"Thyroid Nuclear Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY.
| Descriptor ID |
D000074482
|
| MeSH Number(s) |
D12.776.260.400.871 D12.776.660.823 D12.776.930.888
|
| Concept/Terms |
Thyroid Nuclear Factor 1- Thyroid Nuclear Factor 1
- Thyroid Transcription Factor 1
- TITF-1 Protein
- TITF 1 Protein
- Homeobox Protein Nkx-2.1
- Homeobox Protein Nkx 2.1
- Nkx-2.1, Homeobox Protein
- NK2 Homeobox 1 Protein
- TITF1 Protein
- TTF-1 Thyroid Nuclear Factor
- TTF 1 Thyroid Nuclear Factor
- Thyroid-Specific Enhancer-Binding Protein
- Enhancer-Binding Protein, Thyroid-Specific
- Thyroid Specific Enhancer Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Thyroid Nuclear Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Thyroid Nuclear Factor 1".
This graph shows the total number of publications written about "Thyroid Nuclear Factor 1" by people in this website by year, and whether "Thyroid Nuclear Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 3 | 1 | 4 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
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Below are the most recent publications written about "Thyroid Nuclear Factor 1" by people in Profiles.
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Increased Anaplastic Lymphoma Kinase Activity Induces a Poorly Differentiated Thyroid Carcinoma in Mice. Thyroid. 2019 10; 29(10):1438-1446.
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Thymic Carcinoma With Thyroid Transcription Factor-1 Expression: An Insidious Pitfall. J Thorac Oncol. 2019 Apr; 14(4):e68-e70.
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Spectral CT Imaging of Lung Cancer: Quantitative Analysis of Spectral Parameters and Their Correlation with Tumor Characteristics. Acad Radiol. 2018 11; 25(11):1398-1404.
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Diagnostic and prognostic impact of mucin 1-6 expression in non-small cell lung cancer. Indian J Pathol Microbiol. 2018 Apr-Jun; 61(2):187-191.
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Clinicopathological and molecular implications of aberrant thyroid transcription factor-1 expression in colorectal carcinomas: an immunohistochemical analysis of 1319 cases using three different antibody clones. Histopathology. 2018 Feb; 72(3):423-432.
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High-resolution melting analysis (HRM) for mutational screening of Dnajc17 gene in patients affected by thyroid dysgenesis. J Endocrinol Invest. 2018 Jun; 41(6):711-717.
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p40 & thyroid transcription factor-1 immunohistochemistry: A useful panel to characterize non-small cell lung carcinoma-not otherwise specified (NSCLC-NOS) category. Indian J Med Res. 2017 Jul; 146(1):42-48.
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Immunoprofiling of glial tumours of the neurohypophysis suggests a common pituicytic origin of neoplastic cells. Pituitary. 2017 Apr; 20(2):211-217.
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Predictive factors for EGFR-tyrosine kinase inhibitor retreatment in patients with EGFR-mutated non-small-cell lung cancer - A multicenter retrospective SEQUENCE study. Lung Cancer. 2017 02; 104:58-64.
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Pulmonary pathology of severe acute respiratory syndrome in Toronto. Mod Pathol. 2005 Jan; 18(1):1-10.