the human light and heavy chain germline genes are symbolized V (variable), J (joining) and C (constant). The heavy chain germline genes have an additional segment D (diversity).
| Descriptor ID |
D005803
|
| MeSH Number(s) |
G05.360.340.024.340.335 G12.500.299
|
| Concept/Terms |
Genes, Immunoglobulin- Genes, Immunoglobulin
- Immunoglobulin Genes
- Gene, Immunoglobulin
- Immunoglobulin Gene
- Genes, Ig
- Gene, Ig
- Ig Gene
- Ig Genes
|
Below are MeSH descriptors whose meaning is more general than "Genes, Immunoglobulin".
Below are MeSH descriptors whose meaning is more specific than "Genes, Immunoglobulin".
This graph shows the total number of publications written about "Genes, Immunoglobulin" by people in this website by year, and whether "Genes, Immunoglobulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 1 | 0 | 1 |
| 2004 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Genes, Immunoglobulin" by people in Profiles.
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Diverse immunoglobulin gene usage and convergent epitope targeting in neutralizing antibody responses to SARS-CoV-2. Cell Rep. 2021 05 11; 35(6):109109.
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Shared B cell memory to coronaviruses and other pathogens varies in human age groups and tissues. Science. 2021 05 14; 372(6543):738-741.
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B-Lymphocyte Phenotype Determines T-Lymphocyte Subset Differentiation in Autoimmune Diabetes. Front Immunol. 2019; 10:1732.
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Immunoglobulin Gene Sequence Analysis In Chronic Lymphocytic Leukemia: From Patient Material To Sequence Interpretation. J Vis Exp. 2018 11 26; (141).
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Reliability of six prognostic models to predict time-to-first-treatment in patients with chronic lymphocytic leukaemia in early phase. Am J Hematol. 2017 Jun; 92(6):E91-E93.
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Activation-induced cytidine deaminase in antibody diversification and chromosome translocation. Adv Cancer Res. 2012; 113:167-90.
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Increased frequency of the immunoglobulin enhancer HS1,2 allele 2 in coeliac disease. Scand J Gastroenterol. 2004 Nov; 39(11):1083-7.
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Efficacy of immune sera from human immunoglobulin transgenic mice immunized with a peptide mimotope of Cryptococcus neoformans glucuronoxylomannan. Vaccine. 2004 Sep 28; 22(29-30):4062-8.
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Effect of 51p1-related gene copy number (V1-69 locus) on production of hepatitis C-associated cryoglobulins. Clin Exp Immunol. 2001 Jan; 123(1):88-93.
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Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV. J Virol. 1991 Dec; 65(12):6881-91.