"Acetazolamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
| Descriptor ID |
D000086
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| MeSH Number(s) |
D02.886.675.867.060 D03.383.129.708.867.060
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Acetazolamide".
Below are MeSH descriptors whose meaning is more specific than "Acetazolamide".
This graph shows the total number of publications written about "Acetazolamide" by people in this website by year, and whether "Acetazolamide" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2017 | 4 | 2 | 6 |
| 2018 | 3 | 1 | 4 |
| 2020 | 1 | 1 | 2 |
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Below are the most recent publications written about "Acetazolamide" by people in Profiles.
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Is carbonic anhydrase inhibition useful as a complementary therapy of Covid-19 infection? J Enzyme Inhib Med Chem. 2021 Dec; 36(1):1230-1235.
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The potential effectiveness of acetazolamide in the prevention of acute kidney injury in COVID-19: A hypothesis. Eur J Pharmacol. 2020 Dec 05; 888:173487.
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COVID-19 Lung Injury and High-Altitude Pulmonary Edema. A False Equation with Dangerous Implications. Ann Am Thorac Soc. 2020 08; 17(8):918-921.
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Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials. Med Hypotheses. 2020 Oct; 143:109851.
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Respiratory conditions in coronavirus disease 2019 (COVID-19): Important considerations regarding novel treatment strategies to reduce mortality. Med Hypotheses. 2020 Jul; 140:109760.
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Rationale and design of the ADVOR (Acetazolamide in Decompensated Heart Failure with Volume Overload) trial. Eur J Heart Fail. 2018 11; 20(11):1591-1600.
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Treatment for HIV-associated cryptococcal meningitis. Cochrane Database Syst Rev. 2018 07 25; 7:CD005647.
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Acetazolamide and Cardiac Failure. Clin Drug Investig. 2018 Jul; 38(7):649-650.
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Effect of acetazolamide and methazolamide on diaphragm and dorsiflexor fatigue: a randomized controlled trial. J Appl Physiol (1985). 2018 09 01; 125(3):770-779.
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Acetazolamide and N-acetylcysteine in the treatment of chronic mountain sickness (Monge's disease). Respir Physiol Neurobiol. 2017 12; 246:1-8.