Organic Cation Transporter 2
"Organic Cation Transporter 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Organic cation transporter consisting of twelve transmembrane domains and expressed primarily in the kidney. It transports a wide range of metabolites, drugs, and neurotransmitters from the blood to the KIDNEY TUBULES, including DOPAMINE; SEROTONIN; CHOLINE; and CISPLATIN.
| Descriptor ID |
D000075102
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| MeSH Number(s) |
D12.776.157.530.450.250.812.625 D12.776.157.530.937.612.625 D12.776.543.585.450.250.812.625 D12.776.543.585.937.701.625
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Organic Cation Transporter 2".
Below are MeSH descriptors whose meaning is more specific than "Organic Cation Transporter 2".
This graph shows the total number of publications written about "Organic Cation Transporter 2" by people in this website by year, and whether "Organic Cation Transporter 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Organic Cation Transporter 2" by people in Profiles.
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SLC22A2 variants and dolutegravir levels correlate with psychiatric symptoms in persons with HIV. J Antimicrob Chemother. 2019 04 01; 74(4):1035-1043.
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Assessment of Substrate-Dependent Ligand Interactions at the Organic Cation Transporter OCT2 Using Six Model Substrates. Mol Pharmacol. 2018 09; 94(3):1057-1068.
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BET proteins are a key component of immunoglobulin gene expression. Epigenomics. 2017 04; 9(4):393-406.
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Contribution of the organic anion transporter OAT2 to the renal active tubular secretion of creatinine and mechanism for serum creatinine elevations caused by cobicistat. Kidney Int. 2014 Aug; 86(2):350-7.