Triggering Receptor Expressed on Myeloid Cells-1
"Triggering Receptor Expressed on Myeloid Cells-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An approximately 230 amino acid membrane glycoprotein characterized by an IMMUNOGLOBULIN V-SET DOMAIN in its N-terminal half. It is expressed by MONOCYTES and NEUTROPHILS in response to INFLAMMATION related to bacterial and fungal infections. It triggers the release of pro-inflammatory CHEMOKINES; CYTOKINES, and expression of cell activation markers and is a critical regulator of SEPTIC SHOCK.
| Descriptor ID |
D000073871
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| MeSH Number(s) |
D12.776.395.550.919 D12.776.543.550.919 D12.776.543.750.705.985
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Triggering Receptor Expressed on Myeloid Cells-1".
Below are MeSH descriptors whose meaning is more specific than "Triggering Receptor Expressed on Myeloid Cells-1".
This graph shows the total number of publications written about "Triggering Receptor Expressed on Myeloid Cells-1" by people in this website by year, and whether "Triggering Receptor Expressed on Myeloid Cells-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2018 | 4 | 0 | 4 |
| 2019 | 0 | 1 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "Triggering Receptor Expressed on Myeloid Cells-1" by people in Profiles.
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Evaluation of the relationship between TREM-1/TREM-2 ratio and clinical course in COVID-19 pneumonia. Int J Clin Pract. 2021 Oct; 75(10):e14697.
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Increased sTREM-1 plasma concentrations are associated with poor clinical outcomes in patients with COVID-19. Biosci Rep. 2021 07 30; 41(7).
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COVID-19 risk stratification algorithms based on sTREM-1 and IL-6 in emergency department. J Allergy Clin Immunol. 2021 01; 147(1):99-106.e4.
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Association between genotypes of rs34436714 of NLRP12 and serum tumor necrosis factor-alpha in inflammatory bowel disease: A case-control study. Medicine (Baltimore). 2019 Jun; 98(23):e15913.
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Utility of neutrophil CD64 and serum TREM-1 in distinguishing bacterial infection from disease flare in SLE and ANCA-associated vasculitis. Clin Rheumatol. 2019 Apr; 38(4):997-1005.
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TREM-1 Neutrophil Activation Pathway Is Suppressed in Eosinophilic Nasal Polyps. Am J Rhinol Allergy. 2018 Sep; 32(5):359-368.
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TREM-1 Inhibition Restores Impaired Autophagy Activity and Reduces Colitis in Mice. J Crohns Colitis. 2018 Jan 24; 12(2):230-244.
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Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) and its soluble in the plasma form (sTREM-1) as a diagnostic biomarker in neonatal sepsis. Folia Med Cracov. 2018; 58(2):15-19.
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Presepsin: A potential biomarker of PJI? A comparative analysis with known and new infection biomarkers. Int J Immunopathol Pharmacol. 2018 Jan-Dec; 31:394632017749356.
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Antimicrobial cathelicidin peptide LL-37 induces NET formation and suppresses the inflammatory response in a mouse septic model. Mol Med Rep. 2017 Oct; 16(4):5618-5626.