"Bromodeoxyuridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
| Descriptor ID |
D001973
|
| MeSH Number(s) |
D03.383.742.680.852.300.150 D13.570.230.430.196 D13.570.685.852.300.150
|
| Concept/Terms |
Bromodeoxyuridine- Bromodeoxyuridine
- Bromouracil Deoxyriboside
- Deoxyriboside, Bromouracil
- 5-Bromo-2'-deoxyuridine
- 5 Bromo 2' deoxyuridine
- BrdU
- BUdR
- 5-Bromodeoxyuridine
- 5 Bromodeoxyuridine
- Broxuridine
|
Below are MeSH descriptors whose meaning is more general than "Bromodeoxyuridine".
Below are MeSH descriptors whose meaning is more specific than "Bromodeoxyuridine".
This graph shows the total number of publications written about "Bromodeoxyuridine" by people in this website by year, and whether "Bromodeoxyuridine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bromodeoxyuridine" by people in Profiles.
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Enriched environment promotes post-stroke neurogenesis through NF-?B-mediated secretion of IL-17A from astrocytes. Brain Res. 2018 05 15; 1687:20-31.
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miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib. J Hepatol. 2017 11; 67(5):966-978.
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IFN-?- and IL-10-expressing virus epitope-specific Foxp3(+) T reg cells in the central nervous system during encephalomyelitis. J Exp Med. 2011 Aug 01; 208(8):1571-7.
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Dose-dependent inhibition of BrdU detection in the cell proliferation ELISA by culture medium proteins. J Immunoassay Immunochem. 2009; 30(3):348-57.
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Identification of pulmonary Oct-4+ stem/progenitor cells and demonstration of their susceptibility to SARS coronavirus (SARS-CoV) infection in vitro. Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25):9530-5.
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The nucleocapsid protein of severe acute respiratory syndrome-coronavirus inhibits the activity of cyclin-cyclin-dependent kinase complex and blocks S phase progression in mammalian cells. J Biol Chem. 2006 Apr 21; 281(16):10669-81.
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Infectious bronchitis coronavirus induces cell-cycle perturbations. Adv Exp Med Biol. 2006; 581:357-62.
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The cell cycle and virus infection. Methods Mol Biol. 2005; 296:197-218.
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Remyelination, axonal sparing, and locomotor recovery following transplantation of glial-committed progenitor cells into the MHV model of multiple sclerosis. Exp Neurol. 2004 Jun; 187(2):254-65.
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Antiviral activity of ganciclovir elaidic acid ester against herpesviruses. Antiviral Res. 2000 Mar; 45(3):157-67.