"Cytokine TWEAK" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A proteolytically-cleaved membrane glycoprotein and member of the TNF superfamily that is highly expressed in a variety of tissues including heart, pancreas, brain, and peripheral blood lymphocytes. The secreted extracellular form is a weak inducer of APOPTOSIS for some cell types and a ligand for the FN14 RECEPTOR. It mediates activation of NF-KAPPA-B and promotes ANGIOGENESIS and proliferation of ENDOTHELIAL CELLS, as well as expression of cytokines involved in INFLAMMATION.
| Descriptor ID |
D000074049
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| MeSH Number(s) |
D12.644.276.374.750.155 D12.776.467.374.750.155 D23.529.374.750.155
|
| Concept/Terms |
Cytokine TWEAK- Cytokine TWEAK
- TWEAK, Cytokine
- TNF-Related Weak Inducer of Apoptosis
- TNF Related Weak Inducer of Apoptosis
- TWEAK Cytokine
- Cytokine, TWEAK
- Tumor Necrosis Factor Ligand Superfamily Member 12
- Apo3 Ligand
- Ligand, Apo3
|
Below are MeSH descriptors whose meaning is more general than "Cytokine TWEAK".
Below are MeSH descriptors whose meaning is more specific than "Cytokine TWEAK".
This graph shows the total number of publications written about "Cytokine TWEAK" by people in this website by year, and whether "Cytokine TWEAK" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 2 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 4 | 0 | 4 |
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Below are the most recent publications written about "Cytokine TWEAK" by people in Profiles.
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The assessment of the serum levels of TWEAK and prostaglandin F2a in COVID – 19 Turk J Med Sci. 2020 12 17; 50(8):1786-1791.
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TWEAK increases CD74 expression and sensitizes to DDT proinflammatory actions in tubular cells. PLoS One. 2018; 13(6):e0199391.
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Combined utilization of untimed single urine of MCP-1 and TWEAK as a potential indicator for proteinuria in lupus nephritis: A case-control study. Medicine (Baltimore). 2018 Apr; 97(16):e0343.
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TWEAK and RIPK1 mediate a second wave of cell death during AKI. Proc Natl Acad Sci U S A. 2018 04 17; 115(16):4182-4187.
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Soluble Tumor Necrosis Factor (TNF)-Like Weak Inducer of Apoptosis (Tweak) Independently Predicts Subclinical Atherosclerosis in Behcet's Disease. Acta Medica (Hradec Kralove). 2018; 61(3):86-92.
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Sputum TWEAK expression correlates with severity and degree of control in non-eosinophilic childhood asthma. Pediatr Allergy Immunol. 2018 02; 29(1):42-49.
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Bcl3: a regulator of NF-?B inducible by TWEAK in acute kidney injury with anti-inflammatory and antiapoptotic properties in tubular cells. Exp Mol Med. 2017 07 07; 49(7):e352.
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Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) enhances vascular and renal damage induced by hyperlipidemic diet in ApoE-knockout mice. Arterioscler Thromb Vasc Biol. 2009 Dec; 29(12):2061-8.
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Tweak induces proliferation in renal tubular epithelium: a role in uninephrectomy induced renal hyperplasia. J Cell Mol Med. 2009 Sep; 13(9B):3329-42.